MX344858B - Nuevo procedimiento para la síntesis de rifaximina y una nueva forma pseudocristalina de rifaximina obtenida con el mismo. - Google Patents

Nuevo procedimiento para la síntesis de rifaximina y una nueva forma pseudocristalina de rifaximina obtenida con el mismo.

Info

Publication number
MX344858B
MX344858B MX2013013463A MX2013013463A MX344858B MX 344858 B MX344858 B MX 344858B MX 2013013463 A MX2013013463 A MX 2013013463A MX 2013013463 A MX2013013463 A MX 2013013463A MX 344858 B MX344858 B MX 344858B
Authority
MX
Mexico
Prior art keywords
rifaximin
new
crystalline form
synthesis
pseudo
Prior art date
Application number
MX2013013463A
Other languages
English (en)
Other versions
MX2013013463A (es
Inventor
Disma Mazzola
Silvia Moiana
Germano Coppi
Original Assignee
Friulchem Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Friulchem Spa filed Critical Friulchem Spa
Publication of MX2013013463A publication Critical patent/MX2013013463A/es
Publication of MX344858B publication Critical patent/MX344858B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para la preparación de rifaximina, rifaximina pseudocristalina y nueva forma pseudocristalina de rifaximina con menos impurezas obtenida por medio de la presente.
MX2013013463A 2011-05-19 2012-05-21 Nuevo procedimiento para la síntesis de rifaximina y una nueva forma pseudocristalina de rifaximina obtenida con el mismo. MX344858B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2011/058171 WO2012155981A1 (en) 2011-05-19 2011-05-19 New process for the synthesis of rifaximin and a new pseudo-crystalline form of rifaximin obtained thereby
PCT/EP2012/059404 WO2012156533A1 (en) 2011-05-19 2012-05-21 New process for the synthesis of rifaximin and a new pseudo-crystalline form of rifaximin obtained thereby

Publications (2)

Publication Number Publication Date
MX2013013463A MX2013013463A (es) 2014-05-30
MX344858B true MX344858B (es) 2017-01-09

Family

ID=46085998

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013013463A MX344858B (es) 2011-05-19 2012-05-21 Nuevo procedimiento para la síntesis de rifaximina y una nueva forma pseudocristalina de rifaximina obtenida con el mismo.

Country Status (4)

Country Link
US (1) US9150590B2 (es)
ES (1) ES2634452T3 (es)
MX (1) MX344858B (es)
WO (2) WO2012155981A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1698630T3 (pl) 2005-03-03 2014-12-31 Alfasigma Spa Nowe postacie polimorficzne rifaksyminy,sposoby ich wytwarzania i ich zastosowanie w preparatach leczniczych
ITMI20061692A1 (it) 2006-09-05 2008-03-06 Alfa Wassermann Spa Uso di polioli per ottenere forme polimorfe stabili di rifaximina
US9018684B2 (en) 2009-11-23 2015-04-28 California Institute Of Technology Chemical sensing and/or measuring devices and methods
US9359374B2 (en) 2012-06-13 2016-06-07 Apotex Pharmachem Inc. Polymorphic forms of rifaximin
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
CN105324109A (zh) 2013-04-12 2016-02-10 意大利阿尔法韦士曼制药公司 Nsaid施用和相关的组合物、方法和系统
ES2621557T3 (es) 2014-03-31 2017-07-04 Euticals S.P.A. Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas
EP3546464B1 (en) 2014-05-12 2020-06-17 Alfasigma S.p.A. Preparation and use of crystalline form tau of rifaximin solvated with degme
WO2016204474A2 (ko) * 2015-06-18 2016-12-22 주식회사대성미생물연구소 리팍시민 결정체를 포함하는 동물 장염 치료용 수의학적 조성물
WO2020128583A1 (en) * 2018-12-19 2020-06-25 Friulchem S.P.A. Process for the manufacture of a tablet of rifaximin and tablet of rifaximin

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3417791A1 (de) 1984-05-14 1985-11-14 Basf Ag, 6700 Ludwigshafen Neue halogenvinylbenzylester, deren herstellung und verwendung zur schaedlingsbekaempfung
IT1199374B (it) 1984-05-15 1988-12-30 Alfa Farmaceutici Spa Processo per la preparazione di pirido-imidazo-rifamicine
ITMI20032144A1 (it) 2003-11-07 2005-05-08 Alfa Wassermann Spa Forme polimorfe di rifaximina, processi per ottenerle e
CA2663776C (en) 2006-09-22 2016-01-26 Cipla Limited Rifaximin in an amorphous form
ITMI20071241A1 (it) 2007-06-20 2008-12-21 Solmag S P A Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta
US7709634B2 (en) 2007-09-20 2010-05-04 Apotex Pharmachem Inc. Amorphous form of rifaximin and processes for its preparation
NZ587099A (en) 2008-02-25 2012-08-31 Salix Pharmaceuticals Ltd Forms of rifaximin and uses thereof
CN101585843B (zh) * 2008-05-21 2011-07-06 重庆赛诺生物药业股份有限公司 一种利福昔明的制备工艺

Also Published As

Publication number Publication date
WO2012156533A1 (en) 2012-11-22
US20140155422A1 (en) 2014-06-05
WO2012155981A1 (en) 2012-11-22
MX2013013463A (es) 2014-05-30
ES2634452T3 (es) 2017-09-27
US9150590B2 (en) 2015-10-06

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