JP2009530298A5 - - Google Patents

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JP2009530298A5
JP2009530298A5 JP2009500494A JP2009500494A JP2009530298A5 JP 2009530298 A5 JP2009530298 A5 JP 2009530298A5 JP 2009500494 A JP2009500494 A JP 2009500494A JP 2009500494 A JP2009500494 A JP 2009500494A JP 2009530298 A5 JP2009530298 A5 JP 2009530298A5
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weight
formulation
preparation according
coating
barrier coating
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JP2009500494A
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JP2009530298A (ja
JP5479086B2 (ja
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Priority claimed from PCT/US2007/006572 external-priority patent/WO2007109104A2/en
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JP2009500494A 2006-03-16 2007-03-15 薬剤−イオン交換樹脂複合体を含有する放出調節製剤 Active JP5479086B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78318106P 2006-03-16 2006-03-16
US60/783,181 2006-03-16
PCT/US2007/006572 WO2007109104A2 (en) 2006-03-16 2007-03-15 Modified release formulations containing drug-ion exchange resin complexes

Publications (3)

Publication Number Publication Date
JP2009530298A JP2009530298A (ja) 2009-08-27
JP2009530298A5 true JP2009530298A5 (enExample) 2010-05-06
JP5479086B2 JP5479086B2 (ja) 2014-04-23

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JP2009500494A Active JP5479086B2 (ja) 2006-03-16 2007-03-15 薬剤−イオン交換樹脂複合体を含有する放出調節製剤

Country Status (14)

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US (23) US8062667B2 (enExample)
EP (2) EP2428205B1 (enExample)
JP (1) JP5479086B2 (enExample)
KR (1) KR101495146B1 (enExample)
CN (2) CN101400343B (enExample)
AT (1) ATE536867T1 (enExample)
BR (1) BRPI0709606B8 (enExample)
CA (1) CA2645855C (enExample)
DK (2) DK2018160T3 (enExample)
ES (2) ES2378573T3 (enExample)
IL (1) IL194042A (enExample)
RU (1) RU2435569C2 (enExample)
TW (1) TW200812649A (enExample)
WO (1) WO2007109104A2 (enExample)

Families Citing this family (146)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2957281A1 (en) 2001-09-21 2015-12-23 Egalet Ltd. Polymer release system
WO2003024430A1 (en) 2001-09-21 2003-03-27 Egalet A/S Morphine polymer release system
ATE495732T1 (de) 2003-03-26 2011-02-15 Egalet As Morphin-system mit kontrollierter freisetzung
US7201920B2 (en) 2003-11-26 2007-04-10 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of opioid containing dosage forms
US8343546B2 (en) * 2005-09-13 2013-01-01 Coating Place, Inc. Ion exchange resin treated to control swelling
CA2645855C (en) 2006-03-16 2015-02-03 Tris Pharma, Inc. Modified release formulations containing drug-ion exchange resin complexes
US8287848B2 (en) 2006-10-03 2012-10-16 Tris Pharma Inc Formulations containing an ionic mineral-ion exchange resin complex and uses thereof
WO2008129501A2 (en) * 2007-04-20 2008-10-30 Wockhardt Research Centre Pharmaceutical compositions of duloxetine
US8202542B1 (en) 2007-05-31 2012-06-19 Tris Pharma Abuse resistant opioid drug-ion exchange resin complexes having hybrid coatings
EP2155167A2 (en) 2007-06-04 2010-02-24 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
PL2187873T3 (pl) 2007-08-13 2019-01-31 Abuse Deterrent Pharmaceutical Llc Leki odporne na nadużywanie, metoda stosowania i metoda wytwarzania
USRE48948E1 (en) 2008-04-18 2022-03-01 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable polymer
WO2009130715A1 (en) * 2008-04-25 2009-10-29 Cadila Healtcare Limited Rapidly disintegrating oral compositions of tramadol
GB0814466D0 (en) * 2008-08-07 2008-09-10 Rosemont Pharmaceuticals Ltd Sertraline composition
CA2638240C (en) 2008-08-29 2010-02-02 Alexander Macgregor Method of treating dysglycemia and glucose excursions
EP2393484A1 (en) 2009-02-06 2011-12-14 Egalet Ltd. Immediate release composition resistant to abuse by intake of alcohol
US20100280059A1 (en) * 2009-05-01 2010-11-04 Atley Pharmaceuticals, Inc. Compositions comprising an antihistamine, antitussive and decongestant in extended release formulations
WO2010127100A1 (en) * 2009-05-01 2010-11-04 Atley Pharmaceuticals, Inc. Compositions comprising an antihistamine, antitussive and decongestant in extented release formulations
EP2445487A2 (en) 2009-06-24 2012-05-02 Egalet Ltd. Controlled release formulations
ES2569925T3 (es) 2009-09-30 2016-05-13 Acura Pharmaceuticals, Inc. Métodos y composiciones de disuasión del abuso
MX377251B (es) 2010-03-24 2025-03-07 Jazz Pharmaceuticals Inc Star Formas de dosis de liberacion controlada para substancias de farmaco de alta dosis, solubles en agua e higroscopicas.
US9211292B2 (en) * 2010-04-21 2015-12-15 Alitair Pharmaceuticals Inc Preventing or reducing drug abuse and overdose events
US8617602B2 (en) * 2010-09-03 2013-12-31 William Wayne Howard Immediate release compositions and methods for delivering drug formulations using weak acid ion exchange resins in abnormally high pH environments
US8623409B1 (en) * 2010-10-20 2014-01-07 Tris Pharma Inc. Clonidine formulation
US20130230587A1 (en) 2010-11-10 2013-09-05 Rubicon Research Private Limited Sustained release compositions
EP2675438B1 (en) 2011-02-15 2019-04-10 Tris Pharma, Inc. Extended release powder and aqueous suspension comprising methylphenidate
US8287903B2 (en) 2011-02-15 2012-10-16 Tris Pharma Inc Orally effective methylphenidate extended release powder and aqueous suspension product
EP2726066B1 (en) 2011-06-28 2021-03-31 Neos Therapeutics, LP Dosage forms of amphetamine for oral administration
EP2726065A4 (en) * 2011-06-30 2014-11-26 Neos Therapeutics Lp MISS-BROKEN MEDICINAL PRODUCTS
US20130105399A1 (en) * 2011-11-02 2013-05-02 University Of Illinois Urbana Champaign Polymer-encapsulated liquid exchange media
EP2836201A1 (en) * 2011-12-14 2015-02-18 Wockhardt Limited Modified release liquid pharmaceutical composition comprising bromopheniramine, pseudoephedrine and dextromethorphan
WO2013119231A1 (en) * 2012-02-09 2013-08-15 Tris Pharma, Inc. Abuse resistant opioid drug - ion exchange resin complexes having hybrid coatings
MX356111B (es) 2012-04-18 2018-05-15 SpecGx LLC Composiciones farmaceuticas disuasorias de abuso, de liberacion inmediata.
CA2870134C (en) * 2012-05-02 2020-04-28 Capsugel France SAS Aqueous dispersions of hydroxypropyl methylcellulose acetate succinate (hpmcas)
KR20150059167A (ko) 2012-07-06 2015-05-29 에갈렛 리미티드 제어된 방출을 위한 남용 제지 약학적 조성물
DK2884961T3 (en) * 2012-08-15 2019-04-23 Tris Pharma Inc METHYLPHENIDATE TABLE WITH EXTENDED RELEASE
CN102885791B (zh) * 2012-09-24 2015-03-04 浙江万晟药业有限公司 一种制备盐酸非索非那定口腔崩解片的方法
EP3446685A1 (en) 2012-11-30 2019-02-27 Acura Pharmaceuticals, Inc. Self-regulated release of active pharmaceutical ingredient
WO2014095818A1 (en) * 2012-12-20 2014-06-26 Synthon B.V. Formulation comprising amorphous agomelatine
EP2749309B1 (en) 2012-12-28 2016-04-27 Cook Medical Technologies LLC Ion exchange ureteral stent
US9180104B2 (en) 2013-03-13 2015-11-10 Tris Pharma, Inc. Benzonatate modified release solid tablets and capsules
AU2014240988B9 (en) 2013-03-13 2019-01-03 Tris Pharma, Inc. Benzonatate modified release solid tablets and capsules
EP2968182B8 (en) 2013-03-15 2018-07-25 SpecGx LLC Abuse deterrent solid dosage form for immediate release with functional score
US10420729B2 (en) * 2013-03-15 2019-09-24 R.P. Scherer Technologies, Llc Abuse resistant capsule
US20140271891A1 (en) * 2013-03-15 2014-09-18 Mcneil-Ppc, Inc. Phenylephrine resinate particles and use thereof in pharmaceutical formulations
US20140275149A1 (en) 2013-03-15 2014-09-18 Inspirion Delivery Technologies, Llc Abuse deterrent compositions and methods of use
US20140271892A1 (en) * 2013-03-15 2014-09-18 Mcneil-Ppc, Inc. Phenylephrine resinate particles having good auc
US20140271893A1 (en) 2013-03-15 2014-09-18 Mcneil-Ppc, Inc. Coated phenylephrine particles and use thereof in pharmaceutical formulations
US9782516B2 (en) * 2013-03-15 2017-10-10 Abbott Cardiovascular Systems Inc. Tissue adhesive coatings for drug coated balloon
US10098848B2 (en) 2013-04-11 2018-10-16 Richard Louis Price Inositol-containing comestible units and methods of treatment using the same
US9211284B2 (en) 2013-04-11 2015-12-15 Richard Louis Price Diagnosis and treatment of P.R.I.C.E. syndrome
US20140309270A1 (en) 2013-04-11 2014-10-16 Richard Louis Price Diagnosis and treatment of a form of autistic spectrum disorder
US9603812B2 (en) 2013-04-11 2017-03-28 Richard Louis Price Treatment of autistic spectrum disorder
US20170348417A1 (en) 2013-04-11 2017-12-07 Richard Louis Price Treatment of attention deficit disorders and associated symptoms
AU2014306759B2 (en) 2013-08-12 2018-04-26 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
US9770514B2 (en) 2013-09-03 2017-09-26 ExxPharma Therapeutics LLC Tamper-resistant pharmaceutical dosage forms
US20160220512A1 (en) * 2013-09-15 2016-08-04 Rubicon Research Private Limited Modified release pharmaceutical formulations
EP3065720A1 (en) 2013-11-04 2016-09-14 Capsugel Belgium NV Methods and systems for improved bioavailability of active pharmaceutical ingredients including esomeprazole
WO2015076821A1 (en) * 2013-11-22 2015-05-28 Tris Pharma, Inc. Novel clonidine formulation
EP2875817B1 (en) * 2013-11-26 2020-03-18 Synhton B.V. Pharmaceutical formulation comprising amorphous lenalidomide
CA2931547A1 (en) 2013-12-09 2015-06-18 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
WO2015095391A1 (en) 2013-12-17 2015-06-25 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
CA2938699A1 (en) 2014-02-05 2015-08-13 Kashiv Pharma Llc Abuse-resistant drug formulations with built-in overdose protection
CN103860464B (zh) * 2014-03-19 2016-03-16 广州帝奇医药技术有限公司 一种抗过敏药物缓释混悬剂及其制备方法
US9616029B2 (en) 2014-03-26 2017-04-11 Sun Pharma Advanced Research Company Ltd. Abuse deterrent immediate release coated reservoir solid dosage form
WO2016016845A1 (en) 2014-07-30 2016-02-04 Sun Pharmaceutical Industries Limited Dual-chamber pack
US20180104197A9 (en) 2014-05-01 2018-04-19 Sun Pharmaceutical Industries Limited Extended release liquid compositions of metformin
US9962336B2 (en) 2014-05-01 2018-05-08 Sun Pharmaceutical Industries Limited Extended release suspension compositions
US10258583B2 (en) 2014-05-01 2019-04-16 Sun Pharmaceutical Industries Limited Extended release liquid compositions of guanfacine
JP2017514903A (ja) 2014-05-01 2017-06-08 サン ファーマシューティカル インダストリーズ リミテッドSun Pharmaceutical Industries Ltd. 徐放性懸濁組成物
US20170095432A1 (en) * 2014-06-13 2017-04-06 United Therapeutics Corporation Treprostinil formulations
CN104027306A (zh) * 2014-06-25 2014-09-10 万特制药(海南)有限公司 帕罗西汀口服混悬液及其制备方法
WO2016001937A2 (en) * 2014-06-30 2016-01-07 Rubicon Research Private Limited Modified release pharmaceutical preparations
PL3164117T3 (pl) 2014-07-03 2024-03-11 SpecGx LLC Preparaty zapewniające natychmiastowe uwalnianie i powstrzymujące przed nadużywaniem, zawierające polisacharydy inne niż celuloza
EP3169311B1 (en) 2014-07-17 2023-08-02 Pharmathen S.A. Pediatric powder for oral suspension containing antiviral agent and method for the preparation thereof
US12458645B2 (en) 2014-07-17 2025-11-04 Pharmathen S. A. Pediatric powder for oral suspension containing antiviral agent and method for the preparation thereof
WO2016010771A1 (en) 2014-07-17 2016-01-21 Pharmaceutical Manufacturing Research Services, Inc. Immediate release abuse deterrent liquid fill dosage form
US10729685B2 (en) 2014-09-15 2020-08-04 Ohemo Life Sciences Inc. Orally administrable compositions and methods of deterring abuse by intranasal administration
CA2964628A1 (en) 2014-10-20 2016-04-28 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
MA41152A (fr) * 2014-12-12 2017-10-17 Johnson & Johnson Consumer Inc Procédé de fabrication de particules de résinate de phényléphrine ; particules de résinate de phényléphrine et utilisation des particules de résinate de phényléphrine dans des formulations pharmaceutiques
CN104628587B (zh) * 2015-02-12 2016-06-22 艾美科健(中国)生物医药有限公司 一种回收阿莫西林生产废液中d-对羟基苯甘氨酸的方法
US10398662B1 (en) 2015-02-18 2019-09-03 Jazz Pharma Ireland Limited GHB formulation and method for its manufacture
EP3288539A4 (en) * 2015-05-01 2019-07-10 Sun Pharmaceutical Industries Ltd EXTENDED RELEASE LIQUID METFORMIN COMPOSITIONS
WO2017040607A1 (en) 2015-08-31 2017-03-09 Acura Pharmaceuticals, Inc. Methods and compositions for self-regulated release of active pharmaceutical ingredient
US11590228B1 (en) * 2015-09-08 2023-02-28 Tris Pharma, Inc Extended release amphetamine compositions
US9849125B1 (en) 2015-11-03 2017-12-26 Banner Lifie Sciences LLC Anti-overingestion dosage forms
US10358894B2 (en) * 2015-12-11 2019-07-23 Dreco Energy Services Ulc System for placing a tracer in a well
CN105663038B (zh) * 2016-02-03 2019-06-14 北京诺康达医药科技股份有限公司 一种液体缓释制剂及其制备方法
US11938224B1 (en) 2016-04-08 2024-03-26 Tris Pharma Inc Benzonatate modified release solid tablets and capsules
US11311623B2 (en) 2016-04-21 2022-04-26 Fertin Pharma A/S Nicotine delivery product, related uses and oral dosage forms, and methods of production
US10238803B2 (en) 2016-05-02 2019-03-26 Sun Pharmaceutical Industries Limited Drug delivery device for pharmaceutical compositions
US10369078B2 (en) 2016-05-02 2019-08-06 Sun Pharmaceutical Industries Limited Dual-chamber pack for pharmaceutical compositions
KR20180132955A (ko) * 2016-05-03 2018-12-12 스펙트릭스 테라퓨틱스, 엘엘씨 갑상샘 호르몬 또는 이의 유사체를 제공하는 조성물 및 방법
US12478604B1 (en) 2016-07-22 2025-11-25 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11602513B1 (en) 2016-07-22 2023-03-14 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11602512B1 (en) 2016-07-22 2023-03-14 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
UY37341A (es) 2016-07-22 2017-11-30 Flamel Ireland Ltd Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada
US11504347B1 (en) 2016-07-22 2022-11-22 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US12186296B1 (en) 2016-07-22 2025-01-07 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11986451B1 (en) 2016-07-22 2024-05-21 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
EP3522890A4 (en) 2016-10-10 2020-06-03 Rhodes Pharmaceuticals L.P. PHARMACEUTICAL RESINATE COMPOSITIONS AND METHOD FOR THE PRODUCTION AND USE THEREOF
GB2555442B (en) 2016-10-27 2022-06-01 Oxford Pharmascience Ltd Modifier system for compositions containing layered double hydroxide
CN106344522B (zh) * 2016-11-11 2019-04-09 河北利华药业有限公司 一种兽用阿莫西林颗粒及其制备方法
US9855228B1 (en) * 2016-12-14 2018-01-02 Taho Pharmaceuticals Ltd. Oral solution comprising atomoxetine hydrochloride and methods thereof
CN106632804A (zh) * 2016-12-31 2017-05-10 重庆文理学院 绿色阳离子交换树脂制备方法
US12453732B2 (en) 2017-01-14 2025-10-28 Pharmathen S. A. Pediatric powder for oral suspension containing antiviral agent and method for the preparation thereof
US20180263936A1 (en) 2017-03-17 2018-09-20 Jazz Pharmaceuticals Ireland Limited Gamma-hydroxybutyrate compositions and their use for the treatment of disorders
US10335375B2 (en) 2017-05-30 2019-07-02 Patheon Softgels, Inc. Anti-overingestion abuse deterrent compositions
WO2019032975A1 (en) * 2017-08-10 2019-02-14 Mec Device Pharma International Llc ANTI-ABUSE MEDICINAL FORMULATIONS
US11590081B1 (en) 2017-09-24 2023-02-28 Tris Pharma, Inc Extended release amphetamine tablets
US12458592B1 (en) 2017-09-24 2025-11-04 Tris Pharma, Inc. Extended release amphetamine tablets
JP2020536892A (ja) * 2017-10-09 2020-12-17 ローズ ファーマシューティカルズ エル.ピー. 医薬レジネート組成物、それを作製する方法、およびその使用
GR1009534B (el) * 2017-11-21 2019-05-31 Laboserve Φαρμακευτικη Βιομηχανια Α.Ε. Ποσιμα φαρμακευτικα διαλυματα που περιλαμβανουν υδροχλωρικη οξυβουτυνινη
CN108014120A (zh) * 2017-12-18 2018-05-11 中国药科大学 一种释药速度可控的阿奇霉素树脂复合物及其掩味干混悬剂
WO2019126216A1 (en) 2017-12-18 2019-06-27 Tris Phama, Inc. Pharmaceutical compositions comprising a floating interpenetrating polymer network forming system
US11337919B2 (en) 2017-12-18 2022-05-24 Tris Pharma, Inc. Modified release drug powder composition comprising gastro-retentive RAFT forming systems having trigger pulse drug release
US11337920B2 (en) 2017-12-18 2022-05-24 Tris Pharma, Inc. Pharmaceutical composition comprising GHB gastro-retentive raft forming systems having trigger pulse drug release
IL275312B2 (en) 2017-12-18 2024-09-01 Tris Pharma Inc Ghb pharmaceutical compositions comprising a floating interpenetrating polymer network forming system
CN108030770A (zh) * 2017-12-18 2018-05-15 中国药科大学 含有药物树脂复合物的释药可控的干混悬剂及其制备方法
AU2018390826B2 (en) 2017-12-20 2024-09-12 Purdue Pharma L.P. Abuse deterrent morphine sulfate dosage forms
KR20200117999A (ko) * 2017-12-22 2020-10-14 디디피 스페셜티 일렉트로닉 머티리얼즈 유에스 8 엘엘씨 수지 입자를 함유하는 약학적 조성물
FR3079303A1 (fr) 2018-03-20 2019-09-27 Ab7 Innovation Procede pour la detection de la presence d'un traceur dans les excrements
KR20210057756A (ko) * 2018-09-07 2021-05-21 알.피.쉐러 테크놀러지즈 엘엘씨 경화 및 낮은 hlb 계면 활성제(들)의 첨가를 통한 고체 또는 반고체 지질 기반 제형 안정화
EP3856160A4 (en) 2018-09-25 2022-07-06 SpecGx LLC ANTI-ABUSE IMMEDIATE RELEASE CAPSULES DOSAGE FORMS
AU2019383389A1 (en) 2018-11-19 2021-05-06 Jazz Pharmaceuticals Ireland Limited Alcohol-resistant drug formulations
WO2020178695A1 (en) 2019-03-01 2020-09-10 Flamel Ireland Limited Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state
US11602507B2 (en) 2019-05-27 2023-03-14 Trikona Pharmaceuticals Pvt. Ltd Extended release oral composition of memantine or its salt and its process for the preparation
US20220241222A1 (en) * 2019-06-26 2022-08-04 Celista Pharmaceuticals Llc Atomoxetine hydrochloride extended release compositions and methods of use
WO2021071902A1 (en) * 2019-10-10 2021-04-15 Brillian Pharma Inc. Micronized drug resinate-based pharmaceutical compositions and methods of preparation thereof
TW202139986A (zh) 2020-02-21 2021-11-01 愛爾蘭商爵士製藥愛爾蘭有限責任公司 治療原發性嗜睡症之方法
US20230158160A1 (en) * 2020-05-23 2023-05-25 Lyrus Life Sciences Pvt. Ltd. Pharmaceutical composition of extended-release oral suspension and process for preparation thereof
CN111617032A (zh) * 2020-07-08 2020-09-04 江苏四环生物制药有限公司 一种布洛芬药物纤维混悬剂及其制备方法
US11918689B1 (en) 2020-07-28 2024-03-05 Tris Pharma Inc Liquid clonidine extended release composition
CN112362765B (zh) * 2020-10-13 2022-06-17 长沙都正生物科技股份有限公司 一种多塞平及其代谢产物n-去甲多塞平固相萃取、检测方法及试剂盒
CN114088680B (zh) * 2021-10-14 2023-06-27 安徽中科赛飞尔科技有限公司 一种染发样品中痕量毒品的快速检测方法
JP2025504042A (ja) * 2022-01-26 2025-02-06 トゥレックス・ファーマシューティカルズ・インコーポレイテッド 新規組成物
US11779557B1 (en) 2022-02-07 2023-10-10 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11583510B1 (en) 2022-02-07 2023-02-21 Flamel Ireland Limited Methods of administering gamma hydroxybutyrate formulations after a high-fat meal
KR102881925B1 (ko) * 2022-02-22 2025-11-06 인제대학교 산학협력단 양이온교환수지를 사용한 약물의 방출 조절을 위한 조성물
CN115350152A (zh) * 2022-07-27 2022-11-18 武汉科福新药有限责任公司 一种普萘洛尔缓释口服混悬液及其制备方法
KR20250041170A (ko) 2022-07-29 2025-03-25 드로타스타 엘엘씨 항경련제의 안정한 약제학적 경구용 액체 제형
CN121038779A (zh) 2023-02-03 2025-11-28 特瑞斯制药公司 每晚一次的低钠羟丁酸盐组合物
CN117679397B (zh) * 2023-12-22 2025-06-13 湖北广济医药科技有限公司 一种布瓦西坦缓释干混悬剂及其制备方法
WO2025165367A1 (en) 2024-02-02 2025-08-07 Tris Pharma, Inc. Liquid clonidine extended release composition
CN119564603B (zh) * 2024-12-18 2025-08-05 平光制药股份有限公司 马来酸曲美布汀树脂复合物缓释混悬液及其制备方法

Family Cites Families (223)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US659463A (en) 1899-11-18 1900-10-09 E & A H Batcheller Company Heel-attaching machine.
US692988A (en) 1901-05-20 1902-02-11 Seneca Falls Mfg Company Drill-chuck.
US2099402A (en) 1934-01-17 1937-11-16 Pratt Food Company Pill or tablet
US2507631A (en) 1944-01-19 1950-05-16 Ciba Pharm Prod Inc Pyridine and piperidine compounds and process of making same
US2957880A (en) 1953-12-23 1960-10-25 Ciba Pharm Prod Inc Process for the conversion of stereoisomers
US2830933A (en) 1955-07-14 1958-04-15 Pfizer & Co C Vitamin b12 products and preparation thereof
US2809918A (en) 1955-10-17 1957-10-15 Victor M Hermelin Sustained release pharmaceutical preparations
US2990332A (en) 1958-04-02 1961-06-27 Wallace & Tiernan Inc Pharmaceutical preparations comprising cation exchange resin adsorption compounds and treatment therewith
US3048526A (en) 1958-08-04 1962-08-07 Wander Company Medicinal tablet
US3146919A (en) 1960-10-17 1964-09-01 Story F Chappell Ball follower dispenser
US3138525A (en) 1961-06-16 1964-06-23 Hoffmann La Roche Castor wax-amprotropine-resin compositions
US3499960A (en) 1965-01-25 1970-03-10 Merck & Co Inc Palatable coated particles of an anion exchange resin
US3365365A (en) 1965-08-09 1968-01-23 Hoffmann La Roche Repeat action pharmaceutical compositions in the form of discrete beadlets
US3594470A (en) 1968-02-19 1971-07-20 Abbott Lab Chewable tablets including coated particles of pseudoephedrine-weak cation exchange resin
GB1218102A (en) 1968-03-15 1971-01-06 Philips Nv Improvements in medicaments comprising drug/ion-exchange resin compounds
US3567079A (en) 1968-08-08 1971-03-02 Cleone H Weigand Dispenser container with metering neck
LU63060A1 (enExample) 1971-04-26 1971-08-26
DE2246037B2 (de) 1972-09-20 1975-02-27 Taeschner & Co, 8831 Kipfenberg Peroral anwendbares Arzneimittel mit verzögerter Resorbierbarkeit in Suspensionsform
DE2322883A1 (de) 1973-05-07 1974-11-28 Roehm Gmbh Wasserloesliche polymerisate
US4221778A (en) 1979-01-08 1980-09-09 Pennwalt Corporation Prolonged release pharmaceutical preparations
US4363323A (en) 1980-12-04 1982-12-14 Geiss Alan C Nasogastric tube adapted to avoid pressure necrosis
JPS5941574U (ja) 1982-09-07 1984-03-17 三菱鉛筆株式会社 ボ−ルペン
CH655507B (enExample) * 1983-01-12 1986-04-30
US4459278A (en) 1983-03-07 1984-07-10 Clear Lake Development Group Composition and method of immobilizing emetics and method of treating human beings with emetics
US4765989A (en) 1983-05-11 1988-08-23 Alza Corporation Osmotic device for administering certain drugs
US4762709A (en) * 1983-09-16 1988-08-09 Pennwalt Corporation Liquid prolonged release pharmaceutical formulations containing ionic constituents
IE56999B1 (en) 1983-12-22 1992-03-11 Elan Corp Plc Pharmaceutical formulation
US4894240A (en) 1983-12-22 1990-01-16 Elan Corporation Plc Controlled absorption diltiazem formulation for once-daily administration
US4876094A (en) * 1984-01-13 1989-10-24 Battelle Development Corporation Controlled release liquid dosage formulation
US4552899A (en) 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
US4847077A (en) 1984-07-18 1989-07-11 Pennwalt Corporation Controlled release pharmaceutical preparations
IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US4600645A (en) 1985-01-31 1986-07-15 Warner-Lambert Company Process for treating dosage forms
US4619673A (en) 1985-05-15 1986-10-28 Multiform Desiccants, Inc. Adsorbent device
EP0227814A1 (en) 1985-07-02 1987-07-08 The Upjohn Company Therapeutic formulations with bimodal release characteristics
GB8518301D0 (en) 1985-07-19 1985-08-29 Fujisawa Pharmaceutical Co Hydrodynamically explosive systems
JPS62103012A (ja) 1985-10-23 1987-05-13 Eisai Co Ltd 多重顆粒
US4775536A (en) 1986-02-24 1988-10-04 Bristol-Myers Company Enteric coated tablet and process for making
US4794001A (en) 1986-03-04 1988-12-27 American Home Products Corporation Formulations providing three distinct releases
DE3617432A1 (de) 1986-05-23 1987-11-26 Standard Elektrik Lorenz Ag Elektronenstrahlerzeugungssystem
US4859461A (en) * 1986-07-30 1989-08-22 Fisons Corporation Coatable ion exchange resins
US4752470A (en) 1986-11-24 1988-06-21 Mehta Atul M Controlled release indomethacin
GB2201395B (en) 1986-12-17 1990-05-02 English Glass Co Ltd Liquid dosing device
US4910932A (en) 1987-01-05 1990-03-27 Honigman Michael L Modular building system
US4894239A (en) 1987-06-02 1990-01-16 Takeda Chemical Industries, Ltd. Sustained-release preparation and production thereof
US4808411A (en) 1987-06-05 1989-02-28 Abbott Laboratories Antibiotic-polymer compositions
GB2206880B (en) 1987-07-16 1991-04-24 Farmos Oy Optical isomers of an imidazole derivative
IL87710A (en) 1987-09-18 1992-06-21 Ciba Geigy Ag Covered floating retard form for controlled release in gastric juice
IL90245A (en) 1988-05-11 1994-04-12 Glaxo Group Ltd Resin adsorbate comprising ranitidine together with a synthetic cation exchange resin, its preparation and pharmaceutical compositions containing it
US5219563A (en) * 1988-05-11 1993-06-15 Glaxo Group Limited Drug adsorbates
JPH01287270A (ja) 1988-05-13 1989-11-17 Matsushita Electric Ind Co Ltd スパッタリング装置
JPH0217912A (ja) 1988-07-06 1990-01-22 Matsushita Electric Ind Co Ltd 空気清浄機
US5296236A (en) 1988-09-16 1994-03-22 Recordati S.A., Chemical And Pharmaceutical Company Controlled release therapeutic system for a liquid pharmaceutical formulations
US4996047A (en) * 1988-11-02 1991-02-26 Richardson-Vicks, Inc. Sustained release drug-resin complexes
CA2002492A1 (en) 1988-11-11 1990-05-11 Sandra T. A. Malkowska Pharmaceutical ion exchange resin composition
US5186930A (en) 1988-11-14 1993-02-16 Schering Corporation Sustained release oral suspensions
US4999189A (en) 1988-11-14 1991-03-12 Schering Corporation Sustained release oral suspensions
US5275819A (en) 1989-02-06 1994-01-04 Amer Particle Technologies Inc. Drug loaded pollen grains with an outer coating for pulsed delivery
GB2230442B (en) 1989-02-16 1992-11-25 Nat Res Dev Controlled release device
JP3126127B2 (ja) 1989-04-28 2001-01-22 アジレント・テクノロジー株式会社 試験データ圧縮方式
NZ234143A (en) * 1989-06-28 1991-10-25 Mcneil Ppc Inc Aqueous pharmaceutical suspension formulation for administering substantially insoluble pharmaceutical agents
US5158777A (en) 1990-02-16 1992-10-27 E. R. Squibb & Sons, Inc. Captopril formulation providing increased duration of activity
US5156850A (en) 1990-08-31 1992-10-20 Alza Corporation Dosage form for time-varying patterns of drug delivery
US5422121A (en) 1990-11-14 1995-06-06 Rohm Gmbh Oral dosage unit form
US5275820A (en) 1990-12-27 1994-01-04 Allergan, Inc. Stable suspension formulations of bioerodible polymer matrix microparticles incorporating drug loaded ion exchange resin particles
US5431922A (en) * 1991-03-05 1995-07-11 Bristol-Myers Squibb Company Method for administration of buspirone
US5242428A (en) 1991-10-04 1993-09-07 Aubrey Palestrant Apparatus for wetting hydrophilic-coated guide wires and catheters
US5286493A (en) * 1992-01-27 1994-02-15 Euroceltique, S.A. Stabilized controlled release formulations having acrylic polymer coating
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5273760A (en) * 1991-12-24 1993-12-28 Euroceltigue, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
NZ246748A (en) 1991-12-27 1999-05-28 Kos Pharma Inc Migraine-preventing medicaments comprising a mast cell degranulation blocking agent (e.g. hydroxyzine, ketotifen, azatadine, azelastine, cyproheptadine, oxatomide, terfenadine, etc)
US7070806B2 (en) * 1992-01-27 2006-07-04 Purdue Pharma Lp Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5322073A (en) 1992-01-30 1994-06-21 Sandoz Ltd. Feeding tube retaining strap
US5272137A (en) * 1992-02-14 1993-12-21 Mcneil-Pfc, Inc. Aqueous pharmaceutical suspension for pharmaceutical actives
JP3207494B2 (ja) 1992-04-02 2001-09-10 ロート製薬株式会社 水性懸濁製剤
JP3278192B2 (ja) 1992-04-03 2002-04-30 ロート製薬株式会社 徐放性液剤
US5260068A (en) 1992-05-04 1993-11-09 Anda Sr Pharmaceuticals Inc. Multiparticulate pulsatile drug delivery system
DE4319649A1 (de) * 1993-03-18 1994-09-22 Asta Medica Ag Feste Flupirtin enthaltende orale Darreichungsformen mit kontrollierter Wirkstoffabgabe
NZ260408A (en) * 1993-05-10 1996-05-28 Euro Celtique Sa Controlled release preparation comprising tramadol
JP2916978B2 (ja) 1993-08-25 1999-07-05 エスエス製薬株式会社 放出開始制御型製剤
US5411745A (en) 1994-05-25 1995-05-02 Euro-Celtique, S.A. Powder-layered morphine sulfate formulations
MX9700850A (es) 1995-06-09 1997-09-30 Euro Celtique Sa Formulaciones y metodos para proporcionar anestesia local prolongada.
GB9514451D0 (en) 1995-07-14 1995-09-13 Chiroscience Ltd Sustained-release formulation
ES2144264T3 (es) * 1995-08-29 2000-06-01 Exxon Chemical Patents Inc Polipropileno tolerante a la radiacion y sus articulos utiles.
US6355656B1 (en) 1995-12-04 2002-03-12 Celgene Corporation Phenidate drug formulations having diminished abuse potential
US5837284A (en) 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
US5908850A (en) 1995-12-04 1999-06-01 Celgene Corporation Method of treating attention deficit disorders with d-threo methylphenidate
US6486177B2 (en) 1995-12-04 2002-11-26 Celgene Corporation Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate
JPH09323180A (ja) 1996-06-04 1997-12-16 Asahi Optical Co Ltd スケーリング補正機能を持つレーザ描画装置
ES2262174T3 (es) 1996-09-30 2006-11-16 Alza Corporation Forma de dosificacion y procedimiento de administracion de medicamentos.
CN1179450A (zh) * 1996-10-15 1998-04-22 罗姆和哈斯公司 含有离子交换树脂的涂料组合物
US6919373B1 (en) * 1996-11-12 2005-07-19 Alza Corporation Methods and devices for providing prolonged drug therapy
US5900882A (en) 1996-11-15 1999-05-04 Samsung Electronics Co., Ltd. Determining texture coordinates in computer graphics
ATE406872T1 (de) 1996-12-20 2008-09-15 Mcneil Ppc Inc Durch ionenaustauscherharze verabreichte hustenmittel
DE19709663A1 (de) 1997-03-10 1998-09-17 Basf Ag Verwendung von redispergierbaren Polymerpulvern oder Polymergranulaten als Bindemittel zur Herstellung von festen pharmazeutischen Darreichungsformen
DE19709532A1 (de) * 1997-03-10 1998-09-17 Basf Ag Verwendung von redispergierbaren Polymerpulvern oder Polymergranulaten zum Überziehen von pharmazeutischen oder agrochemischen Darreichungsformen
US5980882A (en) * 1997-04-16 1999-11-09 Medeva Pharmaceuticals Manufacturing Drug-resin complexes stabilized by chelating agents
GB9707934D0 (en) * 1997-04-18 1997-06-04 Danbiosyst Uk Improved delivery of drugs to mucosal surfaces
US6210710B1 (en) 1997-04-28 2001-04-03 Hercules Incorporated Sustained release polymer blend for pharmaceutical applications
DE19732903A1 (de) * 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
EP1041988A4 (en) * 1997-12-22 2002-03-13 Euro Celtique Sa METHOD FOR PREVENTING ABUSE OF OPIOID DOSES FORMS
EP0943341A1 (en) 1998-02-18 1999-09-22 Oscar Gold Procedure to prepare granulated compositions that contain erythromycin macrolides and procedure to prepare pharmaceutical compositions that contain said macrolides
IT1304271B1 (it) 1998-03-17 2001-03-13 Tecno 5 S R L Gruppo serigrafico polifunzionale per macchine a giostra per la stampa serigrafica a piu' colori di contenitori con superfici curve.
US6905707B2 (en) * 1998-05-28 2005-06-14 Medical Research Institute Controlled release arginine alpha ketoglutarate
US20010055613A1 (en) 1998-10-21 2001-12-27 Beth A. Burnside Oral pulsed dose drug delivery system
CA2348871C (en) 1998-11-02 2009-04-14 John G. Devane Multiparticulate modified release composition
US20070160675A1 (en) 1998-11-02 2007-07-12 Elan Corporation, Plc Nanoparticulate and controlled release compositions comprising a cephalosporin
US20060240105A1 (en) 1998-11-02 2006-10-26 Elan Corporation, Plc Multiparticulate modified release composition
EP1135150B1 (en) * 1998-12-11 2012-10-17 Tris Pharma, Inc. Self-emulsifying compositions for drugs poorly soluble in water
US7083808B2 (en) 1998-12-17 2006-08-01 Euro-Celtique S.A. Controlled/modified release oral methylphenidate formulations
US6673367B1 (en) 1998-12-17 2004-01-06 Euro-Celtique, S.A. Controlled/modified release oral methylphenidate formulations
US6419960B1 (en) * 1998-12-17 2002-07-16 Euro-Celtique S.A. Controlled release formulations having rapid onset and rapid decline of effective plasma drug concentrations
WO2000040224A1 (en) * 1999-01-07 2000-07-13 Elan Corporation, Plc Multiparticulate oral dosage forms
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
WO2000059479A1 (en) 1999-04-06 2000-10-12 Pharmaquest Ltd. Pharmaceutical dosage form for pulsatile delivery of methylphenidate
DE19927689A1 (de) * 1999-06-17 2000-12-21 Gruenenthal Gmbh Orale Darreichungsformen zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac
US6384020B1 (en) 1999-07-14 2002-05-07 Shire Laboratories, Inc. Rapid immediate release oral dosage form
WO2001008661A2 (en) * 1999-07-29 2001-02-08 Roxane Laboratories, Inc. Opioid sustained-released formulation
DE19961897A1 (de) * 1999-12-20 2001-06-28 Basf Ag Verwendung eines Filmüberzuges als geschmacksmaskierendes Coating von pharmazeutischen Darreichungsformen
ATE312595T1 (de) 2000-01-19 2005-12-15 Mannkind Corp Formulierung mit mehrfach gepulster wirkstofffreisetzung
DE60138706D1 (de) * 2000-02-08 2009-06-25 Euro Celtique Sa Missbrauchssichere orale opioid-agonist zubereitungen
US6322011B1 (en) 2000-03-14 2001-11-27 Illinois Tool Works Inc. Electrostatic coating system and dual lip bell cup therefor
US7067116B1 (en) * 2000-03-23 2006-06-27 Warner-Lambert Company Llc Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
DE10015479A1 (de) 2000-03-29 2001-10-11 Basf Ag Feste orale Darreichungsformen mit retardierter Wirkstofffreisetzung und hoher mechanischer Stabilität
SE0001151D0 (sv) 2000-03-31 2000-03-31 Amarin Dev Ab Method for producing a controlled-release composition
US6670058B2 (en) * 2000-04-05 2003-12-30 University Of Central Florida Thermocatalytic process for CO2-free production of hydrogen and carbon from hydrocarbons
US6551617B1 (en) * 2000-04-20 2003-04-22 Bristol-Myers Squibb Company Taste masking coating composition
US6419954B1 (en) * 2000-05-19 2002-07-16 Yamanouchi Pharmaceutical Co., Ltd. Tablets and methods for modified release of hydrophilic and other active agents
JP3380536B2 (ja) 2000-08-25 2003-02-24 日本圧着端子製造株式会社 圧接コネクタの受取装置及びこれを備えた自動圧接機
IL145106A0 (en) * 2000-08-30 2002-06-30 Pfizer Prod Inc Intermittent administration of a geowth hormone secretagogue
US6344215B1 (en) 2000-10-27 2002-02-05 Eurand America, Inc. Methylphenidate modified release formulations
GB0030460D0 (en) 2000-12-14 2001-01-24 Isis Innovation Drug delivery system
DE10108122A1 (de) * 2001-02-21 2002-10-02 Gruenenthal Gmbh Arzneimittel auf Basis von Tramadol
DE60212475T2 (de) * 2001-03-14 2007-07-05 Pfizer Products Inc., Groton Pharmazeutische Tablette und ein Verfahren zu ihrer Herstellung
EP1250937B1 (en) * 2001-04-09 2009-05-13 Rohm And Haas Company Controlled dissolution of active ingredients
WO2002092059A1 (en) * 2001-05-11 2002-11-21 Endo Pharmaceuticals, Inc. Abuse-resistant opioid dosage form
EP1277896A1 (en) 2001-07-16 2003-01-22 Ulf Palmberg Floorboards
US7144587B2 (en) * 2001-08-06 2006-12-05 Euro-Celtique S.A. Pharmaceutical formulation containing opioid agonist, opioid antagonist and bittering agent
EP1429728A1 (en) 2001-08-29 2004-06-23 SRL Technologies, Inc. Sustained release preparations
WO2003025520A1 (en) 2001-09-12 2003-03-27 Anthony Charles Lammond Wass Improved liquid dosing device
ES2392960T3 (es) * 2001-10-17 2012-12-17 Takeda Pharmaceutical Company Limited Gránulos que contienen gran cantidad de compuesto químico inestable en medio ácido
US20040126428A1 (en) * 2001-11-02 2004-07-01 Lyn Hughes Pharmaceutical formulation including a resinate and an aversive agent
US7700561B2 (en) 2002-02-22 2010-04-20 Shire Llc Abuse-resistant amphetamine prodrugs
DE10211289A1 (de) * 2002-03-14 2003-09-25 Basf Ag Kombination von Polyvinylacetat von wasserunlöslichen, säureunlöslichen oder alkaliunlöslichen Polymeren zur Hestellung von Filmüberzügen mit sehr kontrollierter Freisetzung und hoher Stabilität
EP1492511B3 (fr) 2002-04-09 2012-05-02 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s)
US7125563B2 (en) * 2002-04-12 2006-10-24 Dava Pharmaceuticals, Inc. Sustained release pharmaceutical preparations and methods for producing the same
US6939029B1 (en) * 2002-05-28 2005-09-06 Kuryakyn Holdings, Inc. Modular light assembly for decorative lights
DE60330780D1 (de) 2002-06-05 2010-02-11 Opexa Pharmaceuticals Inc Sequenzen des t-zellrezeptors cdr3 und nachweisverfahren
JP2006504651A (ja) 2002-07-16 2006-02-09 アミュラ テラピューティクス リミテッド 生物活性化合物
US8268352B2 (en) 2002-08-05 2012-09-18 Torrent Pharmaceuticals Limited Modified release composition for highly soluble drugs
US8216609B2 (en) * 2002-08-05 2012-07-10 Torrent Pharmaceuticals Limited Modified release composition of highly soluble drugs
US20060240128A1 (en) 2002-09-09 2006-10-26 Schlagheck Thomas G Combined immediate release and extended release analgesic composition
US6913768B2 (en) * 2002-09-24 2005-07-05 Shire Laboratories, Inc. Sustained release delivery of amphetamine salts
AU2002342579A1 (en) 2002-09-24 2004-04-19 Gumlink A/S Chewing gum having improved release of chewing gum ingredients
US20060018972A1 (en) * 2002-11-26 2006-01-26 Upm Pharmaceuticals, Inc. Aqueous sustained-release drug delivery system for highly water-soluble electrolytic drugs
JP4808405B2 (ja) 2002-11-26 2011-11-02 ホ−レンベック ギャリ− ア−ル 高度に水溶性の電解質薬剤のための水性徐放性ドラッグデリバリーシステム
FR2848564B1 (fr) * 2002-12-13 2006-12-01 Inst Rech Developpement Ird Souches bacteriennes du genre exiguobacterium, procede de culture et applications
CA2511540A1 (en) * 2002-12-23 2004-07-22 Celltech Americas, Inc. Acid labile drug compositions
JP2006515320A (ja) * 2002-12-31 2006-05-25 ラリー エル オーグスバーガー 活性クッション性成分を含有する医薬品剤形の製造方法
US6780126B2 (en) * 2003-01-02 2004-08-24 Acushnet Company Golf ball with large inner core
US20040228830A1 (en) 2003-01-28 2004-11-18 Collegium Pharmaceutical, Inc. Multiparticulate compositions of milnacipran for oral administration
CH712083B1 (de) 2003-02-05 2017-07-31 Siegfried Ag Verfahren zur Herstellung von d-threo-2-Phenyl-2-piperidin-2-yl-essigsäureestern.
DE602004008771T2 (de) 2003-02-10 2008-06-12 Shire Canada Inc., St. Laurent Enantiomere amphetamine enthaltende zusammensetzungen zur behandlung von aufmerksamkeitsdefizit-/hyperaktivitätsstörung (adhd)
AU2004238321B2 (en) * 2003-05-07 2009-08-27 Samyang Biopharmaceuticals Corporation Highly plastic granules for making fast melting tablets
US20060115529A1 (en) * 2003-05-07 2006-06-01 Seonghoon Jeong Fast-melting tablets having taste-masking and sustained release properties
US6997219B2 (en) 2003-05-12 2006-02-14 Medical Instill Technologies, Inc. Dispenser and apparatus and method for filling a dispenser
US20040259809A1 (en) 2003-06-17 2004-12-23 Pediamed Pharmaceuticals, Inc. Pharmaceutical compositions including an antihistamine and a stimulant and method of use thereof
US20050036977A1 (en) * 2003-08-11 2005-02-17 Dilip Gole Taste-masked resinate and preparation thereof
CN1845722A (zh) * 2003-09-03 2006-10-11 马林克罗特公司 粒状缓释制剂及其生产
MXPA06003725A (es) 2003-10-08 2006-06-23 Mallinckrodt Inc Solucion de fenidato de metilo y metodos asociados de administracion y produccion.
US20050220881A1 (en) 2003-10-10 2005-10-06 Bvm Holding Co. Pharmaceutical composition
US20060029664A1 (en) * 2004-08-04 2006-02-09 Sovereign Pharmaceuticals, Ltd. Dosage form containing carbetapentane and another drug
US20050232986A1 (en) * 2003-12-17 2005-10-20 David Brown Dosage form containing promethazine and another drug
US20050232987A1 (en) * 2004-03-12 2005-10-20 Viswanathan Srinivasan Dosage form containing a morphine derivative and another drug
US20050266032A1 (en) * 2003-12-17 2005-12-01 Sovereign Pharmaceuticals, Ltd. Dosage form containing multiple drugs
US9492541B2 (en) * 2004-09-14 2016-11-15 Sovereign Pharmaceuticals, Llc Phenylepherine containing dosage form
US20050142097A1 (en) 2003-12-29 2005-06-30 Deepak Thassu Multiple active drug resin conjugate
US20050181050A1 (en) 2004-01-28 2005-08-18 Collegium Pharmaceutical, Inc. Dosage forms using drug-loaded ion exchange resins
JP2005306778A (ja) 2004-04-21 2005-11-04 Basf Ag 徐放性製剤及びその製造方法
US20050266031A1 (en) 2004-05-25 2005-12-01 Jay Dickerson Pharmaceutical suspension composition
US20050265955A1 (en) * 2004-05-28 2005-12-01 Mallinckrodt Inc. Sustained release preparations
US9592197B2 (en) * 2004-12-16 2017-03-14 Sovereign Pharmaceuticals, Llc Dosage form containing diphenhydramine and another drug
WO2006022996A2 (en) 2004-08-04 2006-03-02 Sovereign Pharmaceuticals, Ltd. Dosage form containing multiple drugs
DK1791530T3 (da) 2004-08-23 2008-10-27 Pejo Iserlohn Heilmittel Und D Farmaceutisk komposition indeholdende et psykostimulerende middel
EP1809259B1 (en) 2004-10-15 2014-12-03 Supernus Pharmaceuticals, Inc. Less abusable pharmaceutical preparations
US7173497B1 (en) * 2004-11-05 2007-02-06 Rockwell Collins, Inc. Sampling voltage controlled oscillator
US20080095842A1 (en) 2004-12-06 2008-04-24 Antarkar Amit K Rapidly Disintegrating Taste Masked Compositions and a Process for Its Preparations
US8318210B2 (en) 2005-02-28 2012-11-27 Neos Therapeutics, Lp Compositions and methods of making sustained release liquid formulations
US7276794B2 (en) 2005-03-02 2007-10-02 Endevco Corporation Junction-isolated vias
EP1893175A1 (en) 2005-06-09 2008-03-05 Upm Pharmaceuticals, Inc. Aqueous sustained-release drug delivery system for highly water-soluble electrolytic drugs
JP2008546835A (ja) 2005-06-28 2008-12-25 ユ セ ベ ソシエテ アノニム 複数の活性薬物−樹脂抱合体
BRPI0613070A2 (pt) 2005-06-29 2010-12-21 Panacea Biotec Ltd composições farmacêuticas de liberação sustentada e seus processos
US8343546B2 (en) 2005-09-13 2013-01-01 Coating Place, Inc. Ion exchange resin treated to control swelling
FR2891459B1 (fr) 2005-09-30 2007-12-28 Flamel Technologies Sa Microparticules a liberation modifiee d'au moins un principe actif et forme galenique orale en comprenant
US20070092553A1 (en) 2005-10-21 2007-04-26 Pfab Lp Compositions and methods of making rapidly dissolving lonically masked formulations
WO2007100777A2 (en) 2006-02-28 2007-09-07 The Mclean Hospital Corporation Methods for the treatment of adhd and related disorders
CA2645855C (en) 2006-03-16 2015-02-03 Tris Pharma, Inc. Modified release formulations containing drug-ion exchange resin complexes
US8846100B2 (en) 2006-05-12 2014-09-30 Shire Llc Controlled dose drug delivery system
US20080064694A1 (en) 2006-09-11 2008-03-13 Auriga Laboratories, Inc. Multi-Phase Release Methscopolamine Compositions
US8287848B2 (en) 2006-10-03 2012-10-16 Tris Pharma Inc Formulations containing an ionic mineral-ion exchange resin complex and uses thereof
US20080118570A1 (en) 2006-11-20 2008-05-22 Zhi Liu Polymer coated drug-ion exchange resins and methods
WO2008064192A2 (en) 2006-11-21 2008-05-29 Mcneil-Ppc, Inc. Modified release analgesic suspensions
ES2364865T3 (es) 2006-12-11 2011-09-15 Kempharm, Inc. Conjugados de ornitina de la anfetamina y procedimientos de fabricación y de utilización de los mismos.
US20100104621A1 (en) 2007-02-21 2010-04-29 Connected Health Systems, Llc Treating adhd and other diseases involving inflammation
US8313770B2 (en) 2007-05-30 2012-11-20 Neos Therapeutics, Lp Modifying drug release in suspensions of ionic resin systems
US8202542B1 (en) 2007-05-31 2012-06-19 Tris Pharma Abuse resistant opioid drug-ion exchange resin complexes having hybrid coatings
JP5279246B2 (ja) 2007-12-05 2013-09-04 京セラドキュメントソリューションズ株式会社 画像形成装置および印刷システム
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
WO2010080787A1 (en) 2009-01-09 2010-07-15 Mallinckrodt Inc. Synthesis of methylphenidate and analogs thereof
EP3311667A1 (en) 2009-07-08 2018-04-25 Charleston Laboratories, Inc. Pharmaceutical compositions
US8470375B1 (en) 2010-01-05 2013-06-25 Neos Therapeutics, Lp Method of formulating and designing liquid drug suspensions containing ion exchange resin particles
GB201002612D0 (en) 2010-02-16 2010-03-31 Jagotec Ag Improvements in or relating to organic compounds
EP2549986B1 (en) 2010-03-24 2019-10-30 Northeastern University Multi-compartmental macrophage delivery
US8623409B1 (en) 2010-10-20 2014-01-07 Tris Pharma Inc. Clonidine formulation
US8287903B2 (en) 2011-02-15 2012-10-16 Tris Pharma Inc Orally effective methylphenidate extended release powder and aqueous suspension product
EP2675438B1 (en) 2011-02-15 2019-04-10 Tris Pharma, Inc. Extended release powder and aqueous suspension comprising methylphenidate
EP2726066B1 (en) 2011-06-28 2021-03-31 Neos Therapeutics, LP Dosage forms of amphetamine for oral administration
US20140214431A1 (en) 2011-07-01 2014-07-31 Dolby Laboratories Licensing Corporation Sample rate scalable lossless audio coding
CA2758556A1 (en) 2011-11-17 2013-05-17 Pharmascience Inc. Pharmaceutical composition of amphetamine mixed salts
DK2884961T3 (en) 2012-08-15 2019-04-23 Tris Pharma Inc METHYLPHENIDATE TABLE WITH EXTENDED RELEASE
WO2014058742A1 (en) 2012-10-09 2014-04-17 Sears Douglas Therapeutic treatment
US9180104B2 (en) 2013-03-13 2015-11-10 Tris Pharma, Inc. Benzonatate modified release solid tablets and capsules

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