MX344858B - Nuevo procedimiento para la síntesis de rifaximina y una nueva forma pseudocristalina de rifaximina obtenida con el mismo. - Google Patents
Nuevo procedimiento para la síntesis de rifaximina y una nueva forma pseudocristalina de rifaximina obtenida con el mismo.Info
- Publication number
- MX344858B MX344858B MX2013013463A MX2013013463A MX344858B MX 344858 B MX344858 B MX 344858B MX 2013013463 A MX2013013463 A MX 2013013463A MX 2013013463 A MX2013013463 A MX 2013013463A MX 344858 B MX344858 B MX 344858B
- Authority
- MX
- Mexico
- Prior art keywords
- rifaximin
- new
- crystalline form
- synthesis
- pseudo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedimiento para la preparación de rifaximina, rifaximina pseudocristalina y nueva forma pseudocristalina de rifaximina con menos impurezas obtenida por medio de la presente.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2011/058171 WO2012155981A1 (en) | 2011-05-19 | 2011-05-19 | New process for the synthesis of rifaximin and a new pseudo-crystalline form of rifaximin obtained thereby |
PCT/EP2012/059404 WO2012156533A1 (en) | 2011-05-19 | 2012-05-21 | New process for the synthesis of rifaximin and a new pseudo-crystalline form of rifaximin obtained thereby |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2013013463A MX2013013463A (es) | 2014-05-30 |
MX344858B true MX344858B (es) | 2017-01-09 |
Family
ID=46085998
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013013463A MX344858B (es) | 2011-05-19 | 2012-05-21 | Nuevo procedimiento para la síntesis de rifaximina y una nueva forma pseudocristalina de rifaximina obtenida con el mismo. |
Country Status (4)
Country | Link |
---|---|
US (1) | US9150590B2 (es) |
ES (1) | ES2634452T3 (es) |
MX (1) | MX344858B (es) |
WO (2) | WO2012155981A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL1698630T3 (pl) | 2005-03-03 | 2014-12-31 | Alfasigma Spa | Nowe postacie polimorficzne rifaksyminy,sposoby ich wytwarzania i ich zastosowanie w preparatach leczniczych |
ITMI20061692A1 (it) | 2006-09-05 | 2008-03-06 | Alfa Wassermann Spa | Uso di polioli per ottenere forme polimorfe stabili di rifaximina |
US9018684B2 (en) | 2009-11-23 | 2015-04-28 | California Institute Of Technology | Chemical sensing and/or measuring devices and methods |
US9359374B2 (en) | 2012-06-13 | 2016-06-07 | Apotex Pharmachem Inc. | Polymorphic forms of rifaximin |
ITBO20120368A1 (it) | 2012-07-06 | 2014-01-07 | Alfa Wassermann Spa | Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso. |
CN105324109A (zh) | 2013-04-12 | 2016-02-10 | 意大利阿尔法韦士曼制药公司 | Nsaid施用和相关的组合物、方法和系统 |
ES2621557T3 (es) | 2014-03-31 | 2017-07-04 | Euticals S.P.A. | Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas |
EP3546464B1 (en) | 2014-05-12 | 2020-06-17 | Alfasigma S.p.A. | Preparation and use of crystalline form tau of rifaximin solvated with degme |
WO2016204474A2 (ko) * | 2015-06-18 | 2016-12-22 | 주식회사대성미생물연구소 | 리팍시민 결정체를 포함하는 동물 장염 치료용 수의학적 조성물 |
WO2020128583A1 (en) * | 2018-12-19 | 2020-06-25 | Friulchem S.P.A. | Process for the manufacture of a tablet of rifaximin and tablet of rifaximin |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3417791A1 (de) | 1984-05-14 | 1985-11-14 | Basf Ag, 6700 Ludwigshafen | Neue halogenvinylbenzylester, deren herstellung und verwendung zur schaedlingsbekaempfung |
IT1199374B (it) | 1984-05-15 | 1988-12-30 | Alfa Farmaceutici Spa | Processo per la preparazione di pirido-imidazo-rifamicine |
ITMI20032144A1 (it) | 2003-11-07 | 2005-05-08 | Alfa Wassermann Spa | Forme polimorfe di rifaximina, processi per ottenerle e |
CA2663776C (en) | 2006-09-22 | 2016-01-26 | Cipla Limited | Rifaximin in an amorphous form |
ITMI20071241A1 (it) | 2007-06-20 | 2008-12-21 | Solmag S P A | Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta |
US7709634B2 (en) | 2007-09-20 | 2010-05-04 | Apotex Pharmachem Inc. | Amorphous form of rifaximin and processes for its preparation |
NZ587099A (en) | 2008-02-25 | 2012-08-31 | Salix Pharmaceuticals Ltd | Forms of rifaximin and uses thereof |
CN101585843B (zh) * | 2008-05-21 | 2011-07-06 | 重庆赛诺生物药业股份有限公司 | 一种利福昔明的制备工艺 |
-
2011
- 2011-05-19 WO PCT/EP2011/058171 patent/WO2012155981A1/en active Application Filing
-
2012
- 2012-05-21 MX MX2013013463A patent/MX344858B/es active IP Right Grant
- 2012-05-21 ES ES12721559.8T patent/ES2634452T3/es active Active
- 2012-05-21 US US14/118,561 patent/US9150590B2/en active Active
- 2012-05-21 WO PCT/EP2012/059404 patent/WO2012156533A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2012156533A1 (en) | 2012-11-22 |
US20140155422A1 (en) | 2014-06-05 |
WO2012155981A1 (en) | 2012-11-22 |
MX2013013463A (es) | 2014-05-30 |
ES2634452T3 (es) | 2017-09-27 |
US9150590B2 (en) | 2015-10-06 |
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