ZA902188B - N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran,dihydro-2h-benzopyran or dihydrobenzodioxin)carboxamide derivatives - Google Patents

N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran,dihydro-2h-benzopyran or dihydrobenzodioxin)carboxamide derivatives

Info

Publication number
ZA902188B
ZA902188B ZA902188A ZA902188A ZA902188B ZA 902188 B ZA902188 B ZA 902188B ZA 902188 A ZA902188 A ZA 902188A ZA 902188 A ZA902188 A ZA 902188A ZA 902188 B ZA902188 B ZA 902188B
Authority
ZA
South Africa
Prior art keywords
alk
dihydrobenzodioxin
dihydrobenzofuran
benzopyran
piperidinyl
Prior art date
Application number
ZA902188A
Other languages
English (en)
Inventor
Georges Henri Paul Van Daele
Henri Paul Van Daele Georges
Frans Maria Alfons Van Keybus
Maria Alfons Van Den Key Frans
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZA902188B publication Critical patent/ZA902188B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrane Compounds (AREA)
ZA902188A 1989-03-22 1990-03-21 N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran,dihydro-2h-benzopyran or dihydrobenzodioxin)carboxamide derivatives ZA902188B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32694189A 1989-03-22 1989-03-22

Publications (1)

Publication Number Publication Date
ZA902188B true ZA902188B (en) 1991-11-27

Family

ID=23274437

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA902188A ZA902188B (en) 1989-03-22 1990-03-21 N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran,dihydro-2h-benzopyran or dihydrobenzodioxin)carboxamide derivatives

Country Status (30)

Country Link
US (12) US5374637A (xx)
EP (1) EP0389037B1 (xx)
JP (1) JP2845341B2 (xx)
KR (1) KR0163587B1 (xx)
CN (1) CN1034502C (xx)
AT (1) ATE128132T1 (xx)
AU (1) AU616838B2 (xx)
CA (1) CA2012432C (xx)
CY (1) CY1921A (xx)
DE (1) DE69022453T2 (xx)
DK (1) DK0389037T3 (xx)
DZ (1) DZ1405A1 (xx)
ES (1) ES2081340T3 (xx)
FI (1) FI101624B (xx)
GR (1) GR3017992T3 (xx)
HK (1) HK131596A (xx)
HU (2) HU221621B1 (xx)
IE (1) IE67184B1 (xx)
IL (1) IL93817A (xx)
JO (1) JO1613B1 (xx)
MA (1) MA21778A1 (xx)
MY (2) MY106407A (xx)
NO (1) NO176101C (xx)
NZ (1) NZ232964A (xx)
PT (1) PT93531B (xx)
RU (2) RU2037492C1 (xx)
TN (1) TNSN90032A1 (xx)
ZA (1) ZA902188B (xx)
ZM (1) ZM1290A1 (xx)
ZW (1) ZW3390A1 (xx)

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JPH0873463A (ja) * 1994-07-05 1996-03-19 Sanwa Kagaku Kenkyusho Co Ltd ベンゾピランカルボキサミド誘導体、その塩及び製法並びに用途
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CN100335460C (zh) * 2003-02-14 2007-09-05 和光纯药工业株式会社 使用离子交换树脂固定化铂催化剂的羟胺化合物制造方法
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CN102942542B (zh) * 2012-11-20 2015-08-05 南京华威医药科技开发有限公司 2,3-二氢苯并呋喃类化合物的制备方法
CN103755689B (zh) * 2013-12-25 2016-06-29 连云港恒运医药科技有限公司 普卡必利降解杂质的制备方法
CN103664912B (zh) * 2013-12-31 2015-11-25 南京正大天晴制药有限公司 一种普卡必利的合成工艺
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Also Published As

Publication number Publication date
CA2012432A1 (en) 1990-09-22
NO901306D0 (no) 1990-03-21
AU5209190A (en) 1990-09-27
CN1034502C (zh) 1997-04-09
FI101624B1 (fi) 1998-07-31
ES2081340T3 (es) 1996-03-01
IE67184B1 (en) 1996-03-06
US5576448A (en) 1996-11-19
HU901627D0 (en) 1990-06-28
ATE128132T1 (de) 1995-10-15
PT93531B (pt) 1998-01-30
EP0389037B1 (en) 1995-09-20
MA21778A1 (fr) 1990-10-01
KR0163587B1 (ko) 1998-12-01
US5552553A (en) 1996-09-03
RU2108332C1 (ru) 1998-04-10
MY106407A (en) 1995-05-30
FI101624B (fi) 1998-07-31
CN1045781A (zh) 1990-10-03
US5602129A (en) 1997-02-11
KR900014371A (ko) 1990-10-23
TNSN90032A1 (fr) 1991-03-05
AU616838B2 (en) 1991-11-07
NZ232964A (en) 1991-07-26
EP0389037A1 (en) 1990-09-26
MY131911A (en) 2007-09-28
US5616583A (en) 1997-04-01
DK0389037T3 (da) 1995-10-16
US5374637A (en) 1994-12-20
US5610157A (en) 1997-03-11
FI901421A0 (fi) 1990-03-21
DZ1405A1 (fr) 2004-09-13
ZM1290A1 (en) 1992-07-31
CA2012432C (en) 2000-11-14
IL93817A (en) 1995-03-30
PT93531A (pt) 1990-11-07
NO176101C (no) 1995-02-01
US5739134A (en) 1998-04-14
DE69022453D1 (de) 1995-10-26
NO901306L (no) 1990-09-24
RU2037492C1 (ru) 1995-06-19
ZW3390A1 (en) 1991-10-23
JP2845341B2 (ja) 1999-01-13
US5521314A (en) 1996-05-28
IL93817A0 (en) 1990-12-23
GR3017992T3 (en) 1996-02-29
HK131596A (en) 1996-07-26
CY1921A (en) 1997-03-07
JO1613B1 (en) 1990-07-01
US5565582A (en) 1996-10-15
US5554772A (en) 1996-09-10
US5536733A (en) 1996-07-16
HUT58322A (en) 1992-02-28
NO176101B (no) 1994-10-24
JPH02289566A (ja) 1990-11-29
IE901040L (en) 1990-09-22
HU221621B1 (hu) 2002-12-28
US5616738A (en) 1997-04-01
HU211171A9 (en) 1995-11-28
DE69022453T2 (de) 1996-03-28

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