HK131596A - N-(3-hydroxy-4-piperidinyl) (dihydro-benzofuran dihydro-2h-benzopyran or dihydro-benzodioxin) carboxamide derivatives - Google Patents
N-(3-hydroxy-4-piperidinyl) (dihydro-benzofuran dihydro-2h-benzopyran or dihydro-benzodioxin) carboxamide derivativesInfo
- Publication number
- HK131596A HK131596A HK131596A HK131596A HK131596A HK 131596 A HK131596 A HK 131596A HK 131596 A HK131596 A HK 131596A HK 131596 A HK131596 A HK 131596A HK 131596 A HK131596 A HK 131596A
- Authority
- HK
- Hong Kong
- Prior art keywords
- dihydro
- alk
- benzopyran
- piperidinyl
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32694189A | 1989-03-22 | 1989-03-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK131596A true HK131596A (en) | 1996-07-26 |
Family
ID=23274437
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK131596A HK131596A (en) | 1989-03-22 | 1996-07-18 | N-(3-hydroxy-4-piperidinyl) (dihydro-benzofuran dihydro-2h-benzopyran or dihydro-benzodioxin) carboxamide derivatives |
Country Status (30)
Country | Link |
---|---|
US (12) | US5374637A (xx) |
EP (1) | EP0389037B1 (xx) |
JP (1) | JP2845341B2 (xx) |
KR (1) | KR0163587B1 (xx) |
CN (1) | CN1034502C (xx) |
AT (1) | ATE128132T1 (xx) |
AU (1) | AU616838B2 (xx) |
CA (1) | CA2012432C (xx) |
CY (1) | CY1921A (xx) |
DE (1) | DE69022453T2 (xx) |
DK (1) | DK0389037T3 (xx) |
DZ (1) | DZ1405A1 (xx) |
ES (1) | ES2081340T3 (xx) |
FI (1) | FI101624B (xx) |
GR (1) | GR3017992T3 (xx) |
HK (1) | HK131596A (xx) |
HU (2) | HU221621B1 (xx) |
IE (1) | IE67184B1 (xx) |
IL (1) | IL93817A (xx) |
JO (1) | JO1613B1 (xx) |
MA (1) | MA21778A1 (xx) |
MY (2) | MY106407A (xx) |
NO (1) | NO176101C (xx) |
NZ (1) | NZ232964A (xx) |
PT (1) | PT93531B (xx) |
RU (2) | RU2037492C1 (xx) |
TN (1) | TNSN90032A1 (xx) |
ZA (1) | ZA902188B (xx) |
ZM (1) | ZM1290A1 (xx) |
ZW (1) | ZW3390A1 (xx) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ232396A (en) * | 1989-02-10 | 1991-07-26 | Merrell Dow Pharma | 2-(diphenylalkylamino) -1,3 nn heterocyclic compounds and pharmaceutical compositions |
GB9005014D0 (en) * | 1990-03-06 | 1990-05-02 | Janssen Pharmaceutica Nv | N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives |
FR2674849B1 (fr) * | 1991-04-02 | 1994-12-23 | Logeais Labor Jacques | Nouveaux derives de n-cyclohexyl benzamides ou thiobenzamides, leurs preparations et leurs applications en therapeutique. |
DE69229674T2 (de) * | 1991-09-12 | 2000-04-06 | Smithkline Beecham P.L.C. | 5-ht4 rezeptor antagonisten |
US5240943A (en) * | 1991-12-19 | 1993-08-31 | G. D. Searle & Co. | Benzopyran class iii antiarrhythmic agents |
EP0625149A1 (en) * | 1992-02-06 | 1994-11-23 | Smithkline Beecham Plc | Benzopyran, benzothiopyran and benzofuran derivatives as 5-ht4 antagonists |
GB9219163D0 (en) * | 1992-09-10 | 1992-10-28 | Smithkline Beecham Plc | Pharmaceuticals |
TW294595B (xx) * | 1992-11-20 | 1997-01-01 | Janssen Pharmaceutica Nv | |
GB9301660D0 (en) * | 1993-01-28 | 1993-03-17 | Smithkline Beecham Plc | Pharmaceuticals |
US6127379A (en) * | 1993-02-01 | 2000-10-03 | Smithkline Beecham P.L.C. | Benzopyran, benzothiopyran and benzofuran derivatives as 5-HT4 antagonists |
GB9312348D0 (en) * | 1993-06-16 | 1993-07-28 | Smithkline Beecham Plc | Pharmaceuticals |
JPH0820586A (ja) | 1994-07-05 | 1996-01-23 | Sanwa Kagaku Kenkyusho Co Ltd | 1−アザビシクロ[3.3.0]オクタン誘導体、その塩及び製法並びに用途 |
JPH0873463A (ja) | 1994-07-05 | 1996-03-19 | Sanwa Kagaku Kenkyusho Co Ltd | ベンゾピランカルボキサミド誘導体、その塩及び製法並びに用途 |
KR100388255B1 (ko) * | 1994-09-27 | 2003-10-04 | 얀센 파마슈티카 엔.브이. | 페닐-옥소-알킬-(4-피페리디닐)벤조에이트유도체 |
BR9509036A (pt) * | 1994-09-27 | 1997-10-14 | Janssen Pharmaceutica Nv | Derivados biciclicos de benzoato de peperidinila n-substituída |
TW490465B (en) * | 1994-11-24 | 2002-06-11 | Janssen Pharmaceutica Nv | Enterokinetic benzamide, the preparation process and the pharmaceutical compositions thereof |
TW360653B (en) * | 1995-03-01 | 1999-06-11 | Janssen Pharmaceutica Nv | A oxadiazole compound having colon motility stimulating properties, its preparation process and its pharmaceutical composition |
CZ132798A3 (cs) * | 1995-10-30 | 1999-02-17 | Smithkline Beecham Corporation | Inhibitory proteázy |
US6586466B2 (en) | 1995-10-30 | 2003-07-01 | Smithkline Beecham Corporation | Carbohydrazide-protease inhibitors |
NZ330263A (en) * | 1996-02-15 | 1999-06-29 | Janssen Pharmaceutica Nv | Esters of 3-hydroxy-piperidinemethanol derivatives to improve gastric emptying |
US6096761A (en) * | 1996-02-15 | 2000-08-01 | Janssen Pharmaceutica N.V. | Esters of 3-hydroxy-piperidinemethanol derivatives |
US20020128476A1 (en) * | 1996-08-08 | 2002-09-12 | Smithkline Beecham Corporation | Inhibitors of cysteine protease |
DZ2285A1 (fr) * | 1996-08-08 | 2002-12-25 | Smithkline Beecham Corp | Inhibiteurs de protéase de la cystéine. |
JP2002505684A (ja) * | 1997-06-18 | 2002-02-19 | メルク エンド カンパニー インコーポレーテッド | α1aアドレナリン受容体拮抗薬 |
US6037354A (en) * | 1997-06-18 | 2000-03-14 | Merck & Co., Inc. | Alpha 1a adrenergic receptor antagonists |
TW402591B (en) * | 1997-07-11 | 2000-08-21 | Janssen Pharmaceutica Nv | Monocyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives |
EP1112270B1 (en) | 1998-09-10 | 2007-03-21 | F. Hoffmann-La Roche Ag | Dihydrobenzodioxine carboxamide and ketone derivatives as 5-ht4 receptor antagonists |
AU770580B2 (en) * | 1998-11-23 | 2004-02-26 | Janssen Pharmaceutica N.V. | Use of prucalopride for the manufacture of a medicament for the treatment of dyspepsia |
TW570920B (en) * | 1998-12-22 | 2004-01-11 | Janssen Pharmaceutica Nv | 4-(aminomethyl)-piperidine benzamides for treating gastrointestinal disorders |
US20030144175A1 (en) * | 1998-12-23 | 2003-07-31 | Smithkline Beecham Corporation | Protease inhibitors |
US20030044399A1 (en) * | 1998-12-23 | 2003-03-06 | Smithkline Beecham Corporation | Method of treatment |
JO2181B1 (en) * | 1999-04-29 | 2003-04-23 | شركة جانسين فارماسوتيكا ان. في | Procalopride solution is taken by mouth |
US6583137B1 (en) | 1999-11-10 | 2003-06-24 | Smithkline Beecham Corporation | Protease inhibitors |
JP2003513924A (ja) | 1999-11-10 | 2003-04-15 | スミスクライン・ビーチャム・コーポレイション | プロテア−ゼ阻害剤 |
WO2001034599A1 (en) | 1999-11-10 | 2001-05-17 | Smithkline Beecham Corporation | Protease inhibitors |
CN1416346A (zh) * | 2000-03-21 | 2003-05-07 | 史密丝克莱恩比彻姆公司 | 蛋白酶抑制剂 |
US20040038965A1 (en) * | 2001-10-09 | 2004-02-26 | Marquis, Jr. Robert W. | Protease inhibitors |
KR100471499B1 (ko) * | 2002-01-08 | 2005-03-09 | 학교법인 이화학당 | 크로만 유도체 및 이를 활성성분으로 함유하는 약학적조성물 |
ATE295845T1 (de) * | 2002-01-16 | 2005-06-15 | Janssen Pharmaceutica Nv | Prucaloprid-n-oxid |
US7557076B2 (en) | 2002-06-06 | 2009-07-07 | The Procter & Gamble Company | Organic catalyst with enhanced enzyme compatibility |
US7169744B2 (en) * | 2002-06-06 | 2007-01-30 | Procter & Gamble Company | Organic catalyst with enhanced solubility |
AR040336A1 (es) * | 2002-06-26 | 2005-03-30 | Glaxo Group Ltd | Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto |
DE10251394A1 (de) * | 2002-11-05 | 2004-05-13 | Clariant Gmbh | Blaues Farbmittel mit besonders hoher Reinheit und positiver triboelektrischer Steuerwirkung |
WO2004072019A1 (ja) * | 2003-02-14 | 2004-08-26 | Wako Pure Chemical Industries, Ltd. | イオン交換樹脂固定化白金触媒を用いたヒドロキシルアミン化合物の製造方法 |
DE602004024200D1 (de) * | 2003-06-19 | 2009-12-31 | Janssen Pharmaceutica Nv | Heterocyclisch substituierte 4-(aminomethyl)-piperidinbenzamide als 5ht4-antagonisten |
SI1638959T1 (sl) * | 2003-06-19 | 2008-02-29 | Janssen Pharmaceutica Nv | 5HT-antagonisticni 4-(aminometil)-piperidin benzamidi |
JO2478B1 (en) * | 2003-06-19 | 2009-01-20 | جانسين فارماسوتيكا ان. في. | (Aminomethyl) -biperidine benzamides as 5 HT4 antagonists |
US20050113246A1 (en) * | 2003-11-06 | 2005-05-26 | The Procter & Gamble Company | Process of producing an organic catalyst |
SG150533A1 (en) | 2003-11-20 | 2009-03-30 | Janssen Pharmaceutica Nv | 6-alkenyl and 6-phenylalkyl substituted 2-quinolinones and 2- quinoxalinones as poly(adp-ribose) polymerase inhibitors |
NZ546990A (en) * | 2003-11-20 | 2010-03-26 | Janssen Pharmaceutica Nv | 7-Phenylalkyl substituted 2-quinolinones and 2 quinoxalinones as poly(adp-ribose) polymerase inhibitors |
UA89618C2 (ru) * | 2003-12-05 | 2010-02-25 | Янссен Фармацевтика Н.В. | 6-замещенные 2-хинолиноны и 2-хиноксалиноны как ингибиторы поли(адф-рибоза)полимеразы |
CA2568835C (en) * | 2004-06-30 | 2014-05-27 | Janssen Pharmaceutica N.V. | Quinazolinone derivatives as parp inhibitors |
AU2005259189B2 (en) * | 2004-06-30 | 2011-04-21 | Janssen Pharmaceutica N.V. | Phthalazine derivatives as PARP inhibitors |
MXPA06014541A (es) | 2004-06-30 | 2007-03-23 | Janssen Pharmaceutica Nv | Derivados de quinazolindiona como inhibidores de la poli(adp-ribosa) polimerasa. |
AR051659A1 (es) * | 2005-06-17 | 2007-01-31 | Procter & Gamble | Una composicion que comprende un catalizador organico con compatibilidada enzimatica mejorada |
GB0525661D0 (en) * | 2005-12-16 | 2006-01-25 | Glaxo Group Ltd | Novel compounds |
CA2678248C (en) | 2007-03-08 | 2016-06-28 | Janssen Pharmaceutica Nv | Quinolinone derivatives as parp and tank inhibitors |
US8404713B2 (en) * | 2007-10-26 | 2013-03-26 | Janssen Pharmaceutica Nv | Quinolinone derivatives as PARP inhibitors |
SI2271626T1 (sl) | 2008-03-27 | 2015-03-31 | Janssen Pharmaceutica, N.V. | Tetrahidrofenantridinoni in tetrahidrociklopentakinolinoni, kot inhibitorji polimerizacije PARP in tubulina |
US8168644B2 (en) * | 2008-03-27 | 2012-05-01 | Janssen Pharmaceutica Nv | Quinazolinone derivatives as tubulin polymerization inhibitors |
CN102295594B (zh) * | 2011-07-12 | 2016-01-20 | 上海医药工业研究院 | 4-n-取代-1-(3-甲氧基丙基)-4-哌啶胺类化合物及制备和应用 |
CN102942542B (zh) * | 2012-11-20 | 2015-08-05 | 南京华威医药科技开发有限公司 | 2,3-二氢苯并呋喃类化合物的制备方法 |
CN103755689B (zh) * | 2013-12-25 | 2016-06-29 | 连云港恒运医药科技有限公司 | 普卡必利降解杂质的制备方法 |
CN103664912B (zh) * | 2013-12-31 | 2015-11-25 | 南京正大天晴制药有限公司 | 一种普卡必利的合成工艺 |
US11053255B2 (en) * | 2015-06-22 | 2021-07-06 | Georgetown University | Synthesis of mahanine and related compounds |
WO2017137910A1 (en) | 2016-02-11 | 2017-08-17 | Symed Labs Limited | Processes for the preparation of highly pure prucalopride succinate and its intermediates |
AU2019351469A1 (en) | 2018-09-28 | 2021-04-15 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
CN110938064B (zh) * | 2019-11-06 | 2022-12-27 | 广东东阳光药业有限公司 | N-取代哌啶酰胺衍生物及其用途 |
CN116082319A (zh) * | 2020-06-04 | 2023-05-09 | 南京恒通医药开发有限公司 | 一种琥珀酸普芦卡必利的连续合成方法 |
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US2652399A (en) * | 1950-10-24 | 1953-09-15 | Sterling Drug Inc | Tertiary-aminoalkyl derivatives of coumarilic acids and their preparation |
US4129655A (en) * | 1976-04-26 | 1978-12-12 | Ciba-Geigy Corporation | Neuroleptic 2-piperidinoalkyl-1,4-benzodioxans |
FR2360305A1 (fr) * | 1976-08-04 | 1978-03-03 | Ile De France | Nouveaux 2,3-alkylene bis (oxy)benzamides substitues, leurs derives et leurs procedes de preparation |
JPS5328181A (en) * | 1976-08-04 | 1978-03-16 | Ile De France | Production of nove substituted 2*33alkylenebis *oxy* benzoic acid |
US4186135A (en) * | 1976-08-04 | 1980-01-29 | Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France | Substituted 2,3-alkylene bis (oxy) benzamides and derivatives and method of preparation |
FR2396757A2 (fr) * | 1977-07-08 | 1979-02-02 | Ile De France | Nouveaux 2,3-alkylene bis (oxy) benzamides substitues, leurs derives et leurs procedes de preparation |
US4281014A (en) * | 1980-06-04 | 1981-07-28 | Fmc Corporation | Stabilized compositions containing N-aminosulfenylated derivatives of carbofuran |
NL183618C (nl) * | 1980-10-08 | 1988-12-01 | Stago Bv | Koppelingssysteem voor in elkaars verlengde liggende kabelgoten. |
FR2493848B2 (fr) * | 1980-11-07 | 1986-05-16 | Delalande Sa | Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique |
EP0069481A1 (en) * | 1981-06-17 | 1983-01-12 | Beecham Group Plc | Azabicycloalkyl benzamides, process for their preparation and pharmaceutical compositions containing them |
EP0068700A1 (en) * | 1981-06-29 | 1983-01-05 | Beecham Group Plc | Azobicycloalkylbenzamides, process for their preparation and pharmaceutical compositions containing them |
EP0069482A1 (en) * | 1981-06-29 | 1983-01-12 | Beecham Group Plc | Azabicycloalkyl benzamides, process for their preparation and pharmaceutical compositions containing them |
CA1183847A (en) * | 1981-10-01 | 1985-03-12 | Georges Van Daele | N-(3-hydroxy-4-piperidinyl)benzamide derivatives |
JPS59186969A (ja) * | 1983-04-08 | 1984-10-23 | Yoshitomi Pharmaceut Ind Ltd | ベンゾフラン−およびベンゾピランカルボキサミド誘導体 |
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GB8527052D0 (en) * | 1985-11-02 | 1985-12-04 | Beecham Group Plc | Compounds |
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JPS62234083A (ja) * | 1986-02-28 | 1987-10-14 | アーバモント インク ディビーエイ アドリヤ ラボラトリーズ | 鎮吐薬または精神病治療薬として有用なカルボキサミド類 |
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NZ225152A (en) * | 1987-07-17 | 1990-04-26 | Janssen Pharmaceutica Nv | Heterocyclically substituted piperidinyl benzamides as pharmaceuticals |
ZA886585B (en) * | 1987-09-08 | 1990-05-30 | Lilly Co Eli | Specific 5-ht,antagonists |
CA1317940C (en) * | 1987-09-25 | 1993-05-18 | Georges H. P. Van Daele | Substituted n-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides |
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TW294595B (xx) * | 1992-11-20 | 1997-01-01 | Janssen Pharmaceutica Nv |
-
1990
- 1990-03-06 US US07/489,419 patent/US5374637A/en not_active Expired - Lifetime
- 1990-03-13 DK DK90200589.1T patent/DK0389037T3/da active
- 1990-03-13 DE DE69022453T patent/DE69022453T2/de not_active Expired - Fee Related
- 1990-03-13 AT AT90200589T patent/ATE128132T1/de not_active IP Right Cessation
- 1990-03-13 EP EP90200589A patent/EP0389037B1/en not_active Expired - Lifetime
- 1990-03-13 ES ES90200589T patent/ES2081340T3/es not_active Expired - Lifetime
- 1990-03-16 CA CA002012432A patent/CA2012432C/en not_active Expired - Fee Related
- 1990-03-16 NZ NZ232964A patent/NZ232964A/en unknown
- 1990-03-19 JO JO19901613A patent/JO1613B1/en active
- 1990-03-20 JP JP2068541A patent/JP2845341B2/ja not_active Expired - Fee Related
- 1990-03-20 IL IL9381790A patent/IL93817A/en unknown
- 1990-03-20 MA MA22042A patent/MA21778A1/fr unknown
- 1990-03-20 DZ DZ900052A patent/DZ1405A1/fr active
- 1990-03-20 MY MYPI90000431A patent/MY106407A/en unknown
- 1990-03-20 MY MYPI94003195A patent/MY131911A/en unknown
- 1990-03-20 ZW ZW33/90A patent/ZW3390A1/xx unknown
- 1990-03-21 NO NO901306A patent/NO176101C/no not_active IP Right Cessation
- 1990-03-21 PT PT93531A patent/PT93531B/pt not_active IP Right Cessation
- 1990-03-21 RU SU904743491A patent/RU2037492C1/ru not_active IP Right Cessation
- 1990-03-21 HU HU9001627A patent/HU221621B1/hu not_active IP Right Cessation
- 1990-03-21 ZA ZA902188A patent/ZA902188B/xx unknown
- 1990-03-21 CN CN90101524A patent/CN1034502C/zh not_active Expired - Fee Related
- 1990-03-21 FI FI901421A patent/FI101624B/fi not_active IP Right Cessation
- 1990-03-21 ZM ZM12/90A patent/ZM1290A1/xx unknown
- 1990-03-21 AU AU52091/90A patent/AU616838B2/en not_active Ceased
- 1990-03-21 KR KR1019900003782A patent/KR0163587B1/ko not_active IP Right Cessation
- 1990-03-21 IE IE104090A patent/IE67184B1/en not_active IP Right Cessation
- 1990-03-22 TN TNTNSN90032A patent/TNSN90032A1/fr unknown
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1993
- 1993-11-02 RU RU93050009A patent/RU2108332C1/ru not_active IP Right Cessation
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1994
- 1994-09-07 US US08/301,825 patent/US5552553A/en not_active Expired - Fee Related
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1995
- 1995-03-31 US US08/414,676 patent/US5521314A/en not_active Expired - Fee Related
- 1995-03-31 US US08/414,673 patent/US5616738A/en not_active Expired - Fee Related
- 1995-04-03 US US08/415,953 patent/US5565582A/en not_active Expired - Fee Related
- 1995-04-03 US US08/415,888 patent/US5554772A/en not_active Expired - Fee Related
- 1995-04-03 US US08/415,885 patent/US5576448A/en not_active Expired - Fee Related
- 1995-04-13 US US08/421,826 patent/US5739134A/en not_active Expired - Fee Related
- 1995-04-13 US US08/421,659 patent/US5536733A/en not_active Expired - Fee Related
- 1995-04-13 US US08/421,658 patent/US5616583A/en not_active Expired - Fee Related
- 1995-04-13 US US08/421,728 patent/US5610157A/en not_active Expired - Fee Related
- 1995-04-13 US US08/421,727 patent/US5602129A/en not_active Expired - Fee Related
- 1995-06-21 HU HU95P/P00311P patent/HU211171A9/hu unknown
- 1995-11-08 GR GR950403101T patent/GR3017992T3/el unknown
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1996
- 1996-07-18 HK HK131596A patent/HK131596A/xx not_active IP Right Cessation
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1997
- 1997-03-07 CY CY192197A patent/CY1921A/xx unknown
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Effective date: 20050313 |