JP2007269812A5 - - Google Patents

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Publication number
JP2007269812A5
JP2007269812A5 JP2007154127A JP2007154127A JP2007269812A5 JP 2007269812 A5 JP2007269812 A5 JP 2007269812A5 JP 2007154127 A JP2007154127 A JP 2007154127A JP 2007154127 A JP2007154127 A JP 2007154127A JP 2007269812 A5 JP2007269812 A5 JP 2007269812A5
Authority
JP
Japan
Prior art keywords
endotoxemia
inhibitor
compound
pharmaceutically acceptable
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007154127A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007269812A (ja
JP4712001B2 (ja
Filing date
Publication date
Priority claimed from US08/461,675 external-priority patent/US5750664A/en
Application filed filed Critical
Publication of JP2007269812A publication Critical patent/JP2007269812A/ja
Publication of JP2007269812A5 publication Critical patent/JP2007269812A5/ja
Application granted granted Critical
Publication of JP4712001B2 publication Critical patent/JP4712001B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2007154127A 1995-06-05 2007-06-11 エンドトキセミアの治療及び防止に有用な置換されたリポ糖類 Expired - Lifetime JP4712001B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/461,675 US5750664A (en) 1995-06-05 1995-06-05 Substituted liposaccharides useful in the treatment and prevention of endotoxemia
US08/461,675 1995-06-05

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP50186897A Division JP4009318B2 (ja) 1995-06-05 1996-06-05 エンドトキセミアの治療及び防止に有用な置換されたリポ糖類

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011018401A Division JP2011121970A (ja) 1995-06-05 2011-01-31 エンドトキセミアの治療及び防止に有用な置換されたリポ糖類

Publications (3)

Publication Number Publication Date
JP2007269812A JP2007269812A (ja) 2007-10-18
JP2007269812A5 true JP2007269812A5 (enExample) 2008-01-24
JP4712001B2 JP4712001B2 (ja) 2011-06-29

Family

ID=23833509

Family Applications (3)

Application Number Title Priority Date Filing Date
JP50186897A Expired - Lifetime JP4009318B2 (ja) 1995-06-05 1996-06-05 エンドトキセミアの治療及び防止に有用な置換されたリポ糖類
JP2007154127A Expired - Lifetime JP4712001B2 (ja) 1995-06-05 2007-06-11 エンドトキセミアの治療及び防止に有用な置換されたリポ糖類
JP2011018401A Pending JP2011121970A (ja) 1995-06-05 2011-01-31 エンドトキセミアの治療及び防止に有用な置換されたリポ糖類

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP50186897A Expired - Lifetime JP4009318B2 (ja) 1995-06-05 1996-06-05 エンドトキセミアの治療及び防止に有用な置換されたリポ糖類

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011018401A Pending JP2011121970A (ja) 1995-06-05 2011-01-31 エンドトキセミアの治療及び防止に有用な置換されたリポ糖類

Country Status (21)

Country Link
US (8) US5750664A (enExample)
EP (1) EP0853627B1 (enExample)
JP (3) JP4009318B2 (enExample)
KR (1) KR100416335B1 (enExample)
CN (1) CN1067082C (enExample)
AT (1) ATE258185T1 (enExample)
AU (1) AU707779C (enExample)
CA (1) CA2223140C (enExample)
DE (1) DE69631376T2 (enExample)
DK (1) DK0853627T3 (enExample)
ES (1) ES2214543T3 (enExample)
HU (1) HU221342B1 (enExample)
IL (2) IL122251A0 (enExample)
MX (1) MX9709502A (enExample)
NO (1) NO310239B1 (enExample)
NZ (1) NZ312299A (enExample)
PT (1) PT853627E (enExample)
RU (1) RU2170738C2 (enExample)
TW (1) TW366345B (enExample)
WO (1) WO1996039411A1 (enExample)
ZA (1) ZA964666B (enExample)

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US20030105033A1 (en) * 2000-06-09 2003-06-05 Rossignol Daniel P. Administration of an anti-endotoxin drug by bolus or intermittent intravenous infusion
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US7727974B2 (en) * 2001-08-10 2010-06-01 Eisai R & D Management Co., Ltd. Methods of reducing the severity of mucositis
EP2338497A1 (en) 2001-08-10 2011-06-29 Eisai R&D Management Co., Ltd. Treatment and prevention of heat shock protein-associated diseases and conditions
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WO2004058788A1 (ja) * 2002-12-24 2004-07-15 Sankyo Company, Limited 右糖グルコースリピドa類縁体
KR20110120989A (ko) * 2003-01-06 2011-11-04 코릭사 코포레이션 특정의 아미노알킬 글루코사미나이드 포스페이트 화합물 및 그들의 용도
DE602004021901D1 (de) * 2003-01-28 2009-08-20 Academisch Ziekenhuis Leiden Aus ll-37 abgeleiteten peptidinhibitoren von toxinen
JP4773336B2 (ja) * 2003-02-20 2011-09-14 エーザイ・アール・アンド・ディー・マネジメント株式会社 Lpsアンタゴニストb1287およびその立体異性体の調製のための試薬および方法
JP2006519872A (ja) * 2003-03-05 2006-08-31 エーザイ株式会社 エンドトキシン関連疾患およびエンドトキシン関連状態を予防および処置するための組成物および方法
WO2005027826A2 (en) * 2003-07-14 2005-03-31 Eisai, Co, Ltd. Methods and treating severe acute respiratory syndrome
WO2005059517A2 (en) 2003-12-16 2005-06-30 University Of Massachusetts Toll-like receptor assays
CN1930180B (zh) * 2004-01-08 2010-05-26 三共株式会社 左侧葡萄糖脂a类似物
US20070292418A1 (en) * 2005-04-26 2007-12-20 Eisai Co., Ltd. Compositions and methods for immunotherapy
CN101355928B (zh) 2005-04-26 2013-05-22 卫材R&D管理株式会社 用于癌症免疫疗法的组合物和方法
WO2006138681A2 (en) * 2005-06-17 2006-12-28 University Of Rochester Methods and compositions for enhancing immune memory by blocking intrahepatic activated t cell deletion
JP5118968B2 (ja) * 2005-08-31 2013-01-16 エーザイ・アール・アンド・ディー・マネジメント株式会社 リピッドa類縁体の製造方法
KR101382162B1 (ko) * 2005-08-31 2014-04-07 에자이 알앤드디 매니지먼트 가부시키가이샤 리피드 a 유사체의 제조 방법
US7943588B2 (en) 2006-03-28 2011-05-17 Trustees Of Dartmouth College Method for preventing or treating neuropathic pain
WO2008059307A2 (en) * 2006-11-16 2008-05-22 Om Pharma Functionalized beta 1,6 glucosamine disaccharides and process for their preparation
WO2008062842A1 (fr) 2006-11-22 2008-05-29 Eisai R & D Management Co., Ltd. Sel de sodium de disaccharide et ses méthodes de production et d'utilisation
ES2392890T3 (es) * 2006-11-22 2012-12-14 Eisai R&D Management Co., Ltd. Sal sódica de un compuesto disacarídico, procedimiento para la producción de la misma y uso de la misma
EA023046B1 (ru) 2006-11-23 2016-04-29 Кадила Фармасьютикалз Лимитед Применение инактивированной нагреванием micobacterium w для снижения индуцированной tlr активности
US20110201569A1 (en) * 2009-09-16 2011-08-18 Heidi Ehrentraut Methods For Treating Myocardial Disorders
WO2011038537A1 (zh) * 2009-09-29 2011-04-07 上海南方基因科技有限公司 败血症以及败血症休克的预测、预防和治疗方法及试剂盒
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JP2012246470A (ja) 2011-05-31 2012-12-13 Sharp Corp 半導体ナノ粒子の製造方法、半導体ナノ粒子、ならびにこれを用いた蛍光体
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EP2830631B1 (en) 2012-03-28 2017-11-22 University of Maryland, Baltimore Administration of eritoran or pharmaceutically acceptable salts thereof to treat orthomyxovirus infections
WO2014113048A1 (en) * 2013-01-18 2014-07-24 Loma Linda University Compositions and methods for diagnosing and treating sepsis
JP6702862B2 (ja) 2013-07-11 2020-06-03 アルニラム ファーマスーティカルズ インコーポレイテッドAlnylam Pharmaceuticals, Inc. オリゴヌクレオチド−リガンドコンジュゲートおよびそれらの調製方法
US9584991B1 (en) * 2014-06-19 2017-02-28 Isaac S. Daniel Method of communicating and accessing social networks using interactive coded messages
CN114712383B (zh) * 2016-03-30 2024-09-24 阿尤维斯研究有限公司 新组合物和治疗方法
EP3795576B1 (en) * 2016-09-14 2023-06-07 Genomatica, Inc. 1,3-fatty diol compounds and glycosylated derivatives thereof
JP7069120B2 (ja) * 2016-09-16 2022-05-17 エーザイ・アール・アンド・ディー・マネジメント株式会社 エボラ(ebola)及びマールブルク(marburg)病を治療するためのtlr4拮抗薬としてのエリトランの使用方法
KR20210105879A (ko) * 2018-12-17 2021-08-27 에자이 알앤드디 매니지먼트 가부시키가이샤 리포좀을 포함하는 제형물
WO2021207218A1 (en) 2020-04-06 2021-10-14 Eisai R&D Management Co., Ltd. Treatment of nidovirales infection with eritoran
CN113527396B (zh) * 2020-04-17 2024-02-02 上海医药工业研究院 一种疫苗佐剂mpla的中间体、合成及应用

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