IL147162A0 - Process for the preparation of pure citalopram - Google Patents

Process for the preparation of pure citalopram

Info

Publication number
IL147162A0
IL147162A0 IL14716201A IL14716201A IL147162A0 IL 147162 A0 IL147162 A0 IL 147162A0 IL 14716201 A IL14716201 A IL 14716201A IL 14716201 A IL14716201 A IL 14716201A IL 147162 A0 IL147162 A0 IL 147162A0
Authority
IL
Israel
Prior art keywords
preparation
pure citalopram
citalopram
pure
Prior art date
Application number
IL14716201A
Other languages
English (en)
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of IL147162A0 publication Critical patent/IL147162A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL14716201A 2000-12-28 2001-03-07 Process for the preparation of pure citalopram IL147162A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200001943 2000-12-28
PCT/DK2001/000148 WO2001047877A2 (en) 2000-12-28 2001-03-07 Process for the preparation of pure citalopram

Publications (1)

Publication Number Publication Date
IL147162A0 true IL147162A0 (en) 2002-08-14

Family

ID=8159933

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14716201A IL147162A0 (en) 2000-12-28 2001-03-07 Process for the preparation of pure citalopram

Country Status (41)

Country Link
US (2) US6855834B2 (de)
EP (1) EP1181272B1 (de)
JP (1) JP2003519121A (de)
KR (1) KR100430746B1 (de)
CN (1) CN1366526A (de)
AR (1) AR029898A1 (de)
AT (2) ATE222899T1 (de)
AU (3) AU2001100399B4 (de)
BE (2) BE1013417A6 (de)
BG (1) BG106219A (de)
BR (1) BR0106271A (de)
CA (1) CA2359810C (de)
CH (1) CH691536A5 (de)
CZ (1) CZ293140B6 (de)
DE (1) DE60100016T2 (de)
DK (1) DK1181272T3 (de)
EA (1) EA003459B1 (de)
ES (2) ES2181663T3 (de)
FI (2) FI108640B (de)
FR (1) FR2818977B1 (de)
GB (2) GB2356199B (de)
GR (1) GR20010100131A (de)
HK (1) HK1049332A1 (de)
HR (1) HRP20020005A2 (de)
HU (2) HU0101028D0 (de)
IE (2) IES20010253A2 (de)
IL (1) IL147162A0 (de)
IS (1) IS5884A (de)
IT (1) ITMI20010604A1 (de)
MX (1) MXPA01013336A (de)
NL (1) NL1017534C1 (de)
NO (1) NO313047B1 (de)
NZ (1) NZ516299A (de)
PL (1) PL353369A1 (de)
PT (1) PT1181272E (de)
SE (1) SE0103044L (de)
SK (1) SK284418B6 (de)
TR (1) TR200200018T1 (de)
UA (1) UA71635C2 (de)
WO (1) WO2001047877A2 (de)
ZA (1) ZA200110133B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
TR200102957T2 (tr) 1999-04-14 2004-12-21 H. Lundbeck A/S Sitalopram hazırlanması için metod.
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
EP1228056B1 (de) 1999-10-25 2004-09-22 H. Lundbeck A/S Verfahren zur herstellung von citalopram
HRP20020344B1 (hr) 1999-10-25 2010-10-31 H. Lundbeck A/S Način priprave citaloprama
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
EP1246812B1 (de) 1999-12-28 2004-03-17 H. Lundbeck A/S Verfahren zur herstellung von citalopram
SI1246813T1 (en) 1999-12-30 2004-08-31 H. Lundbeck A/S Method for the preparation of citalopram
PL197821B1 (pl) 2000-01-14 2008-04-30 Lundbeck & Co As H Sposób wytwarzania 5-cyjanoftalidu
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
PL360110A1 (en) 2000-03-13 2004-09-06 H.Lundbeck A/S Method for the preparation of citalopram
BR0109364A (pt) * 2000-03-13 2002-12-24 Lundbeck & Co As H Métodos para fabricação de citalopram através de alquilação escalonada de 5-substituìda 1- (4-fluorofenil) - 1,3- diidroisobenzofuranos e citalopram
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
JP2003527386A (ja) 2000-03-14 2003-09-16 ハー・ルンドベック・アクチエゼルスカベット シタロプラムの製造方法
CH692148A5 (de) * 2000-03-16 2002-02-28 Lundbeck & Co As H Verfahren zur Herstellung von Citalopram.
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CA2354877C (en) 2000-08-18 2006-05-02 H. Lundbeck A/S Method for the preparation of citalopram
EA003581B1 (ru) 2000-12-22 2003-06-26 Х.Лундбекк А/С Способ получения чистого циталопрама
AU2001100399B4 (en) 2000-12-28 2002-03-21 H Lundbeck As Process for the preparation of pure citalopram
GB2376945A (en) * 2001-06-27 2002-12-31 Cipla Ltd Citalopram preparation
AU2003222435A1 (en) 2002-01-07 2003-07-24 Sun Pharmaceutical Industries Limited Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
ES2194597B2 (es) * 2002-01-25 2004-08-01 Esteve Quimica, S.A. Procedimiento para la obtencion de citalopram.
GB0204607D0 (en) 2002-02-27 2002-04-10 Matrix Lab Ltd Process
GB2386119A (en) * 2002-02-27 2003-09-10 Cipla Ltd Purification of citalopram
EP1346989A1 (de) * 2002-03-21 2003-09-24 Jubilant Organosys Limited Verbessertes Verfahren zur Herstellung von Citalopram und Citalopram Hydrobromid
WO2004085416A1 (en) * 2003-03-24 2004-10-07 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
US7019153B2 (en) 2003-06-10 2006-03-28 Sun Pharmaceutical Industries Limited Process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran acetamido-3-substituted-3-cephem-4-carboxylic acid
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
TWI347942B (en) * 2005-06-22 2011-09-01 Lundbeck & Co As H Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL135959C (de) 1964-12-23
GB1143703A (de) * 1965-03-18
DE1619713A1 (de) * 1967-03-29 1970-12-17 Leybold Heraeus Gmbh & Co Kg Vorrichtung zur Vakuum- und Kurzwegdestillation
DE2135085C3 (de) 1971-07-14 1981-12-03 Basf Ag, 6700 Ludwigshafen Verfahren zur Wiedergewinnung von Caprolactam aus einem Gemisch, das Caprolactam und dessen Oligomere enthält
DE2442426C2 (de) * 1974-09-05 1983-04-07 Bayer Ag, 5090 Leverkusen Diisocyanatodiketene, Verfahren zu deren Herstellung und deren Verwendung
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
IT8020902A0 (it) 1980-03-25 1980-03-25 Snia Viscosa Procedimento ed apparecchiatura per la separazione continua per via termica di miscele liquide dicomposti termolabili.
JPS6082101A (ja) 1983-10-13 1985-05-10 Mitsui Toatsu Chem Inc 高沸点重合性化合物の薄膜蒸留による精製方法
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
FR2656305B1 (fr) 1989-12-22 1992-04-10 Norsolor Sa Procede de purification du (meth)acrylate de glycidyle.
US5296507A (en) * 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
US5582692A (en) 1994-10-07 1996-12-10 Artisan Industries, Inc. Method for the purification of vitamin E
US6136991A (en) * 1996-05-21 2000-10-24 Exxon Chemical Patents Inc. Glycidyl ester adducts having increased glass transition temperatures
DE69725717T2 (de) 1996-05-21 2004-07-29 Exxonmobil Chemical Patents Inc., Baytown Reinigung von glycidylestern durch dünnschichtverdampfung
DE19626659A1 (de) * 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) * 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
CN1206207C (zh) 1997-07-08 2005-06-15 H.隆德贝克有限公司 氰酞氟苯胺的制备方法
DE19734673A1 (de) * 1997-08-11 1999-02-18 Rwe Dea Ag Verfahren zur Herstellung von metallfreien Guerbetalkoholen
UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
HUP0002953A3 (en) 1997-11-11 2002-12-28 Lundbeck & Co As H Method for preparation of citalopram and intermediates used for them
EP0965593B2 (de) * 1998-06-19 2008-12-03 Shin-Etsu Chemical Co., Ltd. Destillationsverfahren für (Meth)acryloxysilane
DE69904853T2 (de) * 1998-10-20 2003-09-04 Lundbeck As Valby H Verfahren zur herstellung von citalopram
SI1140886T1 (en) 1998-12-23 2003-08-31 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
TR200102957T2 (tr) 1999-04-14 2004-12-21 H. Lundbeck A/S Sitalopram hazırlanması için metod.
ITMI991579A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
EP1228056B1 (de) 1999-10-25 2004-09-22 H. Lundbeck A/S Verfahren zur herstellung von citalopram
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
EA003581B1 (ru) * 2000-12-22 2003-06-26 Х.Лундбекк А/С Способ получения чистого циталопрама
AU2001100399B4 (en) 2000-12-28 2002-03-21 H Lundbeck As Process for the preparation of pure citalopram
US6781003B1 (en) * 2003-06-09 2004-08-24 Aurobindo Pharma Ltd. Preparation of pure citalopram

Also Published As

Publication number Publication date
GB0105981D0 (en) 2001-05-02
IES20010632A2 (en) 2002-03-06
NO313047B1 (no) 2002-08-05
PL353369A1 (pl) 2003-11-17
CA2359810A1 (en) 2001-07-05
IES20010253A2 (en) 2002-03-06
HUP0102818A3 (en) 2003-07-28
JP2003519121A (ja) 2003-06-17
PT1181272E (pt) 2003-01-31
EP1181272A2 (de) 2002-02-27
GR20010100131A (el) 2002-10-09
MXPA01013336A (es) 2002-07-09
ES2181663T3 (es) 2003-03-01
SK18472001A3 (sk) 2002-05-09
US20020087012A1 (en) 2002-07-04
DE60100016T2 (de) 2003-04-17
ITMI20010604A1 (it) 2002-09-22
CH691536A5 (de) 2001-08-15
AT4368U1 (de) 2001-06-25
KR100430746B1 (ko) 2004-05-10
SE0103044L (sv) 2002-06-29
FR2818977B1 (fr) 2003-12-05
FI20010501A0 (fi) 2001-03-13
GB2356199A (en) 2001-05-16
EA003459B1 (ru) 2003-06-26
GB0117095D0 (en) 2001-09-05
BG106219A (bg) 2002-08-30
SK284418B6 (sk) 2005-04-01
ES2170733B1 (es) 2003-12-16
US20030178295A1 (en) 2003-09-25
ATE222899T1 (de) 2002-09-15
FI108640B (fi) 2002-02-28
DE60100016D1 (de) 2002-10-02
DK1181272T3 (da) 2002-12-30
ITMI20010604A0 (it) 2001-03-22
CZ293140B6 (cs) 2004-02-18
BE1013417A6 (fr) 2001-12-04
EA200200016A1 (ru) 2002-04-25
AU3920201A (en) 2001-07-09
BR0106271A (pt) 2002-05-21
TR200200018T1 (tr) 2002-06-21
WO2001047877A2 (en) 2001-07-05
HK1049332A1 (zh) 2003-05-09
WO2001047877A3 (en) 2001-12-27
NL1017534C1 (nl) 2001-04-26
IS5884A (is) 2002-06-28
NO20011272D0 (no) 2001-03-13
UA71635C2 (uk) 2004-12-15
HUP0102818A2 (hu) 2001-12-28
HRP20020005A2 (en) 2003-04-30
AR029898A1 (es) 2003-07-23
GB2361697A (en) 2001-10-31
AU750006B1 (en) 2002-07-11
HU0101028D0 (en) 2001-05-28
KR20020073379A (ko) 2002-09-26
US6855834B2 (en) 2005-02-15
CZ2001891A3 (cs) 2002-08-14
FI20011578A0 (fi) 2001-07-26
GB2356199B (en) 2001-10-03
NO20011272L (no) 2002-07-01
CN1366526A (zh) 2002-08-28
CA2359810C (en) 2002-11-05
HU0102818D0 (en) 2001-09-28
NZ516299A (en) 2002-12-20
AU2001100399B4 (en) 2002-03-21
ZA200110133B (en) 2003-01-13
AU2001100399A4 (en) 2001-11-01
FI109023B (fi) 2002-05-15
FR2818977A1 (fr) 2002-07-05
ES2170733A1 (es) 2002-08-01
EP1181272B1 (de) 2002-08-28
BE1013316A6 (fr) 2001-11-06
SE0103044D0 (sv) 2001-09-14

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