KR20180084336A - 마우스에 대한 병원성이 증가된 인플루엔자 a 바이러스 - Google Patents

마우스에 대한 병원성이 증가된 인플루엔자 a 바이러스 Download PDF

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KR20180084336A
KR20180084336A KR1020170007302A KR20170007302A KR20180084336A KR 20180084336 A KR20180084336 A KR 20180084336A KR 1020170007302 A KR1020170007302 A KR 1020170007302A KR 20170007302 A KR20170007302 A KR 20170007302A KR 20180084336 A KR20180084336 A KR 20180084336A
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South Korea
Prior art keywords
influenza
virus
against mouse
increased pathogenicity
pathogenicity against
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KR1020170007302A
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KR102027636B1 (ko
Inventor
송민석
최영기
백윤희
최원석
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충북대학교 산학협력단
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/12—Animals modified by administration of exogenous cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0337—Animal models for infectious diseases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16121—Viruses as such, e.g. new isolates, mutants or their genomic sequences

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Husbandry (AREA)
  • Immunology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

본원은, 마우스에 대한 병원성이 증가된 인플루엔자 A 바이러스 및 이를 이용한 인플루엔자 A 바이러스 감염 모델 마우스의 제조방법에 관한 것이다.
KR1020170007302A 2017-01-16 2017-01-16 마우스에 대한 병원성이 증가된 인플루엔자 a 바이러스 KR102027636B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020170007302A KR102027636B1 (ko) 2017-01-16 2017-01-16 마우스에 대한 병원성이 증가된 인플루엔자 a 바이러스

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020170007302A KR102027636B1 (ko) 2017-01-16 2017-01-16 마우스에 대한 병원성이 증가된 인플루엔자 a 바이러스

Publications (2)

Publication Number Publication Date
KR20180084336A true KR20180084336A (ko) 2018-07-25
KR102027636B1 KR102027636B1 (ko) 2019-10-01

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KR1020170007302A KR102027636B1 (ko) 2017-01-16 2017-01-16 마우스에 대한 병원성이 증가된 인플루엔자 a 바이러스

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000253876A (ja) * 1999-03-08 2000-09-19 Dnavec Research Inc センダイウイルスベクターを用いたワクチンおよびワクチンタンパク質
JP2009268471A (ja) * 2009-08-07 2009-11-19 Dnavec Research Inc センダイウイルスベクターを用いたワクチンおよびワクチンタンパク質
JP2012191948A (ja) * 2012-07-04 2012-10-11 Dnavec Research Inc センダイウイルスベクターを用いたワクチンおよびワクチンタンパク質
KR101315273B1 (ko) * 2012-10-29 2013-10-08 대한민국 강독화된 인플루엔자 바이러스 변이주
KR101626798B1 (ko) 2013-09-26 2016-06-02 대한민국(농림축산식품부 농림축산검역본부장) 신규한 h3n2 혈청형의 인플루엔자 바이러스 및 이를 포함하는 백신 조성물

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000253876A (ja) * 1999-03-08 2000-09-19 Dnavec Research Inc センダイウイルスベクターを用いたワクチンおよびワクチンタンパク質
JP2009268471A (ja) * 2009-08-07 2009-11-19 Dnavec Research Inc センダイウイルスベクターを用いたワクチンおよびワクチンタンパク質
JP2012191948A (ja) * 2012-07-04 2012-10-11 Dnavec Research Inc センダイウイルスベクターを用いたワクチンおよびワクチンタンパク質
KR101315273B1 (ko) * 2012-10-29 2013-10-08 대한민국 강독화된 인플루엔자 바이러스 변이주
KR101626798B1 (ko) 2013-09-26 2016-06-02 대한민국(농림축산식품부 농림축산검역본부장) 신규한 h3n2 혈청형의 인플루엔자 바이러스 및 이를 포함하는 백신 조성물

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Rolling et al., Journal of Virology. 2009, Jul; 83(13): 6673-80

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