|
US20030190740A1
(en)
|
1998-10-13 |
2003-10-09 |
The University Of Georgia Research Foundation, Inc |
Stabilized bioactive peptides and methods of identification, synthesis, and use
|
|
DE69926009D1
(de)
|
1998-10-13 |
2005-08-04 |
Univ Georgia Res Found |
Stabilisierte bioaktive peptide und methoden zu ihrer identifikation, synthese und verwendung
|
|
JP2003518075A
(ja)
|
1999-12-24 |
2003-06-03 |
ジェネンテック・インコーポレーテッド |
生理活性化合物の消失半減期延長のための方法及び組成物
|
|
US20050287153A1
(en)
*
|
2002-06-28 |
2005-12-29 |
Genentech, Inc. |
Serum albumin binding peptides for tumor targeting
|
|
US20040001827A1
(en)
*
|
2002-06-28 |
2004-01-01 |
Dennis Mark S. |
Serum albumin binding peptides for tumor targeting
|
|
DE10012120A1
(de)
*
|
2000-03-13 |
2001-09-27 |
Ktb Tumorforschungs Gmbh |
Therapeutische und diagnostische Ligandensysteme mit Transportmolekülbindenden Eigenschaften und diese enthaltende Arzneimittel
|
|
ATE368688T1
(de)
|
2000-11-08 |
2007-08-15 |
Fresenius Medical Care Affina |
Peptide, deren herstellung und verwendung zur bindung von immunglobulinen
|
|
EP1377306A1
(en)
|
2001-03-09 |
2004-01-07 |
Dyax Corp. |
Serum albumin binding moieties
|
|
US20030157561A1
(en)
*
|
2001-11-19 |
2003-08-21 |
Kolkman Joost A. |
Combinatorial libraries of monomer domains
|
|
US20050271663A1
(en)
*
|
2001-06-28 |
2005-12-08 |
Domantis Limited |
Compositions and methods for treating inflammatory disorders
|
|
US20110045005A1
(en)
|
2001-10-19 |
2011-02-24 |
Craig Crowley |
Compositions and methods for the treatment of tumor of hematopoietic origin
|
|
JP2005289809A
(ja)
*
|
2001-10-24 |
2005-10-20 |
Vlaams Interuniversitair Inst Voor Biotechnologie Vzw (Vib Vzw) |
突然変異重鎖抗体
|
|
US6916904B2
(en)
*
|
2002-04-24 |
2005-07-12 |
Zolaris Biosciences, Llc |
Inhibition of immune complex formation
|
|
US20090068178A1
(en)
*
|
2002-05-08 |
2009-03-12 |
Genentech, Inc. |
Compositions and Methods for the Treatment of Tumor of Hematopoietic Origin
|
|
CA2489596A1
(en)
*
|
2002-06-14 |
2003-12-24 |
Dyax Corporation |
Protein analysis
|
|
EP1600459A3
(en)
*
|
2002-06-28 |
2005-12-07 |
Domantis Limited |
Ligand
|
|
US9321832B2
(en)
|
2002-06-28 |
2016-04-26 |
Domantis Limited |
Ligand
|
|
US9320792B2
(en)
|
2002-11-08 |
2016-04-26 |
Ablynx N.V. |
Pulmonary administration of immunoglobulin single variable domains and constructs thereof
|
|
JP2006519763A
(ja)
|
2002-11-08 |
2006-08-31 |
アブリンクス エン.ヴェー. |
治療用ポリペプチドの投与法およびそのためのポリペプチド
|
|
US20060034845A1
(en)
|
2002-11-08 |
2006-02-16 |
Karen Silence |
Single domain antibodies directed against tumor necrosis factor alpha and uses therefor
|
|
US7329725B1
(en)
*
|
2003-10-29 |
2008-02-12 |
Nastech Pharmaceutical Company Inc. |
Phage displayed Trp cage ligands
|
|
ATE554107T1
(de)
|
2003-12-19 |
2012-05-15 |
Genentech Inc |
Als therapeutika geeignete monovalente antikörperfragmente
|
|
US8754031B2
(en)
|
2004-03-08 |
2014-06-17 |
Oncolix, Inc. |
Use of prolactin receptor antagonists in combination with an agent that inactivates the HER2/neu signaling pathway
|
|
AU2011253771B2
(en)
*
|
2004-03-10 |
2013-10-31 |
Trinity Therapeutics, Inc. |
Method for inhibiting immune complex formation in a subject
|
|
AU2005221187B2
(en)
*
|
2004-03-10 |
2011-09-01 |
Trinity Therapeutics, Inc. |
Method for inhibiting immune complex formation in a subjetc
|
|
EP2380594B1
(en)
|
2004-04-06 |
2019-12-04 |
Affibody AB |
Use of a serum albumin binding peptide to reduce the immunogenicity of a protein
|
|
CN114053429A
(zh)
|
2004-06-01 |
2022-02-18 |
健泰科生物技术公司 |
抗体-药物偶联物和方法
|
|
US8921528B2
(en)
|
2004-06-01 |
2014-12-30 |
Domantis Limited |
Bispecific fusion antibodies with enhanced serum half-life
|
|
WO2006015371A2
(en)
|
2004-08-05 |
2006-02-09 |
Genentech, Inc. |
Humanized anti-cmet antagonists
|
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
|
BRPI0516284A
(pt)
|
2004-09-23 |
2008-09-02 |
Genentech Inc |
anticorpo construìdo com cisteìna, método de selecionar anticorpos, compostos conjugados de droga-anticorpo, composição farmacêutica, método para matar ou inibir a proliferação de células de tumor, métodos de inibir a proliferação celular e o crescimento de células de tumor, artigo manufaturado e método para produzir um composto
|
|
GB0426146D0
(en)
|
2004-11-29 |
2004-12-29 |
Bioxell Spa |
Therapeutic peptides and method
|
|
JP4993645B2
(ja)
|
2004-12-01 |
2012-08-08 |
ジェネンテック, インコーポレイテッド |
抗体薬剤結合体および方法
|
|
BRPI0518761A2
(pt)
*
|
2004-12-02 |
2008-12-09 |
Domantis Ltd |
fusço de droga, conjugado de droga, Ácido nucleico recombinante, construÇço de Ácido nucleico, cÉlula hospedeira, mÉtodo para produzir uma fusço de droga, composiÇço farmacÊutica, droga, mÉtodo de tratamento e/ou prevenÇço de uma condiÇço em um paciente, mÉtodo de retardo ou prevenÇço de progressço de doenÇa, e, mÉtodo para diminuir a absorÇço de alimentos por um paciente
|
|
WO2006059110A2
(en)
*
|
2004-12-02 |
2006-06-08 |
Domantis Limited |
Plad domain peptides with increased serum half life due to conjugation to domain antibodies
|
|
EP1863847A2
(en)
*
|
2004-12-02 |
2007-12-12 |
Domantis Limited |
Anti-il-1r1 single domain antibodies and therapeutic uses
|
|
MX363423B
(es)
|
2005-05-18 |
2019-03-22 |
Ablynx Nv |
Nanobodiestm (nanocuerpos) mejorados contra el factor alfa de necrosis del tumor.
|
|
DE102005023617A1
(de)
|
2005-05-21 |
2006-11-23 |
Aspre Ag |
Verfahren zum Mischen von Farben in einem Display
|
|
WO2007094842A2
(en)
|
2005-12-02 |
2007-08-23 |
Genentech, Inc. |
Binding polypeptides and uses thereof
|
|
US20080200392A1
(en)
*
|
2005-09-06 |
2008-08-21 |
Bodie Neil M |
Methods for Treating Parkinson's Disease
|
|
US20100015146A1
(en)
*
|
2005-10-14 |
2010-01-21 |
Novo Nordisk A/S |
Treating diabetes using inhibitors of il-1
|
|
US7704953B2
(en)
*
|
2006-02-17 |
2010-04-27 |
Mdrna, Inc. |
Phage displayed cell binding peptides
|
|
US8486890B2
(en)
|
2006-03-15 |
2013-07-16 |
Novo Nordisk A/S |
Amylin derivatives
|
|
PT2032606E
(pt)
|
2006-05-30 |
2014-02-05 |
Genentech Inc |
Anticorpos e imunoconjugados e respetivas utilizações
|
|
CN101528767A
(zh)
*
|
2006-10-11 |
2009-09-09 |
埃博灵克斯股份有限公司 |
以基本不依赖pH的方式结合血清蛋白的氨基酸序列、包括其的化合物、及其用途
|
|
EP2845866B1
(en)
|
2006-10-27 |
2017-05-03 |
Genentech, Inc. |
Antibodies and immunoconjugates and uses therefor
|
|
WO2008071685A1
(en)
*
|
2006-12-13 |
2008-06-19 |
Ablynx N.V. |
Polypeptides specific for complexes involved in receptor-mediated signaling, such as the il-6/il-6 receptor complex
|
|
CA2671734A1
(en)
|
2006-12-19 |
2008-06-26 |
Genentech, Inc. |
Vegf-specific antagonists for adjuvant and neoadjuvant therapy and the treatment of early stage tumors
|
|
WO2009138519A1
(en)
|
2008-05-16 |
2009-11-19 |
Ablynx Nv |
AMINO ACID SEQUENCES DIRECTED AGAINST CXCR4 AND OTHER GPCRs AND COMPOUNDS COMPRISING THE SAME
|
|
US9512236B2
(en)
|
2006-12-19 |
2016-12-06 |
Ablynx N.V. |
Amino acid sequences directed against GPCRS and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders
|
|
EP2557090A3
(en)
|
2006-12-19 |
2013-05-29 |
Ablynx N.V. |
Amino acid sequences directed against GPCRs and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders
|
|
EP2102244A2
(en)
|
2006-12-19 |
2009-09-23 |
Ablynx N.V. |
Amino acid sequences directed against a metalloproteinase from the adam family and polypeptides comprising the same for the treatment of adam-related diseases and disorders
|
|
CA2676766A1
(en)
|
2007-02-09 |
2008-08-21 |
Genentech, Inc. |
Anti-robo4 antibodies and uses therefor
|
|
PL2176296T3
(pl)
|
2007-07-16 |
2012-07-31 |
Genentech Inc |
Przeciwciała anty-CD79B i immunokoniugaty i sposoby stosowania
|
|
PE20140625A1
(es)
|
2007-07-16 |
2014-05-29 |
Genentech Inc |
ANTICUERPOS ANTI-CD79b E INMUNOCONJUGADOS HUMANIZADOS
|
|
AU2008281913B2
(en)
|
2007-07-31 |
2013-11-07 |
Affibody Ab |
New albumin binding compositions, methods and uses
|
|
EP2036923A1
(en)
*
|
2007-09-11 |
2009-03-18 |
Novo Nordisk A/S |
Improved derivates of amylin
|
|
ES2622460T3
(es)
|
2007-09-26 |
2017-07-06 |
Ucb Biopharma Sprl |
Fusiones de anticuerpos con doble especificidad
|
|
KR100920729B1
(ko)
*
|
2007-10-01 |
2009-10-07 |
한국생명공학연구원 |
펩타이드 혼성체를 사용한 배향성이 조절된 항체단분자막의 제조방법
|
|
WO2009068627A2
(en)
|
2007-11-27 |
2009-06-04 |
Ablynx N.V. |
Amino acid sequences directed against heterodimeric cytokines and/or their receptors and polypeptides comprising the same
|
|
PT2247620T
(pt)
|
2008-01-31 |
2016-08-23 |
Genentech Inc |
Anticorpos e imunoconjugados anti-cd79b e métodos de utilização
|
|
CN102056945A
(zh)
|
2008-04-07 |
2011-05-11 |
埃博灵克斯股份有限公司 |
针对Notch途径的单可变结构域
|
|
CN102112155B
(zh)
|
2008-06-05 |
2016-08-10 |
埃博灵克斯股份有限公司 |
针对病毒包膜蛋白的氨基酸序列和用于治疗病毒疾病的包含其的多肽
|
|
EP3130603A1
(en)
|
2008-06-30 |
2017-02-15 |
ESBATech, an Alcon Biomedical Research Unit LLC |
Functionalized polypeptides
|
|
MX2011000009A
(es)
|
2008-07-10 |
2011-08-15 |
Esbatech Alcon Biomed Res Unit |
Metodos y composiciones para la administracion mejorada de macromoleculas.
|
|
US8815813B2
(en)
*
|
2008-07-18 |
2014-08-26 |
Trinity Therapeutics, Inc. |
Methods for treating immune-mediated Dengue Fever infections and antibody-dependent enhancement of Dengue Fever infections, including Dengue Hemorrhagic Fever and Dengue Shock Syndrome
|
|
SI2334705T1
(sl)
|
2008-09-26 |
2017-05-31 |
Ucb Biopharma Sprl |
Biološki produkti
|
|
WO2010046357A1
(en)
|
2008-10-21 |
2010-04-29 |
Novo Nordisk A/S |
Amylin derivatives
|
|
KR20110079693A
(ko)
|
2008-10-29 |
2011-07-07 |
와이어쓰 엘엘씨 |
단일 도메인 항원 결합 분자의 정제 방법
|
|
MX345226B
(es)
|
2008-10-29 |
2017-01-20 |
Ablynx Nv |
Formulaciones de moleculas de union a antigeno de dominio sencillo.
|
|
WO2010054699A1
(en)
*
|
2008-11-17 |
2010-05-20 |
Affibody Ab |
Conjugates of albumin binding domain
|
|
TWI612971B
(zh)
|
2008-11-22 |
2018-02-01 |
建南德克公司 |
用於乳癌治療之抗-血管新生療法
|
|
EP2370465B1
(en)
|
2008-12-19 |
2019-01-23 |
Ablynx N.V. |
Genetic immunization for producing immunoglobulins against cell-associated antigens such as p2x7, cxcr7 or cxcr4
|
|
CA2753804C
(en)
|
2009-02-26 |
2018-03-13 |
Oncolix, Inc. |
Compositions and methods for visualizing and eliminating cancer stem cells
|
|
US8648046B2
(en)
|
2009-02-26 |
2014-02-11 |
Oncolix, Inc. |
Compositions and methods for visualizing and eliminating cancer stem cells
|
|
US8410250B2
(en)
|
2009-03-25 |
2013-04-02 |
Genentech, Inc. |
Anti-FGFR3 antibodies and methods using same
|
|
CN102471380B
(zh)
|
2009-04-01 |
2015-01-14 |
霍夫曼-拉罗奇有限公司 |
抗FcRH5抗体和免疫偶联物及使用方法
|
|
SG174862A1
(en)
|
2009-04-10 |
2011-11-28 |
Ablynx Nv |
Improved amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of il-6r related diseases and disorder
|
|
SMT201700376T1
(it)
|
2009-06-05 |
2017-09-07 |
Ablynx Nv |
Costrutti trivalenti di nanobody anti-virus respiratorio sinciziale umano (hrsv) per la prevenzione e/o il trattamento di infezioni del tratto respiratorio
|
|
TW201431558A
(zh)
|
2009-08-15 |
2014-08-16 |
建南德克公司 |
用於治療先前治療過之乳癌之抗-血管新生療法
|
|
EP2475391B1
(en)
|
2009-09-09 |
2018-09-12 |
Centrose, LLC |
Extracellular targeted drug conjugates
|
|
GB201005063D0
(en)
|
2010-03-25 |
2010-05-12 |
Ucb Pharma Sa |
Biological products
|
|
AU2010310585A1
(en)
|
2009-10-22 |
2012-05-03 |
Genentech, Inc. |
Anti-hepsin antibodies and methods using same
|
|
WO2011057120A1
(en)
|
2009-11-05 |
2011-05-12 |
Genentech, Inc. |
Methods and composition for secretion of heterologous polypeptides
|
|
NZ600278A
(en)
|
2009-11-13 |
2014-04-30 |
Grifols Therapeutics Inc |
Von willebrand factor (vwf)-containing preparations, and methods, kits, and uses related thereto
|
|
EP2507262A1
(en)
|
2009-11-30 |
2012-10-10 |
Ablynx N.V. |
Improved amino acid sequences directed against human respiratory syncytial virus (hrsv) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections
|
|
BR112012012983A2
(pt)
|
2009-12-04 |
2020-09-15 |
Genentech Inc |
método para sintetizar um anticorpo multiespecífico, método para sintetizar um painel de anticorpos multiespecíficos, método para sintetizar um análogo de anticorpo, método para sintetizar um painel de análogos de anticorpo e composições
|
|
EP2509997B1
(en)
|
2009-12-07 |
2017-08-30 |
i2 Pharmaceuticals, Inc. |
Conjugates comprising an antibody surrogate scaffold with improved pharmacokinetic properties
|
|
EP3309176B1
(en)
|
2009-12-14 |
2025-10-01 |
Ablynx N.V. |
Immunoglobulin single variable domain antibodies against ox40l, constructs and their therapeutic use
|
|
WO2011083141A2
(en)
|
2010-01-08 |
2011-07-14 |
Ablynx Nv |
Method for generation of immunoglobulin sequences by using lipoprotein particles
|
|
US9120855B2
(en)
|
2010-02-10 |
2015-09-01 |
Novartis Ag |
Biologic compounds directed against death receptor 5
|
|
CN103237810A
(zh)
|
2010-02-23 |
2013-08-07 |
霍夫曼-拉罗奇有限公司 |
用于治疗卵巢癌的抗血管发生疗法
|
|
WO2011117423A1
(en)
|
2010-03-26 |
2011-09-29 |
Ablynx N.V. |
Immunoglobulin single variable domains directed against cxcr7
|
|
NZ602241A
(en)
|
2010-04-15 |
2015-03-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
SG185354A1
(en)
|
2010-05-20 |
2012-12-28 |
Ablynx Nv |
Biological materials related to her3
|
|
WO2011153243A2
(en)
|
2010-06-02 |
2011-12-08 |
Genentech, Inc. |
Anti-angiogenesis therapy for treating gastric cancer
|
|
SG185430A1
(en)
|
2010-06-03 |
2012-12-28 |
Genentech Inc |
Immuno-pet imaging of antibodies and immunoconjugates and uses therefor
|
|
SG185428A1
(en)
|
2010-06-08 |
2012-12-28 |
Genentech Inc |
Cysteine engineered antibodies and conjugates
|
|
EP2933262B1
(en)
|
2010-07-09 |
2018-05-02 |
Affibody AB |
Polypeptides
|
|
BR112013007442A2
(pt)
|
2010-09-28 |
2019-09-24 |
Amylin Pharmaceuticals Llc |
polipeptídeos construídos tendo duração de ação realçada
|
|
WO2012042026A1
(en)
|
2010-09-30 |
2012-04-05 |
Ablynx Nv |
Biological materials related to c-met
|
|
CU24111B1
(es)
|
2010-11-08 |
2015-08-27 |
Novartis Ag |
Polipéptidos que se enlazan a cxcr2
|
|
JP5889912B2
(ja)
|
2010-11-17 |
2016-03-22 |
ジェネンテック, インコーポレイテッド |
アラニニルメイタンシノール抗体コンジュゲート
|
|
AU2011333666B2
(en)
|
2010-11-26 |
2017-02-02 |
Molecular Partners Ag |
Improved capping modules for designed ankyrin repeat proteins
|
|
CA2827170A1
(en)
|
2011-02-11 |
2012-08-16 |
David M. Hilbert |
Monovalent and multivalent multispecific complexes and uses thereof
|
|
JP6181040B2
(ja)
|
2011-03-28 |
2017-08-16 |
アブリンクス エン.ヴェー. |
二特異性抗cxcr7免疫グロブリン単一可変ドメイン
|
|
UA117218C2
(uk)
|
2011-05-05 |
2018-07-10 |
Мерк Патент Гмбх |
Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
|
|
WO2012155019A1
(en)
|
2011-05-12 |
2012-11-15 |
Genentech, Inc. |
Multiple reaction monitoring lc-ms/ms method to detect therapeutic antibodies in animal samples using framework signature pepides
|
|
US9505840B2
(en)
|
2011-05-27 |
2016-11-29 |
Ablynx N.V. |
Inhibition of bone resorption with RANKL binding peptides
|
|
AU2012273928A1
(en)
|
2011-06-23 |
2014-02-06 |
Ablynx Nv |
Immunoglobulin single variable domains directed against IgE
|
|
TW201306866A
(zh)
|
2011-06-30 |
2013-02-16 |
Genentech Inc |
抗-c-met抗體調配物
|
|
CA2840552A1
(en)
|
2011-07-01 |
2013-01-10 |
Bayer Intellectual Property Gmbh |
Relaxin fusion polypeptides and uses thereof
|
|
CN103649116A
(zh)
|
2011-07-08 |
2014-03-19 |
拜耳知识产权有限责任公司 |
释放松弛素的融合蛋白及其用途
|
|
US20130022551A1
(en)
|
2011-07-22 |
2013-01-24 |
Trustees Of Boston University |
DEspR ANTAGONISTS AND AGONISTS AS THERAPEUTICS
|
|
US9365619B2
(en)
|
2011-08-24 |
2016-06-14 |
Otsuka Chemical Co., Ltd. |
IgG-binding peptide and method for detecting and purifying IgG using same
|
|
US20150044208A1
(en)
|
2011-09-23 |
2015-02-12 |
Technophage, Investigaçäo E Desenvolvimento Em Biotecnologia, Sa |
Modified Albumin-Binding Domains and Uses Thereof to Improve Pharmacokinetics
|
|
EP2758434A2
(en)
|
2011-09-23 |
2014-07-30 |
Technophage, Investigação E Desenvolvimento Em Biotecnologia, SA |
Anti-tumor necrosis factor-alpha agents and uses thereof
|
|
WO2013041722A1
(en)
|
2011-09-23 |
2013-03-28 |
Ablynx Nv |
Prolonged inhibition of interleukin-6 mediated signaling
|
|
CN103889451B
(zh)
|
2011-09-30 |
2016-06-29 |
埃博灵克斯股份有限公司 |
与C-Met相关的生物物质
|
|
PL2750713T3
(pl)
|
2011-10-14 |
2016-03-31 |
Medimmune Ltd |
Pirolobenzodiazepiny i ich koniugaty
|
|
MX351502B
(es)
|
2011-11-11 |
2017-10-18 |
Ucb Pharma Sa |
Anticuerpos de union de albumina y fragmentos de union de los mismos.
|
|
WO2013128027A1
(en)
*
|
2012-03-01 |
2013-09-06 |
Amgen Research (Munich) Gmbh |
Long life polypeptide binding molecules
|
|
WO2013130093A1
(en)
|
2012-03-02 |
2013-09-06 |
Genentech, Inc. |
Biomarkers for treatment with anti-tubulin chemotherapeutic compounds
|
|
JP2020033372A
(ja)
*
|
2012-03-28 |
2020-03-05 |
アフィボディ・アーベー |
経口投与
|
|
WO2013143890A1
(en)
|
2012-03-28 |
2013-10-03 |
Affibody Ab |
Oral administration
|
|
US9328174B2
(en)
|
2012-05-09 |
2016-05-03 |
Novartis Ag |
Chemokine receptor binding polypeptides
|
|
KR20220051197A
(ko)
|
2012-05-17 |
2022-04-26 |
익스텐드 바이오사이언시즈, 인크. |
개선된 약물 전달용 캐리어
|
|
US8822423B2
(en)
*
|
2012-05-17 |
2014-09-02 |
Janssen Biotech, Inc. |
Affinity peptides toward infliximab
|
|
WO2013177481A1
(en)
|
2012-05-25 |
2013-11-28 |
Immunogen, Inc. |
Benzodiazepines and conjugates thereof
|
|
MX355041B
(es)
|
2012-05-25 |
2018-03-28 |
Janssen Biotech Inc |
Dominios de union a albumina consenso no naturales.
|
|
US9856314B2
(en)
*
|
2012-06-22 |
2018-01-02 |
Cytomx Therapeutics, Inc. |
Activatable antibodies having non-binding steric moieties and methods of using the same
|
|
JP6152379B2
(ja)
*
|
2012-06-29 |
2017-06-21 |
旭化成メディカル株式会社 |
プロテインaのbドメイン変異体を含むポリペプチドが結合された担体からなる吸着材
|
|
WO2014048977A1
(en)
|
2012-09-25 |
2014-04-03 |
Affibody Ab |
Albumin binding polzpeptide
|
|
CA2885340C
(en)
|
2012-10-12 |
2016-11-08 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
US9931415B2
(en)
|
2012-10-12 |
2018-04-03 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
PT3470086T
(pt)
|
2012-10-12 |
2021-02-01 |
Medimmune Ltd |
Pirrolobenzodiazepinas e conjugados das mesmas
|
|
HRP20181646T2
(hr)
|
2012-10-12 |
2019-08-09 |
Adc Therapeutics Sa |
Konjugati pirolobenzodiazepin - anti-psma protutijela
|
|
SMT201900017T1
(it)
|
2012-10-12 |
2019-02-28 |
Medimmune Ltd |
Coniugati pirrolobenzodiazepina-anticorpo
|
|
US10736903B2
(en)
|
2012-10-12 |
2020-08-11 |
Medimmune Limited |
Pyrrolobenzodiazepine-anti-PSMA antibody conjugates
|
|
HRP20171916T1
(hr)
|
2012-10-12 |
2018-02-09 |
Adc Therapeutics Sa |
Konjugati protutijelo anti-cd22 - pirolobenzodiazepin
|
|
WO2014057120A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
|
EP2912051B1
(en)
|
2012-10-25 |
2018-04-18 |
Affibody AB |
Method for the separation of proteins containing an albumin-binding domain
|
|
JP6382826B2
(ja)
|
2012-10-25 |
2018-08-29 |
アフィボディ・アーベー |
アルブミン結合ポリペプチド
|
|
BR112015014669B1
(pt)
|
2012-12-21 |
2023-09-26 |
Medimmune Limited |
Compostos pirrolobenzodiazepinas, conjugados compreendendo os mesmos e uso destes para tratar uma doença proliferativa
|
|
AU2013366490B9
(en)
|
2012-12-21 |
2018-02-01 |
Medimmune Limited |
Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases
|
|
EP2752426A1
(en)
|
2013-01-03 |
2014-07-09 |
Covagen AG |
Human serum albumin binding compounds and fusion proteins thereof
|
|
WO2014115229A1
(ja)
|
2013-01-28 |
2014-07-31 |
独立行政法人産業技術総合研究所 |
抗体結合性ペプチド
|
|
EA027910B1
(ru)
|
2013-03-13 |
2017-09-29 |
Медимьюн Лимитед |
Пирролобензодиазепины и их конъюгаты
|
|
CN105142674B
(zh)
|
2013-03-13 |
2018-11-13 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓和其结合物
|
|
NZ712035A
(en)
|
2013-03-13 |
2019-06-28 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
US20160152686A1
(en)
|
2013-03-13 |
2016-06-02 |
Bristol-Myers Squibb Company |
Fibronectin based scaffold domains linked to serum albumin or moiety binding thereto
|
|
TW201525001A
(zh)
|
2013-03-15 |
2015-07-01 |
Amgen Res Munich Gmbh |
包含n-端abp之單鏈結合分子
|
|
CA2918139A1
(en)
|
2013-08-12 |
2015-02-19 |
Genentech, Inc. |
1-(chloromethyl)-2,3-dihydro-1h-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment
|
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EP3054986B1
(en)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
EP3054985B1
(en)
|
2013-10-11 |
2018-12-26 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
EP3054983B1
(en)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
EP3082876B1
(en)
|
2013-12-16 |
2018-01-17 |
Genentech, Inc. |
1-(chloromethyl)-2,3-dihydro-1h-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment
|
|
BR112016012410A2
(pt)
|
2013-12-16 |
2017-09-26 |
Genentech Inc |
conjugado de droga e anticorpo, composto conjugado de droga e anticorpo, composto não-peptídico, método de tratamento de doenças em seres humanos e composição farmacêutica
|
|
UA118113C2
(uk)
|
2013-12-16 |
2018-11-26 |
Дженентек, Інк. |
Пептидоміметичні сполуки та їх кон'югати антитіла з лікарським засобом
|
|
WO2015091957A1
(en)
|
2013-12-20 |
2015-06-25 |
Affibody Ab |
Engineered albumin binding polypeptide
|
|
WO2015132248A2
(en)
*
|
2014-03-03 |
2015-09-11 |
Vrije Universiteit Brussel (Vub) |
Sequamers - a novel non-natural type of peptide libraries randomly constrained by their primary sequences
|
|
HRP20211748T1
(hr)
|
2014-03-14 |
2022-02-18 |
F. Hoffmann - La Roche Ag |
Postupci i sastavi za sekreciju heterolognih polipeptida
|
|
WO2015148531A1
(en)
|
2014-03-24 |
2015-10-01 |
Genentech, Inc. |
Cancer treatment with c-met antagonists and correlation of the latter with hgf expression
|
|
EP2940128A1
(en)
*
|
2014-04-30 |
2015-11-04 |
Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) |
Adenovirus comprising an albumin-binding moiety
|
|
CN113501880A
(zh)
|
2014-05-02 |
2021-10-15 |
动量制药公司 |
涉及工程化Fc构建体的组合物和方法
|
|
NL2013661B1
(en)
|
2014-10-21 |
2016-10-05 |
Ablynx Nv |
KV1.3 Binding immunoglobulins.
|
|
US10188746B2
(en)
|
2014-09-10 |
2019-01-29 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
JP6622293B2
(ja)
|
2014-09-12 |
2019-12-18 |
ジェネンテック, インコーポレイテッド |
アントラサイクリンジスルフィド中間体、抗体−薬物複合体、及び方法
|
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
MX2017003123A
(es)
|
2014-09-12 |
2017-05-12 |
Genentech Inc |
Anticuerpos y conjugados modificados geneticamente con cisteina.
|
|
CR20170099A
(es)
|
2014-09-17 |
2017-07-19 |
Genentech Inc |
Pirrolobenzodiazepinas y conjugados de anticuerpos-disulfuro de las mismas
|
|
DK3262071T3
(da)
|
2014-09-23 |
2020-06-15 |
Hoffmann La Roche |
Fremgangsmåde til anvendelse af anti-CD79b-immunkonjugater
|
|
US9789197B2
(en)
|
2014-10-22 |
2017-10-17 |
Extend Biosciences, Inc. |
RNAi vitamin D conjugates
|
|
WO2016065052A1
(en)
|
2014-10-22 |
2016-04-28 |
Extend Biosciences, Inc. |
Insulin vitamin d conjugates
|
|
CA2964463C
(en)
|
2014-10-22 |
2024-02-13 |
Extend Biosciences, Inc. |
Therapeutic vitamin d conjugates
|
|
KR20170080675A
(ko)
|
2014-11-05 |
2017-07-10 |
제넨테크, 인크. |
항-fgfr2/3 항체 및 이의 이용 방법
|
|
CA2968447A1
(en)
|
2014-11-25 |
2016-06-02 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates and their use to treat neoplasms
|
|
AU2015358532C1
(en)
|
2014-12-03 |
2020-10-29 |
Genentech, Inc. |
Quaternary amine compounds and antibody-drug conjugates thereof
|
|
USRE49529E1
(en)
|
2014-12-19 |
2023-05-16 |
Inozyme Pharma, Inc. |
Methods of treating tissue calcification
|
|
EP3277316B1
(en)
|
2015-04-02 |
2025-03-05 |
Ablynx N.V. |
Bispecific cxcr4-cd-4 polypeptides with potent anti-hiv activity
|
|
JP6892433B2
(ja)
|
2015-04-03 |
2021-06-23 |
ユニバーシティ・オブ・マサチューセッツUniversity Of Massachusetts |
十分に安定化された非対称sirna
|
|
CA2981616C
(en)
|
2015-04-06 |
2025-06-17 |
Arcellx, Inc. |
De novo binding domain polypeptides and their uses
|
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
|
WO2016180969A1
(en)
|
2015-05-13 |
2016-11-17 |
Ablynx N.V. |
T cell recruiting polypeptides based on tcr alpha/beta reactivity
|
|
DK3294319T3
(da)
|
2015-05-13 |
2024-07-22 |
Ablynx Nv |
T-celle-rekrutterende polypeptider baseret på cd3-reaktivitet
|
|
WO2016193380A1
(en)
|
2015-06-02 |
2016-12-08 |
Novo Nordisk A/S |
Insulins with polar recombinant extensions
|
|
CA2995110A1
(en)
|
2015-08-14 |
2017-02-23 |
University Of Massachusetts |
Bioactive conjugates for oligonucleotide delivery
|
|
MA43348A
(fr)
|
2015-10-01 |
2018-08-08 |
Novo Nordisk As |
Conjugués de protéines
|
|
EP3366693B1
(en)
*
|
2015-10-23 |
2023-08-16 |
FUJIFILM Corporation |
Cyclic peptide, affinity chromatography support, labeled antibody, antibody-drug conjugate, and pharmaceutical preparation
|
|
JP7256011B2
(ja)
|
2015-11-27 |
2023-04-11 |
アブリンクス エン.ヴェー. |
Cd40lを阻害するポリペプチド
|
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
|
US10478503B2
(en)
|
2016-01-31 |
2019-11-19 |
University Of Massachusetts |
Branched oligonucleotides
|
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
JP7091248B2
(ja)
|
2016-03-01 |
2022-06-27 |
ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイ |
低減されたl-グルタミナーゼ活性および増強された安定性を有するl-アスパラギナーゼ変異体および融合タンパク質
|
|
WO2017151971A2
(en)
|
2016-03-02 |
2017-09-08 |
Momenta Pharmaceuticals, Inc. |
METHODS RELATED TO ENGINEERED Fc CONSTRUCTS
|
|
EP4273551A3
(en)
|
2016-03-25 |
2024-01-17 |
F. Hoffmann-La Roche AG |
Multiplexed total antibody and antibody-conjugated drug quantification assay
|
|
SG11201808914UA
(en)
|
2016-04-15 |
2018-11-29 |
Berkeley Lights Inc |
Methods, systems and kits for in-pen assays
|
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
AU2017272111B2
(en)
|
2016-05-23 |
2024-05-16 |
Momenta Pharmaceuticals, Inc. |
Compositions and methods related to engineered Fc constructs
|
|
EP3465221B1
(en)
|
2016-05-27 |
2020-07-22 |
H. Hoffnabb-La Roche Ag |
Bioanalytical method for the characterization of site-specific antibody-drug conjugates
|
|
AU2017273743B2
(en)
|
2016-06-03 |
2021-12-02 |
Janssen Biotech, Inc. |
Serum albumin-binding fibronectin type III domains
|
|
US11364284B2
(en)
|
2016-06-16 |
2022-06-21 |
Inozyme Pharma, Inc. |
Methods of treating myointimal proliferation
|
|
WO2018007442A1
(en)
|
2016-07-06 |
2018-01-11 |
Ablynx N.V. |
Treatment of il-6r related diseases
|
|
WO2018029182A1
(en)
|
2016-08-08 |
2018-02-15 |
Ablynx N.V. |
Il-6r single variable domain antibodies for treatment of il-6r related diseases
|
|
CA3033368A1
(en)
|
2016-08-12 |
2018-02-15 |
University Of Massachusetts |
Conjugated oligonucleotides
|
|
US11008365B2
(en)
|
2016-09-01 |
2021-05-18 |
National Institute Of Advanced Industrial Science And Technology |
Polypeptide exhibiting affinity to antibodies forming non-native three-dimensional structure
|
|
WO2018050833A1
(en)
|
2016-09-15 |
2018-03-22 |
Ablynx Nv |
Immunoglobulin single variable domains directed against macrophage migration inhibitory factor
|
|
EP3521300A4
(en)
*
|
2016-09-30 |
2019-12-25 |
FUJIFILM Corporation |
CYCLIC PEPTIDE, AFFINITY CHROMATOGRAPHY CARRIER, MARKED ANTIBODY, ANTIBODY-ACTIVE SUBSTANCE CONJUGATE AND PHARMACEUTICAL PREPARATION
|
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
US11912750B2
(en)
|
2016-11-10 |
2024-02-27 |
Keros Therapeutics, Inc. |
GDNF fusion polypeptides and methods of use thereof
|
|
KR20240076829A
(ko)
|
2016-11-16 |
2024-05-30 |
아블린쓰 엔.브이. |
Cd123 및 tcr 알파/베타에 결합할 수 있는 t 세포 동원 폴리펩티드
|
|
SG10202107391YA
(en)
|
2017-01-06 |
2021-08-30 |
Momenta Pharmaceuticals Inc |
Compositions and methods related to engineered fc constructs
|
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
|
MX375569B
(es)
|
2017-02-08 |
2025-03-04 |
Adc Therapeutics Sa |
Conjugados de pirrolobenzodiazepinas y anticuerpos
|
|
JP2020513019A
(ja)
|
2017-04-05 |
2020-04-30 |
ノヴォ ノルディスク アー/エス |
オリゴマー伸長インスリン−Fcコンジュゲート
|
|
SI3612537T1
(sl)
|
2017-04-18 |
2022-10-28 |
Medimmune Limited |
Konjugati pirolobenzodiazepina
|
|
JP7408396B2
(ja)
|
2017-04-20 |
2024-01-05 |
アーデーセー セラピューティクス ソシエテ アノニム |
併用療法
|
|
WO2018199337A1
(ja)
|
2017-04-28 |
2018-11-01 |
味の素株式会社 |
可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩
|
|
EP3630817A1
(en)
|
2017-06-02 |
2020-04-08 |
Merck Patent GmbH |
Polypeptides binding adamts5, mmp13 and aggrecan
|
|
US11603401B2
(en)
|
2017-06-02 |
2023-03-14 |
Ablynx N.V. |
Aggrecan binding immunoglobulins
|
|
TW202417517A
(zh)
|
2017-06-02 |
2024-05-01 |
德商麥克專利有限公司 |
與mmp13結合之免疫球蛋白
|
|
LT3630847T
(lt)
|
2017-06-02 |
2024-12-10 |
Merck Patent Gmbh |
Adamts surišantys imunoglobulinai
|
|
BR112019026564A2
(pt)
|
2017-06-14 |
2020-06-30 |
Adc Therapeutics Sa |
regimes de dosagem para a administração de um adc anti-cd19
|
|
EP3642341A4
(en)
|
2017-06-23 |
2021-06-16 |
University Of Massachusetts |
TWO-DAY SELF-RELEASING SIRNA AND RELATED PROCEDURES
|
|
JP7684803B2
(ja)
|
2017-07-11 |
2025-05-28 |
アレクシオン ファーマシューティカルズ, インコーポレイテッド |
補体成分c5または血清アルブミンと結合するポリペプチドおよびその融合タンパク質
|
|
US11077199B2
(en)
|
2017-08-09 |
2021-08-03 |
Massachusetts Institute Of Technology |
Albumin binding peptide conjugates and methods thereof
|
|
AU2018313253B2
(en)
|
2017-08-11 |
2024-09-26 |
The Board Of Trustees Of The University Of Illinois |
Truncated guinea pig L-asparaginase variants and methods of use
|
|
KR102312910B1
(ko)
|
2017-08-18 |
2021-10-15 |
메디뮨 리미티드 |
피롤로벤조디아제핀 컨쥬게이트
|
|
US12134790B2
(en)
|
2017-09-27 |
2024-11-05 |
Inozyme Pharma, Inc. |
Methods of improving cardiovascular function and treating cardiovascular disease using a recombinant ectonucleotide pyrophosphatase phosphodiesterase (NPP1)
|
|
PE20200849A1
(es)
|
2017-10-10 |
2020-08-20 |
Numab Therapeutics AG |
Anticuerpo multiespecifico
|
|
WO2019075476A2
(en)
|
2017-10-15 |
2019-04-18 |
Berkeley Lights, Inc. |
METHODS, SYSTEMS AND KITS FOR ENCLOSED TESTS
|
|
CA3082410A1
(en)
|
2017-11-14 |
2019-05-23 |
Arcellx, Inc. |
Multifunctional immune cell therapies
|
|
KR20250137191A
(ko)
|
2017-11-14 |
2025-09-17 |
아르셀엑스, 인크. |
D-도메인 함유 폴리펩타이드 및 이의 용도
|
|
KR102037336B1
(ko)
|
2017-11-29 |
2019-10-29 |
아주대학교산학협력단 |
항체와 생리활성물질의 접합방법
|
|
WO2019107962A2
(ko)
*
|
2017-11-29 |
2019-06-06 |
아주대학교 산학협력단 |
항체와 생리활성물질의 접합방법
|
|
GB201803342D0
(en)
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
CN120665147A
(zh)
|
2018-06-14 |
2025-09-19 |
味之素株式会社 |
具有针对抗体的亲和性物质和生物正交性官能团的化合物或其盐
|
|
WO2019246003A1
(en)
|
2018-06-18 |
2019-12-26 |
Anwita Biosciences, Inc. |
Anti-mesothelin constructs and uses thereof
|
|
KR20210093227A
(ko)
|
2018-08-10 |
2021-07-27 |
유니버시티 오브 매사추세츠 |
Snp를 표적화하는 변형된 올리고뉴클레오티드
|
|
JP7627042B2
(ja)
|
2018-08-23 |
2025-02-05 |
ユニバーシティー オブ マサチューセッツ |
O-メチルリッチ完全安定化オリゴヌクレオチド
|
|
EP3856764A4
(en)
|
2018-09-27 |
2022-11-02 |
Xilio Development, Inc. |
MASKED CYTOKINE POLYPEPTIDES
|
|
EP3882261A4
(en)
|
2018-10-31 |
2023-02-08 |
Ajinomoto Co., Inc. |
COMPOUND COMPRISING A SUBSTANCE HAVING AN AFFINITY FOR AN ANTIBODY, CLEAVAGE SITE AND CORRESPONDING REACTIVE GROUP OR SALT
|
|
JP2022513198A
(ja)
|
2018-12-10 |
2022-02-07 |
ジェネンテック, インコーポレイテッド |
Fc含有タンパク質への部位特異的コンジュゲーションのための光架橋性ペプチド
|
|
EP3898701A4
(en)
|
2018-12-20 |
2022-10-26 |
Kleo Pharmaceuticals, Inc. |
COMBINATION THERAPY OF WEAPONS AND NATURAL KILLER CELLS
|
|
JP2022523467A
(ja)
|
2019-01-18 |
2022-04-25 |
ユニバーシティ・オブ・マサチューセッツ |
動的な薬物動態を修飾するアンカー
|
|
SG11202108900WA
(en)
|
2019-03-15 |
2021-09-29 |
Medimmune Ltd |
Azetidobenzodiazepine dimers and conjugates comprising them for use in the treatment of cancer
|
|
CA3149835A1
(en)
|
2019-08-09 |
2021-02-18 |
University Of Massachusetts |
Chemically modified oligonucleotides targeting snps
|
|
US12365894B2
(en)
|
2019-09-16 |
2025-07-22 |
University Of Massachusetts |
Branched lipid conjugates of siRNA for specific tissue delivery
|
|
EP3816185A1
(en)
|
2019-11-04 |
2021-05-05 |
Numab Therapeutics AG |
Multispecific antibody directed against pd-l1 and a tumor-associated antigen
|
|
CA3161723A1
(en)
|
2019-12-18 |
2021-06-24 |
Karyn O'neil |
Serum albumin-binding fibronectin type iii domains and uses thereof
|
|
GB201919061D0
(en)
|
2019-12-20 |
2020-02-05 |
Ucb Biopharma Sprl |
Multi-specific antibody
|
|
CN115516318A
(zh)
|
2020-03-09 |
2022-12-23 |
伯克利之光生命科技公司 |
用于坞内测定的方法、系统和试剂盒
|
|
EP3915580A1
(en)
|
2020-05-29 |
2021-12-01 |
Numab Therapeutics AG |
Multispecific antibody
|
|
AU2021301788A1
(en)
|
2020-06-30 |
2023-01-19 |
Gaia Biomedicine Inc. |
Method for stabilizing binding of NK cell and antibody, and use thereof
|
|
EP3988568A1
(en)
|
2020-10-21 |
2022-04-27 |
Numab Therapeutics AG |
Combination treatment
|
|
WO2022098743A1
(en)
|
2020-11-03 |
2022-05-12 |
Indi Molecular, Inc. |
Compositions, imaging, and therapeutic methods targeting folate receptor 1 (folr1)
|
|
WO2022098745A1
(en)
|
2020-11-03 |
2022-05-12 |
Indi Molecular, Inc. |
Compositions, delivery systems, and methods useful in tumor therapy
|
|
PE20231953A1
(es)
|
2020-12-07 |
2023-12-06 |
UCB Biopharma SRL |
Anticuerpos multiespecificos y combinaciones de anticuerpos
|
|
US20240392003A1
(en)
|
2021-02-02 |
2024-11-28 |
Numab Therapeutics AG |
Multispecific antibodies having specificity for ror1 and cd3
|
|
AU2022224636A1
(en)
|
2021-02-19 |
2023-09-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Single domain antibodies that neutralize sars-cov-2
|
|
JP2024512590A
(ja)
|
2021-03-26 |
2024-03-19 |
アーセルクス インコーポレイテッド |
多機能免疫細胞療法
|
|
WO2022271786A1
(en)
|
2021-06-23 |
2022-12-29 |
University Of Massachusetts |
Optimized anti-flt1 oligonucleotide compounds for treatment of preeclampsia and other angiogenic disorders
|
|
EP4183800A1
(en)
|
2021-11-19 |
2023-05-24 |
Medizinische Hochschule Hannover |
Novel sars-cov-2 neutralizing antibodies
|
|
KR20230132640A
(ko)
|
2022-03-04 |
2023-09-15 |
앱티스 주식회사 |
티올 반응성 에디티브를 이용한 항체-약물 컨쥬게이트의 제조 수율을 높이는 방법
|
|
KR20250019100A
(ko)
|
2022-06-02 |
2025-02-07 |
아지노모토 가부시키가이샤 |
친화성 물질, 화합물, 항체 및 그것들의 염
|
|
PE20251082A1
(es)
|
2022-07-08 |
2025-04-10 |
Novo Nordisk As |
Compuestos de isvd altamente potentes capaces de sustituir al fviii(a)
|
|
WO2024038095A1
(en)
|
2022-08-16 |
2024-02-22 |
Iome Bio |
NOVEL ANTI-RGMb ANTIBODIES
|
|
KR20250075704A
(ko)
|
2022-09-30 |
2025-05-28 |
익스텐드 바이오사이언시즈, 인크. |
장기-지속형 부갑상선 호르몬
|
|
EP4605077A1
(en)
|
2022-10-18 |
2025-08-27 |
Confo Therapeutics N.V. |
Amino acid sequences directed against the melanocortin 4 receptor and polypeptides comprising the same for the treatment of mc4r-related diseases and disorders
|
|
AU2024277146A1
(en)
*
|
2023-05-22 |
2025-11-27 |
Kaida Biopharmaceuticals, Inc. |
Antagonist fusion polypeptides
|
|
US12473529B2
(en)
|
2023-07-18 |
2025-11-18 |
Nanotein Technologies, Inc. |
Reagents, reagent kits, and culture media for activating and expanding immune cells and uses thereof
|
|
US12377158B1
(en)
*
|
2024-07-05 |
2025-08-05 |
Michael Farber |
Enhanced peptide constructs for albumin binding
|