JP2011121989A5 - - Google Patents
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- Publication number
- JP2011121989A5 JP2011121989A5 JP2011045147A JP2011045147A JP2011121989A5 JP 2011121989 A5 JP2011121989 A5 JP 2011121989A5 JP 2011045147 A JP2011045147 A JP 2011045147A JP 2011045147 A JP2011045147 A JP 2011045147A JP 2011121989 A5 JP2011121989 A5 JP 2011121989A5
- Authority
- JP
- Japan
- Prior art keywords
- ethylglycine
- boro
- proline
- boroproline
- boroalanine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229940124158 Protease/peptidase inhibitor Drugs 0.000 claims 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 claims 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 description 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 2
- 0 C[C@@](B(*)OC)NC(C(*)C(C)(C)C)=O Chemical compound C[C@@](B(*)OC)NC(C(*)C(C)(C)C)=O 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- PMMYEEVYMWASQN-UHFFFAOYSA-N dl-hydroxyproline Natural products OC1C[NH2+]C(C([O-])=O)C1 PMMYEEVYMWASQN-UHFFFAOYSA-N 0.000 description 1
- 229960002591 hydroxyproline Drugs 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- NQRYJNQNLNOLGT-UHFFFAOYSA-N tetrahydropyridine hydrochloride Natural products C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 description 1
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 description 1
Images
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33351901P | 2001-11-26 | 2001-11-26 | |
| US60/333,519 | 2001-11-26 | ||
| US40553002P | 2002-08-23 | 2002-08-23 | |
| US60/405,530 | 2002-08-23 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003547426A Division JP4771661B2 (ja) | 2001-11-26 | 2002-11-26 | Post−プロリン開裂酵素の擬ペプチド性阻害剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014033295A Division JP2014139191A (ja) | 2001-11-26 | 2014-02-24 | Post−プロリン開裂酵素の擬ペプチド性阻害剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011121989A JP2011121989A (ja) | 2011-06-23 |
| JP2011121989A5 true JP2011121989A5 (enExample) | 2011-08-04 |
Family
ID=26988769
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003547426A Expired - Fee Related JP4771661B2 (ja) | 2001-11-26 | 2002-11-26 | Post−プロリン開裂酵素の擬ペプチド性阻害剤 |
| JP2011045147A Pending JP2011121989A (ja) | 2001-11-26 | 2011-03-02 | Post−プロリン開裂酵素の擬ペプチド性阻害剤 |
| JP2014033295A Abandoned JP2014139191A (ja) | 2001-11-26 | 2014-02-24 | Post−プロリン開裂酵素の擬ペプチド性阻害剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003547426A Expired - Fee Related JP4771661B2 (ja) | 2001-11-26 | 2002-11-26 | Post−プロリン開裂酵素の擬ペプチド性阻害剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014033295A Abandoned JP2014139191A (ja) | 2001-11-26 | 2014-02-24 | Post−プロリン開裂酵素の擬ペプチド性阻害剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US7727964B2 (enExample) |
| EP (2) | EP1469873A4 (enExample) |
| JP (3) | JP4771661B2 (enExample) |
| AU (1) | AU2002357767C1 (enExample) |
| CA (2) | CA2468192A1 (enExample) |
| WO (1) | WO2003045977A2 (enExample) |
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| DE60011756T2 (de) * | 1999-04-09 | 2005-07-14 | Trustees Of Tufts College, Boston | Methoden und reagentien zur bestmmung der enzym-substatspezifität und damit verbundene anwendungen |
| US6890904B1 (en) | 1999-05-25 | 2005-05-10 | Point Therapeutics, Inc. | Anti-tumor agents |
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| WO2001019866A1 (en) * | 1999-09-10 | 2001-03-22 | The University Of Sydney | Dipeptidyl peptidases |
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-
2002
- 2002-11-26 CA CA002468192A patent/CA2468192A1/en not_active Abandoned
- 2002-11-26 AU AU2002357767A patent/AU2002357767C1/en not_active Ceased
- 2002-11-26 US US10/496,706 patent/US7727964B2/en not_active Expired - Lifetime
- 2002-11-26 CA CA2837936A patent/CA2837936A1/en not_active Abandoned
- 2002-11-26 EP EP02792306A patent/EP1469873A4/en not_active Withdrawn
- 2002-11-26 EP EP10011373A patent/EP2316470A3/en not_active Withdrawn
- 2002-11-26 JP JP2003547426A patent/JP4771661B2/ja not_active Expired - Fee Related
- 2002-11-26 WO PCT/US2002/038053 patent/WO2003045977A2/en not_active Ceased
-
2010
- 2010-06-01 US US12/791,517 patent/US20110082108A1/en not_active Abandoned
-
2011
- 2011-03-02 JP JP2011045147A patent/JP2011121989A/ja active Pending
-
2014
- 2014-02-24 JP JP2014033295A patent/JP2014139191A/ja not_active Abandoned
-
2016
- 2016-02-12 US US15/043,110 patent/US9757400B2/en not_active Expired - Fee Related
-
2017
- 2017-06-19 US US15/626,254 patent/US20170333461A1/en not_active Abandoned
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