DK3191466T3 - Azetidinyloxyphenylpyrrolidinforbindelser - Google Patents
Azetidinyloxyphenylpyrrolidinforbindelser Download PDFInfo
- Publication number
- DK3191466T3 DK3191466T3 DK15763763.8T DK15763763T DK3191466T3 DK 3191466 T3 DK3191466 T3 DK 3191466T3 DK 15763763 T DK15763763 T DK 15763763T DK 3191466 T3 DK3191466 T3 DK 3191466T3
- Authority
- DK
- Denmark
- Prior art keywords
- azetidinyloxyphenylpyrrolidine compounds
- azetidinyloxyphenylpyrrolidine
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462049485P | 2014-09-12 | 2014-09-12 | |
PCT/US2015/048267 WO2016040083A1 (en) | 2014-09-12 | 2015-09-03 | Azetidinyloxyphenylpyrrolidine compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3191466T3 true DK3191466T3 (da) | 2020-01-20 |
Family
ID=54140711
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK15763763.8T DK3191466T3 (da) | 2014-09-12 | 2015-09-03 | Azetidinyloxyphenylpyrrolidinforbindelser |
Country Status (34)
Country | Link |
---|---|
US (2) | US10781202B2 (da) |
EP (1) | EP3191466B1 (da) |
JP (1) | JP6285610B2 (da) |
KR (1) | KR101857931B1 (da) |
CN (1) | CN106795137B (da) |
AP (1) | AP2017009778A0 (da) |
AR (1) | AR101696A1 (da) |
AU (1) | AU2015315533B2 (da) |
BR (1) | BR112017002852A2 (da) |
CA (1) | CA2955634A1 (da) |
CL (1) | CL2017000484A1 (da) |
CO (1) | CO2017001389A2 (da) |
CR (1) | CR20170050A (da) |
DK (1) | DK3191466T3 (da) |
EA (1) | EA030034B1 (da) |
EC (1) | ECSP17014972A (da) |
ES (1) | ES2770047T3 (da) |
HR (1) | HRP20200119T1 (da) |
HU (1) | HUE047551T2 (da) |
IL (1) | IL250378A0 (da) |
LT (1) | LT3191466T (da) |
MX (1) | MX2017003138A (da) |
NZ (1) | NZ729087A (da) |
PE (1) | PE20170328A1 (da) |
PH (1) | PH12017500459A1 (da) |
PL (1) | PL3191466T3 (da) |
PT (1) | PT3191466T (da) |
RS (1) | RS59845B1 (da) |
SG (1) | SG11201701225YA (da) |
SI (1) | SI3191466T1 (da) |
TN (1) | TN2017000047A1 (da) |
TW (1) | TW201625591A (da) |
WO (1) | WO2016040083A1 (da) |
ZA (1) | ZA201700555B (da) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2845473T3 (es) | 2013-03-14 | 2021-07-26 | Boehringer Ingelheim Int | (Bencil-ciano-metil)-amidas sustituidas de ácido 2-aza-biciclo[2.2.1]heptano-3-carboxílico inhibidores de la catepsina- C |
RS59444B1 (sr) | 2014-09-12 | 2019-11-29 | Boehringer Ingelheim Int | Spirociklični inhibitori katepsina c |
CN111333637B (zh) * | 2018-12-18 | 2022-07-29 | 武汉人福创新药物研发中心有限公司 | 苯基吡咯烷类衍生物及其制备方法 |
CN111333625B (zh) * | 2018-12-18 | 2022-10-18 | 武汉人福创新药物研发中心有限公司 | 苯基吡咯烷类化合物及其用途 |
AU2019408336B2 (en) * | 2018-12-18 | 2022-03-10 | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company | Phenylpyrrolidine compound and use thereof |
CN112409333A (zh) * | 2019-08-23 | 2021-02-26 | 湖北生物医药产业技术研究院有限公司 | 苯基吡咯烷类化合物 |
KR20240004495A (ko) | 2021-04-29 | 2024-01-11 | 쑤저우 선카디아 바이오파마수티컬즈 컴퍼니 리미티드 | 이소퀴놀론 화합물과 이의 용도 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6258833B1 (en) * | 1999-12-23 | 2001-07-10 | Icos Corporation | Cyclic AMP-specific phosphodiesterase inhibitors |
EA200300622A1 (ru) * | 2001-01-31 | 2003-12-25 | Пфайзер Продактс Инк. | Производные амидов тиазолил-, оксазолил, пирролил- и имидазолилкислот, полезные в качестве ингибиторов изоферментов pde4 |
CA2623657A1 (en) | 2005-09-29 | 2007-04-12 | Bayer Healthcare Ag | Pde inhibitors and combinations thereof for the treatment of urological disorders |
TW201206440A (en) | 2010-04-28 | 2012-02-16 | Astellas Pharma Inc | Prophylactic or therapeutic agent for diseases associated with pains in urinary organs |
TWI617553B (zh) | 2013-03-13 | 2018-03-11 | 美國禮來大藥廠 | 吖丁啶基氧苯基吡咯啶化合物 |
WO2016033776A1 (en) * | 2014-09-04 | 2016-03-10 | Eli Lilly And Company | Crystalline (2s) -3- [ (3s, 4s) -3- [ (1r) -1-hydroxyethyl] -4- (4-methoxy-3- { [1- (5-methylpyridin-2-yl) azetidin-3-yl] oxy} phenyl) -3-methylpyrrolidin-1-yl] -3-oxopropane-1, 2-diol |
-
2015
- 2015-08-26 AR ARP150102734A patent/AR101696A1/es unknown
- 2015-08-26 TW TW104127990A patent/TW201625591A/zh unknown
- 2015-09-03 SI SI201531038T patent/SI3191466T1/sl unknown
- 2015-09-03 WO PCT/US2015/048267 patent/WO2016040083A1/en active Application Filing
- 2015-09-03 CR CR20170050A patent/CR20170050A/es unknown
- 2015-09-03 US US15/506,017 patent/US10781202B2/en active Active
- 2015-09-03 EA EA201790156A patent/EA030034B1/ru not_active IP Right Cessation
- 2015-09-03 HU HUE15763763A patent/HUE047551T2/hu unknown
- 2015-09-03 PL PL15763763T patent/PL3191466T3/pl unknown
- 2015-09-03 MX MX2017003138A patent/MX2017003138A/es unknown
- 2015-09-03 CN CN201580046264.3A patent/CN106795137B/zh active Active
- 2015-09-03 AP AP2017009778A patent/AP2017009778A0/en unknown
- 2015-09-03 JP JP2017513639A patent/JP6285610B2/ja active Active
- 2015-09-03 PT PT157637638T patent/PT3191466T/pt unknown
- 2015-09-03 RS RS20200096A patent/RS59845B1/sr unknown
- 2015-09-03 BR BR112017002852A patent/BR112017002852A2/pt not_active Application Discontinuation
- 2015-09-03 TN TN2017000047A patent/TN2017000047A1/en unknown
- 2015-09-03 SG SG11201701225YA patent/SG11201701225YA/en unknown
- 2015-09-03 EP EP15763763.8A patent/EP3191466B1/en active Active
- 2015-09-03 PE PE2017000243A patent/PE20170328A1/es unknown
- 2015-09-03 NZ NZ729087A patent/NZ729087A/en not_active IP Right Cessation
- 2015-09-03 CA CA2955634A patent/CA2955634A1/en not_active Abandoned
- 2015-09-03 ES ES15763763T patent/ES2770047T3/es active Active
- 2015-09-03 DK DK15763763.8T patent/DK3191466T3/da active
- 2015-09-03 LT LTEP15763763.8T patent/LT3191466T/lt unknown
- 2015-09-03 AU AU2015315533A patent/AU2015315533B2/en not_active Ceased
- 2015-09-03 KR KR1020177006717A patent/KR101857931B1/ko active IP Right Grant
-
2017
- 2017-01-24 ZA ZA2017/00555A patent/ZA201700555B/en unknown
- 2017-01-31 IL IL250378A patent/IL250378A0/en unknown
- 2017-02-13 CO CONC2017/0001389A patent/CO2017001389A2/es unknown
- 2017-03-01 CL CL2017000484A patent/CL2017000484A1/es unknown
- 2017-03-10 PH PH12017500459A patent/PH12017500459A1/en unknown
- 2017-03-14 EC ECIEPI201714972A patent/ECSP17014972A/es unknown
-
2019
- 2019-09-13 US US16/570,422 patent/US20200002318A1/en not_active Abandoned
-
2020
- 2020-01-24 HR HRP20200119TT patent/HRP20200119T1/hr unknown
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