|
US4903164A
(en)
|
1988-12-08 |
1990-02-20 |
Texas Instruments Incorporated |
O-ring/back-up ring seal for high pressure transducers
|
|
CA2264819C
(en)
*
|
1996-09-04 |
2010-03-23 |
Intertrust Technologies Corp. |
Trusted infrastructure support systems, methods and techniques for secure electronic commerce, electronic transactions, commerce process control and automation, distributed computing, and rights management
|
|
CA2657247A1
(en)
|
2006-07-28 |
2008-01-31 |
Boehringer Ingelheim International Gmbh |
Compounds which modulate the cb2 receptor
|
|
AU2007287428B2
(en)
|
2006-08-24 |
2011-08-11 |
Astrazeneca Ab |
Morpholino pyrimidine derivatives useful in the treatment of proliferative disorders
|
|
US7928123B2
(en)
|
2006-09-25 |
2011-04-19 |
Boehringer Ingelheim International Gmbh |
Compounds which modulate the CB2 receptor
|
|
AU2008205252B2
(en)
*
|
2007-01-09 |
2013-02-21 |
Amgen Inc. |
Bis-aryl amide derivatives useful for the treatment of cancer
|
|
WO2008098058A1
(en)
*
|
2007-02-06 |
2008-08-14 |
Novartis Ag |
Pi 3-kinase inhibitors and methods of their use
|
|
AU2008273889B2
(en)
*
|
2007-07-09 |
2012-03-08 |
Astrazeneca Ab |
Trisubstituted pyrimidine derivatives for the treatment of proliferative diseases
|
|
CN101809002B
(zh)
|
2007-07-09 |
2013-03-27 |
阿斯利康(瑞典)有限公司 |
用于与mtor激酶和/或pi3k相关的疾病中的吗啉代嘧啶衍生物
|
|
CA2704684A1
(en)
|
2007-11-07 |
2009-05-14 |
Boehringer Ingelheim International Gmbh |
Compounds which modulate the cb2 receptor
|
|
US9029411B2
(en)
|
2008-01-25 |
2015-05-12 |
Millennium Pharmaceuticals, Inc. |
Thiophenes and uses thereof
|
|
CA2715835C
(en)
|
2008-02-29 |
2017-03-21 |
Renovis, Inc. |
Amide compounds, compositions and uses thereof
|
|
EP2418207A1
(en)
*
|
2008-05-13 |
2012-02-15 |
Boehringer Ingelheim International GmbH |
Sulfone compounds which modulate the CB2 receptor
|
|
LT2294072T
(lt)
|
2008-05-23 |
2017-06-12 |
Wyeth Llc |
Triazino junginiai, kaip p13 kinazės ir mtor inhibitoriai
|
|
ES2491522T3
(es)
|
2008-06-19 |
2014-09-08 |
Millennium Pharmaceuticals, Inc. |
Derivados de tiofeno o tiazol y su uso como inhibidores de PI3K
|
|
US8178568B2
(en)
|
2008-07-10 |
2012-05-15 |
Boehringer Ingelheim International Gmbh |
Sulfone compounds which modulate the CB2 receptor
|
|
CA2729045A1
(en)
*
|
2008-07-31 |
2010-02-04 |
Philippe Bergeron |
Pyrimidine compounds, compositions and methods of use
|
|
EP2342191B1
(en)
|
2008-09-10 |
2013-03-20 |
Mitsubishi Tanabe Pharma Corporation |
Aromatic nitrogen-containing 6-membered ring compounds and their use
|
|
JP5608655B2
(ja)
*
|
2008-09-18 |
2014-10-15 |
エヴォテック アーゲー |
P2x3受容体活性のモジュレーター
|
|
CA2737639A1
(en)
|
2008-09-25 |
2010-04-01 |
Boehringer Ingelheim International Gmbh |
Compounds which selectively modulate the cb2 receptor
|
|
TWI378933B
(en)
|
2008-10-14 |
2012-12-11 |
Daiichi Sankyo Co Ltd |
Morpholinopurine derivatives
|
|
US20110053923A1
(en)
|
2008-12-22 |
2011-03-03 |
Astrazeneca |
Chemical compounds 610
|
|
WO2010090716A1
(en)
|
2009-01-30 |
2010-08-12 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and their use as pi3k inhibitors
|
|
US8796314B2
(en)
|
2009-01-30 |
2014-08-05 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and uses thereof
|
|
US9090601B2
(en)
|
2009-01-30 |
2015-07-28 |
Millennium Pharmaceuticals, Inc. |
Thiazole derivatives
|
|
ES2529205T3
(es)
|
2009-03-13 |
2015-02-17 |
Cellzome Limited |
Derivados de pirimidina como inhibidores de mTOR
|
|
WO2010120996A1
(en)
*
|
2009-04-17 |
2010-10-21 |
Wyeth Llc |
5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine compounds, their use as mtor kinase and pi3 kinase inhibitors, and their syntheses
|
|
JP5649643B2
(ja)
*
|
2009-04-17 |
2015-01-07 |
ワイス・エルエルシー |
ピリミジン化合物、mTORキナーゼおよびPI3キナーゼ阻害剤としてのそれらの使用、ならびにそれらの合成
|
|
WO2010120991A1
(en)
*
|
2009-04-17 |
2010-10-21 |
Wyeth Llc |
5, 6, 7, 8-tetrahydropyrido[4,3-d]pyrimidine compounds, their use as mtor, pi3, and hsmg-1 kinase inhibitors, and their syntheses
|
|
US20120071475A1
(en)
*
|
2009-04-27 |
2012-03-22 |
Shionogi & Co., Ltd. |
Urea derivatives having pi3k-inhibiting activity
|
|
US8299103B2
(en)
|
2009-06-15 |
2012-10-30 |
Boehringer Ingelheim International Gmbh |
Compounds which selectively modulate the CB2 receptor
|
|
JP5756800B2
(ja)
|
2009-06-16 |
2015-07-29 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Cb2受容体を調節するアゼチジン2−カルボキサミド誘導体
|
|
LT3141252T
(lt)
|
2009-06-17 |
2018-11-12 |
Vertex Pharmaceuticals Inc. |
Gripo virusų replikacijos inhibitoriai
|
|
US20100331305A1
(en)
*
|
2009-06-24 |
2010-12-30 |
Genentech, Inc. |
Oxo-heterocycle fused pyrimidine compounds, compositions and methods of use
|
|
WO2011037795A1
(en)
|
2009-09-22 |
2011-03-31 |
Boehringer Ingelheim International Gmbh |
Compounds which selectively modulate the cb2 receptor
|
|
JP2013509444A
(ja)
|
2009-10-30 |
2013-03-14 |
アリアド・ファーマシューティカルズ・インコーポレイテッド |
がんの治療方法及び治療用組成物
|
|
EP2499143B1
(en)
|
2009-11-12 |
2016-03-16 |
F.Hoffmann-La Roche Ag |
N7-substituted purine and pyrazolopyrimidine compounds, compositions and methods of use
|
|
JP5579864B2
(ja)
|
2009-11-12 |
2014-08-27 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
N−9−置換プリン化合物、組成物及び使用の方法
|
|
US9315491B2
(en)
|
2009-12-28 |
2016-04-19 |
Development Center For Biotechnology |
Pyrimidine compounds as mTOR and PI3K inhibitors
|
|
WO2011088015A1
(en)
|
2010-01-15 |
2011-07-21 |
Boehringer Ingelheim International Gmbh |
Compounds which modulate the cb2 receptor
|
|
EP2542536B1
(en)
|
2010-03-04 |
2015-01-21 |
Cellzome Limited |
Morpholino substituted urea derivatives as mtor inhibitors
|
|
US8329735B2
(en)
|
2010-03-05 |
2012-12-11 |
Boehringer Ingelheim International Gmbh |
Tetrazole compounds which selectively modulate the CB2 receptor
|
|
SA111320519B1
(ar)
|
2010-06-11 |
2014-07-02 |
Astrazeneca Ab |
مركبات بيريميدينيل للاستخدام كمثبطات atr
|
|
WO2012012307A1
(en)
|
2010-07-22 |
2012-01-26 |
Boehringer Ingelheim International Gmbh |
Sulfonyl compounds which modulate the cb2 rece
|
|
TW201217365A
(en)
|
2010-08-11 |
2012-05-01 |
Millennium Pharm Inc |
Heteroaryls and uses thereof
|
|
WO2012021611A1
(en)
|
2010-08-11 |
2012-02-16 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and uses thereof
|
|
US8859768B2
(en)
|
2010-08-11 |
2014-10-14 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and uses thereof
|
|
SG188439A1
(en)
|
2010-10-01 |
2013-05-31 |
Novartis Ag |
Manufacturing process for pyrimidine derivatives
|
|
TW201307309A
(zh)
|
2010-10-13 |
2013-02-16 |
Millennium Pharm Inc |
雜芳基化合物及其用途
|
|
WO2012058671A1
(en)
|
2010-10-31 |
2012-05-03 |
Endo Pharmaceuticals Inc. |
Substituted quinazoline and pyrido-pyrimidine derivatives
|
|
WO2012136622A1
(en)
|
2011-04-04 |
2012-10-11 |
Cellzome Limited |
Dihydropyrrolo pyrimidine derivatives as mtor inhibitors
|
|
CN102887867B
(zh)
*
|
2011-07-21 |
2015-04-15 |
中国科学院上海药物研究所 |
一类三嗪类化合物、该化合物的制备方法及其用途
|
|
JP2014521616A
(ja)
*
|
2011-07-26 |
2014-08-28 |
グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング |
バニロイド受容体リガンドとしての置換ヘテロ芳香族ピラゾール含有カルボキサミドおよび尿素誘導体
|
|
UA118010C2
(uk)
|
2011-08-01 |
2018-11-12 |
Вертекс Фармасьютікалз Інкорпорейтед |
Інгібітори реплікації вірусів грипу
|
|
EP3255041A1
(en)
*
|
2011-09-02 |
2017-12-13 |
Purdue Pharma L.P. |
Pyrimidines as sodium channel blockers
|
|
WO2013041652A1
(en)
|
2011-09-21 |
2013-03-28 |
Cellzome Limited |
Morpholino substituted urea or carbamate derivatives as mtor inhibitors
|
|
KR20140084130A
(ko)
|
2011-10-07 |
2014-07-04 |
셀좀 리미티드 |
Mtor 억제제로서의 모르폴리노 치환된 바이사이클릭 피리미딘 우레아 또는 카르바메이트 유도체
|
|
KR20160027219A
(ko)
|
2012-05-23 |
2016-03-09 |
에프. 호프만-라 로슈 아게 |
내배엽 및 간세포를 수득하고 사용하는 조성물 및 방법
|
|
EP2803668A1
(en)
|
2013-05-17 |
2014-11-19 |
Boehringer Ingelheim International Gmbh |
Novel (cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles
|
|
US9296727B2
(en)
|
2013-10-07 |
2016-03-29 |
Vertex Pharmaceuticals Incorporated |
Methods of regioselective synthesis of 2,4-disubstituted pyrimidines
|
|
LT3068776T
(lt)
|
2013-11-13 |
2019-08-12 |
Vertex Pharmaceuticals Incorporated |
Gripo virusų replikacijos inhibitoriai
|
|
JP6618901B2
(ja)
|
2013-11-13 |
2019-12-11 |
バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated |
インフルエンザウイルスの複製の阻害剤を調製する方法
|
|
CA2948876A1
(en)
*
|
2014-05-21 |
2015-11-26 |
Allergan, Inc. |
Imidazole derivatives as formyl peptide receptor modulators
|
|
CR20170077A
(es)
|
2014-08-04 |
2017-06-26 |
Nuevolution As |
Derivados de heterociclilo opcionalmente condensados de pirimidina útiles para el tratamiento de enfermedades inflamatorias, metabólicas, oncológicas y autoinmunitarias
|
|
EP3294717B1
(en)
|
2015-05-13 |
2020-07-29 |
Vertex Pharmaceuticals Inc. |
Methods of preparing inhibitors of influenza viruses replication
|
|
EP3294735B8
(en)
|
2015-05-13 |
2022-01-05 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of influenza viruses replication
|
|
TW201815787A
(zh)
|
2016-09-23 |
2018-05-01 |
美商基利科學股份有限公司 |
磷脂醯肌醇3-激酶抑制劑
|
|
TW201813963A
(zh)
|
2016-09-23 |
2018-04-16 |
美商基利科學股份有限公司 |
磷脂醯肌醇3-激酶抑制劑
|
|
TW201825465A
(zh)
|
2016-09-23 |
2018-07-16 |
美商基利科學股份有限公司 |
磷脂醯肌醇3-激酶抑制劑
|
|
WO2018218197A2
(en)
|
2017-05-26 |
2018-11-29 |
Board Of Regents, The University Of Texas System |
Tetrahydropyrido[4,3-d]pyrimidine inhibitors of atr kinase
|
|
WO2019014618A1
(en)
|
2017-07-13 |
2019-01-17 |
Board Of Regents, University Of Texas System |
HETEROCYCLIC INHIBITORS OF KINASE ATR
|
|
JP7290627B2
(ja)
|
2017-08-17 |
2023-06-13 |
ボード オブ レジェンツ,ザ ユニバーシティ オブ テキサス システム |
Atrキナーゼの複素環式阻害剤
|
|
JP7341156B2
(ja)
|
2018-03-16 |
2023-09-08 |
ボード オブ レジェンツ,ザ ユニバーシティ オブ テキサス システム |
Atrキナーゼの複素環式阻害剤
|
|
CN118619944A
(zh)
|
2019-06-06 |
2024-09-10 |
北京泰德制药股份有限公司 |
作为atr激酶抑制剂的2,4,6-三取代的嘧啶化合物
|
|
MX2022007265A
(es)
|
2019-12-20 |
2022-09-09 |
Nuevolution As |
Compuestos activos frente a receptores nucleares.
|
|
UY38994A
(es)
|
2019-12-20 |
2021-07-30 |
Nuevolution As |
Compuestos activos frente a receptores nucleares
|
|
WO2021198956A1
(en)
|
2020-03-31 |
2021-10-07 |
Nuevolution A/S |
Compounds active towards nuclear receptors
|
|
AU2021245397A1
(en)
|
2020-03-31 |
2022-10-20 |
Nuevolution A/S |
Compounds active towards nuclear receptors
|