JP2015521467A5 - - Google Patents
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- JP2015521467A5 JP2015521467A5 JP2015517226A JP2015517226A JP2015521467A5 JP 2015521467 A5 JP2015521467 A5 JP 2015521467A5 JP 2015517226 A JP2015517226 A JP 2015517226A JP 2015517226 A JP2015517226 A JP 2015517226A JP 2015521467 A5 JP2015521467 A5 JP 2015521467A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- seq
- sequence represented
- amino acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 102000039446 nucleic acids Human genes 0.000 claims description 29
- 108020004707 nucleic acids Proteins 0.000 claims description 29
- 150000007523 nucleic acids Chemical class 0.000 claims description 29
- 102000004169 proteins and genes Human genes 0.000 claims description 5
- 108090000623 proteins and genes Proteins 0.000 claims description 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 36
- 150000001413 amino acids Chemical class 0.000 claims 18
- 108020001507 fusion proteins Proteins 0.000 claims 8
- 102000037865 fusion proteins Human genes 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 230000007115 recruitment Effects 0.000 claims 3
- 108700001237 Nucleic Acid-Based Vaccines Proteins 0.000 claims 2
- 229940023146 nucleic acid vaccine Drugs 0.000 claims 2
- 208000035285 Allergic Seasonal Rhinitis Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 239000013566 allergen Substances 0.000 description 15
- 238000000034 method Methods 0.000 description 9
- 108010064171 Lysosome-Associated Membrane Glycoproteins Proteins 0.000 description 3
- 102000014944 Lysosome-Associated Membrane Glycoproteins Human genes 0.000 description 3
- 230000000172 allergic effect Effects 0.000 description 3
- 208000010668 atopic eczema Diseases 0.000 description 3
- 210000003463 organelle Anatomy 0.000 description 3
- 108090000765 processed proteins & peptides Proteins 0.000 description 3
- 102000004196 processed proteins & peptides Human genes 0.000 description 3
- 108010041986 DNA Vaccines Proteins 0.000 description 2
- 229940021995 DNA vaccine Drugs 0.000 description 2
- 108010009489 Lysosomal-Associated Membrane Protein 3 Proteins 0.000 description 2
- 102100038213 Lysosome-associated membrane glycoprotein 3 Human genes 0.000 description 2
- 108010076504 Protein Sorting Signals Proteins 0.000 description 2
- 230000002009 allergenic effect Effects 0.000 description 2
- 208000026935 allergic disease Diseases 0.000 description 2
- 210000000612 antigen-presenting cell Anatomy 0.000 description 2
- 230000028993 immune response Effects 0.000 description 2
- 229920001184 polypeptide Polymers 0.000 description 2
- 230000006641 stabilisation Effects 0.000 description 2
- 238000011105 stabilization Methods 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 101000883874 Cryptomeria japonica Endochitinase 4 Proteins 0.000 description 1
- 108010029862 Endolyn Proteins 0.000 description 1
- 102000049978 Endolyn Human genes 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 108010009491 Lysosomal-Associated Membrane Protein 2 Proteins 0.000 description 1
- 102000009565 Lysosomal-Associated Membrane Protein 2 Human genes 0.000 description 1
- 102100020983 Lysosome membrane protein 2 Human genes 0.000 description 1
- 101710165448 Lysosome membrane protein 2 Proteins 0.000 description 1
- 108091005461 Nucleic proteins Proteins 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000002865 immune cell Anatomy 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000002132 lysosomal effect Effects 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2012/042552 WO2013187906A1 (en) | 2012-06-15 | 2012-06-15 | Nucleic acids for treatment of allergies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015119893A Division JP6088584B2 (ja) | 2015-06-15 | 2015-06-15 | アレルギー治療のための核酸 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015521467A JP2015521467A (ja) | 2015-07-30 |
| JP2015521467A5 true JP2015521467A5 (enExample) | 2015-09-10 |
| JP5807994B2 JP5807994B2 (ja) | 2015-11-10 |
Family
ID=49758576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015517226A Active JP5807994B2 (ja) | 2012-06-15 | 2012-06-15 | アレルギー治療のための核酸 |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US9744230B2 (enExample) |
| EP (2) | EP3808361A1 (enExample) |
| JP (1) | JP5807994B2 (enExample) |
| KR (2) | KR102386481B1 (enExample) |
| CN (2) | CN107937423A (enExample) |
| AU (3) | AU2012382406B2 (enExample) |
| BR (1) | BR112014031327B1 (enExample) |
| CA (1) | CA2876824C (enExample) |
| CY (1) | CY1123769T1 (enExample) |
| DK (1) | DK2861240T3 (enExample) |
| ES (1) | ES2831723T3 (enExample) |
| HR (1) | HRP20201815T1 (enExample) |
| HU (1) | HUE052481T2 (enExample) |
| IL (4) | IL236174B (enExample) |
| LT (1) | LT2861240T (enExample) |
| PL (1) | PL2861240T3 (enExample) |
| PT (1) | PT2861240T (enExample) |
| RS (1) | RS61098B1 (enExample) |
| SI (1) | SI2861240T1 (enExample) |
| WO (1) | WO2013187906A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160185831A1 (en) * | 2011-06-14 | 2016-06-30 | Immunomic Therapeutics, Inc. | Nucleic acids for treatment of allergies |
| HUE052481T2 (hu) | 2012-06-15 | 2021-04-28 | Immunomic Therapeutics Inc | Nukleinsavak, allergiák kezelésére |
| DK2914286T3 (da) | 2012-10-30 | 2021-11-08 | Aravax Pty Ltd | Hidtil ukendte immunterapeutiske molekyler og anvendelser deraf |
| KR20160075532A (ko) | 2013-09-25 | 2016-06-29 | 아라백스 피티와이 엘티디 | 신규한 면역치료제 조성물 및 이의 용도 |
| CN106459994A (zh) * | 2014-06-23 | 2017-02-22 | 免疫治疗有限公司 | 用于治疗花生过敏的核酸 |
| US10149904B2 (en) | 2015-02-20 | 2018-12-11 | The Board Of Trusteees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| US11452774B2 (en) | 2015-02-20 | 2022-09-27 | The Board Of Trustees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| US10166286B2 (en) | 2015-02-20 | 2019-01-01 | The Board Of Trustees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| US10143742B2 (en) | 2015-02-20 | 2018-12-04 | The Board Of Trustees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| JP6697562B2 (ja) | 2015-12-23 | 2020-05-20 | メディジーン イミュノテラピーズ ゲーエムベーハー | 樹状細胞組成物 |
| US11826423B2 (en) | 2016-11-16 | 2023-11-28 | Immunomic Therapeutics, Inc. | Nucleic acids for treatment of allergies |
| WO2018195527A1 (en) * | 2017-04-22 | 2018-10-25 | Immunomic Therapeutics, Inc. | Improved lamp constructs |
| KR20200016224A (ko) * | 2017-05-02 | 2020-02-14 | 이뮤노믹 쎄라퓨틱스, 인크. | 암 항원을 포함하는 lamp (리소솜 연관 막 단백질) 구축물 |
| US11382934B2 (en) | 2017-07-18 | 2022-07-12 | Before Brands, Inc. | Methods for making mixed allergen compositions |
| WO2019194656A1 (ko) * | 2018-04-06 | 2019-10-10 | (주)에스엘에스바이오 | 신규한 면역글로불린 e의 에피토프, 그와 결합하는 항체 및 상기 항체를 포함하는 시료 중 면역글로불린 e를 분석하기 위한 키트 |
| CA3099495A1 (en) * | 2018-05-11 | 2019-11-14 | Astellas Pharma Inc. | Nucleic acid for treating mite allergy |
| WO2019216396A1 (ja) * | 2018-05-11 | 2019-11-14 | アステラス製薬株式会社 | 甲殻類アレルギー治療のための核酸 |
| US12398195B2 (en) | 2018-05-15 | 2025-08-26 | Immunomic Therapeutics, Inc. | Lamp constructs comprising allergens |
| CA3127337A1 (en) | 2019-01-23 | 2020-07-30 | Before Brands, Inc. | Methods for making mixed allergen compositions |
| JP7266700B2 (ja) * | 2019-03-13 | 2023-04-28 | プソマーゲン， インコーポレイテッド | アレルギー治療のためのエピトープベースアプローチ及びクローン病のための阻害薬 |
| EP4333807A1 (en) * | 2021-05-04 | 2024-03-13 | Sovida Solutions Ltd. | Nicotinamide adenine dinucleotide (nad) compositions, methods of manufacturing thereof, and methods of use thereof |
| AU2022321126A1 (en) * | 2021-08-06 | 2024-02-29 | Kao Corporation | Nucleic acid structure utilizing snare |
| FI20237105A1 (en) | 2023-05-29 | 2024-11-30 | Onni Biotechnologies Oy | Modified natural killer cells with enhanced cytotoxic action and greater survival |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD335810S (en) | 1990-07-02 | 1993-05-25 | Dick-Ming Asien | Handle for luggage or similar article |
| US6090386A (en) | 1991-07-12 | 2000-07-18 | Griffith; Irwin J. | T cell peptides of the CRX JII allergen |
| US6982326B1 (en) | 1991-07-12 | 2006-01-03 | Immulogic Pharmaceutical Corporation | Allergenic proteins and peptides from Japanese cedar pollen |
| WO1994024281A1 (en) * | 1993-04-14 | 1994-10-27 | Immulogic Pharmaceutical Corporation | T cell epitopes of the major allergens from dermatophagoides (house dust mite) |
| AU5668194A (en) * | 1992-11-12 | 1994-06-08 | Immulogic Pharmaceutical Corporation | Allergenic proteins and peptides from japanese cedar pollen |
| US5633234A (en) | 1993-01-22 | 1997-05-27 | The Johns Hopkins University | Lysosomal targeting of immunogens |
| JP3649460B2 (ja) | 1993-11-05 | 2005-05-18 | 明治乳業株式会社 | スギ花粉アレルゲンＣｒｙ ｊ ＩＩエピトープ |
| GB9516760D0 (en) | 1995-08-16 | 1995-10-18 | Sandoz Ltd | Organic compounds |
| JPH11507840A (ja) | 1995-12-29 | 1999-07-13 | ユニバーシティ オブ アーカンソー | ピーナッツアレルゲンおよび方法 |
| DE69737659T2 (de) | 1996-06-14 | 2007-12-27 | Meiji Dairies Corp. | Peptide aus t-zellepitopen |
| EP1278550A4 (en) * | 2000-04-07 | 2004-05-12 | Univ California | SYNERGISTIC IMPROVEMENTS OF POLYNUCLEOTIDE VACCINE |
| WO2002074250A2 (en) | 2001-03-16 | 2002-09-26 | Panacea Pharmaceuticals | Methods and reagents for decreasing clinical reaction to allergy |
| ES2404689T3 (es) | 2001-04-05 | 2013-05-28 | The Johns Hopkins University | Vacunas quiméricas que comprenden el dominio lumenal de LAMP-1 o LAMP-2 |
| US20060003148A1 (en) | 2004-06-30 | 2006-01-05 | Zwynenburg James L | Interlocking polymeric foam floor underlayment and process for making |
| WO2006099574A2 (en) * | 2005-03-16 | 2006-09-21 | Tai June Yoo | Cockroach allergen gene expression and delivery systems and uses |
| US20090304738A1 (en) | 2005-06-16 | 2009-12-10 | Moran Thomas M | Methods for Enhancing Immune Responses |
| US7566456B2 (en) | 2005-06-23 | 2009-07-28 | Haiming Chen | Allergen vaccine proteins for the treatment and prevention of allergic diseases |
| JPWO2007024026A1 (ja) * | 2005-08-25 | 2009-03-05 | 明石 満 | Ｔ細胞認識エピトープペプチドを固定化又は内包化した生分解性ナノ粒子 |
| US20080006554A1 (en) | 2006-07-07 | 2008-01-10 | Medtronic Vascular, Inc. | Packaging assembly for a catheter |
| EP2042193A1 (en) * | 2007-09-28 | 2009-04-01 | Biomay AG | RNA Vaccines |
| WO2010029317A2 (en) * | 2008-09-10 | 2010-03-18 | Ibd Column Therapies International Ab | Treating inflammatory conditions |
| HUE052481T2 (hu) | 2012-06-15 | 2021-04-28 | Immunomic Therapeutics Inc | Nukleinsavak, allergiák kezelésére |
| US11826423B2 (en) * | 2016-11-16 | 2023-11-28 | Immunomic Therapeutics, Inc. | Nucleic acids for treatment of allergies |
| WO2018195527A1 (en) * | 2017-04-22 | 2018-10-25 | Immunomic Therapeutics, Inc. | Improved lamp constructs |
-
2012
- 2012-06-15 HU HUE12878776A patent/HUE052481T2/hu unknown
- 2012-06-15 AU AU2012382406A patent/AU2012382406B2/en active Active
- 2012-06-15 CN CN201710999629.5A patent/CN107937423A/zh active Pending
- 2012-06-15 CN CN201280075163.5A patent/CN104519896B/zh active Active
- 2012-06-15 SI SI201231855T patent/SI2861240T1/sl unknown
- 2012-06-15 EP EP20194785.0A patent/EP3808361A1/en not_active Withdrawn
- 2012-06-15 DK DK12878776.9T patent/DK2861240T3/da active
- 2012-06-15 KR KR1020207012427A patent/KR102386481B1/ko active Active
- 2012-06-15 RS RS20201379A patent/RS61098B1/sr unknown
- 2012-06-15 ES ES12878776T patent/ES2831723T3/es active Active
- 2012-06-15 EP EP12878776.9A patent/EP2861240B1/en active Active
- 2012-06-15 HR HRP20201815TT patent/HRP20201815T1/hr unknown
- 2012-06-15 PL PL12878776T patent/PL2861240T3/pl unknown
- 2012-06-15 LT LTEP12878776.9T patent/LT2861240T/lt unknown
- 2012-06-15 CA CA2876824A patent/CA2876824C/en active Active
- 2012-06-15 JP JP2015517226A patent/JP5807994B2/ja active Active
- 2012-06-15 BR BR112014031327-0A patent/BR112014031327B1/pt active IP Right Grant
- 2012-06-15 WO PCT/US2012/042552 patent/WO2013187906A1/en not_active Ceased
- 2012-06-15 KR KR1020157000696A patent/KR102107646B1/ko active Active
- 2012-06-15 PT PT128787769T patent/PT2861240T/pt unknown
-
2014
- 2014-12-11 IL IL23617414A patent/IL236174B/en active IP Right Grant
-
2016
- 2016-03-02 US US15/058,224 patent/US9744230B2/en active Active
-
2017
- 2017-07-31 US US15/663,871 patent/US10072053B2/en active Active
-
2018
- 2018-01-25 AU AU2018200625A patent/AU2018200625B2/en active Active
-
2019
- 2019-10-18 AU AU2019250227A patent/AU2019250227B2/en active Active
- 2019-10-29 IL IL270260A patent/IL270260B/en active IP Right Grant
- 2019-10-29 IL IL270262A patent/IL270262A/en unknown
- 2019-10-29 IL IL270261A patent/IL270261B/en active IP Right Grant
-
2020
- 2020-09-22 US US17/028,762 patent/US20220081474A1/en active Pending
- 2020-11-23 CY CY20201101107T patent/CY1123769T1/el unknown
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