IL93817A - History of N- (3) -droxy-4-piperidinyl () dihydrobenzopuran, dihydro-H2- benzopyrene or dihydrobenzodeioxin (carboxamide, preparation and decontamination) - Google Patents

History of N- (3) -droxy-4-piperidinyl () dihydrobenzopuran, dihydro-H2- benzopyrene or dihydrobenzodeioxin (carboxamide, preparation and decontamination)

Info

Publication number
IL93817A
IL93817A IL9381790A IL9381790A IL93817A IL 93817 A IL93817 A IL 93817A IL 9381790 A IL9381790 A IL 9381790A IL 9381790 A IL9381790 A IL 9381790A IL 93817 A IL93817 A IL 93817A
Authority
IL
Israel
Prior art keywords
formula
hydrogen
amino
alkyl
dihydro
Prior art date
Application number
IL9381790A
Other languages
English (en)
Hebrew (he)
Other versions
IL93817A0 (en
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Priority to IL11039790A priority Critical patent/IL110397A/en
Publication of IL93817A0 publication Critical patent/IL93817A0/xx
Publication of IL93817A publication Critical patent/IL93817A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrane Compounds (AREA)
IL9381790A 1989-03-22 1990-03-20 History of N- (3) -droxy-4-piperidinyl () dihydrobenzopuran, dihydro-H2- benzopyrene or dihydrobenzodeioxin (carboxamide, preparation and decontamination) IL93817A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL11039790A IL110397A (en) 1989-03-22 1990-03-20 Carboxylic acids in cyclic acids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32694189A 1989-03-22 1989-03-22

Publications (2)

Publication Number Publication Date
IL93817A0 IL93817A0 (en) 1990-12-23
IL93817A true IL93817A (en) 1995-03-30

Family

ID=23274437

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9381790A IL93817A (en) 1989-03-22 1990-03-20 History of N- (3) -droxy-4-piperidinyl () dihydrobenzopuran, dihydro-H2- benzopyrene or dihydrobenzodeioxin (carboxamide, preparation and decontamination)

Country Status (30)

Country Link
US (12) US5374637A (fi)
EP (1) EP0389037B1 (fi)
JP (1) JP2845341B2 (fi)
KR (1) KR0163587B1 (fi)
CN (1) CN1034502C (fi)
AT (1) ATE128132T1 (fi)
AU (1) AU616838B2 (fi)
CA (1) CA2012432C (fi)
CY (1) CY1921A (fi)
DE (1) DE69022453T2 (fi)
DK (1) DK0389037T3 (fi)
DZ (1) DZ1405A1 (fi)
ES (1) ES2081340T3 (fi)
FI (1) FI101624B (fi)
GR (1) GR3017992T3 (fi)
HK (1) HK131596A (fi)
HU (2) HU221621B1 (fi)
IE (1) IE67184B1 (fi)
IL (1) IL93817A (fi)
JO (1) JO1613B1 (fi)
MA (1) MA21778A1 (fi)
MY (2) MY131911A (fi)
NO (1) NO176101C (fi)
NZ (1) NZ232964A (fi)
PT (1) PT93531B (fi)
RU (2) RU2037492C1 (fi)
TN (1) TNSN90032A1 (fi)
ZA (1) ZA902188B (fi)
ZM (1) ZM1290A1 (fi)
ZW (1) ZW3390A1 (fi)

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JPH0873463A (ja) 1994-07-05 1996-03-19 Sanwa Kagaku Kenkyusho Co Ltd ベンゾピランカルボキサミド誘導体、その塩及び製法並びに用途
KR100388255B1 (ko) * 1994-09-27 2003-10-04 얀센 파마슈티카 엔.브이. 페닐-옥소-알킬-(4-피페리디닐)벤조에이트유도체
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US6586466B2 (en) 1995-10-30 2003-07-01 Smithkline Beecham Corporation Carbohydrazide-protease inhibitors
US6096761A (en) * 1996-02-15 2000-08-01 Janssen Pharmaceutica N.V. Esters of 3-hydroxy-piperidinemethanol derivatives
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US20020128476A1 (en) * 1996-08-08 2002-09-12 Smithkline Beecham Corporation Inhibitors of cysteine protease
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CN102295594B (zh) * 2011-07-12 2016-01-20 上海医药工业研究院 4-n-取代-1-(3-甲氧基丙基)-4-哌啶胺类化合物及制备和应用
CN102942542B (zh) * 2012-11-20 2015-08-05 南京华威医药科技开发有限公司 2,3-二氢苯并呋喃类化合物的制备方法
CN103755689B (zh) * 2013-12-25 2016-06-29 连云港恒运医药科技有限公司 普卡必利降解杂质的制备方法
CN103664912B (zh) * 2013-12-31 2015-11-25 南京正大天晴制药有限公司 一种普卡必利的合成工艺
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Also Published As

Publication number Publication date
US5616738A (en) 1997-04-01
US5521314A (en) 1996-05-28
AU616838B2 (en) 1991-11-07
CA2012432C (en) 2000-11-14
RU2108332C1 (ru) 1998-04-10
US5739134A (en) 1998-04-14
IE67184B1 (en) 1996-03-06
PT93531B (pt) 1998-01-30
MY131911A (en) 2007-09-28
US5616583A (en) 1997-04-01
PT93531A (pt) 1990-11-07
NO176101B (no) 1994-10-24
CN1045781A (zh) 1990-10-03
ZA902188B (en) 1991-11-27
KR900014371A (ko) 1990-10-23
ATE128132T1 (de) 1995-10-15
US5374637A (en) 1994-12-20
DZ1405A1 (fr) 2004-09-13
EP0389037B1 (en) 1995-09-20
ES2081340T3 (es) 1996-03-01
NO901306L (no) 1990-09-24
DE69022453D1 (de) 1995-10-26
IE901040L (en) 1990-09-22
US5536733A (en) 1996-07-16
FI901421A0 (fi) 1990-03-21
GR3017992T3 (en) 1996-02-29
FI101624B1 (fi) 1998-07-31
US5552553A (en) 1996-09-03
HU901627D0 (en) 1990-06-28
HK131596A (en) 1996-07-26
AU5209190A (en) 1990-09-27
FI101624B (fi) 1998-07-31
US5576448A (en) 1996-11-19
CA2012432A1 (en) 1990-09-22
DK0389037T3 (da) 1995-10-16
CY1921A (en) 1997-03-07
NO176101C (no) 1995-02-01
NO901306D0 (no) 1990-03-21
HUT58322A (en) 1992-02-28
HU211171A9 (en) 1995-11-28
EP0389037A1 (en) 1990-09-26
IL93817A0 (en) 1990-12-23
JPH02289566A (ja) 1990-11-29
MY106407A (en) 1995-05-30
JO1613B1 (en) 1990-07-01
ZW3390A1 (en) 1991-10-23
US5602129A (en) 1997-02-11
TNSN90032A1 (fr) 1991-03-05
KR0163587B1 (ko) 1998-12-01
NZ232964A (en) 1991-07-26
US5565582A (en) 1996-10-15
MA21778A1 (fr) 1990-10-01
US5610157A (en) 1997-03-11
JP2845341B2 (ja) 1999-01-13
DE69022453T2 (de) 1996-03-28
RU2037492C1 (ru) 1995-06-19
ZM1290A1 (en) 1992-07-31
CN1034502C (zh) 1997-04-09
HU221621B1 (hu) 2002-12-28
US5554772A (en) 1996-09-10

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