IN2014CN03557A - - Google Patents

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Publication number
IN2014CN03557A
IN2014CN03557A IN3557CHN2014A IN2014CN03557A IN 2014CN03557 A IN2014CN03557 A IN 2014CN03557A IN 3557CHN2014 A IN3557CHN2014 A IN 3557CHN2014A IN 2014CN03557 A IN2014CN03557 A IN 2014CN03557A
Authority
IN
India
Prior art keywords
compound
mogroside
amogroside
mogrol
diphospho
Prior art date
Application number
Other languages
English (en)
Inventor
Yaoquan Liu
Jung Yeop Lee
Monika Khare
Original Assignee
Evolva Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evolva Sa filed Critical Evolva Sa
Publication of IN2014CN03557A publication Critical patent/IN2014CN03557A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • C12P33/20Preparation of steroids containing heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/18Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
IN3557CHN2014 2011-11-23 2012-11-19 IN2014CN03557A (enExample)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161563303P 2011-11-23 2011-11-23
PCT/IB2012/002857 WO2013076577A1 (en) 2011-11-23 2012-11-19 Methods and materials for enzymatic synthesis of mogroside compounds

Publications (1)

Publication Number Publication Date
IN2014CN03557A true IN2014CN03557A (enExample) 2015-10-09

Family

ID=47624376

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3557CHN2014 IN2014CN03557A (enExample) 2011-11-23 2012-11-19

Country Status (14)

Country Link
US (2) US9920349B2 (enExample)
EP (1) EP2783009B1 (enExample)
JP (1) JP6084983B2 (enExample)
KR (1) KR101791597B1 (enExample)
CN (1) CN103958693B (enExample)
AU (2) AU2012342114B2 (enExample)
BR (1) BR112014012543A2 (enExample)
CA (1) CA2853677C (enExample)
IN (1) IN2014CN03557A (enExample)
MX (1) MX342851B (enExample)
MY (1) MY170686A (enExample)
RU (1) RU2633644C2 (enExample)
SG (1) SG11201401927PA (enExample)
WO (1) WO2013076577A1 (enExample)

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EP2575432B1 (en) 2010-06-02 2019-08-14 Evolva, Inc. Recombinant production of steviol glycosides
AU2012294452C1 (en) 2011-08-08 2017-11-30 Danstar Ferment Ag Recombinant production of steviol glycosides
MY170686A (en) 2011-11-23 2019-08-26 Evolva Sa Methods and meterials for enzymatic synthesis of mogroside compounds
TW201402599A (zh) * 2012-05-30 2014-01-16 Suntory Holdings Ltd 甜菊糖苷糖苷轉化酵素及編碼該酵素之基因
CA2893462A1 (en) 2012-12-04 2014-06-12 Evolva Sa Methods and materials for biosynthesis of mogroside compounds
BR112015019160A2 (pt) 2013-02-11 2017-08-22 Dalgaard Mikkelsen Michael Produção de glicosídeos de esteviol em hospedeiros recombinantes
CN114410493A (zh) 2014-08-11 2022-04-29 埃沃尔瓦公司 在重组宿主中生产甜菊醇糖苷
KR20170052647A (ko) 2014-09-09 2017-05-12 에볼바 에스아 재조합 숙주에서 스테비올 글리코시드의 생성
EP3191584A4 (en) 2014-09-11 2018-07-18 The State of Israel - Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) Methods of producing mogrosides and compositions comprising same and uses thereof
CN107466320B (zh) 2014-10-01 2021-11-05 埃沃尔瓦公司 用于生物合成罗汉果苷化合物的方法和材料
CA2968331C (en) * 2014-10-17 2024-02-06 Suntory Holdings Limited Mogrol glycosyltransferase and gene encoding same
US10626430B2 (en) 2015-01-20 2020-04-21 Suntory Holdings Limited Method for preparing mogroside having no β-1,6-glucoside bond
AU2016211124B2 (en) 2015-01-30 2022-04-14 Danstar Ferment Ag Production of steviol glycosides in recombinant hosts
EP3271457B1 (en) 2015-03-16 2021-01-20 DSM IP Assets B.V. Udp-glycosyltransferases
EP3332018B1 (en) 2015-08-07 2022-07-27 Evolva SA Production of steviol glycosides in recombinant hosts
CA3003163A1 (en) 2015-10-29 2017-05-04 Senomyx, Inc. High intensity sweeteners
CN106924274B (zh) * 2015-12-29 2019-01-04 成都普睿法药物研发有限公司 葫芦烷型四环三萜类化合物抗肺纤维化应用
KR20180132696A (ko) 2016-04-13 2018-12-12 에볼바 에스아 재조합 숙주에서의 스테비올 글리코사이드의 생산
US10815514B2 (en) 2016-05-16 2020-10-27 Evolva Sa Production of steviol glycosides in recombinant hosts
CN109477128A (zh) * 2016-05-16 2019-03-15 埃沃尔瓦公司 在重组宿主中甜菊醇糖苷的生产
JP6845244B2 (ja) * 2016-07-19 2021-03-17 サントリーホールディングス株式会社 モグロールまたはモグロール配糖体の生産方法
WO2018083338A1 (en) 2016-11-07 2018-05-11 Evolva Sa Production of steviol glycosides in recombinant hosts
BR112019023104A2 (pt) 2017-05-03 2020-11-03 Firmenich Incorporated métodos para fazer adoçante de alta intensidade
EP3624595A4 (en) 2017-05-19 2021-03-03 The Coca-Cola Company COMPOSITIONS SWEETED WITH SIAMENOSIDE I AND USES THEREOF
RU2762719C2 (ru) 2017-06-02 2021-12-22 Живодан Са Композиция, модифицирующая сладость
WO2018229283A1 (en) 2017-06-15 2018-12-20 Evolva Sa Production of mogroside compounds in recombinant hosts
CN107189976B (zh) * 2017-07-28 2022-03-11 李华政 促进罗汉果ugt72b21基因表达的方法
US12338476B2 (en) 2018-11-07 2025-06-24 Firmenich Incorporated Methods for making high intensity sweeteners
MX2021005219A (es) 2018-11-07 2021-06-18 Firmenich Incorporated Metodos para hacer edulcorantes de alta intensidad.
EP3877519B1 (en) 2018-11-09 2026-03-11 Ginkgo Bioworks, Inc. Biosynthesis of mogrosides
CN110669094B (zh) * 2019-10-14 2021-12-21 上海交通大学 罗汉果新苷及其制备方法
KR102362135B1 (ko) * 2019-10-25 2022-02-14 고려대학교 산학협력단 테르펜 당쇄 부가 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 조성물
EP4120823A4 (en) * 2020-03-17 2024-08-07 The Coca-Cola Company NOVEL MOGROSID PRODUCTION SYSTEM AND PROCESS
CA3179775A1 (en) 2020-04-20 2021-10-28 Givaudan Sa Compositions
GB202007984D0 (en) 2020-05-28 2020-07-15 Givaudan Sa Compositions
CN112063647B (zh) * 2020-09-17 2023-05-02 云南农业大学 酿酒酵母重组菌Cuol01的构建方法、酿酒酵母重组菌Cuol02及应用
CN116064712B (zh) * 2022-10-08 2025-05-06 中国药科大学 一种罗汉果醇的生物合成方法
CN121127603A (zh) 2023-04-20 2025-12-12 帝斯曼知识产权资产管理有限公司 用于产生罗汉果苷的菌株和方法

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US6399321B1 (en) * 1999-08-18 2002-06-04 National Research Council Of Canada Methods for screening UDP-glucose:glycoprotein glucosyltransferase (UGGT) activity and nucleic acid encoding for UGGT
EP1510573A1 (en) * 2003-09-01 2005-03-02 Austria Wirtschaftsservice Gesellschaft mit beschränkter Haftung Method for detoxification of mycotoxins
US20080148432A1 (en) * 2005-12-21 2008-06-19 Mark Scott Abad Transgenic plants with enhanced agronomic traits
WO2006092449A2 (en) 2005-03-02 2006-09-08 Metanomics Gmbh Process for the production of fine chemicals
US8257948B1 (en) * 2011-02-17 2012-09-04 Purecircle Usa Method of preparing alpha-glucosyl Stevia composition
US8956677B2 (en) 2005-11-23 2015-02-17 The Coca-Cola Company High-potency sweetener composition with glucosamine and compositions sweetened therewith
RU2008122901A (ru) * 2005-11-23 2009-12-27 Дзе Кока-Кола Компани (US) Композиция интенсивного подсластителя с сапонином и подслащенные ею композиции
US7927851B2 (en) 2006-03-21 2011-04-19 Vineland Research And Innovation Centre Compositions having ent-kaurenoic acid 13-hydroxylase activity and methods for producing same
US20100143975A1 (en) * 2006-11-22 2010-06-10 The University Of York Monoterpenoid modifying enzymes
WO2008065370A2 (en) * 2006-12-01 2008-06-05 The University Of York Sesquiterpenoid modifying enzymes
GB0904639D0 (en) 2009-03-18 2009-04-29 Univ York Assay
EP2575432B1 (en) 2010-06-02 2019-08-14 Evolva, Inc. Recombinant production of steviol glycosides
MY170686A (en) 2011-11-23 2019-08-26 Evolva Sa Methods and meterials for enzymatic synthesis of mogroside compounds
CA2893462A1 (en) 2012-12-04 2014-06-12 Evolva Sa Methods and materials for biosynthesis of mogroside compounds

Also Published As

Publication number Publication date
CA2853677C (en) 2019-01-29
AU2012342114B2 (en) 2017-12-21
RU2014125216A (ru) 2015-12-27
US20140308698A1 (en) 2014-10-16
EP2783009B1 (en) 2016-04-13
US20180237819A1 (en) 2018-08-23
JP2014533518A (ja) 2014-12-15
MY170686A (en) 2019-08-26
AU2012342114A1 (en) 2014-05-22
AU2017235907A1 (en) 2017-10-12
KR101791597B1 (ko) 2017-10-30
US10738340B2 (en) 2020-08-11
BR112014012543A2 (pt) 2017-06-13
CN103958693A (zh) 2014-07-30
KR20140099281A (ko) 2014-08-11
EP2783009A1 (en) 2014-10-01
CN103958693B (zh) 2016-08-24
WO2013076577A1 (en) 2013-05-30
HK1200494A1 (zh) 2015-08-07
CA2853677A1 (en) 2013-05-30
JP6084983B2 (ja) 2017-02-22
RU2633644C2 (ru) 2017-10-16
MX2014006276A (es) 2014-10-13
US9920349B2 (en) 2018-03-20
MX342851B (es) 2016-10-14
SG11201401927PA (en) 2014-09-26

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