MX357509B - Sintesis de cleistantina a y derivados de la misma. - Google Patents

Sintesis de cleistantina a y derivados de la misma.

Info

Publication number
MX357509B
MX357509B MX2014000232A MX2014000232A MX357509B MX 357509 B MX357509 B MX 357509B MX 2014000232 A MX2014000232 A MX 2014000232A MX 2014000232 A MX2014000232 A MX 2014000232A MX 357509 B MX357509 B MX 357509B
Authority
MX
Mexico
Prior art keywords
synthesis
derivatives
cleistanthin
provides
diphyllin
Prior art date
Application number
MX2014000232A
Other languages
English (en)
Other versions
MX2014000232A (es
Inventor
Mulik Nilesh Shridhar
Panghavane Kailash Datatraya
Original Assignee
Godavari Biorefineries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Godavari Biorefineries Ltd filed Critical Godavari Biorefineries Ltd
Publication of MX2014000232A publication Critical patent/MX2014000232A/es
Publication of MX357509B publication Critical patent/MX357509B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/54—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención provee un método para preparar Cleistantina A, un glucósido de difilina, derivados de la misma e intermediarios para la misma. En particular la presente invención provee en uno de los aspectos un método para la síntesis de un compuesto de la fórmula D, un intermediario clave de difilina, el cual se puede llevar a cabo en una duración más corta y a una temperatura ordinaria.
MX2014000232A 2011-06-30 2012-06-29 Sintesis de cleistantina a y derivados de la misma. MX357509B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161503136P 2011-06-30 2011-06-30
PCT/IB2012/001296 WO2013001352A2 (en) 2011-06-30 2012-06-29 Synthesis of cleistanthin a an derivatives thereof

Publications (2)

Publication Number Publication Date
MX2014000232A MX2014000232A (es) 2014-10-17
MX357509B true MX357509B (es) 2018-07-12

Family

ID=47424602

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014000232A MX357509B (es) 2011-06-30 2012-06-29 Sintesis de cleistantina a y derivados de la misma.

Country Status (11)

Country Link
US (1) US8957230B2 (es)
EP (1) EP2726458B1 (es)
JP (1) JP6010118B2 (es)
AU (1) AU2012277481B2 (es)
BR (1) BR112013033755A2 (es)
CA (1) CA2840473C (es)
IL (1) IL230183A (es)
IN (1) IN2014MN00174A (es)
MX (1) MX357509B (es)
WO (1) WO2013001352A2 (es)
ZA (1) ZA201400248B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150328245A1 (en) * 2012-12-18 2015-11-19 Godavari Biorefineries Limited Agents for Eliminating Tumour-Initiating Cells
KR101492961B1 (ko) 2013-01-31 2015-02-13 한국과학기술연구원 아릴 나프탈렌 리그난 구조의 저스티시딘a 유도체 및 그의 제조방법
CN104370982B (zh) * 2014-05-19 2017-11-21 南开大学 一类山荷叶素衍生物及其制备方法和用途
JP2016063599A (ja) * 2014-09-17 2016-04-25 ナブテスコ株式会社 減速機付モータ
WO2020129082A1 (en) * 2018-12-17 2020-06-25 Godavari Biorefineries Limited Compounds for the inhibition of unregulated cell growth
CN115867276A (zh) * 2020-05-11 2023-03-28 戈达瓦里生物炼制有限责任公司 化合物用于治疗病毒感染的用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59164741A (ja) * 1983-03-09 1984-09-17 Daikin Ind Ltd β−（フルオロアルキル又はアルケニル）−β−ヒドロキシアルキンの製造方法
US4574153A (en) * 1985-03-01 1986-03-04 E. R. Squibb & Sons, Inc. 8-Oxo-2-oxa-1-azabicyclo(4.2.0)octane-3-carboxylic acids
US5728370A (en) * 1993-04-02 1998-03-17 Nycomed Imaging As Free Radicals
GB9609976D0 (en) * 1996-05-13 1996-07-17 Lilly Industries Ltd Pharmaceutical compounds
GB0022016D0 (en) * 2000-09-08 2000-10-25 Aea Technology Plc Chemical process plant
SE0301202D0 (sv) * 2003-04-24 2003-04-24 Orteca Ab C O Karolinska Innov New use and new compounds
WO2005097767A1 (en) * 2004-03-30 2005-10-20 Merck & Co., Inc. 2-aminothiazole compounds useful as aspartyl protease inhibitors
GB0623012D0 (en) * 2006-11-17 2006-12-27 Nordic Bioscience As Diphyllin and other lignans as a medicament for V-ATPase mediated disease
ES2599002T3 (es) * 2008-05-08 2017-01-31 Nova Southeastern University Inhibidores específicos para receptores del factor de crecimiento endotelial vascular
US20120029179A1 (en) 2009-02-05 2012-02-02 Godavari Biorefineries Ltd. Process for the synthesis of cleistanthin

Also Published As

Publication number Publication date
US20130012727A1 (en) 2013-01-10
EP2726458A4 (en) 2014-12-31
AU2012277481A1 (en) 2014-01-30
EP2726458A2 (en) 2014-05-07
NZ619726A (en) 2016-05-27
WO2013001352A3 (en) 2013-04-11
IL230183A0 (en) 2014-03-06
BR112013033755A2 (pt) 2016-08-16
ZA201400248B (en) 2014-10-29
EP2726458B1 (en) 2017-01-04
IL230183A (en) 2017-08-31
IN2014MN00174A (es) 2015-06-19
WO2013001352A2 (en) 2013-01-03
JP6010118B2 (ja) 2016-10-19
US8957230B2 (en) 2015-02-17
CA2840473A1 (en) 2013-01-03
CA2840473C (en) 2019-04-09
MX2014000232A (es) 2014-10-17
AU2012277481B2 (en) 2016-10-06
JP2015501283A (ja) 2015-01-15

Similar Documents

Publication Publication Date Title
EP2679592A4 (en) NEW HETEROCYCLIC COMPOUND, PROCESS FOR PRODUCING INTERMEDIATE PRODUCTS THEREOF AND USE THEREOF
PT2509958E (pt) Derivados de azol, métodos para produzir os mesmos, seus intermediários, agentes de agro-horticultura
ZA201503125B (en) One-pot method for the synthesis of cu-ssz-13, the compound obtained by the method and use thereof
TN2011000673A1 (en) Bace inhibitors
MX341456B (es) Amino-quinolinas como inhibidores de cinasa.
UA104438C2 (uk) Спосіб одержання дабігатрану і його проміжних сполук
MX2014002770A (es) Nuevos derivados dihidroquinolina-2-ona.
WO2013098833A3 (en) Processes and intermediates for preparing rivaroxaban
IN2014CN04160A (es)
BR112013019520A2 (pt) método para produção de 2,3-butanodiol por fermentação
MX357509B (es) Sintesis de cleistantina a y derivados de la misma.
TN2013000354A1 (en) Synthesis of 2-carboxamide cycloamino urea derivatives
NZ720106A (en) A process for the preparation of regadenoson
MX2012006524A (es) Proceso para la sintesis de compuestos intermedios de utilidad para preparar compuestos sustituidos de indazol y azaindol.
EP2719695A4 (en) AZOLE DERIVATIVE, PROCESS FOR PRODUCING AZOLE DERIVATIVE, AND INTERMEDIATE COMPOUND
IL227590B (en) A method for producing derivatives of 1-h-pyrrolidine-4,2-dione
ZA201301799B (en) Process for the preparation of pan-cdk inhibitors of the formula (i),and intermediates of the preparation
MX2013009388A (es) Nuevos compuestos de azaespirodecanona como inhibidores de lipasa sensible a hormonas (hsl).
MX2013013021A (es) Nuevos compuestos de hexahidropirroloimidazolona.
IN2013MU01219A (es)
GB2511240A (en) Nitrofurfuryl substituted phenyl linked piperidino-oxadiazoline conjugates as anti-tubercular agents and process for the preparation thereof
HRP20180032T8 (hr) Postupak dobivanja spoja 4,4,7-trifluor-1,2,3,4-tetrahidro-5h-1-benzazepina i međuprodukta u njegovoj sintezi
EA201400882A1 (ru) Способ стереоселективного синтеза 9-гидрокси-5-оксо-1,4-диазаспиро[5.5]ундеканов, содержащих защитные группы в 1,4-положениях
MX2011008557A (es) Sintesis quimica mejorada de diazaindoles por ciclizacion de chichibabin.
WO2012100005A3 (en) Synthetic transtaganolide and basiliolide products, derivatives thereof, and synthesis methods thereof

Legal Events

Date Code Title Description
FG Grant or registration