|
JP5442449B2
(ja)
|
2006-12-22 |
2014-03-12 |
アステックス、セラピューティックス、リミテッド |
新規化合物
|
|
CN101679408B
(zh)
|
2006-12-22 |
2016-04-27 |
Astex治疗学有限公司 |
作为fgfr抑制剂的双环杂环化合物
|
|
CA2691987C
(en)
*
|
2007-06-12 |
2016-08-16 |
Achaogen, Inc. |
Antibacterial agents
|
|
GB0720038D0
(en)
|
2007-10-12 |
2007-11-21 |
Astex Therapeutics Ltd |
New compounds
|
|
GB0720041D0
(en)
|
2007-10-12 |
2007-11-21 |
Astex Therapeutics Ltd |
New Compounds
|
|
US20110092554A1
(en)
*
|
2007-11-19 |
2011-04-21 |
Richard Chesworth |
1,3,5 tri-subtituted benzenes for treatment of alzheimer's disease and other disorders
|
|
WO2009086277A1
(en)
|
2007-12-20 |
2009-07-09 |
Envivo Pharmaceuticals, Inc. |
Tetrasubstituted benzenes
|
|
EP2257536A4
(en)
|
2008-02-14 |
2011-03-23 |
Amira Pharmaceuticals Inc |
CYCLIC DIARYL ETHERS AS ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS
|
|
US8426449B2
(en)
|
2008-04-02 |
2013-04-23 |
Panmira Pharmaceuticals, Llc |
Aminoalkylphenyl antagonists of prostaglandin D2 receptors
|
|
UA103319C2
(en)
|
2008-05-06 |
2013-10-10 |
Глаксосмитклайн Ллк |
Thiazole- and oxazole-benzene sulfonamide compounds
|
|
GB0810902D0
(en)
|
2008-06-13 |
2008-07-23 |
Astex Therapeutics Ltd |
New compounds
|
|
US20110212078A1
(en)
*
|
2008-06-25 |
2011-09-01 |
Reddy Panduranga Adulla P |
Synthesis and use of heterocyclic antibacterial agents
|
|
MX2010014172A
(es)
|
2008-07-03 |
2011-02-22 |
Amira Pharmaceuticals Inc |
Antagonistas de receptores de prostaglandina d2.
|
|
US8273900B2
(en)
|
2008-08-07 |
2012-09-25 |
Novartis Ag |
Organic compounds
|
|
US8372885B2
(en)
*
|
2008-09-17 |
2013-02-12 |
Novartis Ag |
Organic compounds and their uses
|
|
US8383654B2
(en)
|
2008-11-17 |
2013-02-26 |
Panmira Pharmaceuticals, Llc |
Heterocyclic antagonists of prostaglandin D2 receptors
|
|
GB0906472D0
(en)
|
2009-04-15 |
2009-05-20 |
Astex Therapeutics Ltd |
New compounds
|
|
GB0906470D0
(en)
|
2009-04-15 |
2009-05-20 |
Astex Therapeutics Ltd |
New compounds
|
|
WO2011005355A1
(en)
*
|
2009-05-07 |
2011-01-13 |
Achaogen, Inc. |
Combinations comprising a lpxc inhibitor and an antibiotic for use in the treatment of infections caused by gram-negative bacteria
|
|
FR2950056B1
(fr)
|
2009-09-17 |
2011-08-26 |
Galderma Res & Dev |
Nouveaux composes benzene-carboxylamides, leur procede de synthese et leur utilisation en medecine ainsi qu'en cosmetique
|
|
FR2950057B1
(fr)
|
2009-09-17 |
2011-08-26 |
Galderma Res & Dev |
Nouveaux composes benzene-carboxylamides, leur procede de synthese et leur utilisation en medecine ainsi qu'en cosmetique
|
|
EP3406613A1
(en)
|
2009-10-16 |
2018-11-28 |
Melinta Therapeutics, Inc. |
Antimicrobial compounds and methods of making and using the same
|
|
JP6274723B2
(ja)
|
2009-10-16 |
2018-02-07 |
メリンタ セラピューティクス,インコーポレイテッド |
抗微生物性化合物および抗微生物性化合物の製造方法および使用方法
|
|
JP2013508299A
(ja)
|
2009-10-16 |
2013-03-07 |
リブ−エックス ファーマシューティカルズ,インコーポレイテッド |
抗微生物性化合物および抗微生物性化合物の製造方法および使用方法
|
|
MX2012007927A
(es)
|
2010-01-06 |
2012-08-15 |
Panmira Pharmaceuticals Llc |
Antagonistas de dp2 y usos del mismo.
|
|
RS59255B1
(sr)
|
2010-04-20 |
2019-10-31 |
Fujifilm Toyama Chemical Co Ltd |
Derivat hidroksaminske kiseline
|
|
US8835472B2
(en)
*
|
2010-09-02 |
2014-09-16 |
Boehringer Ingelheim International Gmbh |
Compounds, pharmaceutical compositions and uses thereof
|
|
US9738604B2
(en)
|
2010-09-03 |
2017-08-22 |
Duke University |
Ethynylbenzene derivatives
|
|
EP2638006A1
(en)
|
2010-11-10 |
2013-09-18 |
Achaogen, Inc. |
Hydroxamic acid derivatives and their use in the treatment of bacterial infections
|
|
EP3404028A1
(en)
|
2011-04-15 |
2018-11-21 |
Melinta Therapeutics, Inc. |
Methods of making antimicrobial compounds
|
|
US8883819B2
(en)
|
2011-09-01 |
2014-11-11 |
Irm Llc |
Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension
|
|
US20150203444A1
(en)
|
2011-09-12 |
2015-07-23 |
Achaogen, Inc. |
Polymorphs of n-((s)-3-amino-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl)-4-(((1r,2r)-2-(hydroxymethyl)cyclopropyl)buta-1,3-diynyl)benzamide
|
|
CN102603690A
(zh)
*
|
2012-01-17 |
2012-07-25 |
凯莱英医药集团(天津)股份有限公司 |
一种一锅法制备四氢吡喃-4-甲酸及其衍生物的方法
|
|
UA116534C2
(uk)
|
2012-02-17 |
2018-04-10 |
Мілленніум Фармасьютікалз, Інк. |
Піразолопіримідинілові інгібітори убіквітинактивуючого ферменту
|
|
EP2847162A1
(en)
*
|
2012-05-09 |
2015-03-18 |
Achaogen, Inc. |
Antibacterial agents
|
|
WO2013170165A1
(en)
|
2012-05-10 |
2013-11-14 |
Achaogen, Inc. |
Antibacterial agents
|
|
JP6139272B2
(ja)
*
|
2012-06-01 |
2017-05-31 |
株式会社半導体エネルギー研究所 |
発光素子の作製方法
|
|
US9073921B2
(en)
|
2013-03-01 |
2015-07-07 |
Novartis Ag |
Salt forms of bicyclic heterocyclic derivatives
|
|
WO2014165075A1
(en)
|
2013-03-12 |
2014-10-09 |
Achaogen, Inc. |
Antibacterial agents
|
|
EP2975022B1
(en)
|
2013-03-15 |
2019-05-08 |
FUJIFILM Toyama Chemical Co., Ltd. |
Novel hydroxamic acid derivative or salt thereof
|
|
GB201307233D0
(en)
*
|
2013-04-22 |
2013-05-29 |
Vib Vzw |
Compounds and uses thereof
|
|
WO2015002994A2
(en)
|
2013-07-02 |
2015-01-08 |
Millennium Pharmaceuticals, Inc. |
Heteroaryl compounds useful as inhibitors of sumo activating enzyme
|
|
WO2015024016A2
(en)
|
2013-08-16 |
2015-02-19 |
Duke University |
2-piperidinyl substituted n,3-dihydroxybutanamides
|
|
WO2015024011A2
(en)
|
2013-08-16 |
2015-02-19 |
Duke University |
Antibacterial compounds
|
|
AU2014306451B2
(en)
|
2013-08-16 |
2019-01-17 |
Duke University |
Substituted hydroxamic acid compounds
|
|
US9937183B2
(en)
|
2013-09-09 |
2018-04-10 |
Melinta Therapeutics, Inc. |
Antimicrobial compounds and methods of making and using the same
|
|
MX2016002975A
(es)
|
2013-09-09 |
2016-10-21 |
Melinta Therapeutics Inc |
Compuestos antimicrobianos y métodos de fabricación y utilización de los mismos.
|
|
AR097617A1
(es)
|
2013-09-13 |
2016-04-06 |
Actelion Pharmaceuticals Ltd |
Derivados antibacterianos del 2h-indazol
|
|
JP2016210683A
(ja)
*
|
2013-10-18 |
2016-12-15 |
大正製薬株式会社 |
ヒドロキサム酸誘導体
|
|
JP2016210682A
(ja)
*
|
2013-10-18 |
2016-12-15 |
大正製薬株式会社 |
ヒドロキサム酸誘導体
|
|
WO2015056799A1
(ja)
*
|
2013-10-18 |
2015-04-23 |
大正製薬株式会社 |
ヒドロキサム酸誘導体
|
|
KR20160098503A
(ko)
|
2013-12-19 |
2016-08-18 |
액테리온 파마슈티칼 리미티드 |
항균성 1h-인다졸 및 1h-인돌 유도체
|
|
US9539305B1
(en)
|
2014-03-14 |
2017-01-10 |
Fleurir Abx Llc |
Pristinamycin compositions, LpxC compositions, their improvements, and combinations thereof
|
|
WO2015173329A1
(en)
*
|
2014-05-16 |
2015-11-19 |
Actelion Pharmaceuticals Ltd |
Antibacterial quinazoline-4(3h)-one derivatives
|
|
MX388409B
(es)
*
|
2014-06-12 |
2025-03-19 |
Cedars Sinai Medical Center |
Composiciones y metodos para tratar canceres.
|
|
BR112016030787B1
(pt)
|
2014-07-01 |
2022-12-20 |
Takeda Pharmaceutical Company Limited |
Entidade química, composição farmacêutica e seu uso
|
|
CN106794162A
(zh)
|
2014-09-12 |
2017-05-31 |
富山化学工业株式会社 |
组合使用新的异羟肟酸衍生物和抗菌性物质的方法
|
|
CA2960949A1
(en)
|
2014-09-12 |
2016-03-17 |
Tatsuya Honda |
Novel pharmaceutical composition containing hydroxamic acid derivative or salt thereof
|
|
CN104341475A
(zh)
*
|
2014-10-11 |
2015-02-11 |
吉首大学 |
利奈唑胺-腺苷型多靶点抗菌化合物及其制法和用途
|
|
CN104327140B
(zh)
*
|
2014-10-11 |
2016-06-15 |
吉首大学 |
噁唑烷酮-腺苷型多靶点抗菌化合物及其制法和用途
|
|
CN104231024B
(zh)
*
|
2014-10-11 |
2016-06-15 |
吉首大学 |
噁二唑-肌苷型化合物作为TyrRS抑制剂及其制法和用途
|
|
CN104341476A
(zh)
*
|
2014-10-11 |
2015-02-11 |
吉首大学 |
利奈唑胺-肌苷型多靶点抗菌化合物及其制法和用途
|
|
CN104262433B
(zh)
*
|
2014-10-11 |
2016-06-15 |
吉首大学 |
噁二唑-腺苷型化合物作为TyrRS抑制剂及其制法和用途
|
|
CN105777464B
(zh)
*
|
2014-12-26 |
2020-09-29 |
中国科学院上海药物研究所 |
异羟肟酸衍生物及其制备方法和应用
|
|
JP6208161B2
(ja)
|
2015-02-06 |
2017-10-04 |
信越化学工業株式会社 |
非対称共役ジイン化合物の製造方法及びこれを用いたz,z−共役ジエン化合物の製造方法
|
|
WO2016145417A1
(en)
|
2015-03-11 |
2016-09-15 |
Melinta Therapeutics, Inc. |
Antimicrobial compounds and methods of making and using the same
|
|
EP3374350B1
(en)
|
2015-11-09 |
2022-01-05 |
Forge Therapeutics, Inc. |
Hydroxypyridinone and hydroxypyrimidinone based compounds for treating bacterial infections
|
|
US10611747B2
(en)
|
2015-11-09 |
2020-04-07 |
Forge Therapeutics, Inc. |
Pyrone based compounds for treating bacterial infections
|
|
WO2017098440A1
(en)
*
|
2015-12-08 |
2017-06-15 |
Glaxosmithkline Intellectual Property Development Limited |
Substituted benzazinones as antibacterial compounds
|
|
CN105669750B
(zh)
*
|
2016-03-01 |
2018-04-03 |
中国医学科学院医药生物技术研究所 |
新型锌离子螯合剂及其制备和在抗革兰氏阴性菌感染中的应用
|
|
US10407421B2
(en)
|
2016-03-07 |
2019-09-10 |
Merck Sharp & Dohme Corp |
Bicyclic aryl monobactam compounds and methods of use thereof for the treatment of bacterial infections
|
|
WO2017156071A1
(en)
|
2016-03-09 |
2017-09-14 |
Blade Therapeutics, Inc. |
Cyclic keto-amide compounds as calpain modulators and methods of production and use thereof
|
|
PL3445744T3
(pl)
*
|
2016-04-18 |
2022-02-07 |
Vivoryon Therapeutics Ag |
Nowe inhibitory mepryny alfa i beta
|
|
AU2017257755B2
(en)
*
|
2016-04-25 |
2021-05-06 |
Duke University |
Benzoylglycine derivatives and methods of making and using same
|
|
US11098047B2
(en)
|
2016-05-06 |
2021-08-24 |
BioVersys AG |
Antimicrobials and methods of making and using same
|
|
WO2017223349A1
(en)
|
2016-06-23 |
2017-12-28 |
Achaogen, Inc. |
Antibacterial agents
|
|
AU2017292646A1
(en)
|
2016-07-05 |
2019-02-07 |
Blade Therapeutics, Inc. |
Calpain modulators and therapeutic uses thereof
|
|
US10934261B2
(en)
|
2016-09-28 |
2021-03-02 |
Blade Therapeutics, Inc. |
Calpain modulators and therapeutic uses thereof
|
|
US11034650B2
(en)
*
|
2016-12-23 |
2021-06-15 |
Intervet Inc. |
Compounds useful for treating a Mannheimia haemolytica or Histophilus somni infection
|
|
JP7082445B2
(ja)
|
2016-12-23 |
2022-06-08 |
インターベット インターナショナル ベー. フェー. |
ウシ又はブタの呼吸器疾患を治療するための化合物
|
|
CA3058695A1
(en)
|
2017-04-26 |
2018-11-01 |
Basilea Pharmaceutica International AG |
Processes for the preparation of furazanobenzimidazoles and crystalline forms thereof
|
|
WO2018208987A2
(en)
*
|
2017-05-10 |
2018-11-15 |
Forge Therapeutics, Inc. |
Antibacterial compounds
|
|
EP3621962A4
(en)
|
2017-05-10 |
2020-12-09 |
Forge Therapeutics, Inc. |
ANTIBACTERIAL COMPOUNDS
|
|
US11351126B2
(en)
*
|
2017-07-27 |
2022-06-07 |
BioMendics, LLC |
Substituted tolans for the modulation of microbial colonization
|
|
CN111511723A
(zh)
*
|
2017-08-21 |
2020-08-07 |
米可如比奥提克斯有限公司 |
用作抗菌剂的代谢稳定的n-酰基氨基噁二唑
|
|
KR102868718B1
(ko)
*
|
2018-02-10 |
2025-10-14 |
케이비피 바이오사이언시즈 씨오., 엘티디. |
항생제로서 작용하는 화합물
|
|
CN112135825A
(zh)
|
2018-03-13 |
2020-12-25 |
夏尔人类遗传性治疗公司 |
血浆激肽释放酶抑制剂及其用途
|
|
JP7337174B2
(ja)
|
2018-09-18 |
2023-09-01 |
ニカング セラピューティクス, インコーポレイテッド |
Srcホモロジー-2ホスファターゼ阻害剤としての三置換ヘテロアリール誘導体
|
|
WO2020061375A1
(en)
|
2018-09-20 |
2020-03-26 |
Forge Therapeutics, Inc. |
Antibacterial compounds
|
|
WO2020092394A1
(en)
|
2018-10-30 |
2020-05-07 |
Gilead Sciences, Inc. |
Imidazopyridine derivatives as alpha4beta7 integrin inhibitors
|
|
DK3873884T3
(da)
|
2018-10-30 |
2025-02-17 |
Gilead Sciences Inc |
3-(quinolin-8-yl)-1,4-dihydropyrido[3,4-d]pyrimidin-2,4-dion-derivater som alpha4beta7-integrinhæmmere til behandling af inflammatoriske sygdomme
|
|
ES2987796T3
(es)
|
2018-10-30 |
2024-11-18 |
Gilead Sciences Inc |
Derivados de N-benzoil-fenilalanina como inhibidores de la integrina alfa4beta7 para el tratamiento de enfermedades inflamatorias
|
|
WO2020092401A1
(en)
|
2018-10-30 |
2020-05-07 |
Gilead Sciences, Inc. |
COMPOUNDS FOR INHIBITION OF ALPHA 4β7 INTEGRIN
|
|
US20220081421A1
(en)
*
|
2018-11-14 |
2022-03-17 |
Forge Therapeutics, Inc. |
Antibacterial compounds
|
|
BR112021009536A2
(pt)
*
|
2018-11-21 |
2021-08-17 |
Taisho Pharmaceutical Co., Ltd. |
derivado de imidazol
|
|
AU2020329207B2
(en)
|
2019-08-14 |
2024-02-29 |
Gilead Sciences, Inc. |
Compounds for inhibition of alpha 4 beta 7 integrin
|
|
WO2021055589A1
(en)
|
2019-09-18 |
2021-03-25 |
Shire Human Genetic Therapies, Inc. |
Heteroaryl plasma kallikrein inhibitors
|
|
CN114728962B
(zh)
|
2019-09-18 |
2025-09-19 |
武田药品工业有限公司 |
血浆激肽释放酶抑制剂及其用途
|
|
CN110563611B
(zh)
*
|
2019-09-19 |
2021-02-02 |
中国医学科学院医药生物技术研究所 |
一种异羟肟酸类衍生物及其制备方法和应用
|
|
WO2021138391A1
(en)
|
2019-12-30 |
2021-07-08 |
Tyra Biosciences, Inc. |
Indazole compounds
|
|
WO2021195260A1
(en)
|
2020-03-25 |
2021-09-30 |
Forge Therapeutics, Inc. |
Lpxc inhibitor and methods of making
|
|
BR112022025037A2
(pt)
|
2020-06-10 |
2023-02-14 |
Aligos Therapeutics Inc |
Compostos antivirais para tratar infecções por coronavírus, picornavírus e norovírus
|
|
MX2023014819A
(es)
|
2021-06-14 |
2024-03-21 |
Scorpion Therapeutics Inc |
Derivados de la urea que pueden ser utilizados para tratar el cancer.
|
|
WO2023283256A1
(en)
|
2021-07-09 |
2023-01-12 |
Aligos Therapeutics, Inc. |
Anti-viral compounds
|
|
WO2023011573A1
(zh)
*
|
2021-08-05 |
2023-02-09 |
浙江海正药业股份有限公司 |
芳香乙炔类衍生物及其制备方法和用途
|
|
US12065428B2
(en)
|
2021-09-17 |
2024-08-20 |
Aligos Therapeutics, Inc. |
Anti-viral compounds
|
|
AR127139A1
(es)
|
2021-09-28 |
2023-12-20 |
Forge Therapeutics Inc |
Inhibidores de lpxc y usos de estos
|
|
CA3242454A1
(en)
*
|
2021-12-24 |
2023-06-29 |
Intervet International B.V. |
Process of the preparation of hydroxylamine derivatives
|
|
AU2023303408A1
(en)
|
2022-07-06 |
2024-12-19 |
Aligos Therapeutics, Inc. |
Anti-viral compounds
|
|
WO2024067813A1
(zh)
*
|
2022-09-28 |
2024-04-04 |
浙江海正药业股份有限公司 |
芳香乙炔类衍生物及其制备方法和其医药上的用途
|
|
CN115480037B
(zh)
*
|
2022-10-14 |
2023-07-18 |
青岛国泰检测科技有限公司 |
一种污水检测方法
|
|
CN115598253B
(zh)
*
|
2022-10-25 |
2025-02-21 |
无锡紫杉药业股份有限公司 |
一种多西他赛原料药中dcc和dcu残留的检测方法
|
|
AR131380A1
(es)
|
2022-12-16 |
2025-03-12 |
Astrazeneca Ab |
Purinas 2,6,9-trisustituidas
|
|
CN116730870B
(zh)
|
2023-08-08 |
2023-10-13 |
中国医学科学院医药生物技术研究所 |
异羟肟酸类化合物或其可药用盐、及其用途和制备方法
|
|
CN117586278A
(zh)
*
|
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