|
US8754114B2
(en)
|
2010-12-22 |
2014-06-17 |
Incyte Corporation |
Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
|
|
WO2012135631A1
(en)
|
2011-03-30 |
2012-10-04 |
Arrien Pharmaeuticals Llc |
Substituted 5-(pyrazin-2-yl)-1h-pyrazolo [3, 4-b] pyridine and pyrazolo [3, 4-b] pyridine derivatives as protein kinase inhibitors
|
|
GB201204985D0
(en)
|
2012-03-21 |
2012-05-02 |
Genentech Inc |
Compounds
|
|
EP2844660B1
(en)
*
|
2012-05-02 |
2017-11-01 |
Southern Research Institute |
Triazolopyridazine compounds, use as inhibitors of the kinase lrrk2, and methods for preparation thereof
|
|
CN102675310B
(zh)
*
|
2012-05-09 |
2014-12-24 |
林辉 |
制备吡唑并芳杂环化合物的方法
|
|
ES2704744T3
(es)
|
2012-06-13 |
2019-03-19 |
Incyte Holdings Corp |
Compuestos tricíclicos sustituidos como inhibidores de FGFR
|
|
WO2014001973A1
(en)
|
2012-06-29 |
2014-01-03 |
Pfizer Inc. |
NOVEL 4-(SUBSTITUTED-AMINO)-7H-PYRROLO[2,3-d]PYRIMIDINES AS LRRK2 INHIBITORS
|
|
US9388185B2
(en)
|
2012-08-10 |
2016-07-12 |
Incyte Holdings Corporation |
Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
|
|
MD20150037A2
(ro)
|
2012-11-08 |
2015-11-30 |
Pfizer Inc. |
Compuşi heteroaromatici şi utilizarea lor ca liganzi de dopamină D1
|
|
US9266892B2
(en)
|
2012-12-19 |
2016-02-23 |
Incyte Holdings Corporation |
Fused pyrazoles as FGFR inhibitors
|
|
WO2014134772A1
(en)
|
2013-03-04 |
2014-09-12 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
|
WO2014134774A1
(en)
|
2013-03-04 |
2014-09-12 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
|
US9440952B2
(en)
|
2013-03-04 |
2016-09-13 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
|
WO2014134776A1
(en)
|
2013-03-04 |
2014-09-12 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
|
TW201444850A
(zh)
*
|
2013-03-15 |
2014-12-01 |
Ipsen Pharma Sas |
巨環lrrk2激酶抑制劑
|
|
US20140288043A1
(en)
*
|
2013-03-19 |
2014-09-25 |
Genentech, Inc. |
Pyrazolopyridine compounds
|
|
TW201533043A
(zh)
*
|
2013-04-18 |
2015-09-01 |
Lundbeck & Co As H |
作爲lrrk2抑制劑的芳基吡咯并吡啶衍生化合物
|
|
EA035095B1
(ru)
|
2013-04-19 |
2020-04-27 |
Инсайт Холдингс Корпорейшн |
Бициклические гетероциклы в качестве ингибиторов fgfr
|
|
WO2015026683A1
(en)
|
2013-08-22 |
2015-02-26 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
|
JP6487921B2
(ja)
*
|
2013-12-17 |
2019-03-20 |
ファイザー・インク |
LRRK2阻害薬としての新規の3,4−二置換−1H−ピロロ[2,3−b]ピリジンおよび4,5−二置換−7H−ピロロ[2,3−c]ピリダジン
|
|
CN103819396B
(zh)
*
|
2014-02-26 |
2016-06-15 |
四川大学 |
一种手性的1-(3,5-二氯吡啶-4-基)-乙醇的合成方法
|
|
EP3134405B1
(en)
|
2014-04-25 |
2019-08-28 |
Pfizer Inc |
Heteroaromatic compounds and their use as dopamine d1 ligands
|
|
US10851105B2
(en)
|
2014-10-22 |
2020-12-01 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
MX373169B
(es)
|
2015-02-20 |
2020-04-24 |
Incyte Holdings Corp |
Heterociclos bicíclicos como inhibidores de receptores del factor de crecimiento fibroblástico (fgfr).
|
|
WO2016134294A1
(en)
|
2015-02-20 |
2016-08-25 |
Incyte Corporation |
Bicyclic heterocycles as fgfr4 inhibitors
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
AU2016295604B2
(en)
*
|
2015-07-23 |
2019-08-01 |
Glaxosmithkline Intellectual Property Development Limited |
Compounds
|
|
KR102161364B1
(ko)
|
2015-09-14 |
2020-09-29 |
화이자 인코포레이티드 |
LRRK2 억제제로서 이미다조[4,5-c]퀴놀린 및 이미다조[4,5-c][1,5]나프티리딘 유도체
|
|
US11214565B2
(en)
|
2015-11-20 |
2022-01-04 |
Denali Therapeutics Inc. |
Compound, compositions, and methods
|
|
JP2018537502A
(ja)
|
2015-12-16 |
2018-12-20 |
サウザーン リサーチ インスチチュート |
ピロロピリミジン化合物、キナーゼlrrk2阻害剤としての使用、及びその調製方法
|
|
US11028080B2
(en)
|
2016-03-11 |
2021-06-08 |
Denali Therapeutics Inc. |
Substituted pyrimidines as LRKK2 inhibitors
|
|
MD3472153T2
(ro)
|
2016-06-16 |
2022-03-31 |
Denali Therapeutics Inc |
Pirimidin-2-ilamino-1H-pirazoli în calitate de inhibitori L RRK2 pentru utilizare în tratamentul tulburărilor neurodegenerative
|
|
TW201811799A
(zh)
|
2016-09-09 |
2018-04-01 |
美商英塞特公司 |
吡唑并嘧啶化合物及其用途
|
|
WO2018049214A1
(en)
|
2016-09-09 |
2018-03-15 |
Incyte Corporation |
Pyrazolopyridine derivatives as hpk1 modulators and uses thereof for the treatment of cancer
|
|
US10280164B2
(en)
|
2016-09-09 |
2019-05-07 |
Incyte Corporation |
Pyrazolopyridone compounds and uses thereof
|
|
UA125650C2
(uk)
*
|
2016-09-09 |
2022-05-11 |
Інсайт Корпорейшн |
Регулятори нрk1 на основі похідних піразолопіридину та їх застосування для лікування раку
|
|
US10040211B2
(en)
|
2016-12-09 |
2018-08-07 |
Bettcher Industries, Inc. |
Power operated rotary knife
|
|
US20180228786A1
(en)
|
2017-02-15 |
2018-08-16 |
Incyte Corporation |
Pyrazolopyridine compounds and uses thereof
|
|
KR101923852B1
(ko)
|
2017-02-24 |
2018-11-29 |
재단법인 대구경북첨단의료산업진흥재단 |
혈액 뇌관문을 통과할 수 있는 화합물을 유효성분으로 함유하는 뇌암의 예방 또는 치료용 약학적 조성물
|
|
EP3592740B1
(en)
|
2017-03-10 |
2022-02-09 |
Pfizer Inc. |
Cyclic substituted imidazo[4,5-c]quinoline derivatives
|
|
WO2018163066A1
(en)
|
2017-03-10 |
2018-09-13 |
Pfizer Inc. |
Novel imidazo[4,5-c]quinoline derivatives as lrrk2 inhibitors
|
|
JP7352284B2
(ja)
*
|
2017-05-15 |
2023-09-28 |
ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミシガン |
LSD-1インヒビターとしてのピロロ〔2,3-c〕ピリジン及び関連類似体
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
US10722495B2
(en)
|
2017-09-08 |
2020-07-28 |
Incyte Corporation |
Cyanoindazole compounds and uses thereof
|
|
WO2019164847A1
(en)
|
2018-02-20 |
2019-08-29 |
Incyte Corporation |
Indazole compounds and uses thereof
|
|
US10800761B2
(en)
|
2018-02-20 |
2020-10-13 |
Incyte Corporation |
Carboxamide compounds and uses thereof
|
|
US10745388B2
(en)
|
2018-02-20 |
2020-08-18 |
Incyte Corporation |
Indazole compounds and uses thereof
|
|
US11299473B2
(en)
|
2018-04-13 |
2022-04-12 |
Incyte Corporation |
Benzimidazole and indole compounds and uses thereof
|
|
MA52493A
(fr)
|
2018-05-04 |
2021-03-10 |
Incyte Corp |
Sels d'un inhibiteur de fgfr
|
|
CR20200590A
(es)
|
2018-05-04 |
2021-04-26 |
Incyte Corp |
Formas sólidas de un inhibidor de fgfr y procesos para prepararlas
|
|
ES2738911A1
(es)
|
2018-07-25 |
2020-01-27 |
Consejo Superior Investigacion |
Procedimiento para depositar elementos sobre un sustrato de interes y dispositivo
|
|
US10899755B2
(en)
|
2018-08-08 |
2021-01-26 |
Incyte Corporation |
Benzothiazole compounds and uses thereof
|
|
ES2744304B2
(es)
|
2018-08-24 |
2020-06-22 |
Consejo Superior Investigacion |
Compuestos inhibidores de LRRK2 y su uso para el tratamiento de enfermedades neurodegenerativas
|
|
ES2973117T3
(es)
|
2018-09-25 |
2024-06-18 |
Incyte Corp |
Compuestos de pirazolo[4,3-d]pirimidina como moduladores de ALK2 y/o FGFR
|
|
WO2020185532A1
(en)
|
2019-03-08 |
2020-09-17 |
Incyte Corporation |
Methods of treating cancer with an fgfr inhibitor
|
|
WO2021007269A1
(en)
|
2019-07-09 |
2021-01-14 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
MX2022001562A
(es)
|
2019-08-06 |
2022-04-26 |
Incyte Corp |
Formas solidas de un inhibidor de la cinasa 1 del progenitor hematopoyetico (hpk1).
|
|
WO2021067374A1
(en)
|
2019-10-01 |
2021-04-08 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
TWI891666B
(zh)
|
2019-10-14 |
2025-08-01 |
美商英塞特公司 |
作為fgfr抑制劑之雙環雜環
|
|
WO2021076728A1
(en)
|
2019-10-16 |
2021-04-22 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
EP4069696A1
(en)
|
2019-12-04 |
2022-10-12 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
BR112022010664A2
(pt)
|
2019-12-04 |
2022-08-16 |
Incyte Corp |
Derivados de um inibidor de fgfr
|
|
WO2021146424A1
(en)
|
2020-01-15 |
2021-07-22 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
WO2022198112A1
(en)
|
2021-03-19 |
2022-09-22 |
Arvinas Operations, Inc. |
Indazole based compounds and associated methods of use
|
|
TW202304459A
(zh)
|
2021-04-12 |
2023-02-01 |
美商英塞特公司 |
包含fgfr抑制劑及nectin-4靶向劑之組合療法
|
|
WO2022261159A1
(en)
|
2021-06-09 |
2022-12-15 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
EP4352059A1
(en)
|
2021-06-09 |
2024-04-17 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
WO2023076404A1
(en)
|
2021-10-27 |
2023-05-04 |
Aria Pharmaceuticals, Inc. |
Methods for treating systemic lupus erythematosus
|
|
AU2024352092A1
(en)
|
2023-09-28 |
2026-04-09 |
Arvinas Operations, Inc. |
Benzimidazole and benzimidazolone based protac compounds for the targeted degradation of leucine rich repeat kinase 2 (lrrk2)
|
|
WO2025248032A1
(en)
|
2024-05-31 |
2025-12-04 |
Syngenta Crop Protection Ag |
Pesticidally active indazole compounds
|