BR112014012543A2 - métodos e materiais para síntese enzimática de compostos de mogrosídeo - Google Patents

métodos e materiais para síntese enzimática de compostos de mogrosídeo

Info

Publication number
BR112014012543A2
BR112014012543A2 BR112014012543A BR112014012543A BR112014012543A2 BR 112014012543 A2 BR112014012543 A2 BR 112014012543A2 BR 112014012543 A BR112014012543 A BR 112014012543A BR 112014012543 A BR112014012543 A BR 112014012543A BR 112014012543 A2 BR112014012543 A2 BR 112014012543A2
Authority
BR
Brazil
Prior art keywords
materials
methods
enzymatic synthesis
mogroside compounds
compounds
Prior art date
Application number
BR112014012543A
Other languages
English (en)
Inventor
Yeop Lee Jung
Khare Monika
Liu Yaoquan
Original Assignee
Evolva Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evolva Sa filed Critical Evolva Sa
Publication of BR112014012543A2 publication Critical patent/BR112014012543A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/20—Preparation of steroids containing heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

resumo “métodos e materiais para síntese enzimática de compostos de mogrosídeo” métodos e materiais para síntese enzimática de compostos de mogrosí-deo descritos.
BR112014012543A 2011-11-23 2012-11-19 métodos e materiais para síntese enzimática de compostos de mogrosídeo BR112014012543A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161563303P 2011-11-23 2011-11-23
PCT/IB2012/002857 WO2013076577A1 (en) 2011-11-23 2012-11-19 Methods and materials for enzymatic synthesis of mogroside compounds

Publications (1)

Publication Number Publication Date
BR112014012543A2 true BR112014012543A2 (pt) 2017-06-13

Family

ID=47624376

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014012543A BR112014012543A2 (pt) 2011-11-23 2012-11-19 métodos e materiais para síntese enzimática de compostos de mogrosídeo

Country Status (15)

Country Link
US (2) US9920349B2 (pt)
EP (1) EP2783009B1 (pt)
JP (1) JP6084983B2 (pt)
KR (1) KR101791597B1 (pt)
CN (1) CN103958693B (pt)
AU (2) AU2012342114B2 (pt)
BR (1) BR112014012543A2 (pt)
CA (1) CA2853677C (pt)
HK (1) HK1200494A1 (pt)
IN (1) IN2014CN03557A (pt)
MX (1) MX342851B (pt)
MY (1) MY170686A (pt)
RU (1) RU2633644C2 (pt)
SG (1) SG11201401927PA (pt)
WO (1) WO2013076577A1 (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112012030836B8 (pt) 2010-06-02 2024-02-06 Evolva Nutrition Inc Hospedeiro recombinante que compreende genes recombinantes para produção de esteviol ou glicosídeo de esteviol, método para produzir esteviol, glicosídeo de esteviol ou composição de glicosídeo de esteviol e método para sintetizar esteviol ou glicosídeo de esteviol
BR122021015509B1 (pt) 2011-08-08 2022-03-29 Evolva Sa Método para produzir um glicosídeo de esteviol alvo
RU2633644C2 (ru) 2011-11-23 2017-10-16 Эвольва Са Способы ферментативного синтеза могрозидных соединений
TW201402599A (zh) * 2012-05-30 2014-01-16 Suntory Holdings Ltd 甜菊糖苷糖苷轉化酵素及編碼該酵素之基因
WO2016050890A2 (en) 2014-10-01 2016-04-07 Evolva Sa Methods and materials for biosynthesis of mogroside compounds
CA2893462A1 (en) * 2012-12-04 2014-06-12 Evolva Sa Methods and materials for biosynthesis of mogroside compounds
SG10201705993YA (en) 2013-02-11 2017-08-30 Evolva Sa Efficient production of steviol glycosides in recombinant hosts
BR112017002783A2 (pt) 2014-08-11 2017-12-19 Evolva Sa produção de glicosídeos de esteviol em hospedeiros recombinantes
MX2017003130A (es) 2014-09-09 2017-10-24 Evolva Sa Produccion de glucosidos de esteviol en hospederos recombinantes.
IL287789B2 (en) * 2014-09-11 2024-05-01 The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo Mogroside compounds, methods for their preparation, preparations including them and their uses
CA2968331C (en) 2014-10-17 2024-02-06 Suntory Holdings Limited Mogrol glycosyltransferase and gene encoding same
CA2974185A1 (en) 2015-01-20 2016-07-28 Suntory Holdings Limited Method for preparing mogroside
CA2973674A1 (en) 2015-01-30 2016-08-04 Evolva Sa Production of steviol glycosides in recombinant hosts
CN115851470A (zh) 2015-03-16 2023-03-28 帝斯曼知识产权资产管理有限公司 Udp-糖基转移酶
AU2016307066A1 (en) 2015-08-07 2018-02-08 Evolva Sa Production of steviol glycosides in recombinant hosts
EP3368542B1 (en) 2015-10-29 2022-06-22 Firmenich Incorporated High intensity sweeteners
CN106924274B (zh) * 2015-12-29 2019-01-04 成都普睿法药物研发有限公司 葫芦烷型四环三萜类化合物抗肺纤维化应用
US10982249B2 (en) 2016-04-13 2021-04-20 Evolva Sa Production of steviol glycosides in recombinant hosts
CN109312378A (zh) 2016-05-16 2019-02-05 埃沃尔瓦公司 在重组宿主中产生甜菊醇糖苷
AU2017267214A1 (en) * 2016-05-16 2018-11-15 Evolva Sa Production of steviol glycosides in recombinant hosts
EP3502265B1 (en) 2016-07-19 2020-12-02 Suntory Holdings Limited Method for producing mogrol or mogrol glycoside
US11396669B2 (en) 2016-11-07 2022-07-26 Evolva Sa Production of steviol glycosides in recombinant hosts
SG11201910136RA (en) 2017-05-03 2019-11-28 Firmenich Incorporated Methods for making high intensity sweeteners
JP7285788B2 (ja) 2017-05-19 2023-06-02 ザ コカ・コーラ カンパニー シアメノシドｉ甘味料入り組成物及びその使用
CA3064334A1 (en) 2017-06-02 2018-12-06 Givaudan Sa Compositions
US11248248B2 (en) 2017-06-15 2022-02-15 Evolva Sa Production of mogroside compounds in recombinant hosts
CN107189976B (zh) * 2017-07-28 2022-03-11 李华政 促进罗汉果ugt72b21基因表达的方法
CN110669094B (zh) * 2019-10-14 2021-12-21 上海交通大学 罗汉果新苷及其制备方法
KR102362135B1 (ko) * 2019-10-25 2022-02-14 고려대학교 산학협력단 테르펜 당쇄 부가 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 조성물
CN115605081A (zh) * 2020-03-17 2023-01-13 可口可乐公司（Us） 新的罗汉果苷生产系统和方法
CA3179775A1 (en) 2020-04-20 2021-10-28 Givaudan Sa Compositions
GB202007984D0 (en) 2020-05-28 2020-07-15 Givaudan Sa Compositions
CN112063647B (zh) * 2020-09-17 2023-05-02 云南农业大学 酿酒酵母重组菌Cuol01的构建方法、酿酒酵母重组菌Cuol02及应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6399321B1 (en) * 1999-08-18 2002-06-04 National Research Council Of Canada Methods for screening UDP-glucose:glycoprotein glucosyltransferase (UGGT) activity and nucleic acid encoding for UGGT
EP1510573A1 (en) 2003-09-01 2005-03-02 Austria Wirtschaftsservice Gesellschaft mit beschränkter Haftung Method for detoxification of mycotoxins
US20080148432A1 (en) * 2005-12-21 2008-06-19 Mark Scott Abad Transgenic plants with enhanced agronomic traits
EP1871883A1 (en) 2005-03-02 2008-01-02 Metanomics GmbH Process for the production of fine chemicals
US8257948B1 (en) * 2011-02-17 2012-09-04 Purecircle Usa Method of preparing alpha-glucosyl Stevia composition
US8956677B2 (en) 2005-11-23 2015-02-17 The Coca-Cola Company High-potency sweetener composition with glucosamine and compositions sweetened therewith
RU2437573C2 (ru) 2005-11-23 2011-12-27 Дзе Кока-Кола Компани Композиция интенсивного подсластителя с кальцием и подслащенные ею композиции
US7927851B2 (en) 2006-03-21 2011-04-19 Vineland Research And Innovation Centre Compositions having ent-kaurenoic acid 13-hydroxylase activity and methods for producing same
US20100143975A1 (en) 2006-11-22 2010-06-10 The University Of York Monoterpenoid modifying enzymes
US20100132073A1 (en) 2006-12-01 2010-05-27 The University Of York Sesquiterpenoid modifying enzymes
GB0904639D0 (en) * 2009-03-18 2009-04-29 Univ York Assay
BR112012030836B8 (pt) 2010-06-02 2024-02-06 Evolva Nutrition Inc Hospedeiro recombinante que compreende genes recombinantes para produção de esteviol ou glicosídeo de esteviol, método para produzir esteviol, glicosídeo de esteviol ou composição de glicosídeo de esteviol e método para sintetizar esteviol ou glicosídeo de esteviol
RU2633644C2 (ru) 2011-11-23 2017-10-16 Эвольва Са Способы ферментативного синтеза могрозидных соединений
CA2893462A1 (en) 2012-12-04 2014-06-12 Evolva Sa Methods and materials for biosynthesis of mogroside compounds

Also Published As

Publication number Publication date
CN103958693A (zh) 2014-07-30
RU2014125216A (ru) 2015-12-27
RU2633644C2 (ru) 2017-10-16
CN103958693B (zh) 2016-08-24
AU2012342114A1 (en) 2014-05-22
US20180237819A1 (en) 2018-08-23
CA2853677A1 (en) 2013-05-30
JP2014533518A (ja) 2014-12-15
IN2014CN03557A (pt) 2015-10-09
EP2783009B1 (en) 2016-04-13
MX342851B (es) 2016-10-14
US9920349B2 (en) 2018-03-20
MX2014006276A (es) 2014-10-13
AU2017235907A1 (en) 2017-10-12
KR101791597B1 (ko) 2017-10-30
SG11201401927PA (en) 2014-09-26
KR20140099281A (ko) 2014-08-11
US20140308698A1 (en) 2014-10-16
MY170686A (en) 2019-08-26
AU2012342114B2 (en) 2017-12-21
JP6084983B2 (ja) 2017-02-22
EP2783009A1 (en) 2014-10-01
HK1200494A1 (zh) 2015-08-07
US10738340B2 (en) 2020-08-11
WO2013076577A1 (en) 2013-05-30
CA2853677C (en) 2019-01-29

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