|
US3378587A
(en)
|
1963-03-14 |
1968-04-16 |
Du Pont |
3, 3'-diaminomethyl-1, 1'-biadamantane
|
|
NL127995C
(cg-RX-API-DMAC7.html)
|
1963-12-20 |
|
Geigy Ag J R |
|
|
US3341538A
(en)
|
1965-06-18 |
1967-09-12 |
Geigy Chem Corp |
Certain 2, 6-methano-3-benzazocines
|
|
DE2108954A1
(en)
|
1971-02-25 |
1972-09-07 |
Boehringer Sohn Ingelheim |
2-(furylmethyl)-6,7-benzomorphans - useful as cns active agents
|
|
DE1801556A1
(de)
|
1968-10-05 |
1970-05-21 |
Huels Chemische Werke Ag |
Verfahren zur Herstellung von substituierten Hexahydropyrimidinonen-(2)
|
|
GB1304175A
(cg-RX-API-DMAC7.html)
|
1969-03-31 |
1973-01-24 |
|
|
|
DE2105743C3
(de)
|
1971-02-08 |
1979-11-29 |
Boehringer Sohn Ingelheim |
2-(Furylmethyl)- a -5,9-dialkyl -6,7benzomorphane, Verfahren zu ihrer Herstellung und deren Verwendung
|
|
US3681349A
(en)
|
1970-03-05 |
1972-08-01 |
Morton Norwich Products Inc |
1-(substituted benzyl) tetrahydro-2-(1h) pyrimidones
|
|
US4043927A
(en)
|
1972-03-07 |
1977-08-23 |
Sun Ventures, Inc. |
Friction or tractive drive containing ethers of adamantanes
|
|
DE2229695A1
(de)
|
1972-06-19 |
1974-01-31 |
Boehringer Sohn Ingelheim |
2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung
|
|
DE2338369A1
(de)
|
1973-07-26 |
1975-02-13 |
Schering Ag |
Mikrobiologische hydroxylierung von 2,6-methano-3-benzazocinen
|
|
SU511005A3
(ru)
|
1973-10-27 |
1976-04-15 |
К.Х.Берингер Зон., (Фирма) |
Способ получени (метоксиметилфурилметил)6,7-бензоморфанов или морфинанов
|
|
US4009171A
(en)
|
1974-02-21 |
1977-02-22 |
Sterling Drug Inc. |
N-acylated-11-oxygenated-2,6-methano-3-benzazocine intermediates
|
|
DE2411382C3
(de)
|
1974-03-09 |
1979-09-06 |
C.H. Boehringer Sohn, 6507 Ingelheim |
2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung
|
|
US4136145A
(en)
|
1974-07-05 |
1979-01-23 |
Schering Aktiengesellschaft |
Medicament carriers in the form of film having active substance incorporated therein
|
|
US4136162A
(en)
|
1974-07-05 |
1979-01-23 |
Schering Aktiengesellschaft |
Medicament carriers in the form of film having active substance incorporated therein
|
|
DE2437610A1
(de)
|
1974-08-05 |
1976-02-26 |
Boehringer Sohn Ingelheim |
Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung
|
|
GB1513961A
(en)
|
1975-02-25 |
1978-06-14 |
Acf Chemiefarma Nv |
6,7-benzomorphans method for their preparation and intermediates
|
|
US4108857A
(en)
|
1975-08-18 |
1978-08-22 |
Sterling Drug Inc. |
Imidazolylmethyl methanobenzazocines
|
|
DE2828039A1
(de)
|
1978-06-26 |
1980-01-10 |
Boehringer Sohn Ingelheim |
2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
|
|
US5393735A
(en)
|
1990-08-09 |
1995-02-28 |
Rohm And Haas Company |
Herbicidal glutarimides
|
|
CA2023492A1
(en)
|
1989-08-31 |
1991-03-01 |
Barry Clifford Lange |
Herbicidal glutarimides
|
|
US5098916A
(en)
|
1990-03-29 |
1992-03-24 |
G. D. Searle & Co. |
Propanobicyclic amine derivatives for cns disorders
|
|
EP0454444A1
(en)
|
1990-04-24 |
1991-10-30 |
Nissan Chemical Industries Ltd. |
Glutarimide derivatives and herbicides
|
|
US5215992A
(en)
|
1990-04-30 |
1993-06-01 |
G. D. Searle & Co. |
Ethanobicyclic amine derivatives for CNS disorders
|
|
US5089506A
(en)
|
1990-04-30 |
1992-02-18 |
G. D. Searle & Co. |
Ethanobicyclic amine derivatives for cns disorders
|
|
DK204291D0
(da)
|
1991-12-20 |
1991-12-20 |
Novo Nordisk As |
Heterocykliske forbindelser deres fremstilling og anvendelse
|
|
CA2049244A1
(en)
|
1990-08-16 |
1992-02-17 |
Steven H. Christiansen |
Process for absorption of sulfur compounds from fluids using heterocyclic compounds having at least one ring nitrogen atom
|
|
AU646519B2
(en)
|
1990-10-10 |
1994-02-24 |
Schering Corporation |
Pyridine and pyridine N-oxide derivatives of diaryl methyl piperidines or piperazines, and compositions and methods of use thereof
|
|
GB9023583D0
(en)
|
1990-10-30 |
1990-12-12 |
Beecham Group Plc |
Novel compounds
|
|
RU2131420C1
(ru)
|
1991-10-11 |
1999-06-10 |
Дзе Дюпон Мерк Фармасьютикал Компани |
Циклические мочевины, способ ингибирования роста ретровирусов и фармацевтическая композиция
|
|
US5610294A
(en)
|
1991-10-11 |
1997-03-11 |
The Du Pont Merck Pharmaceutical Company |
Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors
|
|
DE69329106T2
(de)
|
1992-04-30 |
2001-03-22 |
Taiho Pharmaceutical Co., Ltd. |
Oxazolidinderivat und sein pharmazeutisch verträgliches salz
|
|
JPH0753721B2
(ja)
|
1992-09-11 |
1995-06-07 |
工業技術院長 |
環状ウレタン化合物の製造法
|
|
GB9225377D0
(en)
|
1992-12-04 |
1993-01-27 |
Ici Plc |
Herbicides
|
|
US5521202A
(en)
|
1993-04-07 |
1996-05-28 |
Taiho Pharmaceutical Co., Ltd. |
Thiazolidine derivatives and pharmaceutical compositions containing the same
|
|
TW280812B
(cg-RX-API-DMAC7.html)
|
1993-07-02 |
1996-07-11 |
Bayer Ag |
|
|
EP0640594A1
(en)
|
1993-08-23 |
1995-03-01 |
Fujirebio Inc. |
Hydantoin derivative as metalloprotease inhibitor
|
|
JPH07157681A
(ja)
|
1993-12-08 |
1995-06-20 |
Konica Corp |
有機顔料の製造方法及び有機顔料を含有する電子写真感光体
|
|
DE19500118A1
(de)
|
1994-05-18 |
1995-11-23 |
Bayer Ag |
Substituierte Diazacyclohexandi(thi)one
|
|
JP3948744B2
(ja)
|
1994-11-04 |
2007-07-25 |
大日本住友製薬株式会社 |
新規なラクタム誘導体
|
|
US5780466A
(en)
|
1995-01-30 |
1998-07-14 |
Sanofi |
Substituted heterocyclic compounds method of preparing them and pharmaceutical compositions in which they are present
|
|
FR2729954B1
(fr)
|
1995-01-30 |
1997-08-01 |
Sanofi Sa |
Composes heterocycliques substitues, procede pour leur preparation et compositions pharmaceutiques les contenant
|
|
GB9510459D0
(en)
|
1995-05-24 |
1995-07-19 |
Zeneca Ltd |
Bicyclic amines
|
|
US5776959A
(en)
|
1995-06-05 |
1998-07-07 |
Washington University |
Anticonvulsant and anxiolytic lactam and thiolactam derivatives
|
|
GB9517622D0
(en)
|
1995-08-29 |
1995-11-01 |
Univ Edinburgh |
Regulation of intracellular glucocorticoid concentrations
|
|
JPH09151179A
(ja)
|
1995-11-30 |
1997-06-10 |
Canon Inc |
光学活性化合物、これを含む液晶組成物、それを有する液晶素子、それらを用いた液晶装置及び表示方法
|
|
WO1997036605A1
(en)
|
1996-04-03 |
1997-10-09 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
|
CA2262502C
(en)
|
1996-07-31 |
2002-11-26 |
Nikken Chemicals Co., Ltd. |
6-phenyltetrahydro-1,3-oxazin-2-one derivatives and pharmaceutical composition containing the same
|
|
US5866702A
(en)
|
1996-08-02 |
1999-02-02 |
Cv Therapeutics, Incorporation |
Purine inhibitors of cyclin dependent kinase 2
|
|
US6794390B2
(en)
|
1996-08-02 |
2004-09-21 |
Cv Therapeutics, Inc. |
Purine inhibitors of cyclin dependent kinase 2 & ikappabalpha
|
|
GB9623944D0
(en)
|
1996-11-15 |
1997-01-08 |
Zeneca Ltd |
Bicyclic amine derivatives
|
|
US6159990A
(en)
|
1997-06-18 |
2000-12-12 |
Synaptic Pharmaceutical Corporation |
Oxazolidinones as α1A receptor antagonists
|
|
CA2294549A1
(en)
|
1997-06-18 |
1998-12-23 |
Synaptic Pharmaceutical Corporation |
Heterocyclic substituted piperidines and uses thereof
|
|
DE19731784A1
(de)
|
1997-07-24 |
1999-02-04 |
Bayer Ag |
Substituierte N-Aryl-N-thioxocarbonyl-sulfonamide
|
|
GB9715892D0
(en)
|
1997-07-29 |
1997-10-01 |
Zeneca Ltd |
Heterocyclic compounds
|
|
US5936124A
(en)
|
1998-06-22 |
1999-08-10 |
Sepacor Inc. |
Fluoxetine process from benzoylpropionic acid
|
|
US7410995B1
(en)
|
1998-08-14 |
2008-08-12 |
Gpi Nil Holdings Inc. |
N-linked sulfonamide of heterocyclic thioesters for vision and memory disorders
|
|
DE19918725A1
(de)
|
1999-04-24 |
2000-10-26 |
Bayer Ag |
Substituierte N-Cyano-sulfonsäureanilide
|
|
DE19929348A1
(de)
|
1999-06-26 |
2000-12-28 |
Bayer Ag |
Verfahren zur Herstellung von 2-Heterocyclylmethyl-benzoesäurederivaten
|
|
US7256005B2
(en)
|
1999-08-10 |
2007-08-14 |
The Chancellor, Masters And Scholars Of The University Of Oxford |
Methods for identifying iminosugar derivatives that inhibit HCV p7 ion channel activity
|
|
CA2393672A1
(en)
|
1999-12-17 |
2001-06-21 |
Schering Corporation |
Selective neurokinin antagonists
|
|
US6436928B1
(en)
|
1999-12-17 |
2002-08-20 |
Schering Corporation |
Selective neurokinin antagonists
|
|
WO2001055063A1
(en)
|
2000-01-25 |
2001-08-02 |
Idemitsu Petrochemical Co., Ltd. |
Novel bisadamantane compounds, process for preparing the same, and novel biadamantane derivatives
|
|
GB0003397D0
(en)
|
2000-02-14 |
2000-04-05 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
DE10034623A1
(de)
|
2000-07-17 |
2002-01-31 |
Bayer Ag |
Heterocyclisch substituierte Pyridine als Cytokin-Inhibitoren
|
|
DE10034800A1
(de)
|
2000-07-18 |
2002-01-31 |
Bayer Ag |
Substituierte Benzostickstoffheterocyclen
|
|
DE10034803A1
(de)
|
2000-07-18 |
2002-01-31 |
Bayer Ag |
Substituierte Sulfonsäureanilide
|
|
DE10035927A1
(de)
|
2000-07-21 |
2002-03-07 |
Asta Medica Ag |
Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
|
|
DE10035928A1
(de)
|
2000-07-21 |
2002-03-07 |
Asta Medica Ag |
Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
|
|
DE10035908A1
(de)
|
2000-07-21 |
2002-03-07 |
Asta Medica Ag |
Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
|
|
BR0113300A
(pt)
|
2000-08-16 |
2004-01-13 |
Neurogen Corp |
Composto ou um sal deste farmaceuticamente aceitável, composição farmacêutica, método para o tratamento de uma doença ou distúrbio associados com o agonismo patogênico, agonismo inverso ou antagonismo do receptor de gabaa, uso de um composto ou um sal, é, métodos para localização dos receptores de gabaa em uma amostra de tecido, de inibição da ligação de um composto de benzodiazepina a um receptor de gabaa, e para a alteração da atividade de transdutora de sinal dos receptores de gabaa
|
|
US7294637B2
(en)
|
2000-09-11 |
2007-11-13 |
Sepracor, Inc. |
Method of treating addiction or dependence using a ligand for a monamine receptor or transporter
|
|
WO2002022572A2
(en)
|
2000-09-11 |
2002-03-21 |
Sepracor, Inc. |
Ligands for monoamine receptors and transporters, and methods of use thereof (neurotransmission)
|
|
JP2002179572A
(ja)
|
2000-10-06 |
2002-06-26 |
Nikken Chem Co Ltd |
アレルギー性眼疾患治療剤
|
|
US6841671B2
(en)
|
2000-10-26 |
2005-01-11 |
Pfizer Inc. |
Spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors
|
|
US20030143668A1
(en)
|
2001-06-18 |
2003-07-31 |
National Institute Of Advanced Industrial |
Guanosine triphosphate-binding protein coupled receptors
|
|
JP3873115B2
(ja)
|
2001-09-25 |
2007-01-24 |
独立行政法人産業技術総合研究所 |
環状ウレタン製造方法
|
|
AR037243A1
(es)
|
2001-10-15 |
2004-11-03 |
Schering Corp |
Antagonistas del receptor de adenosina a2a,a5-amino-imidazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]pirimidina, composiciones farmaceuticas y el uso de dichos compuestos para la preparacion de un medicamento
|
|
WO2003043988A1
(en)
|
2001-11-22 |
2003-05-30 |
Ono Pharmaceutical Co., Ltd. |
Piperidin-2-one derivative compounds and drugs containing these compounds as the active ingredient
|
|
CA2471880A1
(en)
|
2001-12-28 |
2003-07-17 |
Bayer Pharmaceuticals Corporation |
1h-pyrazolyl derivative compounds, for use in diseases associated with the 5-ht2c receptor
|
|
JP2003300884A
(ja)
*
|
2002-04-08 |
2003-10-21 |
Nikken Chem Co Ltd |
TNF−α産生阻害剤
|
|
ATE308544T1
(de)
|
2002-04-26 |
2005-11-15 |
Pfizer Prod Inc |
N-substituiete heteroaryloxy-aryl-spiro- pyrimidine-2,4,6-trion metalloproteinase inhibitoren
|
|
EP1501834B1
(en)
|
2002-04-26 |
2005-09-07 |
Pfizer Products Inc. |
Triaryl-oxy-aryl-spiro-pyrimidine-2, 4, 6-trione metalloproteinase inhibitors
|
|
DE60335359D1
(de)
|
2002-04-30 |
2011-01-27 |
Kudos Pharm Ltd |
Phthalazinonderivate
|
|
MXPA04011327A
(es)
|
2002-05-17 |
2005-08-15 |
Jenken Biosciences Inc |
Opioides y compuestos similares a opioides y usos de los mismos.
|
|
ATE358482T1
(de)
|
2002-07-03 |
2007-04-15 |
Schering Corp |
1-amido-4-phenyl-4-benzyloxymethyl-piperidin derivative und verwandte verbindungen als neurokinin-1 (nk-1) antagonsisten zur behandlung von erbrechen, depressionen, angstzustände und husten
|
|
WO2004009559A2
(en)
|
2002-07-18 |
2004-01-29 |
Queen's University At Kingston |
Dihydrouracil compounds as anti-ictogenic or anti-epileptogenic agents
|
|
GB0218630D0
(en)
|
2002-08-10 |
2002-09-18 |
Tanabe Seiyaku Co |
Novel compounds
|
|
AR041198A1
(es)
|
2002-10-11 |
2005-05-04 |
Otsuka Pharma Co Ltd |
Compuesto 2,3-dihidro-6-nitroimidazo[2,1-b] oxaxol, y composiciones farmaceuticas que lo contienen
|
|
WO2004046137A1
(en)
|
2002-11-21 |
2004-06-03 |
Vicore Pharma Ab |
New tricyclic angiotensin ii agonists
|
|
GB0228410D0
(en)
|
2002-12-05 |
2003-01-08 |
Glaxo Group Ltd |
Novel Compounds
|
|
AU2003299612A1
(en)
|
2002-12-13 |
2004-07-09 |
Cytokinetics |
Compounds, compositions and methods
|
|
WO2004056744A1
(en)
|
2002-12-23 |
2004-07-08 |
Janssen Pharmaceutica N.V. |
Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors
|
|
US7276520B2
(en)
|
2003-03-26 |
2007-10-02 |
Merck & Co., Inc. |
Bicyclic piperidine derivatives as melanocortin-4 receptor agonists
|
|
JP4629657B2
(ja)
|
2003-04-11 |
2011-02-09 |
ハイ・ポイント・ファーマスーティカルズ、エルエルシー |
11β−ヒドロキシステロイドデヒドロゲナーゼ1型化活性化合物
|
|
US7700583B2
(en)
|
2003-04-11 |
2010-04-20 |
High Point Pharmaceuticals, Llc |
11β-hydroxysteroid dehydrogenase type 1 active compounds
|
|
US7696198B2
(en)
|
2003-04-16 |
2010-04-13 |
Memory Pharmaceuticals Corporation |
Phosphodiesterase 4 inhibitors
|
|
ITMI20031292A1
(it)
|
2003-06-25 |
2004-12-26 |
Nikem Research Srl |
Derivati biciclici nk-2 antagonisti selettivi.
|
|
DE10358004A1
(de)
|
2003-12-11 |
2005-07-14 |
Abbott Gmbh & Co. Kg |
Ketolactam-Verbindungen und ihre Verwendung
|
|
US7186844B2
(en)
|
2004-01-13 |
2007-03-06 |
Mitsubishi Gas Chemical Co., Inc. |
Method for producing cyclic carbamate ester
|
|
JP4324669B2
(ja)
|
2004-01-21 |
2009-09-02 |
独立行政法人産業技術総合研究所 |
環状ウレタンの製造方法
|
|
JP2005239670A
(ja)
|
2004-02-27 |
2005-09-08 |
Ono Pharmaceut Co Ltd |
含窒素複素環化合物およびその医薬用途
|
|
WO2005086700A2
(en)
|
2004-03-09 |
2005-09-22 |
Merck & Co., Inc. |
Hiv integrase inhibitors
|
|
US8519158B2
(en)
|
2004-03-12 |
2013-08-27 |
Ligand Pharmaceuticals Incorporated |
Androgen receptor modulator compounds and methods
|
|
JP2005272321A
(ja)
|
2004-03-23 |
2005-10-06 |
Ono Pharmaceut Co Ltd |
含窒素複素環化合物およびその医薬用途
|
|
US9012494B2
(en)
|
2004-05-07 |
2015-04-21 |
Janssen Pharmaceutica N.V. |
Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
|
|
EP1747198B1
(en)
|
2004-05-07 |
2008-06-04 |
Janssen Pharmaceutica N.V. |
Adamantyl pyrrolidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
|
|
GB0411404D0
(en)
|
2004-05-21 |
2004-06-23 |
Glaxo Group Ltd |
Novel compounds
|
|
GEP20094666B
(en)
|
2004-05-24 |
2009-04-10 |
Biovitrum Ab |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
|
|
MXPA06014572A
(es)
|
2004-06-24 |
2007-03-12 |
Incyte Corp |
Compuestos amido y su uso como farmaceuticos.
|
|
GB0414438D0
(en)
|
2004-06-28 |
2004-07-28 |
Syngenta Participations Ag |
Chemical compounds
|
|
DOP2005000123A
(es)
|
2004-07-02 |
2011-07-15 |
Merck Sharp & Dohme |
Inhibidores de cetp
|
|
EP1621536A1
(en)
|
2004-07-27 |
2006-02-01 |
Aventis Pharma S.A. |
Amino cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
|
|
EP1621539A1
(en)
|
2004-07-27 |
2006-02-01 |
Aventis Pharma S.A. |
Heterocycle -substituted cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
|
|
EP1621535A1
(en)
|
2004-07-27 |
2006-02-01 |
Aventis Pharma S.A. |
Substituted cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
|
|
WO2006017443A2
(en)
|
2004-08-02 |
2006-02-16 |
Osi Pharmaceuticals, Inc. |
Aryl-amino substituted pyrrolopyrimidine multi-kinase inhibiting compounds
|
|
CN101217958A
(zh)
|
2004-08-23 |
2008-07-09 |
默克公司 |
Akt活性抑制剂
|
|
EP1796657B1
(en)
|
2004-08-30 |
2009-12-23 |
Janssen Pharmaceutica N.V. |
N-2 adamantanyl-2-phenoxy-acetamide derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
|
|
CA2576850C
(en)
|
2004-08-30 |
2013-06-25 |
Janssen Pharmaceutica N.V. |
Tricyclic lactam derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
|
|
CN101056862B
(zh)
|
2004-09-10 |
2013-03-13 |
詹森药业有限公司 |
作为选择性雄激素受体调节剂(sarms)的咪唑烷-2-酮衍生物
|
|
JP2008515956A
(ja)
|
2004-10-12 |
2008-05-15 |
ノボ ノルディスク アクティーゼルスカブ |
11β−ヒドロキシステロイドデヒドロゲナーゼ1型活性スピロ化合物
|
|
EP1809626A2
(en)
|
2004-10-13 |
2007-07-25 |
Neurogen Corporation |
Aryl substituted 8-azabicyclo[3.2.1]octane compounds as ligands of the melanin concentrating hormone receptor
|
|
ES2547724T3
(es)
|
2004-11-10 |
2015-10-08 |
Incyte Corporation |
Compuestos de lactama y su uso como productos farmacéuticos
|
|
GT200500375A
(es)
|
2004-12-20 |
2006-11-28 |
|
Derivados de piperidina y su uso como agentes antiinflamatorios
|
|
WO2006066924A2
(en)
|
2004-12-23 |
2006-06-29 |
Chiesi Farmaceutici S.P.A. |
Azole derivatives with antimuscarinic activity
|
|
JP5274842B2
(ja)
|
2004-12-28 |
2013-08-28 |
エグゼリクシス, インコーポレイテッド |
免疫疾患、炎症疾患および増殖疾患の処置のためのセリン−スレオニンキナーゼモジュレーター(p70S6K、Akt−1およびAkt−2)としての[1H−ピペラゾ[3,4−d]ピリミジン−4−イル]−ピペラジンまたは[1H−ピペラゾ[3,4−d]ピリミジン−4−イル]−ピペラジン化合物
|
|
CN101107245A
(zh)
|
2005-01-19 |
2008-01-16 |
神经能质公司 |
经杂芳基取代的哌嗪-吡啶类似物
|
|
CN101142209A
(zh)
|
2005-02-16 |
2008-03-12 |
先灵公司 |
具有cxcr3拮抗剂活性的吡嗪基取代的哌嗪-哌啶
|
|
MX2007010068A
(es)
|
2005-02-16 |
2007-10-10 |
Schering Corp |
Piperazino-piperidinas con actividad antagonista de cxcr3.
|
|
US7417045B2
(en)
|
2005-02-16 |
2008-08-26 |
Schering Corporation |
Heterocyclic substituted pyridine or phenyl compounds with CXCR3 antagonist activity
|
|
ATE523506T1
(de)
|
2005-02-16 |
2011-09-15 |
Schering Corp |
Amingebundene pyridyl- und phenylsubstituierte piperazin-piperidine mit cxcr3-antagonistischer aktivität
|
|
MX2007009945A
(es)
|
2005-02-16 |
2007-09-26 |
Schering Corp |
Piperazinas sustituidas con heterociclicos con actividad antagonista de cxcr3.
|
|
WO2006088919A2
(en)
|
2005-02-16 |
2006-08-24 |
Schering Corporation |
Pyridyl and phenyl substituted piperazine-piperidines with cxcr3 antagonist activity
|
|
BRPI0607820A2
(pt)
|
2005-02-24 |
2010-03-23 |
Nihon Nohyaku Co Ltd |
derivado de haloalquilsulfonanilida ou um sal do mesmo, herbicida, e, mÉtodo para usar um herbicida
|
|
US20090264650A1
(en)
|
2005-03-31 |
2009-10-22 |
Nobuo Cho |
Prophylactic/Therapeutic Agent for Diabetes
|
|
EP1869024B1
(en)
|
2005-04-12 |
2010-11-10 |
Vicore Pharma AB |
New tricyclic angiotensin ii agonists
|
|
WO2006134481A1
(en)
*
|
2005-06-16 |
2006-12-21 |
Pfizer Inc. |
Inhibitors of 11-beta hydroxysteroid dehydrogenase type 1
|
|
WO2007008529A2
(en)
|
2005-07-08 |
2007-01-18 |
Kalypsys, Inc |
Celullar cholesterol absorption modifiers
|
|
CN101309690A
(zh)
|
2005-08-16 |
2008-11-19 |
阿诺麦德股份有限公司 |
趋化因子受体结合化合物
|
|
EP1937666B1
(en)
|
2005-10-11 |
2012-02-22 |
Schering Corporation |
Substituted heterocyclic compounds with cxcr3 antagonist activity
|
|
US7943605B2
(en)
|
2005-10-27 |
2011-05-17 |
Ucb Pharma S.A. |
Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses
|
|
CA2627306A1
(en)
|
2005-11-01 |
2007-05-10 |
Transtech Pharma, Inc. |
Pharmaceutical use of substituted amides
|
|
JP2007140188A
(ja)
|
2005-11-18 |
2007-06-07 |
Fujifilm Corp |
ポジ型感光性組成物及びそれを用いたパターン形成方法
|
|
AU2006316867A1
(en)
|
2005-11-22 |
2007-05-31 |
Amgen Inc. |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
|
|
US8193207B2
(en)
|
2005-12-05 |
2012-06-05 |
Incyte Corporation |
Lactam compounds and methods of using the same
|
|
EP1801098A1
(en)
|
2005-12-16 |
2007-06-27 |
Merck Sante |
2-Adamantylurea derivatives as selective 11B-HSD1 inhibitors
|
|
WO2007076055A2
(en)
|
2005-12-22 |
2007-07-05 |
Entremed, Inc. |
Compositions and methods comprising proteinase activated receptor antagonists
|
|
DE102005062990A1
(de)
|
2005-12-28 |
2007-07-05 |
Grünenthal GmbH |
Substituierte Thiazole und ihre Verwendung zur Herstellung von Arzneimitteln
|
|
US7910592B2
(en)
|
2005-12-30 |
2011-03-22 |
Merck Sharp & Dohme Corp. |
CETP inhibitors
|
|
EP2029560B1
(en)
|
2005-12-30 |
2013-04-24 |
Merck Sharp & Dohme Corp. |
1,3-oxazolidin-2-one derivatives useeful as cetp inhibitors
|
|
US8865707B2
(en)
|
2005-12-30 |
2014-10-21 |
Merck Sharp & Dohme Corp. |
Cholesteryl ester transfer protein inhibitors
|
|
AU2006335110B2
(en)
|
2005-12-30 |
2011-04-14 |
Merck Sharp & Dohme Corp. |
CETP inhibitors
|
|
US7998959B2
(en)
|
2006-01-12 |
2011-08-16 |
Incyte Corporation |
Modulators of 11-β hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
|
|
CA2643163C
(en)
|
2006-02-27 |
2020-01-28 |
Bayer Healthcare Llc |
Temperature-adjusted analyte determination for biosensor systems
|
|
US20070213311A1
(en)
|
2006-03-02 |
2007-09-13 |
Yun-Long Li |
Modulators of 11-beta hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
|
|
US20070208001A1
(en)
|
2006-03-03 |
2007-09-06 |
Jincong Zhuo |
Modulators of 11- beta hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
|
|
WO2007109456A2
(en)
|
2006-03-16 |
2007-09-27 |
Pharmacopeia, Inc. |
Substituted biphenyl isoxazole sulfonamides as dual angiotensin endothelin receptor antagonists
|
|
JP2007254409A
(ja)
|
2006-03-24 |
2007-10-04 |
Taisho Pharmaceut Co Ltd |
イミダゾリジノン誘導体
|
|
US7435833B2
(en)
|
2006-04-07 |
2008-10-14 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
|
|
BRPI0710380A2
(pt)
|
2006-04-20 |
2011-08-09 |
Du Pont |
composto, composição, composição de controle de pragas, invertebradas, de pulverização, de isca, dispositivo de armadilha, métodos de controle, métodos de proteção, semente tratada e composição de proteção
|
|
KR101055576B1
(ko)
|
2006-04-21 |
2011-08-08 |
일라이 릴리 앤드 캄파니 |
11-베타-히드록시스테로이드 데히드로게나제 1의 억제제로서의 시클로헥실피라졸-락탐 유도체
|
|
WO2007124329A1
(en)
|
2006-04-21 |
2007-11-01 |
Eli Lilly And Company |
Cyclohexylimidazole lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
|
|
WO2007124337A1
(en)
|
2006-04-21 |
2007-11-01 |
Eli Lilly And Company |
Biphenyl amide lactam derivatives as inhibitors of 11- beta-hydroxysteroid dehydrogenase 1
|
|
EA016959B1
(ru)
|
2006-04-24 |
2012-08-30 |
Эли Лилли Энд Компани |
Замещенные пирролидиноны в качестве ингибиторов 11-бета-гидроксистероиддегидрогеназы 1 типа
|
|
EA015499B1
(ru)
|
2006-04-25 |
2011-08-30 |
Эли Лилли Энд Компани |
Ингибиторы 11-бета-гидроксистероид дегидрогеназы типа 1
|
|
US8178005B2
(en)
|
2006-06-20 |
2012-05-15 |
Chemtura Corporation |
Liquid phosphite compositions having different alkyl groups
|
|
TW200811170A
(en)
|
2006-06-27 |
2008-03-01 |
Sanofi Aventis |
Urea derivatives of tropane, their preparation and their therapeutic application
|
|
WO2008012623A1
(en)
|
2006-07-25 |
2008-01-31 |
Pfizer Products Inc. |
Benzimidazolyl compounds as potentiators of mglur2 subtype of glutamate receptor
|
|
WO2008012622A2
(en)
|
2006-07-25 |
2008-01-31 |
Pfizer Products Inc. |
Azabenzimidazolyl compounds as potentiators of mglur2 subtype of glutamate receptor
|
|
US7649007B2
(en)
|
2006-08-15 |
2010-01-19 |
Wyeth Llc |
Oxazolidine derivatives as PR modulators
|
|
WO2008021337A1
(en)
|
2006-08-15 |
2008-02-21 |
Wyeth |
Oxazinan-2-one derivatives useful as pr modulators
|
|
WO2008021338A2
(en)
|
2006-08-15 |
2008-02-21 |
Wyeth |
Tricyclic oxazolidone derivatives useful as pr modulators
|
|
JP5420408B2
(ja)
|
2006-08-25 |
2014-02-19 |
ヴァイティー ファーマシューティカルズ,インコーポレイテッド |
11β−ヒドロキシステロイドデヒドロゲナーゼ1型のインヒビター
|
|
EP2061780A4
(en)
|
2006-09-14 |
2010-12-22 |
Zalicus Pharmaceuticals Ltd |
DIARYLE PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS
|
|
WO2008036715A1
(en)
|
2006-09-22 |
2008-03-27 |
Novartis Ag |
Heterocyclic organic compounds
|
|
DE102007005799B4
(de)
|
2006-10-18 |
2018-01-25 |
Heinz-Jürgen Mühlen |
Verfahren zur Erzeugung eines wasserstoffreichen Produktgases
|
|
BRPI0717657A2
(pt)
|
2006-10-19 |
2013-12-24 |
Hoffmann La Roche |
Compostos, processo para a preparação de um composto, composição farmacêutica que o compreende, usos de compostos, métodos para o tratamento e profilaxia de diabetes, obesidade, distúrbios alimentares, displidemia e hipertensão e profilaxia de diabetes do tipo ii
|
|
TW200829171A
(en)
|
2006-11-17 |
2008-07-16 |
Nihon Nohyaku Co Ltd |
Haloalkyl sulfonanilide derivatives or salts thereof, herbicide using it as effective constituent and use-method thereof
|
|
EP1935420A1
(en)
|
2006-12-21 |
2008-06-25 |
Merck Sante |
2-Adamantyl-butyramide derivatives as selective 11beta-HSD1 inhibitors
|
|
US8835426B2
(en)
|
2007-02-26 |
2014-09-16 |
Vitae Pharmaceuticals, Inc. |
Cyclic urea and carbamate inhibitors of 11β-hydroxysteroid dehydrogenase 1
|
|
EP2139911A2
(en)
|
2007-03-23 |
2010-01-06 |
Schering Corporation |
Hydrazido-peptides as inhibitors of hcv ns3-protease
|
|
CA2682639A1
(en)
|
2007-03-29 |
2008-10-09 |
F. Hoffmann-La Roche Ag |
Heterocyclic antiviral compounds
|
|
ES2395081T3
(es)
|
2007-07-26 |
2013-02-08 |
Vitae Pharmaceuticals, Inc. |
Síntesis de inhibidores de la 11beta-hidroxiesteroide deshidrogenasa de tipo 1
|
|
WO2009020140A1
(ja)
|
2007-08-06 |
2009-02-12 |
Dainippon Sumitomo Pharma Co., Ltd. |
アダマンチルウレア誘導体
|
|
JP2009110842A
(ja)
|
2007-10-31 |
2009-05-21 |
Sumitomo Chemical Co Ltd |
ボタンスイッチ被覆用積層樹脂体
|
|
AR069207A1
(es)
|
2007-11-07 |
2010-01-06 |
Vitae Pharmaceuticals Inc |
Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
|
|
US8859580B2
(en)
|
2007-11-16 |
2014-10-14 |
Boehringer Ingelheim International Gmbh |
Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
|
|
EP2229368A1
(en)
|
2007-12-11 |
2010-09-22 |
Vitae Pharmaceuticals, Inc. |
Cyclic urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
KR101460359B1
(ko)
|
2007-12-13 |
2014-11-10 |
삼성전자주식회사 |
이동통신 시스템에서의 핸드오버 방법 및 장치
|
|
TW200934490A
(en)
|
2008-01-07 |
2009-08-16 |
Vitae Pharmaceuticals Inc |
Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
|
|
JP5490020B2
(ja)
|
2008-01-24 |
2014-05-14 |
ヴァイティー ファーマシューティカルズ,インコーポレイテッド |
11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状カルバゼート及びセミカルバジドインヒビター
|
|
CA2714532A1
(en)
|
2008-02-11 |
2009-08-20 |
Vitae Pharmaceuticals, Inc. |
1,3-oxazepan-2-one and 1,3-diazepan-2-one inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
|
|
US20110028445A1
(en)
|
2008-02-12 |
2011-02-03 |
Boehringer Ingelheim International Gmbh |
Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
|
|
JP5730021B2
(ja)
|
2008-02-15 |
2015-06-03 |
ヴァイティー ファーマシューティカルズ,インコーポレイテッド |
11β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤としてのシクロアルキルラクタム誘導体
|
|
JP5108557B2
(ja)
|
2008-02-27 |
2012-12-26 |
東京エレクトロン株式会社 |
ロードロック装置および基板冷却方法
|
|
EP2265588B1
(en)
|
2008-02-27 |
2013-06-26 |
Vitae Pharmaceuticals, Inc. |
INHIBITORS OF 11ß -HYDROXYSTEROID DEHYDROGENASE TYPE 1
|
|
EP2274287B1
(en)
|
2008-03-18 |
2016-03-09 |
Vitae Pharmaceuticals, Inc. |
Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1
|
|
TW200944526A
(en)
|
2008-04-22 |
2009-11-01 |
Vitae Pharmaceuticals Inc |
Carbamate and urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
|
|
CA2723032A1
(en)
|
2008-05-01 |
2009-11-05 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
CA2723034A1
(en)
|
2008-05-01 |
2009-11-05 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
CL2009001058A1
(es)
|
2008-05-01 |
2010-09-10 |
Vitae Pharmaceuticals Inc |
Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras.
|
|
TW200946520A
(en)
|
2008-05-01 |
2009-11-16 |
Vitae Pharmaceuticals Inc |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
CA2724214A1
(en)
|
2008-05-13 |
2009-11-19 |
Boehringer Ingelheim International Gmbh |
Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
|
|
US20110224242A1
(en)
|
2008-07-23 |
2011-09-15 |
Bioalliance Pharma |
Styrlyquinolines, their process of preparation and their therapeutic uses
|
|
WO2010010149A1
(en)
|
2008-07-23 |
2010-01-28 |
Bioalliance Pharma |
Styrylquinolines, their process of preparation and their therapeutic uses
|
|
EP2324018B1
(en)
|
2008-07-25 |
2013-09-04 |
Boehringer Ingelheim International GmbH |
Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1
|
|
CA2729998A1
(en)
|
2008-07-25 |
2010-01-28 |
Boehringer Ingelheim International Gmbh |
Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
JP5390610B2
(ja)
|
2008-07-25 |
2014-01-15 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
11β−ヒドロキシステロイドデヒドロゲナーゼ1型の阻害剤の合成
|
|
WO2010127237A2
(en)
|
2009-04-30 |
2010-11-04 |
Boehringer Ingelheim International Gmbh |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
CA2730208C
(en)
|
2008-07-25 |
2016-10-25 |
Boehringer Ingelheim International Gmbh |
1,1'-diadamantyl carboxylic acids, medicaments containing such compounds and their use
|
|
JP5586605B2
(ja)
|
2008-08-25 |
2014-09-10 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
置換ノルトロパンのアリール及びヘテロアリールカルボニル誘導体、該化合物を含有する医薬及びその使用
|
|
CA2738453C
(en)
|
2008-10-23 |
2017-07-04 |
Boehringer Ingelheim International Gmbh |
Urea derivatives of substituted nortropanes, medicaments containing such compounds and their use
|
|
WO2010091067A2
(en)
|
2009-02-04 |
2010-08-12 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
JP5679997B2
(ja)
|
2009-02-04 |
2015-03-04 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状阻害剤
|
|
EP2405913A1
(en)
|
2009-03-09 |
2012-01-18 |
Bristol-Myers Squibb Company |
Pyridone analogs useful as melanin concentrating hormone receptor-1 antagonists
|
|
UA109255C2
(ru)
|
2009-04-30 |
2015-08-10 |
Берінгер Інгельхайм Інтернешнл Гмбх |
Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1
|
|
AR076936A1
(es)
|
2009-06-02 |
2011-07-20 |
Vitae Pharmaceuticals Inc |
Inhibidores de carbamato y urea de la 11 beta hidroxiesteroide deshidrogenasa 1
|
|
US8703765B2
(en)
|
2009-06-02 |
2014-04-22 |
Boehringer Ingelheim International Gmbh |
Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
|
|
EP2440537A1
(en)
|
2009-06-11 |
2012-04-18 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
|
|
WO2011002910A1
(en)
|
2009-07-01 |
2011-01-06 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
BR112012005550A2
(pt)
|
2009-09-11 |
2015-09-08 |
Cylene Pharmaceuticals Inc |
lactamas heterociclo-substituídas farmaceuticamente úteis
|
|
WO2011056737A1
(en)
|
2009-11-05 |
2011-05-12 |
Boehringer Ingelheim International Gmbh |
Novel chiral phosphorus ligands
|
|
UY33001A
(es)
|
2009-11-06 |
2011-05-31 |
Boehringer Ingelheim Int |
Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
|
|
WO2011159760A1
(en)
|
2010-06-16 |
2011-12-22 |
Vitae Pharmaceuticals, Inc. |
Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
|
|
WO2011161128A1
(en)
|
2010-06-25 |
2011-12-29 |
Boehringer Ingelheim International Gmbh |
Azaspirohexanones as inhibitors of 11-beta-hsd1 for the treatment of metabolic disorders
|
|
EA201300522A1
(ru)
|
2010-11-02 |
2013-11-29 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Фармацевтические комбинации для лечения метаболических нарушений
|