IN2014CN03557A - - Google Patents

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Publication number
IN2014CN03557A
IN2014CN03557A IN3557CHN2014A IN2014CN03557A IN 2014CN03557 A IN2014CN03557 A IN 2014CN03557A IN 3557CHN2014 A IN3557CHN2014 A IN 3557CHN2014A IN 2014CN03557 A IN2014CN03557 A IN 2014CN03557A
Authority
IN
India
Prior art keywords
compound
mogroside
amogroside
mogrol
diphospho
Prior art date
Application number
Other languages
English (en)
Inventor
Yaoquan Liu
Jung Yeop Lee
Monika Khare
Original Assignee
Evolva Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evolva Sa filed Critical Evolva Sa
Publication of IN2014CN03557A publication Critical patent/IN2014CN03557A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • C12P33/20Preparation of steroids containing heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/18Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
IN3557CHN2014 2011-11-23 2012-11-19 IN2014CN03557A (enExample)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161563303P 2011-11-23 2011-11-23
PCT/IB2012/002857 WO2013076577A1 (en) 2011-11-23 2012-11-19 Methods and materials for enzymatic synthesis of mogroside compounds

Publications (1)

Publication Number Publication Date
IN2014CN03557A true IN2014CN03557A (enExample) 2015-10-09

Family

ID=47624376

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3557CHN2014 IN2014CN03557A (enExample) 2011-11-23 2012-11-19

Country Status (14)

Country Link
US (2) US9920349B2 (enExample)
EP (1) EP2783009B1 (enExample)
JP (1) JP6084983B2 (enExample)
KR (1) KR101791597B1 (enExample)
CN (1) CN103958693B (enExample)
AU (2) AU2012342114B2 (enExample)
BR (1) BR112014012543A2 (enExample)
CA (1) CA2853677C (enExample)
IN (1) IN2014CN03557A (enExample)
MX (1) MX342851B (enExample)
MY (1) MY170686A (enExample)
RU (1) RU2633644C2 (enExample)
SG (1) SG11201401927PA (enExample)
WO (1) WO2013076577A1 (enExample)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6177127B2 (ja) 2010-06-02 2017-08-09 エボルバ, インク.Evolva, Inc. ステビオールグリコシドの組換え生成
SG10201606567TA (en) 2011-08-08 2016-10-28 Evolva Sa Recombinant production of steviol glycosides
RU2633644C2 (ru) 2011-11-23 2017-10-16 Эвольва Са Способы ферментативного синтеза могрозидных соединений
TW201402599A (zh) * 2012-05-30 2014-01-16 Suntory Holdings Ltd 甜菊糖苷糖苷轉化酵素及編碼該酵素之基因
SG10201704575XA (en) 2012-12-04 2017-07-28 Evolva Sa Methods and materials for biosynthesis of mogroside compounds
US10017804B2 (en) 2013-02-11 2018-07-10 Evolva Sa Efficient production of steviol glycosides in recombinant hosts
EP3179869A1 (en) 2014-08-11 2017-06-21 Evolva SA Production of steviol glycosides in recombinant hosts
BR112017004712B1 (pt) 2014-09-09 2021-11-03 Evolva Sa Hospedeiro recombinante que produz um precursor de glicosídeo de esteviol, métodos para produzir um precursor de glicosídeo de esteviol, um esteviol ou um ou mais glicosídeos de esteviol, cultura do dito hospedeiro e lisado da cultura do dito hospedeiro
US20170283844A1 (en) 2014-09-11 2017-10-05 The State of Israel, Ministry of Agriculture & Rural Development, Argricultural Research Organiza Methods of producing mogrosides and compositions comprising same and uses thereof
EP3201315A2 (en) 2014-10-01 2017-08-09 Evolva SA Methods and materials for biosynthesis of mogroside compounds
EP3208342A4 (en) 2014-10-17 2018-07-04 Suntory Holdings Limited Mogrol glycosyltransferase and gene encoding same
US10626430B2 (en) 2015-01-20 2020-04-21 Suntory Holdings Limited Method for preparing mogroside having no β-1,6-glucoside bond
BR112017016338A2 (pt) 2015-01-30 2018-03-27 Evolva Sa produção de glicosídeos de esteviol em hospedeiros recombinantes
CN107567492B (zh) 2015-03-16 2022-10-14 帝斯曼知识产权资产管理有限公司 Udp-糖基转移酶
WO2017025362A1 (en) 2015-08-07 2017-02-16 Evolva Sa Production of steviol glycosides in recombinant hosts
ES2925017T3 (es) 2015-10-29 2022-10-13 Firmenich Incorporated Edulcorantes de alta intensidad
CN106924274B (zh) * 2015-12-29 2019-01-04 成都普睿法药物研发有限公司 葫芦烷型四环三萜类化合物抗肺纤维化应用
MY198001A (en) 2016-04-13 2023-07-25 Evolva SA Production of steviol glycoside in recombinant hosts
US10815514B2 (en) 2016-05-16 2020-10-27 Evolva Sa Production of steviol glycosides in recombinant hosts
BR112018073662A2 (pt) * 2016-05-16 2019-02-19 Evolva Sa produção de glicosídeos de esteviol em hospedeiros recombinantes
CN109477126B (zh) 2016-07-19 2023-06-20 三得利控股株式会社 罗汉果醇或罗汉果醇糖苷的生产方法
EP3535406A1 (en) 2016-11-07 2019-09-11 Evolva SA Production of steviol glycosides in recombinant hosts
US11060124B2 (en) * 2017-05-03 2021-07-13 Firmenich Incorporated Methods for making high intensity sweeteners
CN111246749A (zh) 2017-05-19 2020-06-05 可口可乐公司 翅子罗汉果i甜味化的组合物及其用途
CN116941752A (zh) 2017-06-02 2023-10-27 奇华顿股份有限公司 组合物
WO2018229283A1 (en) 2017-06-15 2018-12-20 Evolva Sa Production of mogroside compounds in recombinant hosts
CN107189976B (zh) * 2017-07-28 2022-03-11 李华政 促进罗汉果ugt72b21基因表达的方法
CA3118467A1 (en) 2018-11-07 2020-05-14 Firmenich Incorporated Methods for making high intensity sweeteners
JP2022512931A (ja) 2018-11-07 2022-02-07 フィルメニッヒ インコーポレイテッド 高甘味度甘味料の製造方法
CN113302298B (zh) 2018-11-09 2025-02-25 银杏生物制品公司 罗汉果甙的生物合成
CN110669094B (zh) * 2019-10-14 2021-12-21 上海交通大学 罗汉果新苷及其制备方法
KR102362135B1 (ko) * 2019-10-25 2022-02-14 고려대학교 산학협력단 테르펜 당쇄 부가 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 조성물
WO2021188703A1 (en) * 2020-03-17 2021-09-23 The Coca-Cola Company Novel mogroside production system and methods
EP4138574A1 (en) 2020-04-20 2023-03-01 Givaudan SA Compositions
GB202007984D0 (en) 2020-05-28 2020-07-15 Givaudan Sa Compositions
CN112063647B (zh) * 2020-09-17 2023-05-02 云南农业大学 酿酒酵母重组菌Cuol01的构建方法、酿酒酵母重组菌Cuol02及应用
CN116064712B (zh) * 2022-10-08 2025-05-06 中国药科大学 一种罗汉果醇的生物合成方法
WO2024218244A1 (en) 2023-04-20 2024-10-24 Dsm Ip Assets B.V. Strains and methods for the production of mogrosides

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6399321B1 (en) * 1999-08-18 2002-06-04 National Research Council Of Canada Methods for screening UDP-glucose:glycoprotein glucosyltransferase (UGGT) activity and nucleic acid encoding for UGGT
EP1510573A1 (en) * 2003-09-01 2005-03-02 Austria Wirtschaftsservice Gesellschaft mit beschränkter Haftung Method for detoxification of mycotoxins
US20080148432A1 (en) * 2005-12-21 2008-06-19 Mark Scott Abad Transgenic plants with enhanced agronomic traits
EP2194140A2 (en) 2005-03-02 2010-06-09 Metanomics GmbH Process for the production of fine chemicals
US8257948B1 (en) * 2011-02-17 2012-09-04 Purecircle Usa Method of preparing alpha-glucosyl Stevia composition
US8956677B2 (en) 2005-11-23 2015-02-17 The Coca-Cola Company High-potency sweetener composition with glucosamine and compositions sweetened therewith
RU2008123259A (ru) * 2005-11-23 2009-12-27 Дзе Кока-Кола Компани (US) Композиция интенсивного подсластителя с противовоспалительным средством и подслащенные ею композиции
US7927851B2 (en) 2006-03-21 2011-04-19 Vineland Research And Innovation Centre Compositions having ent-kaurenoic acid 13-hydroxylase activity and methods for producing same
WO2008062165A2 (en) * 2006-11-22 2008-05-29 The University Of York Monoterpenoid modifying enzymes
WO2008065370A2 (en) * 2006-12-01 2008-06-05 The University Of York Sesquiterpenoid modifying enzymes
GB0904639D0 (en) * 2009-03-18 2009-04-29 Univ York Assay
JP6177127B2 (ja) 2010-06-02 2017-08-09 エボルバ, インク.Evolva, Inc. ステビオールグリコシドの組換え生成
RU2633644C2 (ru) 2011-11-23 2017-10-16 Эвольва Са Способы ферментативного синтеза могрозидных соединений
SG10201704575XA (en) 2012-12-04 2017-07-28 Evolva Sa Methods and materials for biosynthesis of mogroside compounds

Also Published As

Publication number Publication date
MX2014006276A (es) 2014-10-13
AU2017235907A1 (en) 2017-10-12
KR101791597B1 (ko) 2017-10-30
EP2783009A1 (en) 2014-10-01
HK1200494A1 (zh) 2015-08-07
RU2633644C2 (ru) 2017-10-16
US10738340B2 (en) 2020-08-11
BR112014012543A2 (pt) 2017-06-13
AU2012342114A1 (en) 2014-05-22
JP2014533518A (ja) 2014-12-15
JP6084983B2 (ja) 2017-02-22
US20140308698A1 (en) 2014-10-16
CA2853677C (en) 2019-01-29
WO2013076577A1 (en) 2013-05-30
RU2014125216A (ru) 2015-12-27
KR20140099281A (ko) 2014-08-11
SG11201401927PA (en) 2014-09-26
CA2853677A1 (en) 2013-05-30
MX342851B (es) 2016-10-14
US9920349B2 (en) 2018-03-20
EP2783009B1 (en) 2016-04-13
CN103958693B (zh) 2016-08-24
CN103958693A (zh) 2014-07-30
US20180237819A1 (en) 2018-08-23
MY170686A (en) 2019-08-26
AU2012342114B2 (en) 2017-12-21

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