JP2006517563A - 置換n−アリール複素環化合物、その製造方法およびその医薬としての使用 - Google Patents
置換n−アリール複素環化合物、その製造方法およびその医薬としての使用 Download PDFInfo
- Publication number
- JP2006517563A JP2006517563A JP2006501827A JP2006501827A JP2006517563A JP 2006517563 A JP2006517563 A JP 2006517563A JP 2006501827 A JP2006501827 A JP 2006501827A JP 2006501827 A JP2006501827 A JP 2006501827A JP 2006517563 A JP2006517563 A JP 2006517563A
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- Prior art keywords
- alkyl
- independently
- group
- aryl
- nitrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 0 C*N*C(*(C(C)=C[*@@](C=C(C)[*@]1CC(*)CC1)O)O)=O Chemical compound C*N*C(*(C(C)=C[*@@](C=C(C)[*@]1CC(*)CC1)O)O)=O 0.000 description 1
- YVOMZUOXLJQTID-UHFFFAOYSA-N CC(C)(C)OC(N(C)C(CC1)CN1c(cc1)ccc1NC(N(CC1)CCC1c(cc1)ccc1Cl)=O)=O Chemical compound CC(C)(C)OC(N(C)C(CC1)CN1c(cc1)ccc1NC(N(CC1)CCC1c(cc1)ccc1Cl)=O)=O YVOMZUOXLJQTID-UHFFFAOYSA-N 0.000 description 1
- MJUYZHYERYFUQM-UHFFFAOYSA-N CC(C)(C)OC(N(C)C(CC1)CN1c(cc1)ncc1N(CC=C(C)C)C(c1ccc(C2CCCCC2)cc1)=O)=O Chemical compound CC(C)(C)OC(N(C)C(CC1)CN1c(cc1)ncc1N(CC=C(C)C)C(c1ccc(C2CCCCC2)cc1)=O)=O MJUYZHYERYFUQM-UHFFFAOYSA-N 0.000 description 1
- WKCJAGAPSQBUCU-UHFFFAOYSA-N CC(C)COc(cc1)ncc1C(Nc(cc1)ccc1N(CC1)CC1N(C)C)=O Chemical compound CC(C)COc(cc1)ncc1C(Nc(cc1)ccc1N(CC1)CC1N(C)C)=O WKCJAGAPSQBUCU-UHFFFAOYSA-N 0.000 description 1
- WAUMGCTXWHNYRZ-UHFFFAOYSA-N CC(N(C)C(CC1)CN1c(cc1)ccc1NC(C(CC1)CCC1Oc1ccccc1)=O)=O Chemical compound CC(N(C)C(CC1)CN1c(cc1)ccc1NC(C(CC1)CCC1Oc1ccccc1)=O)=O WAUMGCTXWHNYRZ-UHFFFAOYSA-N 0.000 description 1
- YYIJPAHWYLTVOR-UHFFFAOYSA-N CC(N(C)C(CC1)CN1c(cc1)ccc1NC(Nc(cc1)ccc1Oc1ccccc1)=O)=O Chemical compound CC(N(C)C(CC1)CN1c(cc1)ccc1NC(Nc(cc1)ccc1Oc1ccccc1)=O)=O YYIJPAHWYLTVOR-UHFFFAOYSA-N 0.000 description 1
- HITDNTCVKQDTEZ-UHFFFAOYSA-N CC(N(C)C(CC1)CN1c(cc1)ccc1NC(Nc(cc1)ccc1Oc1cccnc1)=O)=O Chemical compound CC(N(C)C(CC1)CN1c(cc1)ccc1NC(Nc(cc1)ccc1Oc1cccnc1)=O)=O HITDNTCVKQDTEZ-UHFFFAOYSA-N 0.000 description 1
- KPGWWOMRBYFHCK-UHFFFAOYSA-N CC(N(C)C(CC1)CN1c(cc1)ccc1NC(c(cc1)ccc1-c(cc1)ccc1F)=O)=O Chemical compound CC(N(C)C(CC1)CN1c(cc1)ccc1NC(c(cc1)ccc1-c(cc1)ccc1F)=O)=O KPGWWOMRBYFHCK-UHFFFAOYSA-N 0.000 description 1
- PQUDBCDCBVUAPZ-UHFFFAOYSA-N CC(N(C)C(CC1)CN1c(ccc(NC(N(CC1)CCC1c(cc1)ccc1Cl)=O)c1)c1F)=O Chemical compound CC(N(C)C(CC1)CN1c(ccc(NC(N(CC1)CCC1c(cc1)ccc1Cl)=O)c1)c1F)=O PQUDBCDCBVUAPZ-UHFFFAOYSA-N 0.000 description 1
- KONZOGPQGOTXKU-UHFFFAOYSA-N CC(Nc1cc(Cl)ccc1N(CC1)CCC1C(N(C)c(cc1)ccc1N(CC1)CC1N(C)C)=O)=O Chemical compound CC(Nc1cc(Cl)ccc1N(CC1)CCC1C(N(C)c(cc1)ccc1N(CC1)CC1N(C)C)=O)=O KONZOGPQGOTXKU-UHFFFAOYSA-N 0.000 description 1
- CNTQVECMGRBGAU-UHFFFAOYSA-N CN(C(CC1)CN1c(cc1)ccc1NC(Nc(cc1)ccc1OC1CCCC1)=O)C(CN1CCCCC1)=O Chemical compound CN(C(CC1)CN1c(cc1)ccc1NC(Nc(cc1)ccc1OC1CCCC1)=O)C(CN1CCCCC1)=O CNTQVECMGRBGAU-UHFFFAOYSA-N 0.000 description 1
- CNGPHJRCIUFXNA-UHFFFAOYSA-N CN(C)C(CC1)CN1c(cc1)ccc1N(C)C(C(CC1)CCN1c(nc1)ccc1Cl)=O Chemical compound CN(C)C(CC1)CN1c(cc1)ccc1N(C)C(C(CC1)CCN1c(nc1)ccc1Cl)=O CNGPHJRCIUFXNA-UHFFFAOYSA-N 0.000 description 1
- WPVCXYNKJGEXSY-UHFFFAOYSA-N CN(C)C(CC1)CN1c(cc1)ccc1NC(c(cc1)cnc1OCC1CC1)=O Chemical compound CN(C)C(CC1)CN1c(cc1)ccc1NC(c(cc1)cnc1OCC1CC1)=O WPVCXYNKJGEXSY-UHFFFAOYSA-N 0.000 description 1
- FBGGKEOWCNQBFW-UHFFFAOYSA-N CN(C)C(CC1)CN1c(cc1)ccc1NC(c1ccc(-c(ccc(F)c2)c2F)nc1)=O Chemical compound CN(C)C(CC1)CN1c(cc1)ccc1NC(c1ccc(-c(ccc(F)c2)c2F)nc1)=O FBGGKEOWCNQBFW-UHFFFAOYSA-N 0.000 description 1
- YBMDCMQPZJCAEH-UHFFFAOYSA-N CNC(CC1)CN1c1ccc(CC(N(CC2)CCC2c(cc2)ccc2Cl)=O)cc1 Chemical compound CNC(CC1)CN1c1ccc(CC(N(CC2)CCC2c(cc2)ccc2Cl)=O)cc1 YBMDCMQPZJCAEH-UHFFFAOYSA-N 0.000 description 1
- OLKWNKCUFZYAGX-UHFFFAOYSA-N O=C(Nc(cc1)ccc1N(CC1)CCC1N1CCOCC1)Nc(cc1)ccc1OC1CCCC1 Chemical compound O=C(Nc(cc1)ccc1N(CC1)CCC1N1CCOCC1)Nc(cc1)ccc1OC1CCCC1 OLKWNKCUFZYAGX-UHFFFAOYSA-N 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/20—Hypnotics; Sedatives
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Child & Adolescent Psychology (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10306250A DE10306250A1 (de) | 2003-02-14 | 2003-02-14 | Substituierte N-Arylheterozyklen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
PCT/EP2004/001342 WO2004072025A2 (de) | 2003-02-14 | 2004-02-13 | Substituierte n-arylheterozyklen, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2006517563A true JP2006517563A (ja) | 2006-07-27 |
JP2006517563A5 JP2006517563A5 (no) | 2007-02-01 |
Family
ID=32841665
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006501827A Pending JP2006517563A (ja) | 2003-02-14 | 2004-02-13 | 置換n−アリール複素環化合物、その製造方法およびその医薬としての使用 |
Country Status (29)
Country | Link |
---|---|
EP (1) | EP1597228A2 (no) |
JP (1) | JP2006517563A (no) |
KR (1) | KR20050101215A (no) |
CN (1) | CN100506792C (no) |
AR (1) | AR044496A1 (no) |
AU (1) | AU2004212145B2 (no) |
BR (1) | BRPI0407504A (no) |
CA (1) | CA2516118A1 (no) |
CO (1) | CO5690548A2 (no) |
DE (1) | DE10306250A1 (no) |
EC (1) | ECSP055967A (no) |
HR (1) | HRP20050710A2 (no) |
MA (1) | MA27735A1 (no) |
MX (1) | MXPA05008449A (no) |
MY (1) | MY139102A (no) |
NO (1) | NO20054220L (no) |
NZ (1) | NZ541823A (no) |
OA (1) | OA13027A (no) |
PA (1) | PA8595901A1 (no) |
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JP2007520466A (ja) * | 2003-12-23 | 2007-07-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 摂食障害を治療するためのmchアンタゴニスト(メラニン含有ホルモン)の形態で使用される3−(4−ピペリジン−1−イルメチル−フェニル)−プロピオン酸−フェニルアミド誘導体及び関連化合物 |
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Also Published As
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PA8595901A1 (es) | 2004-09-16 |
TNSN05194A1 (en) | 2007-06-11 |
PL378065A1 (pl) | 2006-02-20 |
MA27735A1 (fr) | 2006-02-01 |
NO20054220L (no) | 2005-10-28 |
OA13027A (en) | 2006-11-10 |
DE10306250A1 (de) | 2004-09-09 |
ZA200506369B (en) | 2006-07-26 |
PE20040952A1 (es) | 2005-02-08 |
MXPA05008449A (es) | 2006-05-25 |
CO5690548A2 (es) | 2006-10-31 |
RS20050666A (en) | 2007-12-31 |
CA2516118A1 (en) | 2004-08-26 |
RU2005128551A (ru) | 2006-02-10 |
TW200510297A (en) | 2005-03-16 |
UA86760C2 (ru) | 2009-05-25 |
AU2004212145B2 (en) | 2010-06-17 |
WO2004072025A3 (de) | 2004-12-23 |
BRPI0407504A (pt) | 2006-02-14 |
HRP20050710A2 (en) | 2006-07-31 |
KR20050101215A (ko) | 2005-10-20 |
AU2004212145A1 (en) | 2004-08-26 |
MY139102A (en) | 2009-08-28 |
UY28186A1 (es) | 2004-09-30 |
EP1597228A2 (de) | 2005-11-23 |
CN1774418A (zh) | 2006-05-17 |
ECSP055967A (es) | 2006-01-16 |
NO20054220D0 (no) | 2005-09-12 |
AR044496A1 (es) | 2005-09-14 |
NZ541823A (en) | 2009-01-31 |
CN100506792C (zh) | 2009-07-01 |
WO2004072025A2 (de) | 2004-08-26 |
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