HUP0402269A3 - Methods for preparing o-desmethylvenlafaxine - Google Patents

Methods for preparing o-desmethylvenlafaxine

Info

Publication number
HUP0402269A3
HUP0402269A3 HU0402269A HUP0402269A HUP0402269A3 HU P0402269 A3 HUP0402269 A3 HU P0402269A3 HU 0402269 A HU0402269 A HU 0402269A HU P0402269 A HUP0402269 A HU P0402269A HU P0402269 A3 HUP0402269 A3 HU P0402269A3
Authority
HU
Hungary
Prior art keywords
desmethylvenlafaxine
preparing
methods
Prior art date
Application number
HU0402269A
Other languages
English (en)
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23309595&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0402269(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of HUP0402269A2 publication Critical patent/HUP0402269A2/hu
Publication of HUP0402269A3 publication Critical patent/HUP0402269A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HU0402269A 2001-12-04 2002-12-03 Methods for preparing o-desmethylvenlafaxine HUP0402269A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33495301P 2001-12-04 2001-12-04
PCT/US2002/038403 WO2003048104A1 (en) 2001-12-04 2002-12-03 Methods for preparing o-desmethylvenlafaxine

Publications (2)

Publication Number Publication Date
HUP0402269A2 HUP0402269A2 (hu) 2005-02-28
HUP0402269A3 true HUP0402269A3 (en) 2010-06-28

Family

ID=23309595

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0402269A HUP0402269A3 (en) 2001-12-04 2002-12-03 Methods for preparing o-desmethylvenlafaxine

Country Status (29)

Country Link
US (4) US6689912B2 (hu)
EP (1) EP1451143B9 (hu)
JP (1) JP4342312B2 (hu)
KR (1) KR100939650B1 (hu)
CN (1) CN1319934C (hu)
AR (1) AR037622A1 (hu)
AT (1) ATE403641T1 (hu)
AU (1) AU2002357049B2 (hu)
BR (1) BR0214701A (hu)
CA (1) CA2466779C (hu)
CO (1) CO5580816A2 (hu)
DE (1) DE60228118D1 (hu)
DK (1) DK1451143T3 (hu)
EC (1) ECSP045135A (hu)
ES (1) ES2311647T4 (hu)
HK (1) HK1065778A1 (hu)
HU (1) HUP0402269A3 (hu)
IL (3) IL162253A0 (hu)
MX (1) MXPA04005309A (hu)
NO (1) NO20042680L (hu)
NZ (1) NZ533316A (hu)
PL (1) PL369299A1 (hu)
PT (1) PT1451143E (hu)
RU (1) RU2317286C2 (hu)
SI (1) SI1451143T1 (hu)
TW (1) TWI260982B (hu)
UA (1) UA80543C2 (hu)
WO (1) WO2003048104A1 (hu)
ZA (1) ZA200405250B (hu)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6342533B1 (en) * 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
HUP0200898A3 (en) * 1999-04-06 2005-09-28 Sepracor Inc Derivatives of venlafaxine and methods of preparing and using the same
EP1864967A1 (en) * 2001-02-12 2007-12-12 Wyeth Method for preparing O-desmethyl-venlafaxine
UA80543C2 (en) * 2001-12-04 2007-10-10 Wyeth Corp Method for the preparation of o-desmethylvenlafaxine
AU2006265008A1 (en) * 2005-07-06 2007-01-11 Sepracor Inc. Combinations of eszopiclone and O-desmethylvenlafaxine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
EP1957470A1 (en) * 2005-12-05 2008-08-20 Wyeth Process for selective synthesis of enantiomers of substituted 1-(2-amino-1-phenyl-ethyl)-cyclohexanols
WO2007071404A1 (en) 2005-12-20 2007-06-28 Synthon B.V. Process for making desvenlafaxine
JP2008546718A (ja) * 2006-04-17 2008-12-25 テバ ファーマシューティカル インダストリーズ リミティド 実質的に純粋なｏ−デスメチルベンラファキシン及びその調製方法。
MX2007016179A (es) * 2006-04-17 2008-03-11 Teva Pharma Formas cristalinas de o-desmetilvenlafaxina.
WO2008035369A2 (en) * 2006-06-30 2008-03-27 Alembic Limited Novel form of o-desmethyl venlafaxine
CA2656167A1 (en) 2006-07-26 2008-01-31 Teva Pharmaceutical Industries Ltd. Processes for the synthesis of o-desmethylvenlafaxine
US20090069601A1 (en) * 2006-07-26 2009-03-12 Valerie Niddam-Hildesheim Processes for the synthesis of O-desmethylvenlafaxine
JP4763788B2 (ja) * 2006-07-26 2011-08-31 テバ ファーマシューティカル インダストリーズ リミティド Ｏ−デスメチルベンラファキシンの合成方法
US20090137846A1 (en) * 2006-07-26 2009-05-28 Valerie Niddam-Hildesheim Processes for the synthesis of O-Desmethylvenlafaxine
US20080221356A1 (en) * 2006-07-26 2008-09-11 Valerie Niddam-Hildesheim Processes for the synthesis of O-desmethylvenlafaxine
CA2656161A1 (en) * 2006-07-26 2008-01-31 Teva Pharmaceutical Industries Ltd. Process for the synthesis of o-desmethylvenlafaxine
WO2008013995A2 (en) * 2006-07-26 2008-01-31 Teva Pharmaceutical Industries Ltd. Tridesmethylvenlafaxine and processes for the synthesis of o-desmethylvenlafaxine
AR062266A1 (es) * 2006-08-04 2008-10-29 Medichem Sa Proceso mejorado para sintetizar base libre de desvenlafaxina y sus sales o solvatos
WO2008093142A1 (en) * 2007-01-31 2008-08-07 Generics [Uk] Limited Process for the preparation of o-desmethyl venlafaxine
US20080234516A1 (en) * 2007-03-14 2008-09-25 Valerie Niddam-Hildesheim Processes for preparing solid states of O-desmethylvenlafaxine succinate
WO2009009665A2 (en) * 2007-07-12 2009-01-15 Dr. Reddy's Laboratories, Ltd. O-desmethylvenlafaxine
WO2009010990A2 (en) * 2007-07-16 2009-01-22 Matrix Laboratories Limited Process for the preparation of o-desmethylvenlafaxine succinate polymorphic forms
WO2009034434A2 (en) * 2007-09-10 2009-03-19 Cadila Pharmaceuticals Limited An improved process for the preparation of o-desmethylvenlafaxine
CN101952240A (zh) * 2007-10-26 2011-01-19 基因里克斯(英国)有限公司 用于制备o-去甲基文拉法辛的方法
CA2706775A1 (en) * 2007-11-26 2009-06-04 Teva Pharmaceutical Industries Ltd. Crystal forms of o-desmethylvenlafaxine fumarate
WO2009084038A2 (en) * 2007-12-28 2009-07-09 Ind-Swift Laboratories Limited Improved process for the preparation of 0-desmethyl-venlafaxine
CA2717580A1 (en) * 2008-03-06 2009-12-17 Teva Pharmaceutical Industries Ltd. Processes for the preparation of o-desmethylvenlafaxine, free from its dimer impurities
EP2119696A1 (en) 2008-05-16 2009-11-18 Krka Preparation of O-desmethylvenlafaxine salts
EP2119695A1 (en) 2008-05-16 2009-11-18 Krka Preparation of O-desmethylvenlafaxine salts
US20110112200A1 (en) * 2008-06-16 2011-05-12 Valerie Niddam-Hildesheim Solid states of o-desmethylvenlafaxine salts
US20100016638A1 (en) * 2008-07-21 2010-01-21 Zdenko Hamersak Method for preparation of o-desmethylvenlafaxine using polythiolates
CN102164886A (zh) * 2008-07-30 2011-08-24 基因里克斯(英国)有限公司 用于制备o-去甲文拉法辛的方法
CZ301503B6 (cs) 2008-11-27 2010-03-24 Zentiva, A. S. Zpusob prípravy desvenlafaxinu a jeho solí
CZ200969A3 (cs) 2009-02-06 2010-06-30 Zentiva, K.S. Nové soli desvenlafaxinu a zpusob jejich prípravy
CZ2009454A3 (cs) 2009-07-15 2010-11-10 Zentiva, K. S. Zpusob prípravy desvenlafaxinu a jeho solí
KR20120064668A (ko) 2009-07-16 2012-06-19 시플라 리미티드 Ｏ-데스메틸 벤라팍신의 제조방법 및 이에 사용되는 중간체
US20110098506A1 (en) * 2009-10-26 2011-04-28 Intas Pharmaceuticals Limited Method of preparing o-desmethylvenlafaxine
US20110184067A1 (en) * 2010-01-25 2011-07-28 Intas Pharmaceuticals Ltd. O-desmethylvenlafaxine succinate polymorph & process for preparing thereof
EP2539313A2 (en) * 2010-03-29 2013-01-02 Pliva Hrvatska D.O.O. Crystal forms of o-desmethylvenlafaxine fumarate
CZ303249B6 (cs) 2010-04-06 2012-06-20 Zentiva, K.S. Zpusob výroby 4-(2-(substituovaných)-1-(1-hydroxycyklohexyl)ethyl)fenolu O-demethylací jejich methyletheru pomocí nepáchnoucích aromatických thiolu
EP2394976A1 (en) 2010-06-11 2011-12-14 LEK Pharmaceuticals d.d. Process for demethylating aromatic methyl ethers using 3-mercaptopropionic acid
JP6751200B2 (ja) 2017-02-09 2020-09-02 アール エル ファインケム プライベート リミテッド １−［２−（ジメチルアミノ）−１−（４−ヒドロキシフェニル）エチル］−シクロヘキサノール及びその塩の製造方法
CN109232189B (zh) * 2018-09-25 2021-10-08 杭州盛弗泰新材料科技有限公司 一种高纯度1-羟基芘的制备方法
CN109665966A (zh) * 2018-11-01 2019-04-23 山东蒲济医药科技有限公司 一种琥珀酸去甲文拉法辛化合物的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2741009A1 (de) * 1976-09-22 1978-03-23 Sandoz Ag 4-styryl-4-indolinol-derivate, ihre verwendung und herstellung
US4535186A (en) 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
CA1227304A (en) 1984-08-01 1987-09-29 Raymond C. Francis Delignification of pulp
GB8902209D0 (en) 1989-02-01 1989-03-22 Wyeth John And Brother Limited Preparation of cyclohexanol derivatives and novel thioamide intermediates
US6197828B1 (en) * 1998-12-01 2001-03-06 Sepracor, Inc. Derivatives of (+)-venlafaxine and methods of preparing and using the same
US6342533B1 (en) * 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
HUP0200898A3 (en) 1999-04-06 2005-09-28 Sepracor Inc Derivatives of venlafaxine and methods of preparing and using the same
AU5738700A (en) 1999-06-15 2001-01-02 American Home Products Corporation Enantiomers of o-desmethyl venlafaxine
JP2004504026A (ja) 2000-07-18 2004-02-12 バイエル　アクチェンゲゼルシャフト ヒトｄｅｓｃ１様セリンプロテアーゼの調節
EP1864967A1 (en) * 2001-02-12 2007-12-12 Wyeth Method for preparing O-desmethyl-venlafaxine
UA80543C2 (en) * 2001-12-04 2007-10-10 Wyeth Corp Method for the preparation of o-desmethylvenlafaxine

Also Published As

Publication number Publication date
IL162253A (en) 2009-02-11
BR0214701A (pt) 2004-08-31
DK1451143T3 (da) 2008-11-10
TWI260982B (en) 2006-09-01
PL369299A1 (en) 2005-04-18
ES2311647T4 (es) 2009-11-10
US20030105358A1 (en) 2003-06-05
CA2466779A1 (en) 2003-06-12
ES2311647T3 (es) 2009-02-16
US7435854B2 (en) 2008-10-14
EP1451143B1 (en) 2008-08-06
IL194034A (en) 2010-12-30
KR100939650B1 (ko) 2010-02-05
HUP0402269A2 (hu) 2005-02-28
NO20042680L (no) 2004-06-25
IL162253A0 (en) 2005-11-20
KR20050044671A (ko) 2005-05-12
JP4342312B2 (ja) 2009-10-14
CN1625546A (zh) 2005-06-08
RU2004120284A (ru) 2005-04-10
PT1451143E (pt) 2008-10-21
JP2005511681A (ja) 2005-04-28
CA2466779C (en) 2013-11-19
US6689912B2 (en) 2004-02-10
SI1451143T1 (sl) 2008-12-31
UA80543C2 (en) 2007-10-10
DE60228118D1 (de) 2008-09-18
AR037622A1 (es) 2004-11-17
US20090018365A1 (en) 2009-01-15
EP1451143A1 (en) 2004-09-01
WO2003048104A1 (en) 2003-06-12
ZA200405250B (en) 2005-12-28
HK1065778A1 (en) 2005-03-04
AU2002357049A1 (en) 2003-06-17
MXPA04005309A (es) 2004-09-13
NZ533316A (en) 2005-12-23
ATE403641T1 (de) 2008-08-15
US20070225525A1 (en) 2007-09-27
CN1319934C (zh) 2007-06-06
AU2002357049B2 (en) 2009-07-16
RU2317286C2 (ru) 2008-02-20
TW200301102A (en) 2003-07-01
ECSP045135A (es) 2004-07-23
CO5580816A2 (es) 2005-11-30
US20040158101A1 (en) 2004-08-12
EP1451143B9 (en) 2009-08-12

Similar Documents

Publication Publication Date Title
HK1065778A1 (en) Methods for preparing o-desmethylvenlafaxine
IL159994A0 (en) Process for preparing 4-aminodiphenylamine
GB0108968D0 (en) Methods
EP1419135A4 (en) PROCESS FOR THE PREPARATION OF TOLTERODINE
GB0104948D0 (en) Novel methods
GB0120042D0 (en) Methods
GB0126251D0 (en) Methods
HUP0201837A3 (en) Process for preparation n-carboxy-anhydrides
IL150043A0 (en) Method for preparing bromodifluoroacetic compounds
GB0111146D0 (en) Methods
EP1298117A3 (en) Method for preparing bromofluorenes
GB0116249D0 (en) Methods
GB0124577D0 (en) Novel methods
HU0204443D0 (en) Process for preparing fluoroformates
GB0118549D0 (en) Methods
HUP0401401A3 (en) Method for preparing 7-quinolinyl-3,5-dihydroxyhept-6-enoate
GB0118611D0 (en) Methods
HU0100459D0 (en) Method for producing dialkyl-n-alkoxy-methyl-chloroacet-anilides
GB0116076D0 (en) Methods
AU2002237362A1 (en) Methods for preparing 7alpha-hydroxy-dehydroepiandrosterone
AU2002336131A1 (en) Method for preparing 4-methylamino-4-phenylpiperidine
AU2002346864A1 (en) Method for preparing alkoxycarbonylamino-triazines
AU2002333993A1 (en) Method for preparing 4-amino-4-phenylpiperidines
GB0129338D0 (en) Vaccination
HU0104169D0 (en) Process for plain-vine-stock wine-planting

Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees
NF4A Restoration of patent protection
FD9A Lapse of provisional protection due to non-payment of fees