JP2009519339A - 筋細胞増殖及び分化を調節するマイクロｒｎａ - Google Patents

筋細胞増殖及び分化を調節するマイクロｒｎａ Download PDF

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JP2009519339A
JP2009519339A JP2008545718A JP2008545718A JP2009519339A JP 2009519339 A JP2009519339 A JP 2009519339A JP 2008545718 A JP2008545718 A JP 2008545718A JP 2008545718 A JP2008545718 A JP 2008545718A JP 2009519339 A JP2009519339 A JP 2009519339A
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mir
mirna
gene
muscle
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ワン ダジ
チェン ジャンフ
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University of North Carolina at Chapel Hill
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JP2008545718A 2005-12-12 2006-12-12 筋細胞増殖及び分化を調節するマイクロｒｎａ Pending JP2009519339A (ja)

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US74954405P 2005-12-12 2005-12-12
PCT/US2006/047255 WO2007070483A2 (en) 2005-12-12 2006-12-12 Micrornas that regulate muscle cell proliferation and differentiation

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JP2013027633A Division JP5796027B2 (ja) 2005-12-12 2013-02-15 筋細胞増殖及び分化を調節するマイクロｒｎａ
JP2013253829A Division JP5740460B2 (ja) 2005-12-12 2013-12-09 筋細胞増殖及び分化を調節するマイクロｒｎａ

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JP2009519339A5 JP2009519339A5 (enExample) 2010-01-14

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JP2013027633A Expired - Fee Related JP5796027B2 (ja) 2005-12-12 2013-02-15 筋細胞増殖及び分化を調節するマイクロｒｎａ
JP2013253829A Expired - Fee Related JP5740460B2 (ja) 2005-12-12 2013-12-09 筋細胞増殖及び分化を調節するマイクロｒｎａ

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JP2013253829A Expired - Fee Related JP5740460B2 (ja) 2005-12-12 2013-12-09 筋細胞増殖及び分化を調節するマイクロｒｎａ

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US (3) US8431542B2 (enExample)
EP (3) EP1969125B1 (enExample)
JP (3) JP2009519339A (enExample)
KR (2) KR101485071B1 (enExample)
CN (2) CN104027818A (enExample)
AU (1) AU2006326517B2 (enExample)
BR (1) BRPI0619755A2 (enExample)
CA (2) CA2634046A1 (enExample)
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NZ (3) NZ602571A (enExample)
PL (1) PL1969125T3 (enExample)
PT (1) PT1969125E (enExample)
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Cited By (8)

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JP2013542921A (ja) * 2010-09-13 2013-11-28 エスエヌユー アールアンドディービー ファウンデーション ｍｉＲＮＡをターゲットとした神経変性疾患の治療
JP2014503192A (ja) * 2010-11-05 2014-02-13 ミラゲン セラピューティクス 塩基修飾オリゴヌクレオチド
WO2018070510A1 (ja) * 2016-10-13 2018-04-19 国立研究開発法人国立精神・神経医療研究センター 筋分化誘導剤
JP2019512489A (ja) * 2016-03-07 2019-05-16 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ マイクロｒｎａおよびその使用方法
JP2020534349A (ja) * 2017-08-18 2020-11-26 クラミス シーオー., エルティーディー.Curamys Co., Ltd. 筋肉疾患および神経筋肉疾患の予防、治療または診断のためのｍｉＲ−１８ｂの用途
JP2021505176A (ja) * 2017-12-08 2021-02-18 ユニバーシティ オブ ワシントンＵｎｉｖｅｒｓｉｔｙ ｏｆ Ｗａｓｈｉｎｇｔｏｎ カルジオリピンのリモデリング及び心筋細胞の成熟を検出、及び促進する方法及び組成物、並びにミトコンドリア機能障害治療の関連する方法
US11597930B2 (en) 2020-04-02 2023-03-07 Mirecule, Inc. Targeted inhibition using engineered oligonucleotides
JP2023515672A (ja) * 2020-03-02 2023-04-13 テナヤ セラピューティクス， インコーポレイテッド 心筋細胞発現マイクロｒｎａによる遺伝子ベクター制御

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* Cited by examiner, † Cited by third party
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US8592384B2 (en) 2005-04-04 2013-11-26 The Board Of Regents Of The University Of Texas System Micro-RNA's that regulate muscle cells
CA2634046A1 (en) 2005-12-12 2007-06-21 The University Of North Carolina At Chapel Hill Micrornas that regulate muscle cell proliferation and differentiation
DK2056882T3 (da) 2006-08-01 2012-11-19 Univ Texas Identifikation af en mikro-rna, som aktiverer ekspression af en tung kæde med beta-myosin
GB2440782A (en) 2006-08-04 2008-02-13 Cesare Peschle Uses and compositions comprising miRNAs
JP2010500011A (ja) 2006-08-08 2010-01-07 ガンサー ハートマン ５’リン酸オリゴヌクレオチドの構造および使用
CA2728571A1 (en) * 2007-06-29 2009-01-08 Boston Biomedical, Inc. Bacteria-mediated gene modulation via microrna machinery
DK2182969T3 (en) 2007-07-31 2017-02-27 Univ Texas Micro-RNA family that modulates fibrosis and its applications
CA2694928A1 (en) * 2007-07-31 2009-02-05 Board Of Regents, The University Of Texas System Micro-rnas that control myosin expression and myofiber identity
CN102083980A (zh) * 2008-02-21 2011-06-01 得克萨斯系统大学董事会 调节平滑肌增殖和分化的微小rna及其用途
WO2009117418A2 (en) 2008-03-17 2009-09-24 The Board Of Regents Of The University Of Texas System Identification of micro-rnas involved in neuromuscular synapse maintenance and regeneration
US9738680B2 (en) 2008-05-21 2017-08-22 Rheinische Friedrich-Wilhelms-Universität Bonn 5′ triphosphate oligonucleotide with blunt end and uses thereof
US8193161B2 (en) 2008-06-09 2012-06-05 New York Medical College Compositions comprising cardiac stem cells overexpressing specific micrornas and methods of their use in repairing damaged myocardium
GB0811715D0 (en) * 2008-06-26 2008-07-30 Angeletti P Ist Richerche Bio Therapeutic agents
US8629119B2 (en) 2009-02-04 2014-01-14 The Board Of Regents, The University Of Texas System Dual targeting of MIR-208 and MIR-499 in the treatment of cardiac disorders
DK2427472T3 (en) 2009-05-05 2016-09-12 Miragen Therapeutics Lipophilic polynukleotidkonjugater
EP2435570A1 (en) * 2009-05-25 2012-04-04 Carola Ponzetto Differentiation therapy for sarcomas
JP5748736B2 (ja) * 2010-02-26 2015-07-15 Ｌｓｉｐファンド運営合同会社 筋原性疾患検出用マーカー及びそれを用いた検出方法
JP5928725B2 (ja) * 2010-04-08 2016-06-01 京都府公立大学法人 体液由来検体を用いた横紋筋肉腫の検出方法
EP2591095B1 (en) 2010-07-08 2016-04-27 Duke University Direct reprogramming of cells to cardiac myocyte fate
US20130302293A1 (en) * 2010-11-11 2013-11-14 Keith A. Webster Compositions, cells, kits and methods for autologous stem cell therapy
EP2652151A2 (en) 2010-12-15 2013-10-23 Miragen Therapeutics Microrna inhibitors comprising locked nucleotides
EP2508530A1 (en) 2011-03-28 2012-10-10 Rheinische Friedrich-Wilhelms-Universität Bonn Purification of triphosphorylated oligonucleotides using capture tags
WO2012153135A1 (en) * 2011-05-09 2012-11-15 University Of Glasgow Methods of modulating micrornas in the treatment of pulmonary arterial hypertension
WO2013006558A2 (en) * 2011-07-01 2013-01-10 Board Of Regents, The University Of Texas System Compositions and methods for treating skeletal myopathy
US20140259192A1 (en) * 2011-07-12 2014-09-11 Sanofi Transgenic animal comprising a deletion or functional deletion of the 3'utr of an endogenous gene
EP2755663A4 (en) 2011-09-13 2015-10-07 Ottawa Hospital Res Inst MicroRNA Inhibitors
EP2763703B1 (en) * 2011-10-06 2018-02-14 Miragen Therapeutics, Inc. Control of whole body energy homeostasis by microrna regulation
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CN103710387B (zh) * 2013-12-25 2015-10-14 天津农学院 一种促进牛骨骼肌卫星细胞体外增殖的方法
JP6566536B2 (ja) * 2014-06-16 2019-08-28 国立大学法人山口大学 フォワードプライマー
CN104498497A (zh) * 2014-12-10 2015-04-08 山东农业大学 一种与奶山羊乳腺上皮细胞凋亡相关的miRNA及其在奶山羊育种中的应用
JP6883791B2 (ja) 2015-01-14 2021-06-09 国立大学法人京都大学 骨格筋前駆細胞の選択方法
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US11365412B2 (en) 2017-04-05 2022-06-21 University Of Cincinnati Promotion of cardiomyocyte proliferation and regenerative treatment of the heart by inhibition of microRNA-128
WO2019035690A1 (ko) * 2017-08-18 2019-02-21 서울대학교병원 근육 질환 및 신경근육 질환 예방, 치료 또는 진단을 위한 miR-18b의 용도
CN111918968B (zh) * 2018-03-14 2023-11-24 贝斯以色列女执事医疗中心 Micro-RNA 22的抑制剂
CN108690846A (zh) * 2018-04-17 2018-10-23 上海大学 抑制MiR-29b基因表达的应用
CN108823209B (zh) * 2018-07-18 2021-04-09 华中农业大学 骨骼肌特异性启动子及应用
KR20210102870A (ko) 2018-08-30 2021-08-20 테나야 테라퓨틱스, 인코포레이티드 미오카르딘 및 ascl1을 사용한 심장 세포 재프로그래밍
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