RU2633644C2 - Способы ферментативного синтеза могрозидных соединений - Google Patents

Способы ферментативного синтеза могрозидных соединений Download PDF

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RU2633644C2
RU2633644C2 RU2014125216A RU2014125216A RU2633644C2 RU 2633644 C2 RU2633644 C2 RU 2633644C2 RU 2014125216 A RU2014125216 A RU 2014125216A RU 2014125216 A RU2014125216 A RU 2014125216A RU 2633644 C2 RU2633644 C2 RU 2633644C2
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mogroside
recombinant
mogroside compound
mogrol
polypeptide
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RU2014125216A
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Russian (ru)
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RU2014125216A (ru
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Яоцюань Лю
Дзунг Йеоп ЛИ
Моника КХАРЕ
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Эвольва Са
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/20—Preparation of steroids containing heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
RU2014125216A 2011-11-23 2012-11-19 Способы ферментативного синтеза могрозидных соединений RU2633644C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161563303P 2011-11-23 2011-11-23
US61/563,303 2011-11-23
PCT/IB2012/002857 WO2013076577A1 (en) 2011-11-23 2012-11-19 Methods and materials for enzymatic synthesis of mogroside compounds

Publications (2)

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RU2014125216A RU2014125216A (ru) 2015-12-27
RU2633644C2 true RU2633644C2 (ru) 2017-10-16

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RU2014125216A RU2633644C2 (ru) 2011-11-23 2012-11-19 Способы ферментативного синтеза могрозидных соединений

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US (2) US9920349B2 (enExample)
EP (1) EP2783009B1 (enExample)
JP (1) JP6084983B2 (enExample)
KR (1) KR101791597B1 (enExample)
CN (1) CN103958693B (enExample)
AU (2) AU2012342114B2 (enExample)
BR (1) BR112014012543A2 (enExample)
CA (1) CA2853677C (enExample)
IN (1) IN2014CN03557A (enExample)
MX (1) MX342851B (enExample)
MY (1) MY170686A (enExample)
RU (1) RU2633644C2 (enExample)
SG (1) SG11201401927PA (enExample)
WO (1) WO2013076577A1 (enExample)

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CA2900882A1 (en) 2013-02-11 2014-08-14 Evolva Sa Efficient production of steviol glycosides in recombinants hosts
CN114410493A (zh) 2014-08-11 2022-04-29 埃沃尔瓦公司 在重组宿主中生产甜菊醇糖苷
SG11201701677UA (en) 2014-09-09 2017-04-27 Evolva Sa Production of steviol glycosides in recombinant hosts
IL287789B2 (en) 2014-09-11 2024-05-01 The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo Mogroside compounds, methods for their preparation, preparations including them and their uses
CA2963300C (en) 2014-10-01 2024-04-30 Evolva Sa Methods and materials for biosynthesis of mogroside compounds
EP3208342A4 (en) 2014-10-17 2018-07-04 Suntory Holdings Limited Mogrol glycosyltransferase and gene encoding same
WO2016117549A1 (ja) 2015-01-20 2016-07-28 サントリーホールディングス株式会社 モグロシドの調製方法
JP2018503388A (ja) 2015-01-30 2018-02-08 エヴォルヴァ エスアー．Ｅｖｏｌｖａ Ｓａ． 組み換え宿主におけるステビオールグリコシドの生産
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CA2995067A1 (en) 2015-08-07 2017-02-16 Evolva Sa Production of steviol glycosides in recombinant hosts
SG11201803603WA (en) 2015-10-29 2018-05-30 Senomyx Inc High intensity sweeteners
CN106924274B (zh) * 2015-12-29 2019-01-04 成都普睿法药物研发有限公司 葫芦烷型四环三萜类化合物抗肺纤维化应用
MY198001A (en) 2016-04-13 2023-07-25 Evolva SA Production of steviol glycoside in recombinant hosts
CN109312378A (zh) 2016-05-16 2019-02-05 埃沃尔瓦公司 在重组宿主中产生甜菊醇糖苷
US20190144907A1 (en) * 2016-05-16 2019-05-16 Evolva Sa Production of steviol glycosides in recombinant hosts
WO2018016483A1 (ja) * 2016-07-19 2018-01-25 サントリーホールディングス株式会社 モグロールまたはモグロール配糖体の生産方法
EP3535406A1 (en) 2016-11-07 2019-09-11 Evolva SA Production of steviol glycosides in recombinant hosts
CN111108213B (zh) * 2017-05-03 2024-12-13 弗门尼舍公司 制备高强度甜味剂的方法
WO2018213683A1 (en) 2017-05-19 2018-11-22 The Coca-Cola Company Siamenoside i sweetened compositions and uses of the same
RU2762719C2 (ru) 2017-06-02 2021-12-22 Живодан Са Композиция, модифицирующая сладость
US11248248B2 (en) 2017-06-15 2022-02-15 Evolva Sa Production of mogroside compounds in recombinant hosts
CN107189976B (zh) * 2017-07-28 2022-03-11 李华政 促进罗汉果ugt72b21基因表达的方法
BR112021008929A2 (pt) 2018-11-07 2021-08-17 Firmenich Incorporated métodos para fazer edulcorantes de alta intensidade
MX2021005219A (es) 2018-11-07 2021-06-18 Firmenich Incorporated Metodos para hacer edulcorantes de alta intensidad.
CA3118924A1 (en) 2018-11-09 2020-05-14 Ginkgo Bioworks, Inc. Biosynthesis of mogrosides
CN110669094B (zh) * 2019-10-14 2021-12-21 上海交通大学 罗汉果新苷及其制备方法
KR102362135B1 (ko) * 2019-10-25 2022-02-14 고려대학교 산학협력단 테르펜 당쇄 부가 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 조성물
US20240060078A1 (en) * 2020-03-17 2024-02-22 The Coca-Cola Company Novel mogroside production system and methods
CA3179775A1 (en) 2020-04-20 2021-10-28 Givaudan Sa Compositions
GB202007984D0 (en) 2020-05-28 2020-07-15 Givaudan Sa Compositions
CN112063647B (zh) * 2020-09-17 2023-05-02 云南农业大学 酿酒酵母重组菌Cuol01的构建方法、酿酒酵母重组菌Cuol02及应用
CN116064712B (zh) * 2022-10-08 2025-05-06 中国药科大学 一种罗汉果醇的生物合成方法
CN121127603A (zh) 2023-04-20 2025-12-12 帝斯曼知识产权资产管理有限公司 用于产生罗汉果苷的菌株和方法

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Publication number Publication date
EP2783009B1 (en) 2016-04-13
MY170686A (en) 2019-08-26
KR101791597B1 (ko) 2017-10-30
JP6084983B2 (ja) 2017-02-22
CA2853677A1 (en) 2013-05-30
IN2014CN03557A (enExample) 2015-10-09
BR112014012543A2 (pt) 2017-06-13
US20140308698A1 (en) 2014-10-16
CN103958693B (zh) 2016-08-24
SG11201401927PA (en) 2014-09-26
AU2017235907A1 (en) 2017-10-12
MX342851B (es) 2016-10-14
JP2014533518A (ja) 2014-12-15
US20180237819A1 (en) 2018-08-23
HK1200494A1 (zh) 2015-08-07
KR20140099281A (ko) 2014-08-11
AU2012342114A1 (en) 2014-05-22
EP2783009A1 (en) 2014-10-01
US9920349B2 (en) 2018-03-20
MX2014006276A (es) 2014-10-13
US10738340B2 (en) 2020-08-11
AU2012342114B2 (en) 2017-12-21
CN103958693A (zh) 2014-07-30
WO2013076577A1 (en) 2013-05-30
RU2014125216A (ru) 2015-12-27
CA2853677C (en) 2019-01-29

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