IL250320B - Compounds active toward bromodomains - Google Patents

Compounds active toward bromodomains

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Publication number
IL250320B
IL250320B IL250320A IL25032017A IL250320B IL 250320 B IL250320 B IL 250320B IL 250320 A IL250320 A IL 250320A IL 25032017 A IL25032017 A IL 25032017A IL 250320 B IL250320 B IL 250320B
Authority
IL
Israel
Prior art keywords
bromodomains
compounds
activity against
activity
against bromodomains
Prior art date
Application number
IL250320A
Other languages
English (en)
Hebrew (he)
Other versions
IL250320A0 (en
Original Assignee
Nuevolution As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuevolution As filed Critical Nuevolution As
Publication of IL250320A0 publication Critical patent/IL250320A0/en
Publication of IL250320B publication Critical patent/IL250320B/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
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    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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