JP2009526034A5 - - Google Patents
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- JP2009526034A5 JP2009526034A5 JP2008553834A JP2008553834A JP2009526034A5 JP 2009526034 A5 JP2009526034 A5 JP 2009526034A5 JP 2008553834 A JP2008553834 A JP 2008553834A JP 2008553834 A JP2008553834 A JP 2008553834A JP 2009526034 A5 JP2009526034 A5 JP 2009526034A5
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- JP
- Japan
- Prior art keywords
- optionally substituted
- aryl
- represent
- hydrogen
- different
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 125000003118 aryl group Chemical group 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 239000001257 hydrogen Substances 0.000 claims 3
- 206010013801 Duchenne Muscular Dystrophy Diseases 0.000 claims 2
- 125000003435 aroyl group Chemical group 0.000 claims 2
- 125000001589 carboacyl group Chemical group 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 150000002431 hydrogen Chemical class 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 125000001424 substituent group Chemical group 0.000 claims 2
- 229910052717 sulfur Inorganic materials 0.000 claims 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000004104 aryloxy group Chemical group 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 125000005647 linker group Chemical group 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000011321 prophylaxis Methods 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 125000005415 substituted alkoxy group Chemical group 0.000 claims 1
- 125000000547 substituted alkyl group Chemical group 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0602768.4 | 2006-02-10 | ||
| GB0602768A GB0602768D0 (en) | 2006-02-10 | 2006-02-10 | Treatment of muscular dystrophy |
| GB0614690.6 | 2006-07-24 | ||
| GB0614690A GB0614690D0 (en) | 2006-07-24 | 2006-07-24 | Method of treatment of duchenne muscular dystrophy |
| GB0619281.9 | 2006-09-29 | ||
| GB0619281A GB0619281D0 (en) | 2006-09-29 | 2006-09-29 | Treatment of duchenne muscular dystrophy |
| GB0623983A GB0623983D0 (en) | 2006-11-30 | 2006-11-30 | Treatment of duchenne muscular dystrophy |
| GB0623983.4 | 2006-11-30 | ||
| PCT/GB2007/050055 WO2007091106A2 (en) | 2006-02-10 | 2007-02-09 | Treatment of duchenne muscular dystrophy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009526034A JP2009526034A (ja) | 2009-07-16 |
| JP2009526034A5 true JP2009526034A5 (cg-RX-API-DMAC10.html) | 2010-03-04 |
| JP5376956B2 JP5376956B2 (ja) | 2013-12-25 |
Family
ID=38229987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008553834A Expired - Fee Related JP5376956B2 (ja) | 2006-02-10 | 2007-02-09 | デュシェンヌ型筋ジストロフィーの治療 |
Country Status (17)
Families Citing this family (70)
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| TWI652014B (zh) | 2013-09-13 | 2019-03-01 | 美商艾佛艾姆希公司 | 雜環取代之雙環唑殺蟲劑 |
| RU2681537C2 (ru) * | 2014-04-14 | 2019-03-07 | Шанхай Хэнжуй Фармасьютикал Ко., Лтд. | Амидные производные и их фармацевтически приемлемые соли, способ их получения и медицинское применение |
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| CN119816500A (zh) | 2021-08-20 | 2025-04-11 | 拜欧米富士恩公司 | 用于治疗癌症的不可逆menin-MLL抑制剂N-[4-[4-(4-吗啉基)-7H-吡咯并[2,3-d]嘧啶-6-基]苯基]-4-[[3(R)-[(1-氧代-2-丙烯-1-基)氨基]-1-哌啶基]甲基]-2-吡啶甲酰胺的结晶形式 |
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