|
PL194689B1
(pl)
|
1996-02-13 |
2007-06-29 |
Astrazeneca Uk Ltd |
Pochodne chinazoliny, ich kompozycje farmaceutyczne oraz ich zastosowania
|
|
EP0885198B1
(en)
|
1996-03-05 |
2001-12-19 |
AstraZeneca AB |
4-anilinoquinazoline derivatives
|
|
HRP970371A2
(en)
|
1996-07-13 |
1998-08-31 |
Kathryn Jane Smith |
Heterocyclic compounds
|
|
JP2001522853A
(ja)
|
1997-11-11 |
2001-11-20 |
ファイザー・プロダクツ・インク |
抗癌剤として有用なチエノピリミジンおよびチエノピリジン誘導体
|
|
GB9800569D0
(en)
|
1998-01-12 |
1998-03-11 |
Glaxo Group Ltd |
Heterocyclic compounds
|
|
EP1087970B1
(en)
|
1998-06-19 |
2004-04-28 |
Pfizer Products Inc. |
PYRROLO 2,3-d]PYRIMIDINE COMPOUNDS
|
|
PA8474101A1
(es)
|
1998-06-19 |
2000-09-29 |
Pfizer Prod Inc |
Compuestos de pirrolo [2,3-d] pirimidina
|
|
US6288082B1
(en)
|
1998-09-29 |
2001-09-11 |
American Cyanamid Company |
Substituted 3-cyanoquinolines
|
|
US6297258B1
(en)
|
1998-09-29 |
2001-10-02 |
American Cyanamid Company |
Substituted 3-cyanoquinolines
|
|
DK2253620T3
(da)
|
1998-09-29 |
2014-03-31 |
Wyeth Holdings Llc |
Substituerede 3-cyanoquinoliner som protein-tyrosinkinase-inhibitorer
|
|
NZ510551A
(en)
*
|
1998-09-29 |
2003-03-28 |
American Cyanamid Co |
Substituted 3-cyanoquinolines useful as protein tyrosine kinases inhibitors
|
|
US7625859B1
(en)
*
|
2000-02-16 |
2009-12-01 |
Oregon Health & Science University |
HER-2 binding antagonists
|
|
US7396810B1
(en)
|
2000-08-14 |
2008-07-08 |
Oregon Health Sciences University |
Compositions and methods for treating cancer by modulating HER-2 and EGF receptors
|
|
US7393823B1
(en)
|
1999-01-20 |
2008-07-01 |
Oregon Health And Science University |
HER-2 binding antagonists
|
|
JP3270834B2
(ja)
|
1999-01-27 |
2002-04-02 |
ファイザー・プロダクツ・インク |
抗がん剤として有用なヘテロ芳香族二環式誘導体
|
|
UA71945C2
(en)
|
1999-01-27 |
2005-01-17 |
Pfizer Prod Inc |
Substituted bicyclic derivatives being used as anticancer agents
|
|
GB9914486D0
(en)
|
1999-06-21 |
1999-08-18 |
Smithkline Beecham Plc |
Medicaments
|
|
ATE377597T1
(de)
|
1999-07-09 |
2007-11-15 |
Glaxo Group Ltd |
Anilinochinazoline als protein-tyrosin- kinasehemmer
|
|
US6933299B1
(en)
|
1999-07-09 |
2005-08-23 |
Smithkline Beecham Corporation |
Anilinoquinazolines as protein tyrosine kinase inhibitors
|
|
GB9917406D0
(en)
|
1999-07-23 |
1999-09-22 |
Smithkline Beecham Plc |
Compounds
|
|
GB9917408D0
(en)
|
1999-07-23 |
1999-09-22 |
Smithkline Beecham Plc |
Compounds
|
|
US6432979B1
(en)
|
1999-08-12 |
2002-08-13 |
American Cyanamid Company |
Method of treating or inhibiting colonic polyps and colorectal cancer
|
|
JP3522727B2
(ja)
|
1999-11-05 |
2004-04-26 |
アストラゼネカ アクチボラグ |
Ｖｅｇｆ阻害剤としてのキナゾリン誘導体
|
|
UA74803C2
(uk)
|
1999-11-11 |
2006-02-15 |
Осі Фармасьютікалз, Інк. |
Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
|
|
UA75055C2
(uk)
*
|
1999-11-30 |
2006-03-15 |
Пфайзер Продактс Інк. |
Похідні бензоімідазолу, що використовуються як антипроліферативний засіб, фармацевтична композиція на їх основі
|
|
CN1195755C
(zh)
|
1999-12-10 |
2005-04-06 |
辉瑞产品公司 |
吡咯并[2,3－d]嘧啶化合物
|
|
US6610688B2
(en)
|
1999-12-21 |
2003-08-26 |
Sugen, Inc. |
4-substituted 7-aza-indolin-2-ones and their use as protein kinase inhibitors
|
|
SK17342002A3
(sk)
|
2000-06-26 |
2004-06-08 |
Pfizer Products Inc. |
Derivát pyrolo[2,3-d]pyrimidínu ako činidlo potlačujúce imunitu
|
|
CZ300945B6
(cs)
*
|
2000-06-30 |
2009-09-23 |
Glaxo Group Limited |
Zpusob prípravy 5-(6-chinazolinyl)-furan-2-karbaldehydu
|
|
EP1305308B1
(en)
*
|
2000-07-26 |
2006-12-20 |
Smithkline Beecham Plc |
Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity
|
|
MXPA03000874A
(es)
*
|
2000-08-09 |
2003-06-06 |
Astrazeneca Ab |
Compuestos quimicos.
|
|
PL359920A1
(en)
|
2000-09-20 |
2004-09-06 |
Merck Patent Gmbh |
4-amino-quinazolines
|
|
MX242553B
(es)
|
2000-10-20 |
2006-12-06 |
Eisai Co Ltd |
Derivados aromaticos que contienen nitrogeno.
|
|
MX337162B
(es)
|
2001-01-05 |
2016-02-15 |
Pfizer |
Anticuerpos contra el receptor del factor de crecimiento similar a insulina.
|
|
ATE290882T1
(de)
*
|
2001-01-16 |
2005-04-15 |
Glaxo Group Ltd |
Pharmazeutische mischung gegen krebs, die ein 4- chinazolinamin in kombination mit paclitaxel, carboplatin or vinorelbine enthält
|
|
GB0101577D0
(en)
|
2001-01-22 |
2001-03-07 |
Smithkline Beecham Plc |
Compounds
|
|
EP1249451B1
(en)
*
|
2001-04-13 |
2006-06-21 |
Pfizer Products Inc. |
Bicyclic-substituted 4-amino-pyridopyrimidine derivatives
|
|
GB0112834D0
(en)
|
2001-05-25 |
2001-07-18 |
Smithkline Beecham Plc |
Medicaments
|
|
GB0112836D0
(en)
|
2001-05-25 |
2001-07-18 |
Smithkline Beecham Plc |
Medicaments
|
|
US7301023B2
(en)
|
2001-05-31 |
2007-11-27 |
Pfizer Inc. |
Chiral salt resolution
|
|
AU2002345792A1
(en)
|
2001-06-21 |
2003-01-08 |
Pfizer Inc. |
Thienopyridine and thienopyrimidine anticancer agents
|
|
US7829566B2
(en)
|
2001-09-17 |
2010-11-09 |
Werner Mederski |
4-amino-quinazolines
|
|
AR039067A1
(es)
|
2001-11-09 |
2005-02-09 |
Pfizer Prod Inc |
Anticuerpos para cd40
|
|
DE60320933D1
(de)
|
2002-01-10 |
2008-06-26 |
Bayer Healthcare Ag |
Rho-kinase inhibitoren
|
|
KR20040085151A
(ko)
*
|
2002-01-17 |
2004-10-07 |
뉴로젠 코포레이션 |
캡사이신 조절자로서의 치환된 퀴나졸린-4-일 아민 유사체
|
|
WO2003062225A1
(en)
|
2002-01-23 |
2003-07-31 |
Bayer Pharmaceuticals Corporation |
Pyrimidine derivatives as rho-kinase inhibitors
|
|
JP4423043B2
(ja)
|
2002-01-23 |
2010-03-03 |
バイエル ファーマセチカル コーポレーション |
Ｒｈｏ−キナーゼ阻害剤
|
|
EP1470125A1
(en)
|
2002-01-29 |
2004-10-27 |
Glaxo Group Limited |
Aminopiperidine derivatives
|
|
AU2003239302A1
(en)
|
2002-01-29 |
2003-09-02 |
Glaxo Group Limited |
Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
|
|
EP1483268A2
(en)
|
2002-03-01 |
2004-12-08 |
Pfizer Inc. |
Indolyl-urea derivatives of thienopyridines useful as anti-angiogenic agents
|
|
WO2003086467A1
(en)
*
|
2002-04-08 |
2003-10-23 |
Smithkline Beecham Corporation |
Cancer treatment method comprising administering an erb-family inhibitor and a raf and/or ras inhibitor
|
|
UA77303C2
(en)
|
2002-06-14 |
2006-11-15 |
Pfizer |
Derivatives of thienopyridines substituted by benzocondensed heteroarylamide useful as therapeutic agents, pharmaceutical compositions and methods for their use
|
|
US20050239784A1
(en)
*
|
2002-07-15 |
2005-10-27 |
Lacrampe Jean F A |
3-Phenyl analogs of toxoflavine as kinase inhibitors
|
|
CA2491191C
(en)
|
2002-07-15 |
2014-02-04 |
Exelixis, Inc. |
Receptor-type kinase modulators and methods of use
|
|
EP1542989B1
(en)
*
|
2002-07-31 |
2007-04-18 |
Critical Outcome Technologies, Inc. |
Protein tyrosine kinase inhibitors
|
|
EP1551824B1
(en)
*
|
2002-10-09 |
2007-12-12 |
Critical Outcome Technologies, Inc. |
Protein tyrosine kinase inhibitors
|
|
FR2846657B1
(fr)
*
|
2002-11-05 |
2004-12-24 |
Servier Lab |
Nouveaux composes pyridopyrimidinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
JP4611745B2
(ja)
|
2002-11-20 |
2011-01-12 |
アレイ バイオファーマ、インコーポレイテッド |
ＥｒｂＢ２及びＥＧＦＲ阻害剤としてのシアノグアニジン及びシアノアミジン
|
|
NZ539901A
(en)
|
2002-11-26 |
2007-09-28 |
Pfizer Prod Inc |
Method of treatment of transplant rejection
|
|
KR20050084292A
(ko)
*
|
2002-12-13 |
2005-08-26 |
뉴로젠 코포레이션 |
캅사이신 수용체 조절체로서 2-치환된 퀴나졸린-4-일아민동족체
|
|
DK1585743T3
(da)
|
2002-12-19 |
2007-09-17 |
Pfizer |
2-(H-indazol-6-ylamino)-benzamid forbindelser som protein kinase inhibitorer, nyttige til behandling opthalmiske sygdomme
|
|
ATE458731T1
(de)
|
2002-12-20 |
2010-03-15 |
Pfizer Prod Inc |
Pyrimidin-derivate zur behandlung von anormalem zellwachstum
|
|
ES2502490T3
(es)
|
2003-02-26 |
2014-10-03 |
Sugen, Inc. |
Compuestos aminoheteroarílicos como inhibidores de proteín quinasas
|
|
JP2007525187A
(ja)
*
|
2003-05-16 |
2007-09-06 |
レセプター・バイオロジクス・インコーポレイテッド |
イントロン融合タンパク質、ならびにその同定方法および使用方法
|
|
TW200510373A
(en)
*
|
2003-07-14 |
2005-03-16 |
Neurogen Corp |
Substituted quinolin-4-ylamine analogues
|
|
US7329664B2
(en)
*
|
2003-07-16 |
2008-02-12 |
Neurogen Corporation |
Substituted (7-pyridyl-4-phenylamino-quinazolin-2-yl)-methanol analogues
|
|
US7008953B2
(en)
|
2003-07-30 |
2006-03-07 |
Agouron Pharmaceuticals, Inc. |
3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
|
|
WO2005011607A2
(en)
*
|
2003-08-01 |
2005-02-10 |
Smithkline Beecham Corporation |
Treatment of cancers expressing p95 erbb2
|
|
HN2004000285A
(es)
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
|
US20050038047A1
(en)
*
|
2003-08-14 |
2005-02-17 |
Edwards Paul John |
Azaquinazoline derivatives
|
|
WO2005021554A1
(en)
|
2003-08-29 |
2005-03-10 |
Pfizer Inc. |
Thienopyridine-phenylacet amides and their derivatives useful as new anti-angiogenic agents
|
|
CA2537883A1
(en)
*
|
2003-09-09 |
2005-03-17 |
Neurogen Corporation |
Substituted bicyclic quinazolin-4-ylamine derivatives
|
|
AR045563A1
(es)
|
2003-09-10 |
2005-11-02 |
Warner Lambert Co |
Anticuerpos dirigidos a m-csf
|
|
CA2744997A1
(en)
|
2003-09-26 |
2005-04-07 |
Exelixis, Inc. |
C-met modulators and method of use
|
|
US7683172B2
(en)
|
2003-11-11 |
2010-03-23 |
Eisai R&D Management Co., Ltd. |
Urea derivative and process for preparing the same
|
|
GB0326459D0
(en)
|
2003-11-13 |
2003-12-17 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
CA2547283C
(en)
*
|
2003-11-26 |
2010-11-09 |
Pfizer Products Inc. |
Aminopyrazole derivatives as gsk-3 inhibitors
|
|
CA2551508C
(en)
|
2003-12-23 |
2011-08-09 |
Pfizer Inc. |
Novel quinoline derivatives
|
|
TW200529846A
(en)
|
2004-02-20 |
2005-09-16 |
Wyeth Corp |
3-quinolinecarbonitrile protein kinase inhibitors
|
|
EP1746999B1
(en)
|
2004-05-06 |
2011-11-16 |
Warner-Lambert Company LLC |
4-phenylamino-quinazolin-6-yl-amides
|
|
JP2008506366A
(ja)
*
|
2004-05-14 |
2008-03-06 |
レセプター バイオロジックス インコーポレイテッド |
細胞表面受容体アイソフォームならびにその同定および使用方法
|
|
WO2005120509A1
(en)
*
|
2004-06-04 |
2005-12-22 |
Amphora Discovery Corporation |
Quinoline- and isoquinoline-based compounds exhibiting atp-utilizing enzyme inhibitory activity, and compositions, and uses thereof
|
|
JP2008506681A
(ja)
|
2004-07-16 |
2008-03-06 |
ファイザー・プロダクツ・インク |
抗ｉｇｆ−１ｒ抗体を用いる非血液性の悪性腫瘍の併用療法
|
|
EA013678B1
(ru)
|
2004-08-26 |
2010-06-30 |
Пфайзер Инк. |
Энантиомерно чистые аминогетероарильные соединения в качестве ингибиторов протеинкиназы
|
|
WO2006030826A1
(ja)
|
2004-09-17 |
2006-03-23 |
Eisai R & D Management Co., Ltd. |
医薬組成物
|
|
US20080206231A1
(en)
*
|
2004-10-05 |
2008-08-28 |
Oregon Health And Science University |
Compositions and Methods for Treating Disease
|
|
TW200621251A
(en)
|
2004-10-12 |
2006-07-01 |
Neurogen Corp |
Substituted biaryl quinolin-4-ylamine analogues
|
|
DE602005026865D1
(de)
|
2004-12-14 |
2011-04-21 |
Astrazeneca Ab |
Pyrazolopyrimidinverbindungen als antitumormittel
|
|
GB0428475D0
(en)
*
|
2004-12-30 |
2005-02-02 |
4 Aza Bioscience Nv |
Pyrido(3,2-D)pyrimidine derivatives and pharmaceutical compositions useful as medicines for the treatment of autoimmune disorders
|
|
BRPI0609655A2
(pt)
|
2005-03-31 |
2010-03-16 |
Agensys Inc |
anticorpos e moléculas relacionadas que ligam-se às proteìnas 161p2f10b
|
|
KR101203328B1
(ko)
|
2005-04-26 |
2012-11-20 |
화이자 인코포레이티드 |
Ｐ-카드헤린 항체
|
|
US20090170769A1
(en)
*
|
2005-05-13 |
2009-07-02 |
Pei Jin |
Cell surface receptor isoforms and methods of identifying and using the same
|
|
AU2006261607A1
(en)
*
|
2005-06-24 |
2006-12-28 |
Gilead Sciences, Inc. |
Pyrido(3,2-d)pyrimidines and pharmaceutical compositions useful for treating hepatitis C.
|
|
EP2281901B1
(en)
|
2005-08-02 |
2013-11-27 |
Eisai R&D Management Co., Ltd. |
Anti-tumour pharmaceutical composition with angiogenesis inhibitors
|
|
TW200804345A
(en)
|
2005-08-30 |
2008-01-16 |
Novartis Ag |
Substituted benzimidazoles and methods of preparation
|
|
CN101517068B
(zh)
|
2005-09-07 |
2017-02-08 |
安进弗里蒙特公司 |
活化素受体样激酶‑1的人单克隆抗体
|
|
EP1928861B1
(en)
|
2005-09-20 |
2010-11-17 |
AstraZeneca AB |
4- (ih-indazol-5-yl-amino)-quinazoline compounds as erbb receptor tyrosine kinase inhibitors for the treatment of cancer
|
|
JP5055284B2
(ja)
|
2005-09-20 |
2012-10-24 |
オーエスアイ・フアーマシユーテイカルズ・エル・エル・シー |
インシュリン様成長因子−１受容体キナーゼ阻害剤に対する抗癌応答を予測する生物学的マーカー
|
|
ES2395386T3
(es)
|
2005-12-21 |
2013-02-12 |
Abbott Laboratories |
Compuestos antivirales
|
|
ATE475660T1
(de)
|
2005-12-21 |
2010-08-15 |
Abbott Lab |
Antivirale verbindungen
|
|
US7910595B2
(en)
|
2005-12-21 |
2011-03-22 |
Abbott Laboratories |
Anti-viral compounds
|
|
JP5188988B2
(ja)
|
2006-02-10 |
2013-04-24 |
トランステック ファーマ，インコーポレイティド |
ベンゾアゾール誘導体、組成物、及びオーロラキナーゼ阻害剤としての使用方法
|
|
US20090036429A1
(en)
*
|
2006-02-17 |
2009-02-05 |
Ohler Norman E |
Hydroxypiperidine Derivatives and Uses Thereof
|
|
EA200802058A1
(ru)
|
2006-05-09 |
2009-06-30 |
Пфайзер Продактс Инк. |
Производные циклоалкиламинокислот и их фармацевтические композиции
|
|
AU2007252506C1
(en)
|
2006-05-18 |
2012-07-19 |
Eisai R & D Management Co., Ltd. |
Antitumor agent for thyroid cancer
|
|
KR100760148B1
(ko)
|
2006-07-19 |
2007-09-18 |
주식회사 엘지생활건강 |
알파-리포산을 안정화시킨 화장료 조성물
|
|
US8338435B2
(en)
*
|
2006-07-20 |
2012-12-25 |
Gilead Sciences, Inc. |
Substituted pyrido(3,2-D) pyrimidines and pharmaceutical compositions for treating viral infections
|
|
US8492378B2
(en)
|
2006-08-03 |
2013-07-23 |
Takeda Pharmaceutical Company Limited |
GSK-3β inhibitor
|
|
EP2065372B1
(en)
|
2006-08-28 |
2012-11-28 |
Eisai R&D Management Co., Ltd. |
Antitumor agent for undifferentiated gastric cancer
|
|
WO2008067119A2
(en)
*
|
2006-11-27 |
2008-06-05 |
Smithkline Beecham Corporation |
Novel compounds
|
|
TWI399380B
(zh)
|
2006-12-20 |
2013-06-21 |
Abbott Lab |
抗病毒化合物
|
|
TW200840584A
(en)
*
|
2006-12-26 |
2008-10-16 |
Gilead Sciences Inc |
Pyrido(3,2-d)pyrimidines useful for treating viral infections
|
|
WO2008077649A1
(en)
*
|
2006-12-26 |
2008-07-03 |
Gilead Sciences, Inc. |
Pyrido(3,2-d)pyrimidines useful for treating viral infectons
|
|
US8637531B2
(en)
*
|
2006-12-26 |
2014-01-28 |
Gilead Sciences, Inc. |
Pyrido(3,2-d)pyridmidines useful for treating viral infections
|
|
US8138191B2
(en)
|
2007-01-11 |
2012-03-20 |
Critical Outcome Technologies Inc. |
Inhibitor compounds and cancer treatment methods
|
|
CA2673683C
(en)
|
2007-01-11 |
2014-07-29 |
Critical Outcome Technologies, Inc. |
Compounds and method for treatment of cancer
|
|
CN101600694A
(zh)
|
2007-01-29 |
2009-12-09 |
卫材R&D管理有限公司 |
未分化型胃癌治疗用组合物
|
|
CA2684470C
(en)
*
|
2007-04-16 |
2016-02-09 |
Hutchison Medipharma Enterprises Limited |
Pyrimidine derivatives
|
|
JP4782239B2
(ja)
|
2007-04-18 |
2011-09-28 |
ファイザー・プロダクツ・インク |
異常細胞増殖治療のためのスルホニルアミド誘導体
|
|
JP2010527915A
(ja)
*
|
2007-04-26 |
2010-08-19 |
アバロン ファーマシューティカルズ，インコーポレイテッド |
多重環化合物及びその用途
|
|
MX2009012117A
(es)
*
|
2007-05-09 |
2009-11-23 |
Pfizer |
Composiciones y derivados heterociclicos sustituidos y su uso farmaceutico como antibacterianos.
|
|
EP2185574B1
(en)
|
2007-09-07 |
2013-05-08 |
Agensys, Inc. |
Antibodies and related molecules that bind to 24p4c12 proteins
|
|
EA018716B1
(ru)
|
2007-10-29 |
2013-10-30 |
Натко Фарма Лимитед |
Новые 4-(тетразол-5-ил) хиназолиновые производные в качестве противораковых средств
|
|
AU2008325608B2
(en)
|
2007-11-09 |
2013-03-14 |
Eisai R & D Management Co., Ltd. |
Combination of anti-angiogenic substance and anti-tumor platinum complex
|
|
WO2009079797A1
(en)
|
2007-12-26 |
2009-07-02 |
Critical Outcome Technologies, Inc. |
Compounds and method for treatment of cancer
|
|
WO2009111644A2
(en)
*
|
2008-03-05 |
2009-09-11 |
The Regents Of The University Of Michigan |
Compositions and methods for diagnosing and treating pancreatic cancer
|
|
CN102099357B
(zh)
*
|
2008-04-23 |
2014-07-02 |
里格尔药品股份有限公司 |
用于治疗代谢障碍的甲酰胺化合物
|
|
US7829574B2
(en)
*
|
2008-05-09 |
2010-11-09 |
Hutchison Medipharma Enterprises Limited |
Substituted quinazoline compounds and their use in treating angiogenesis-related diseases
|
|
US8426430B2
(en)
*
|
2008-06-30 |
2013-04-23 |
Hutchison Medipharma Enterprises Limited |
Quinazoline derivatives
|
|
US8536187B2
(en)
*
|
2008-07-03 |
2013-09-17 |
Gilead Sciences, Inc. |
2,4,6-trisubstituted pyrido(3,2-d)pyrimidines useful for treating viral infections
|
|
EP2330909B1
(en)
*
|
2008-08-12 |
2013-09-18 |
GlaxoSmithKline LLC |
Chemical compounds
|
|
BRPI0917459B1
(pt)
|
2008-08-20 |
2017-09-12 |
Zoetis Services Llc |
N-methyl-1- [trans-4- [methyl (7h-pyrrol [2,3-d] pyridol [2,3-d] pyrimidine compounds, use of these in therapy and crystalline a form of n-methyl- pyrimidin-4-yl) amino] cyclohexyl} methanosulphonamide
|
|
TW201008933A
(en)
*
|
2008-08-29 |
2010-03-01 |
Hutchison Medipharma Entpr Ltd |
Pyrimidine compounds
|
|
AR073680A1
(es)
*
|
2008-09-26 |
2010-11-24 |
Takeda Pharmaceutical |
Prevencion y tratamiento de cancer con la mutacion del gen ras. composicion farmaceutica. uso.
|
|
WO2010036928A1
(en)
*
|
2008-09-26 |
2010-04-01 |
Takeda Pharmaceutical Company Limited |
Prevention and treatment of cancer with lkb1 non-expression (deletion or mutation)
|
|
JP5836125B2
(ja)
|
2008-10-16 |
2015-12-24 |
ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション |
高分子量メラノーマ関連抗原に対する完全ヒト抗体およびその使用
|
|
MX2011004824A
(es)
|
2008-11-07 |
2012-01-12 |
Triact Therapeutics Inc |
Uso de derivados de butano catecólico en terapia contra el cáncer.
|
|
CN101735200B
(zh)
*
|
2008-11-17 |
2013-01-02 |
岑均达 |
喹唑啉类化合物
|
|
DK2387563T4
(da)
|
2009-01-16 |
2022-07-18 |
Exelixis Inc |
Malatsalt af n-(4-{ [ 6, 7-bis(methyloxy)quinolin-4-yl]oxy}phenyl-n'-(4-fluorphenyl)cyclopropan-1,1-dicarboxamid, og krystallinske former deraf til behandling af cancer
|
|
WO2010090764A1
(en)
|
2009-02-09 |
2010-08-12 |
Supergen, Inc. |
Pyrrolopyrimidinyl axl kinase inhibitors
|
|
EP2400985A2
(en)
|
2009-02-25 |
2012-01-04 |
OSI Pharmaceuticals, LLC |
Combination of an either an anti-igf-1r antibody or an igf binding protein and a small molecule igf-1r kinase inhibitor
|
|
JP2012519170A
(ja)
|
2009-02-26 |
2012-08-23 |
オーエスアイ・ファーマシューティカルズ，エルエルシー |
生体内の腫瘍細胞のｅｍｔステータスをモニターするためのｉｎｓｉｔｕ法
|
|
WO2010099138A2
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
|
EP2401614A1
(en)
|
2009-02-27 |
2012-01-04 |
OSI Pharmaceuticals, LLC |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
|
WO2010099364A2
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
|
WO2010098866A1
(en)
|
2009-02-27 |
2010-09-02 |
Supergen, Inc. |
Cyclopentathiophene/cyclohexathiophene dna methyltransferase inhibitors
|
|
US20120064072A1
(en)
|
2009-03-18 |
2012-03-15 |
Maryland Franklin |
Combination Cancer Therapy Comprising Administration of an EGFR Inhibitor and an IGF-1R Inhibitor
|
|
WO2011008696A2
(en)
|
2009-07-13 |
2011-01-20 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of cancer
|
|
WO2011014726A1
(en)
|
2009-07-31 |
2011-02-03 |
Osi Pharmaceuticals, Inc. |
Mtor inhibitor and angiogenesis inhibitor combination therapy
|
|
UA108618C2
(uk)
|
2009-08-07 |
2015-05-25 |
|
Застосування c-met-модуляторів в комбінації з темозоломідом та/або променевою терапією для лікування раку
|
|
EP2473500A2
(en)
|
2009-09-01 |
2012-07-11 |
Pfizer Inc. |
Benzimidazole derivatives
|
|
KR20120105423A
(ko)
|
2009-09-11 |
2012-09-25 |
제넨테크, 인크. |
항암제에 반응할 증가된 가능성을 갖는 환자를 확인하는 방법
|
|
WO2011033006A1
(en)
|
2009-09-17 |
2011-03-24 |
F. Hoffmann-La Roche Ag |
Methods and compositions for diagnostics use in cancer patients
|
|
KR101690358B1
(ko)
|
2009-10-29 |
2017-01-09 |
제노스코 |
키나아제 억제제
|
|
CA2780875A1
(en)
|
2009-11-13 |
2011-05-19 |
Pangaea Biotech, S.L. |
Molecular biomarkers for predicting response to tyrosine kinase inhibitors in lung cancer
|
|
WO2011073521A1
(en)
|
2009-12-15 |
2011-06-23 |
Petri Salven |
Methods for enriching adult-derived endothelial progenitor cells and uses thereof
|
|
SG10201406805RA
(en)
|
2010-02-12 |
2014-11-27 |
Pfizer |
Salts and polymorphs of 8-fluoro-2-{4-[(methylamino}methyl]phenyl}-1,3,4,5-tetrahydro-6h-azepino[5,4,3-cd]indol-6-one
|
|
WO2011109572A2
(en)
|
2010-03-03 |
2011-09-09 |
OSI Pharmaceuticals, LLC |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
|
|
US20110217309A1
(en)
|
2010-03-03 |
2011-09-08 |
Buck Elizabeth A |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
|
|
CA2794952C
(en)
|
2010-04-01 |
2018-05-15 |
Critical Outcome Technologies Inc. |
Compounds and method for treatment of hiv
|
|
WO2011153224A2
(en)
|
2010-06-02 |
2011-12-08 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of cancer
|
|
JP2013538042A
(ja)
|
2010-06-16 |
2013-10-10 |
ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション |
エンドプラスミンに対する抗体およびその使用
|
|
RU2598852C2
(ru)
|
2010-06-23 |
2016-09-27 |
Ханми Сайенс Ко., Лтд. |
Новые конденсированные пиримидиновые производные для ингибирования тирозинкиназной активности
|
|
KR101677790B1
(ko)
|
2010-06-25 |
2016-11-18 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
키나제 저해 작용을 갖는 화합물의 병용에 의한 항종양제
|
|
CN104730243A
(zh)
|
2010-07-19 |
2015-06-24 |
霍夫曼-拉罗奇有限公司 |
鉴定响应抗癌疗法的可能性升高的患者的方法
|
|
JP2013538338A
(ja)
|
2010-07-19 |
2013-10-10 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
抗癌治療への応答可能性の増大した患者を同定する方法
|
|
ES2979168T3
(es)
|
2010-07-23 |
2024-09-24 |
Univ Boston |
Inhibidores anti-DEspR como productos terapéuticos para inhibición de angiogénesis patológica e invasividad de células tumorales y para imagenología molecular y administración dirigida
|
|
WO2012042421A1
(en)
|
2010-09-29 |
2012-04-05 |
Pfizer Inc. |
Method of treating abnormal cell growth
|
|
WO2012052948A1
(en)
|
2010-10-20 |
2012-04-26 |
Pfizer Inc. |
Pyridine- 2- derivatives as smoothened receptor modulators
|
|
EP2468883A1
(en)
|
2010-12-22 |
2012-06-27 |
Pangaea Biotech S.L. |
Molecular biomarkers for predicting response to tyrosine kinase inhibitors in lung cancer
|
|
US9134297B2
(en)
|
2011-01-11 |
2015-09-15 |
Icahn School Of Medicine At Mount Sinai |
Method and compositions for treating cancer and related methods
|
|
WO2012116040A1
(en)
|
2011-02-22 |
2012-08-30 |
OSI Pharmaceuticals, LLC |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors in hepatocellular carcinoma
|
|
EP2492688A1
(en)
|
2011-02-23 |
2012-08-29 |
Pangaea Biotech, S.A. |
Molecular biomarkers for predicting response to antitumor treatment in lung cancer
|
|
WO2012129145A1
(en)
|
2011-03-18 |
2012-09-27 |
OSI Pharmaceuticals, LLC |
Nscle combination therapy
|
|
WO2012142164A1
(en)
|
2011-04-12 |
2012-10-18 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Human monoclonal antibodies that bind insulin-like growth factor (igf) i and ii
|
|
KR101762999B1
(ko)
|
2011-04-18 |
2017-07-28 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
종양 치료제
|
|
CA2830972C
(en)
|
2011-04-19 |
2018-11-20 |
Pfizer Inc. |
Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer
|
|
JP2014519813A
(ja)
|
2011-04-25 |
2014-08-21 |
オーエスアイ・ファーマシューティカルズ，エルエルシー |
癌薬剤発見、診断、および治療におけるｅｍｔ遺伝子シグネチャーの使用
|
|
US9945862B2
(en)
|
2011-06-03 |
2018-04-17 |
Eisai R&D Management Co., Ltd. |
Biomarkers for predicting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds
|
|
JP6105578B2
(ja)
|
2011-07-21 |
2017-03-29 |
トレロ ファーマシューティカルズ， インコーポレイテッド |
複素環式プロテインキナーゼ阻害剤
|
|
CA2845179A1
(en)
|
2011-08-31 |
2013-03-07 |
Genentech, Inc. |
Diagnostic markers
|
|
KR20140059246A
(ko)
|
2011-09-22 |
2014-05-15 |
화이자 인코포레이티드 |
피롤로피리미딘 및 퓨린 유도체
|
|
EP2761025A1
(en)
|
2011-09-30 |
2014-08-06 |
Genentech, Inc. |
Diagnostic methylation markers of epithelial or mesenchymal phenotype and response to egfr kinase inhibitor in tumours or tumour cells
|
|
WO2013050725A1
(en)
|
2011-10-04 |
2013-04-11 |
King's College London |
Ige anti -hmw-maa antibody
|
|
BR112014011115A2
(pt)
|
2011-11-08 |
2017-06-13 |
Pfizer |
métodos para tratamento de distúrbios inflamatórios usando anticorpos anti-m-csf
|
|
WO2013152252A1
(en)
|
2012-04-06 |
2013-10-10 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
|
WO2013190089A1
(en)
|
2012-06-21 |
2013-12-27 |
Pangaea Biotech, S.L. |
Molecular biomarkers for predicting outcome in lung cancer
|
|
DK2909181T3
(da)
|
2012-10-16 |
2017-11-20 |
Tolero Pharmaceuticals Inc |
PKM2-modulatorer og fremgangsmåder til anvendelse deraf
|
|
US9260426B2
(en)
|
2012-12-14 |
2016-02-16 |
Arrien Pharmaceuticals Llc |
Substituted 1H-pyrrolo [2, 3-b] pyridine and 1H-pyrazolo [3, 4-b] pyridine derivatives as salt inducible kinase 2 (SIK2) inhibitors
|
|
CA2889866A1
(en)
|
2012-12-21 |
2014-06-26 |
Eisai R&D Management Co., Ltd. |
Amorphous form of quinoline derivative, and method for producing same
|
|
US9834575B2
(en)
|
2013-02-26 |
2017-12-05 |
Triact Therapeutics, Inc. |
Cancer therapy
|
|
US10202356B2
(en)
|
2013-03-14 |
2019-02-12 |
Tolero Pharmaceuticals, Inc. |
JAK2 and ALK2 inhibitors and methods for their use
|
|
PL2970211T3
(pl)
*
|
2013-03-15 |
2018-01-31 |
Quanticel Pharmaceuticals Inc |
Inhibitory demetylazy histonowej
|
|
WO2014147246A1
(en)
|
2013-03-21 |
2014-09-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method and pharmaceutical composition for use in the treatment of chronic liver diseases associated with a low hepcidin expression
|
|
US9206188B2
(en)
|
2013-04-18 |
2015-12-08 |
Arrien Pharmaceuticals Llc |
Substituted pyrrolo[2,3-b]pyridines as ITK and JAK inhibitors
|
|
NZ714049A
(en)
|
2013-05-14 |
2020-05-29 |
Eisai R&D Man Co Ltd |
Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds
|
|
TW201534597A
(zh)
|
2013-06-20 |
2015-09-16 |
Ab Science |
作為選擇性蛋白質激酶抑制劑之苯并咪唑衍生物
|
|
EP3044593A4
(en)
|
2013-09-09 |
2017-05-17 |
Triact Therapeutics, Inc. |
Cancer therapy
|
|
UA115388C2
(uk)
|
2013-11-21 |
2017-10-25 |
Пфайзер Інк. |
2,6-заміщені пуринові похідні та їх застосування в лікуванні проліферативних захворювань
|
|
PT3126528T
(pt)
|
2014-04-04 |
2021-09-09 |
Crown Bioscience Inc Taicang |
Métodos para determinar a responsividade a inibidores de mek/erk
|
|
WO2015155624A1
(en)
|
2014-04-10 |
2015-10-15 |
Pfizer Inc. |
Dihydropyrrolopyrimidine derivatives
|
|
US20170027940A1
(en)
|
2014-04-10 |
2017-02-02 |
Stichting Het Nederlands Kanker Instituut |
Method for treating cancer
|
|
EA033919B1
(ru)
|
2014-04-30 |
2019-12-10 |
Пфайзер Инк. |
Соединённые циклоалкилом дигетероциклические производные
|
|
WO2016001789A1
(en)
|
2014-06-30 |
2016-01-07 |
Pfizer Inc. |
Pyrimidine derivatives as pi3k inhibitors for use in the treatment of cancer
|
|
JP6811706B2
(ja)
|
2014-07-31 |
2021-01-13 |
ザ ホンコン ユニヴァーシティ オブ サイエンス アンド テクノロジー |
Ｅｐｈａ４に対するヒトモノクローナル抗体及びそれらの使用
|
|
HRP20221047T1
(hr)
|
2014-08-28 |
2022-11-11 |
Eisai R&D Management Co., Ltd. |
Derivat kinolina visoke čistoće i postupak za njegovu proizvodnju
|
|
ES2746839T3
(es)
|
2014-12-18 |
2020-03-09 |
Pfizer |
Derivados de pirimidina y triazina y su uso como inhibidores de AXL
|
|
AU2015371312B2
(en)
|
2014-12-24 |
2022-01-27 |
Genentech, Inc. |
Therapeutic, diagnostic and prognostic methods for cancer of the bladder
|
|
HUE064614T2
(hu)
|
2015-02-25 |
2024-04-28 |
Eisai R&D Man Co Ltd |
Eljárás egy kinolin-származék keserû ízének elnyomására
|
|
CA2978226C
(en)
|
2015-03-04 |
2025-02-18 |
Eisai R&D Management Co., Ltd. |
COMBINATION OF A PD-1 ANTAGONIST AND A VEGFR/FGFR/RET TYROSINE KINASE INHIBITOR TO TREAT CANCER
|
|
MX2017013383A
(es)
|
2015-04-20 |
2017-12-07 |
Tolero Pharmaceuticals Inc |
Prediccion de respuesta a alvocidib mediante perfilado mitocondrial.
|
|
MX382566B
(es)
|
2015-05-01 |
2025-03-13 |
Univ Emory |
Analogos de nucleosidos para el tratamiento de la familia de virus flaviviridae y cancer
|
|
PL3298021T3
(pl)
|
2015-05-18 |
2019-11-29 |
Tolero Pharmaceuticals Inc |
Proleki alvocidibu o zwiększonej biodostępności
|
|
BR112017027227B1
(pt)
|
2015-06-16 |
2023-12-12 |
Eisai R&D Management Co., Ltd |
Agente anti-câncer
|
|
WO2017009751A1
(en)
|
2015-07-15 |
2017-01-19 |
Pfizer Inc. |
Pyrimidine derivatives
|
|
MX2018001289A
(es)
|
2015-08-03 |
2018-04-30 |
Tolero Pharmaceuticals Inc |
Terapias de combinacion para el tratamiento del cancer.
|
|
MX381976B
(es)
|
2015-08-20 |
2025-03-13 |
Eisai R&D Man Co Ltd |
Agente terapéutico contra tumores.
|
|
MX2018006781A
(es)
|
2015-12-03 |
2018-11-09 |
Agios Pharmaceuticals Inc |
Inhibidores de mat2a para el tratamiento del cancer que no expresen mtap.
|
|
WO2018094275A1
(en)
|
2016-11-18 |
2018-05-24 |
Tolero Pharmaceuticals, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
|
WO2018119000A1
(en)
|
2016-12-19 |
2018-06-28 |
Tolero Pharmaceuticals, Inc. |
Profiling peptides and methods for sensitivity profiling
|
|
PL3558955T3
(pl)
|
2016-12-22 |
2021-12-27 |
Amgen Inc. |
Pochodne benzoizotiazolu, izotiazolo[3,4-b]pirydyny, chinazoliny, ftalazyny, pirydo[2,3-d]pirydazyny i pirydo[2,3-d]pirymidyny jako inhibitory kras g12c do leczenia raka płuc, trzustki lub jelita grubego
|
|
KR102539920B1
(ko)
|
2017-02-08 |
2023-06-05 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
종양-치료용 약제학적 조성물
|
|
RU2019134940A
(ru)
|
2017-05-16 |
2021-06-16 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
Лечение гепатоцеллюлярной карциномы
|
|
JOP20190272A1
(ar)
|
2017-05-22 |
2019-11-21 |
Amgen Inc |
مثبطات kras g12c وطرق لاستخدامها
|
|
ES2928576T3
(es)
|
2017-09-08 |
2022-11-21 |
Amgen Inc |
Inhibidores de KRAS G12C y métodos de uso de los mismos
|
|
WO2019055579A1
(en)
|
2017-09-12 |
2019-03-21 |
Tolero Pharmaceuticals, Inc. |
TREATMENT REGIME FOR CANCERS THAT ARE INSENSITIVE TO BCL-2 INHIBITORS USING THE MCL-1 ALVOCIDIB INHIBITOR
|
|
WO2019075367A1
(en)
|
2017-10-13 |
2019-04-18 |
Tolero Pharmaceuticals, Inc. |
PKM2 ACTIVATORS IN COMBINATION WITH OXYGEN REACTIVE SPECIES FOR THE TREATMENT OF CANCER
|
|
CA3099118A1
(en)
|
2018-05-04 |
2019-11-07 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
|
MX2020010836A
(es)
|
2018-05-04 |
2021-01-08 |
Amgen Inc |
Inhibidores de kras g12c y métodos para su uso.
|
|
MA52564A
(fr)
|
2018-05-10 |
2021-03-17 |
Amgen Inc |
Inhibiteurs de kras g12c pour le traitement du cancer
|
|
WO2019232419A1
(en)
|
2018-06-01 |
2019-12-05 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
|
EP4268898A3
(en)
|
2018-06-11 |
2024-01-17 |
Amgen Inc. |
Kras g12c inhibitors for treating cancer
|
|
MA51848A
(fr)
|
2018-06-12 |
2021-04-21 |
Amgen Inc |
Inhibiteurs de kras g12c et leurs procédés d'utilisation
|
|
EP3826684A4
(en)
|
2018-07-26 |
2022-04-06 |
Sumitomo Dainippon Pharma Oncology, Inc. |
METHODS OF TREATMENT OF DISEASES ASSOCIATED WITH ABNORMAL ACVR1 EXPRESSION AND ACVR1 INHIBITORS FOR USE IN THE SAME
|
|
EP3853234B1
(en)
|
2018-09-18 |
2025-04-23 |
Nikang Therapeutics, Inc. |
Fused tricyclic ring derivatives as src homology-2 phosphatase inhibitors
|
|
CN113194954A
(zh)
|
2018-10-04 |
2021-07-30 |
国家医疗保健研究所 |
用于治疗角皮病的egfr抑制剂
|
|
JP7516029B2
(ja)
|
2018-11-16 |
2024-07-16 |
アムジエン・インコーポレーテツド |
Ｋｒａｓ ｇ１２ｃ阻害剤化合物の重要な中間体の改良合成法
|
|
JP7377679B2
(ja)
|
2018-11-19 |
2023-11-10 |
アムジエン・インコーポレーテツド |
がん治療のためのｋｒａｓｇ１２ｃ阻害剤及び１種以上の薬学的に活性な追加の薬剤を含む併用療法
|
|
CA3117222A1
(en)
|
2018-11-19 |
2020-05-28 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
|
AU2019391097B2
(en)
|
2018-12-04 |
2025-07-03 |
Sumitomo Pharma America, Inc. |
CDK9 inhibitors and polymorphs thereof for use as agents for treatment of cancer
|
|
US12441736B2
(en)
|
2018-12-20 |
2025-10-14 |
Amgen Inc. |
KIF18A inhibitors
|
|
IL283639B2
(en)
|
2018-12-20 |
2024-06-01 |
Amgen Inc |
Kif18a inhibitors
|
|
CA3123042A1
(en)
|
2018-12-20 |
2020-06-25 |
Amgen Inc. |
Kif18a inhibitors
|
|
JP2022513967A
(ja)
|
2018-12-20 |
2022-02-09 |
アムジエン・インコーポレーテツド |
Ｋｉｆ１８ａ阻害剤として有用なヘテロアリールアミド
|
|
NL2022471B1
(en)
|
2019-01-29 |
2020-08-18 |
Vationpharma B V |
Solid state forms of oclacitinib
|
|
JP7662528B2
(ja)
|
2019-02-12 |
2025-04-15 |
スミトモ ファーマ アメリカ， インコーポレイテッド |
複素環式タンパク質キナーゼ阻害剤を含む製剤
|
|
US20230148450A9
(en)
|
2019-03-01 |
2023-05-11 |
Revolution Medicines, Inc. |
Bicyclic heteroaryl compounds and uses thereof
|
|
AU2020232616A1
(en)
|
2019-03-01 |
2021-09-09 |
Revolution Medicines, Inc. |
Bicyclic heterocyclyl compounds and uses thereof
|
|
WO2020191326A1
(en)
|
2019-03-20 |
2020-09-24 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Treatment of acute myeloid leukemia (aml) with venetoclax failure
|
|
AU2020245437A1
(en)
|
2019-03-22 |
2021-09-30 |
Sumitomo Pharma Oncology, Inc. |
Compositions comprising PKM2 modulators and methods of treatment using the same
|
|
EP3738593A1
(en)
|
2019-05-14 |
2020-11-18 |
Amgen, Inc |
Dosing of kras inhibitor for treatment of cancers
|
|
NZ782284A
(en)
|
2019-05-21 |
2024-11-29 |
Amgen Inc |
Solid state forms
|
|
CN114269731A
(zh)
|
2019-08-02 |
2022-04-01 |
美国安进公司 |
Kif18a抑制剂
|
|
JP7756070B2
(ja)
|
2019-08-02 |
2025-10-17 |
アムジエン・インコーポレーテツド |
Ｋｉｆ１８ａ阻害剤としてのピリジン誘導体
|
|
WO2021026098A1
(en)
|
2019-08-02 |
2021-02-11 |
Amgen Inc. |
Kif18a inhibitors
|
|
JP7699100B2
(ja)
|
2019-08-02 |
2025-06-26 |
アムジエン・インコーポレーテツド |
Ｋｉｆ１８ａ阻害剤
|
|
MX2022004656A
(es)
|
2019-10-24 |
2022-05-25 |
Amgen Inc |
Derivados de piridopirimidina utiles como inhibidores de kras g12c y kras g12d en el tratamiento del cancer.
|
|
KR20220109406A
(ko)
|
2019-11-04 |
2022-08-04 |
레볼루션 메디슨즈, 인크. |
Ras 억제제
|
|
EP4055028A1
(en)
|
2019-11-04 |
2022-09-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
CA3159561A1
(en)
|
2019-11-04 |
2021-05-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
EP4620531A3
(en)
|
2019-11-08 |
2025-11-26 |
Revolution Medicines, Inc. |
Bicyclic heteroaryl compounds and uses thereof
|
|
AR120457A1
(es)
|
2019-11-14 |
2022-02-16 |
Amgen Inc |
Síntesis mejorada del compuesto inhibidor de g12c de kras
|
|
JP2023501522A
(ja)
|
2019-11-14 |
2023-01-18 |
アムジエン・インコーポレーテツド |
Ｋｒａｓ ｇ１２ｃ阻害剤化合物の改良合成法
|
|
WO2021108683A1
(en)
|
2019-11-27 |
2021-06-03 |
Revolution Medicines, Inc. |
Covalent ras inhibitors and uses thereof
|
|
TW202140011A
(zh)
|
2020-01-07 |
2021-11-01 |
美商銳新醫藥公司 |
Shp2抑制劑給藥和治療癌症的方法
|
|
WO2021155006A1
(en)
|
2020-01-31 |
2021-08-05 |
Les Laboratoires Servier Sas |
Inhibitors of cyclin-dependent kinases and uses thereof
|
|
AU2021293228A1
(en)
|
2020-06-18 |
2023-02-09 |
Revolution Medicines, Inc. |
Methods for delaying, preventing, and treating acquired resistance to RAS inhibitors
|
|
US20250195521A1
(en)
|
2020-09-03 |
2025-06-19 |
Revolution Medicines, Inc. |
Use of sos1 inhibitors to treat malignancies with shp2 mutations
|
|
IL301298A
(en)
|
2020-09-15 |
2023-05-01 |
Revolution Medicines Inc |
Indole derivatives as RAS inhibitors in cancer therapy
|
|
JP2024501280A
(ja)
|
2020-12-22 |
2024-01-11 |
キル・レガー・セラピューティクス・インコーポレーテッド |
Ｓｏｓ１阻害剤およびその使用
|
|
MX2023012060A
(es)
|
2021-04-13 |
2024-01-22 |
Nuvalent Inc |
Heterociclos con sustitucion amino para tratar canceres con mutaciones de egfr.
|
|
TW202309052A
(zh)
|
2021-05-05 |
2023-03-01 |
美商銳新醫藥公司 |
Ｒａｓ抑制劑
|
|
WO2022235870A1
(en)
|
2021-05-05 |
2022-11-10 |
Revolution Medicines, Inc. |
Ras inhibitors for the treatment of cancer
|
|
EP4334324A1
(en)
|
2021-05-05 |
2024-03-13 |
Revolution Medicines, Inc. |
Covalent ras inhibitors and uses thereof
|
|
AR127308A1
(es)
|
2021-10-08 |
2024-01-10 |
Revolution Medicines Inc |
Inhibidores ras
|
|
TW202340214A
(zh)
|
2021-12-17 |
2023-10-16 |
美商健臻公司 |
做為shp2抑制劑之吡唑并吡𠯤化合物
|
|
EP4227307A1
(en)
|
2022-02-11 |
2023-08-16 |
Genzyme Corporation |
Pyrazolopyrazine compounds as shp2 inhibitors
|
|
JP2025509217A
(ja)
|
2022-03-07 |
2025-04-11 |
アムジエン・インコーポレーテツド |
４－メチル－２－プロパン－２－イル－ピリジン－３－カルボニトリルを調製するための方法
|
|
WO2023172940A1
(en)
|
2022-03-08 |
2023-09-14 |
Revolution Medicines, Inc. |
Methods for treating immune refractory lung cancer
|
|
KR20250022133A
(ko)
|
2022-06-10 |
2025-02-14 |
레볼루션 메디슨즈, 인크. |
거대고리 ras 억제제
|
|
AU2023358792A1
(en)
|
2022-10-14 |
2025-04-17 |
Black Diamond Therapeutics, Inc. |
Methods of treating cancers using isoquinoline or 6-aza-quinoline derivatives
|
|
KR20250164828A
(ko)
|
2023-03-30 |
2025-11-25 |
레볼루션 메디슨즈, 인크. |
Ras gtp 가수분해 유도를 위한 조성물 및 이의 용도
|
|
AU2024243852A1
(en)
|
2023-04-07 |
2025-11-06 |
Revolution Medicines, Inc. |
Macrocyclic ras inhibitors
|
|
WO2024211663A1
(en)
|
2023-04-07 |
2024-10-10 |
Revolution Medicines, Inc. |
Condensed macrocyclic compounds as ras inhibitors
|
|
KR20250169290A
(ko)
|
2023-04-14 |
2025-12-02 |
레볼루션 메디슨즈, 인크. |
Ras 억제제의 결정형, 이를 함유하는 조성물 및 이의 사용 방법
|
|
KR20250172857A
(ko)
|
2023-04-14 |
2025-12-09 |
레볼루션 메디슨즈, 인크. |
Ras 억제제의 결정형
|
|
AU2024265078A1
(en)
|
2023-05-04 |
2025-12-11 |
Revolution Medicines, Inc. |
Combination therapy for a ras related disease or disorder
|
|
WO2025034702A1
(en)
|
2023-08-07 |
2025-02-13 |
Revolution Medicines, Inc. |
Rmc-6291 for use in the treatment of ras protein-related disease or disorder
|
|
WO2025080946A2
(en)
|
2023-10-12 |
2025-04-17 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025137507A1
(en)
|
2023-12-22 |
2025-06-26 |
Regor Pharmaceuticals, Inc. |
Sos1 inhibitors and uses thereof
|
|
WO2025171296A1
(en)
|
2024-02-09 |
2025-08-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025240847A1
(en)
|
2024-05-17 |
2025-11-20 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025255438A1
(en)
|
2024-06-07 |
2025-12-11 |
Revolution Medicines, Inc. |
Methods of treating a ras protein-related disease or disorder
|