BR112018070323A2 - vacina contra rsv - Google Patents
vacina contra rsvInfo
- Publication number
- BR112018070323A2 BR112018070323A2 BR112018070323A BR112018070323A BR112018070323A2 BR 112018070323 A2 BR112018070323 A2 BR 112018070323A2 BR 112018070323 A BR112018070323 A BR 112018070323A BR 112018070323 A BR112018070323 A BR 112018070323A BR 112018070323 A2 BR112018070323 A2 BR 112018070323A2
- Authority
- BR
- Brazil
- Prior art keywords
- rsv
- nucleic acid
- acid molecules
- fusion
- fusion protein
- Prior art date
Links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10041—Use of virus, viral particle or viral elements as a vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18571—Demonstrated in vivo effect
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
a presente invenção se refere a novas moléculas de ácido nucléico que codificam uma proteína f pré-fusão de rsv ou sua parte imunologicamente ativa, em que a proteína f pré-fusão de rsv compreende a sequência de aminoácidos de seq id no: 1 ou 2. a invenção se refere ainda à utilização das moléculas de ácido nucleico ou vetores compreendendo as moléculas de ácido nucleico referidas, como uma vacina contra o vírus sincicial respiratório (rsv).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16163807 | 2016-04-05 | ||
PCT/EP2017/057957 WO2017174564A1 (en) | 2016-04-05 | 2017-04-04 | Vaccine against rsv |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112018070323A2 true BR112018070323A2 (pt) | 2019-01-29 |
Family
ID=55661317
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018070323A BR112018070323A2 (pt) | 2016-04-05 | 2017-04-04 | vacina contra rsv |
Country Status (18)
Country | Link |
---|---|
US (3) | US10729757B2 (pt) |
EP (1) | EP3439694A1 (pt) |
JP (2) | JP7233928B2 (pt) |
KR (3) | KR102401247B1 (pt) |
CN (1) | CN109069612A (pt) |
AU (1) | AU2017248018A1 (pt) |
BR (1) | BR112018070323A2 (pt) |
CA (1) | CA3018139A1 (pt) |
CL (1) | CL2018002825A1 (pt) |
EA (1) | EA201892250A1 (pt) |
IL (1) | IL262109B2 (pt) |
MA (1) | MA43762A (pt) |
MX (1) | MX2018012095A (pt) |
MY (1) | MY193584A (pt) |
PE (1) | PE20190433A1 (pt) |
PH (1) | PH12018501912A1 (pt) |
SG (1) | SG11201807912SA (pt) |
WO (1) | WO2017174564A1 (pt) |
Families Citing this family (21)
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EA039803B1 (ru) | 2013-04-25 | 2022-03-15 | Янссен Вэксинс Энд Превеншн Б.В. | Стабилизированные растворимые f-полипептиды rsv до слияния |
EA035909B1 (ru) | 2015-07-07 | 2020-08-31 | Янссен Вэксинс Энд Превеншн Б.В. | Стабилизированные растворимые f-полипептиды rsv до слияния |
PL3319633T3 (pl) | 2015-07-07 | 2021-04-19 | Janssen Vaccines & Prevention B.V. | Szczepionka przeciwko rsv |
HUE059127T2 (hu) | 2015-10-22 | 2022-10-28 | Modernatx Inc | Légúti vírusok elleni vakcinák |
EA201892250A1 (ru) * | 2016-04-05 | 2019-03-29 | Янссен Вэксинс Энд Превеншн Б.В. | Вакцина против rsv |
JP7088841B2 (ja) * | 2016-04-05 | 2022-06-21 | ヤンセン ファッシンズ アンド プリベンション ベーフェー | 安定化された可溶性融合前rsv fタンパク質 |
EP3464331B1 (en) | 2016-05-30 | 2020-10-28 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion rsv f proteins |
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EP3624844A1 (en) * | 2017-05-17 | 2020-03-25 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against rsv infection |
SG11202001458SA (en) * | 2017-09-15 | 2020-03-30 | Janssen Vaccines & Prevention Bv | Method for the safe induction of immunity against rsv |
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JP2022532723A (ja) | 2019-05-15 | 2022-07-19 | ヤンセン ファッシンズ アンド プリベンション ベーフェー | 季節性インフルエンザワクチン及びアデノウイルス系呼吸器合胞体ウイルスワクチンの共投与 |
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KR102401247B1 (ko) | 2022-05-25 |
CN109069612A (zh) | 2018-12-21 |
US10729757B2 (en) | 2020-08-04 |
IL262109B2 (en) | 2023-04-01 |
US20200360506A1 (en) | 2020-11-19 |
MY193584A (en) | 2022-10-19 |
MA43762A (fr) | 2021-04-21 |
SG11201807912SA (en) | 2018-10-30 |
PE20190433A1 (es) | 2019-03-21 |
IL262109A (en) | 2018-11-29 |
KR20180132761A (ko) | 2018-12-12 |
EP3439694A1 (en) | 2019-02-13 |
US20220288186A1 (en) | 2022-09-15 |
CA3018139A1 (en) | 2017-10-12 |
WO2017174564A1 (en) | 2017-10-12 |
JP2019510497A (ja) | 2019-04-18 |
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