JP2012530761A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012530761A5 JP2012530761A5 JP2012516745A JP2012516745A JP2012530761A5 JP 2012530761 A5 JP2012530761 A5 JP 2012530761A5 JP 2012516745 A JP2012516745 A JP 2012516745A JP 2012516745 A JP2012516745 A JP 2012516745A JP 2012530761 A5 JP2012530761 A5 JP 2012530761A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- immunogenic composition
- composition according
- domain
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21995809P | 2009-06-24 | 2009-06-24 | |
| US61/219,958 | 2009-06-24 | ||
| PCT/EP2010/059006 WO2010149743A2 (en) | 2009-06-24 | 2010-06-24 | Vaccine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012530761A JP2012530761A (ja) | 2012-12-06 |
| JP2012530761A5 true JP2012530761A5 (enExample) | 2013-08-15 |
| JP5796011B2 JP5796011B2 (ja) | 2015-10-21 |
Family
ID=42797417
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012516745A Active JP5796011B2 (ja) | 2009-06-24 | 2010-06-24 | ワクチン |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8889146B2 (enExample) |
| EP (1) | EP2445527A2 (enExample) |
| JP (1) | JP5796011B2 (enExample) |
| KR (1) | KR20120093811A (enExample) |
| CN (1) | CN102548578A (enExample) |
| AU (1) | AU2010264686A1 (enExample) |
| CA (1) | CA2766205A1 (enExample) |
| EA (1) | EA201270062A1 (enExample) |
| IL (1) | IL217008A0 (enExample) |
| MX (1) | MX2012000036A (enExample) |
| SG (1) | SG176807A1 (enExample) |
| WO (1) | WO2010149743A2 (enExample) |
| ZA (1) | ZA201109164B (enExample) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5711972B2 (ja) * | 2007-12-24 | 2015-05-07 | アイディー バイオメディカル コーポレイション オブ ケベック | 組換えｒｓｖ抗原 |
| PT2445526T (pt) | 2009-06-24 | 2016-08-16 | Glaxosmithkline Biologicals Sa | Antigénios de rsv recombinantes |
| PL3178490T3 (pl) | 2009-07-15 | 2022-08-01 | Glaxosmithkline Biologicals S.A. | Kompozycje białka f rsv i sposoby ich wytwarzania |
| PL2667892T3 (pl) | 2011-01-26 | 2019-09-30 | Glaxosmithkline Biologicals Sa | Schemat szczepień przeciwko rsv |
| CA2825722A1 (en) * | 2011-01-28 | 2012-08-02 | Medimmune, Llc | Expression of soluble viral fusion glycoproteins in mammalian cells |
| ES2651143T3 (es) | 2011-05-13 | 2018-01-24 | Glaxosmithkline Biologicals Sa | Antígenos de F de prefusión del VRS |
| WO2013031827A1 (ja) | 2011-08-29 | 2013-03-07 | 国立大学法人徳島大学 | Rsv粘膜ワクチン |
| TR201808733T4 (tr) * | 2011-10-03 | 2018-07-23 | Mx Adjuvac Ab | Kanser tedavisini ve gıda ile ilgili bileşikleri içeren tıp alanlarında amfipatik veya hidrofobik moleküller için taşıyıcı olarak nano-parçacıklar, preparasyon için proses ve bunların kullanımı. |
| EP2828293B1 (en) * | 2012-03-20 | 2017-10-25 | Humabs Biomed S.A. | Antibodies that neutralize rsv, mpv and pvm and uses thereof |
| EA039682B1 (ru) * | 2012-06-04 | 2022-02-28 | Хумабс Биомед Са | Антитела, нейтрализующие rsv, mpv и pvm, и их применения |
| CN102743750B (zh) * | 2012-07-09 | 2013-11-20 | 江苏省农业科学院 | 一种复方免疫增强剂、禽用疫苗及其制备方法 |
| BR112015002131B1 (pt) | 2012-08-01 | 2022-11-01 | Bavarian Nordic A/S | Vírus vaccinia ankara modificado (mva) recombinante, composição farmacêutica e uso do referido mva recombinante |
| US20140037680A1 (en) | 2012-08-06 | 2014-02-06 | Glaxosmithkline Biologicals, S.A. | Novel method |
| WO2014024026A1 (en) | 2012-08-06 | 2014-02-13 | Glaxosmithkline Biologicals S.A. | Method for eliciting in infants an immune response against rsv and b. pertussis |
| EP2922570A1 (en) * | 2012-11-20 | 2015-09-30 | GlaxoSmithKline Biologicals SA | Rsv f prefusion trimers |
| US9738689B2 (en) | 2013-03-13 | 2017-08-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Prefusion RSV F proteins and their use |
| CN105473604B (zh) * | 2013-03-13 | 2021-01-22 | 美国政府(由卫生和人类服务部的部长所代表) | 融合前rsv f蛋白和其用途 |
| US9060975B2 (en) * | 2013-03-14 | 2015-06-23 | Mucosis Bv | Heat-stable respiratory syncytial virus F protein oligomers and their use in immunological compositions |
| BR112015025392A2 (pt) * | 2013-04-08 | 2017-10-10 | Medimmune Llc | composição de vacina e método de utilização |
| CN110590916A (zh) | 2013-04-25 | 2019-12-20 | 扬森疫苗与预防公司 | 稳定化的可溶性融合前rsv f多肽 |
| KR102313153B1 (ko) | 2013-06-17 | 2021-10-15 | 얀센 백신스 앤드 프리벤션 비.브이. | 안정화된 가용성 예비융합 ｒｓｖ ｆ 폴리펩타이드 |
| KR20160040290A (ko) | 2013-08-05 | 2016-04-12 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 조합 면역원성 조성물 |
| EP3035959A1 (en) | 2013-08-21 | 2016-06-29 | CureVac AG | Combination vaccine |
| US9322037B2 (en) * | 2013-09-06 | 2016-04-26 | President And Fellows Of Harvard College | Cas9-FokI fusion proteins and uses thereof |
| EP3236998A1 (en) | 2014-12-24 | 2017-11-01 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Recombinant metapneumovirus f proteins and their use |
| WO2016144675A1 (en) * | 2015-03-06 | 2016-09-15 | Medimmune, Llc | Vaccine dose and use thereof |
| JP7189014B2 (ja) | 2015-07-07 | 2022-12-13 | ヤンセン ファッシンズ アンド プリベンション ベーフェー | Ｒｓｖに対するワクチン |
| US10457708B2 (en) | 2015-07-07 | 2019-10-29 | Janssen Vaccines & Prevention B.V. | Stabilized soluble pre-fusion RSV F polypeptides |
| MA47016A (fr) | 2015-10-22 | 2018-08-29 | Modernatx Inc | Vaccins contre les virus respiratoires |
| MY205060A (en) | 2015-12-23 | 2024-09-30 | Pfizer | Rsv f protein mutants |
| KR20220041966A (ko) | 2016-04-05 | 2022-04-01 | 얀센 백신스 앤드 프리벤션 비.브이. | 안정화된 용해성 융합-전 rsv f 단백질 |
| BR112018070323A2 (pt) | 2016-04-05 | 2019-01-29 | Janssen Vaccines & Prevention Bv | vacina contra rsv |
| CN105693829B (zh) * | 2016-04-14 | 2022-03-15 | 青岛易邦生物工程有限公司 | 一种b型禽偏肺病毒f蛋白 |
| MA45052A (fr) | 2016-05-18 | 2019-03-27 | Modernatx Inc | Polynucléotides codant pour jagged1 pour le traitement du syndrome d'alagille |
| IL264119B2 (en) | 2016-05-30 | 2023-04-01 | Janssen Vaccines Prevention B V | f proteins of rsv are stabilized before fusion |
| WO2017207477A1 (en) | 2016-05-30 | 2017-12-07 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion rsv f proteins |
| CN106119287B (zh) * | 2016-08-29 | 2019-10-11 | 广东华南疫苗股份有限公司 | 一种表达呼吸道合胞病毒f蛋白的重组载体及方法 |
| US11078239B2 (en) * | 2016-10-25 | 2021-08-03 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Prefusion PIV F immunogens and their use |
| TWI683826B (zh) * | 2016-11-22 | 2020-02-01 | 國立臺灣大學 | 重組ｒｓｖ抗原 |
| MA50335A (fr) | 2016-12-08 | 2020-08-19 | Modernatx Inc | Vaccins à acide nucléique contre des virus respiratoires |
| EP3595676A4 (en) | 2017-03-17 | 2021-05-05 | Modernatx, Inc. | RNA VACCINES AGAINST ZOONOSES |
| CA3061678A1 (en) | 2017-05-15 | 2018-11-22 | Janssen Vaccines & Prevention B.V. | Stable virus-containing composition |
| KR102658198B1 (ko) | 2017-05-15 | 2024-04-16 | 얀센 백신스 앤드 프리벤션 비.브이. | 안정한 바이러스 함유 조성물 |
| AU2018267971A1 (en) | 2017-05-17 | 2019-11-07 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against RSV infection |
| SG11202001458SA (en) | 2017-09-15 | 2020-03-30 | Janssen Vaccines & Prevention Bv | Method for the safe induction of immunity against rsv |
| WO2019063844A1 (en) * | 2017-09-29 | 2019-04-04 | Universiteit Antwerpen | VACCINATION AGAINST SYNCYTIAL RESPIRATORY VIRUS |
| WO2019092002A1 (en) * | 2017-11-07 | 2019-05-16 | Valneva Se | Pharmaceutical compositions for treatment or prevention of viral infections |
| WO2019148101A1 (en) | 2018-01-29 | 2019-08-01 | Modernatx, Inc. | Rsv rna vaccines |
| JOP20210106A1 (ar) | 2018-11-13 | 2023-01-30 | Janssen Vaccines And Prevention B V | بروتينات rsv f سابقة الاندماج مستقرة |
| WO2020167813A1 (en) * | 2019-02-11 | 2020-08-20 | Emory University | Chimeric rsv and hmpv f proteins, immunogenic compositions, and methods of use |
| US11351242B1 (en) | 2019-02-12 | 2022-06-07 | Modernatx, Inc. | HMPV/hPIV3 mRNA vaccine composition |
| CN114127101A (zh) | 2019-05-20 | 2022-03-01 | 瓦尔尼瓦公司 | 用于治疗或预防呼吸道感染的亚单位疫苗 |
| JP2023513073A (ja) * | 2020-01-30 | 2023-03-30 | モデルナティエックス インコーポレイテッド | 呼吸器系ウイルス免疫化組成物 |
| TW202233232A (zh) | 2020-11-06 | 2022-09-01 | 法商賽諾菲公司 | 遞送mRNA疫苗的脂質奈米顆粒 |
| MX2023009447A (es) * | 2021-02-12 | 2023-10-06 | Merck Sharp & Dohme Llc | Anticuerpos que se unen a metapneumovirus, proteínas antigénicas de metapneumovirus, y usos de los mismos. |
| AU2022221983A1 (en) | 2021-02-19 | 2023-08-17 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion rsv fb antigens |
| KR20240118795A (ko) * | 2021-11-30 | 2024-08-05 | 사노피 파스퇴르 인크 | 인간 메타뉴모바이러스 바이러스 벡터-기반 백신 |
| KR20240118798A (ko) * | 2021-11-30 | 2024-08-05 | 사노피 파스퇴르 인크 | 인간 메타뉴모바이러스 백신 |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235877A (en) | 1979-06-27 | 1980-11-25 | Merck & Co., Inc. | Liposome particle containing viral or bacterial antigenic subunit |
| US4372945A (en) | 1979-11-13 | 1983-02-08 | Likhite Vilas V | Antigen compounds |
| IL61904A (en) | 1981-01-13 | 1985-07-31 | Yeda Res & Dev | Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same |
| US4436727A (en) | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
| US4866034A (en) | 1982-05-26 | 1989-09-12 | Ribi Immunochem Research Inc. | Refined detoxified endotoxin |
| SE8205892D0 (sv) | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
| US4707543A (en) | 1985-09-17 | 1987-11-17 | The United States Of America As Represented By The Secretary Of The Army | Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines |
| US5149650A (en) | 1986-01-14 | 1992-09-22 | University Of North Carolina At Chapel Hill | Vaccines for human respiratory virus |
| US4877611A (en) | 1986-04-15 | 1989-10-31 | Ribi Immunochem Research Inc. | Vaccine containing tumor antigens and adjuvants |
| CA1331443C (en) | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Saponin adjuvant |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| US5726292A (en) | 1987-06-23 | 1998-03-10 | Lowell; George H. | Immuno-potentiating systems for preparation of immunogenic materials |
| US5278302A (en) | 1988-05-26 | 1994-01-11 | University Patents, Inc. | Polynucleotide phosphorodithioates |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| US6245549B1 (en) * | 1990-06-28 | 2001-06-12 | Connaught Laboratories Limited | Production of virus and purification of viral envelope proteins for vaccine use |
| GB9120221D0 (en) | 1991-09-23 | 1991-11-06 | Smithkline Beecham Biolog | Novel compounds |
| GB9200117D0 (en) | 1992-01-06 | 1992-02-26 | Connaught Lab | Production of recombinant chimeric proteins for vaccine use |
| NZ253137A (en) | 1992-06-25 | 1996-08-27 | Smithkline Beecham Biolog | Vaccine comprising antigen and/or antigenic composition, qs21 (quillaja saponaria molina extract) and 3 de-o-acylated monophosphoryl lipid a. |
| EP0689454B2 (en) | 1993-03-23 | 2005-02-23 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Vaccine compositions containing 3-o deacylated monophosphoryl lipid a |
| US5961970A (en) | 1993-10-29 | 1999-10-05 | Pharmos Corporation | Submicron emulsions as vaccine adjuvants |
| ES2149340T3 (es) | 1993-11-17 | 2000-11-01 | Om Pharma | Disacaridos de glucosamina, metodo para su preparacion, composicion farmaceutica que los comprende, y su uso. |
| WO1995026204A1 (en) | 1994-03-25 | 1995-10-05 | Isis Pharmaceuticals, Inc. | Immune stimulation by phosphorothioate oligonucleotide analogs |
| FR2718452B1 (fr) | 1994-04-06 | 1996-06-28 | Pf Medicament | Elément d'immunogène, agent immunogène, composition pharmaceutique et procédé de préparation. |
| DE69535905D1 (de) | 1994-07-15 | 2009-02-26 | Coley Pharm Group Inc | Immunomodulatorische Oligonukleotide |
| AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| US5666153A (en) | 1995-10-03 | 1997-09-09 | Virtual Shopping, Inc. | Retractable teleconferencing apparatus |
| US5856462A (en) | 1996-09-10 | 1999-01-05 | Hybridon Incorporated | Oligonucleotides having modified CpG dinucleosides |
| US6113918A (en) | 1997-05-08 | 2000-09-05 | Ribi Immunochem Research, Inc. | Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors |
| US6303347B1 (en) | 1997-05-08 | 2001-10-16 | Corixa Corporation | Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors |
| US6764840B2 (en) | 1997-05-08 | 2004-07-20 | Corixa Corporation | Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors |
| US7208161B1 (en) | 1997-05-23 | 2007-04-24 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Production of attenuated parainfluenza virus vaccines from cloned nucleotide sequences |
| WO1999014334A1 (en) | 1997-09-19 | 1999-03-25 | American Cyanamid Company | Peptides derived from the attachment (g) protein of respiratory syncytial virus |
| GB9727262D0 (en) | 1997-12-24 | 1998-02-25 | Smithkline Beecham Biolog | Vaccine |
| AU7924598A (en) | 1998-06-08 | 1999-12-30 | Sca Emballage France | Fast flattening packaging |
| HUP0102475A3 (en) | 1998-06-30 | 2001-12-28 | Om Pharma | Novel acyl pseudodipeptides, preparation method and pharmaceutical compositions containing same |
| DE122007000087I1 (de) | 1998-10-16 | 2008-03-27 | Glaxosmithkline Biolog Sa | Adjuvanzsysteme und impfstoffe |
| US6551600B2 (en) | 1999-02-01 | 2003-04-22 | Eisai Co., Ltd. | Immunological adjuvant compounds compositions and methods of use thereof |
| US20040006242A1 (en) | 1999-02-01 | 2004-01-08 | Hawkins Lynn D. | Immunomodulatory compounds and method of use thereof |
| AU1581400A (en) | 1999-12-22 | 2001-07-03 | Om Pharma | Acyl pseudopeptides bearing a functionalised auxiliary spacer |
| US20040161846A1 (en) | 2000-11-22 | 2004-08-19 | Mason Anthony John | Method of expression and agents identified thereby |
| ES2330201T3 (es) | 2001-01-26 | 2009-12-07 | Selexis S.A. | Regiones de union a la matriz y metodos para el uso de las mismas. |
| MXPA03008154A (es) | 2001-03-09 | 2004-11-12 | Id Biomedical Corp Quebec | Novedoso adyuvante de vacuna de proteosoma-liposacarido. |
| ATE404561T1 (de) | 2001-04-17 | 2008-08-15 | Dainippon Sumitomo Pharma Co | Neue adeninderivate |
| US20040014779A1 (en) | 2001-11-16 | 2004-01-22 | 3M Innovative Properties Company | Methods and compositions related to IRM compounds and toll-like recptor pathways |
| DE10221836A1 (de) * | 2002-05-16 | 2003-12-04 | Lohmann Animal Health Gmbh | Attenuierung von Metapneumovirus |
| AU2003256823B9 (en) * | 2002-07-25 | 2009-01-08 | Medimmune, Llc | Methods of treating and preventing RSV, hMPV, and PIV using anti-RSV, anti-hMPV, and anti-PIV antibodies |
| JP2006517974A (ja) | 2003-02-13 | 2006-08-03 | スリーエム イノベイティブ プロパティズ カンパニー | Ｉｒｍ化合物およびトル様受容体８に関する方法および組成物 |
| US7563449B2 (en) | 2003-04-21 | 2009-07-21 | Pfizer Inc, | Methods for reducing cattle reproductive diseases |
| CN1813061B (zh) * | 2003-04-25 | 2013-05-29 | 免疫医疗有限责任公司 | 重组副流感病毒表达系统以及包含源自间质肺病毒的异种抗原的疫苗 |
| US7368537B2 (en) | 2003-07-15 | 2008-05-06 | Id Biomedical Corporation Of Quebec | Subunit vaccine against respiratory syncytial virus infection |
| EP1959011B1 (en) | 2003-10-24 | 2012-03-28 | Selexis S.A. | High efficiency gene transfer and expression in mammalian cells by a multiple transfection procedure of matrix attachment region sequences |
| FR2873378A1 (fr) | 2004-07-23 | 2006-01-27 | Pierre Fabre Medicament Sa | Complexes immunogenes, leur procede de preparation et leur utilisation dans des compositions pharmaceutiques |
| GB0422439D0 (en) | 2004-10-08 | 2004-11-10 | European Molecular Biology Lab Embl | Inhibitors of infection |
| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| WO2008114149A2 (en) * | 2007-03-21 | 2008-09-25 | Id Biomedical Corporation Of Quebec | Chimeric antigens |
| WO2008154456A2 (en) * | 2007-06-06 | 2008-12-18 | Nationwide Children's Hospital, Inc. | Methods and compositions relating to viral fusion proteins |
| ES2658347T3 (es) | 2007-08-13 | 2018-03-09 | Glaxosmithkline Biologicals Sa | Vacunas |
| JP5711972B2 (ja) | 2007-12-24 | 2015-05-07 | アイディー バイオメディカル コーポレイション オブ ケベック | 組換えｒｓｖ抗原 |
| PT2445526T (pt) * | 2009-06-24 | 2016-08-16 | Glaxosmithkline Biologicals Sa | Antigénios de rsv recombinantes |
-
2010
- 2010-06-24 SG SG2011091881A patent/SG176807A1/en unknown
- 2010-06-24 EP EP10728203A patent/EP2445527A2/en not_active Withdrawn
- 2010-06-24 JP JP2012516745A patent/JP5796011B2/ja active Active
- 2010-06-24 WO PCT/EP2010/059006 patent/WO2010149743A2/en not_active Ceased
- 2010-06-24 AU AU2010264686A patent/AU2010264686A1/en not_active Abandoned
- 2010-06-24 EA EA201270062A patent/EA201270062A1/ru unknown
- 2010-06-24 KR KR1020127001752A patent/KR20120093811A/ko not_active Withdrawn
- 2010-06-24 MX MX2012000036A patent/MX2012000036A/es not_active Application Discontinuation
- 2010-06-24 CN CN2010800374300A patent/CN102548578A/zh active Pending
- 2010-06-24 CA CA2766205A patent/CA2766205A1/en active Pending
- 2010-06-24 US US13/378,402 patent/US8889146B2/en active Active
-
2011
- 2011-12-13 ZA ZA2011/09164A patent/ZA201109164B/en unknown
- 2011-12-15 IL IL217008A patent/IL217008A0/en unknown