ATE403641T1 - Verfahren zur herstellung von o- desmethylvenlafaxin - Google Patents

Verfahren zur herstellung von o- desmethylvenlafaxin

Info

Publication number
ATE403641T1
ATE403641T1 AT02804479T AT02804479T ATE403641T1 AT E403641 T1 ATE403641 T1 AT E403641T1 AT 02804479 T AT02804479 T AT 02804479T AT 02804479 T AT02804479 T AT 02804479T AT E403641 T1 ATE403641 T1 AT E403641T1
Authority
AT
Austria
Prior art keywords
desmethylvenlafaxin
producing
Prior art date
Application number
AT02804479T
Other languages
English (en)
Inventor
Beat Weber
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23309595&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE403641(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of ATE403641T1 publication Critical patent/ATE403641T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
AT02804479T 2001-12-04 2002-12-03 Verfahren zur herstellung von o- desmethylvenlafaxin ATE403641T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33495301P 2001-12-04 2001-12-04

Publications (1)

Publication Number Publication Date
ATE403641T1 true ATE403641T1 (de) 2008-08-15

Family

ID=23309595

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02804479T ATE403641T1 (de) 2001-12-04 2002-12-03 Verfahren zur herstellung von o- desmethylvenlafaxin

Country Status (29)

Country Link
US (4) US6689912B2 (de)
EP (1) EP1451143B9 (de)
JP (1) JP4342312B2 (de)
KR (1) KR100939650B1 (de)
CN (1) CN1319934C (de)
AR (1) AR037622A1 (de)
AT (1) ATE403641T1 (de)
AU (1) AU2002357049B2 (de)
BR (1) BR0214701A (de)
CA (1) CA2466779C (de)
CO (1) CO5580816A2 (de)
DE (1) DE60228118D1 (de)
DK (1) DK1451143T3 (de)
EC (1) ECSP045135A (de)
ES (1) ES2311647T4 (de)
HK (1) HK1065778A1 (de)
HU (1) HUP0402269A3 (de)
IL (3) IL162253A0 (de)
MX (1) MXPA04005309A (de)
NO (1) NO20042680L (de)
NZ (1) NZ533316A (de)
PL (1) PL369299A1 (de)
PT (1) PT1451143E (de)
RU (1) RU2317286C2 (de)
SI (1) SI1451143T1 (de)
TW (1) TWI260982B (de)
UA (1) UA80543C2 (de)
WO (1) WO2003048104A1 (de)
ZA (1) ZA200405250B (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6342533B1 (en) * 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
EP1165487A1 (de) * 1999-04-06 2002-01-02 Sepracor Inc. Venlafaxinderivate; ihre herstellung und ihre verwendung
HUP0303128A3 (en) * 2001-02-12 2008-03-28 Wyeth Corp Novel succinate salt of o-desmethyl-venlafaxine, process for preparation thereof, its use and pharmaceutical composition containing it
UA80543C2 (en) * 2001-12-04 2007-10-10 Wyeth Corp Method for the preparation of o-desmethylvenlafaxine
MX2008000249A (es) * 2005-07-06 2008-03-18 Sepracor Inc Combinaciones de eszopiclona y o-desmetilvenlafaxina y metodos de tratamiento de menopausia y trastornos del estado de animo, ansiedad y cognitivos.
AU2006322057A1 (en) * 2005-12-05 2007-06-14 Wyeth Process for selective synthesis of enantiomers of substituted 1-(2-amino-1-phenyl-ethyl)-cyclohexanols
EP1973866A1 (de) * 2005-12-20 2008-10-01 Synthon B.V. Verfahren zur herstellung von desvenlafaxin
WO2007120923A1 (en) 2006-04-17 2007-10-25 Teva Pharmaceutical Industries Ltd. Substantially pure o-desmethylvenlafaxine and processes for preparing it
MX2007016179A (es) * 2006-04-17 2008-03-11 Teva Pharma Formas cristalinas de o-desmetilvenlafaxina.
WO2008035369A2 (en) * 2006-06-30 2008-03-27 Alembic Limited Novel form of o-desmethyl venlafaxine
CA2656167A1 (en) 2006-07-26 2008-01-31 Teva Pharmaceutical Industries Ltd. Processes for the synthesis of o-desmethylvenlafaxine
CA2656285A1 (en) * 2006-07-26 2008-01-31 Teva Pharmaceutical Industries Ltd. Processes for the synthesis of o-desmethylvenlafaxine
WO2008013990A2 (en) * 2006-07-26 2008-01-31 Teva Pharmaceutical Industries Ltd. Processes for the synthesis of o-desmethylvenlafaxine
JP4763788B2 (ja) * 2006-07-26 2011-08-31 テバ ファーマシューティカル インダストリーズ リミティド Ｏ−デスメチルベンラファキシンの合成方法
US20090069601A1 (en) * 2006-07-26 2009-03-12 Valerie Niddam-Hildesheim Processes for the synthesis of O-desmethylvenlafaxine
US20090137846A1 (en) * 2006-07-26 2009-05-28 Valerie Niddam-Hildesheim Processes for the synthesis of O-Desmethylvenlafaxine
US20080221356A1 (en) * 2006-07-26 2008-09-11 Valerie Niddam-Hildesheim Processes for the synthesis of O-desmethylvenlafaxine
WO2008015584A2 (en) * 2006-08-04 2008-02-07 Medichem, S.A. Improved process for synthesizing desvenlafaxine free base and salts or solvates thereof
WO2008093142A1 (en) * 2007-01-31 2008-08-07 Generics [Uk] Limited Process for the preparation of o-desmethyl venlafaxine
IN2009DN05509A (de) * 2007-03-14 2010-04-30 Teva Pharma
IN2010CN00695A (de) * 2007-07-12 2010-08-27 Reddys Lab Ltd Dr
US8329952B2 (en) * 2007-07-16 2012-12-11 Matrix Laboratories Limited Process for the preparation of O-desmethylvenlafaxine succinate polymorphic forms
WO2009034434A2 (en) * 2007-09-10 2009-03-19 Cadila Pharmaceuticals Limited An improved process for the preparation of o-desmethylvenlafaxine
EP2200968A1 (de) 2007-10-26 2010-06-30 Generics Ýuk¨Limited Verfahren zur herstellung von o-desmethylvenlafaxin
CA2706775A1 (en) * 2007-11-26 2009-06-04 Teva Pharmaceutical Industries Ltd. Crystal forms of o-desmethylvenlafaxine fumarate
WO2009084038A2 (en) * 2007-12-28 2009-07-09 Ind-Swift Laboratories Limited Improved process for the preparation of 0-desmethyl-venlafaxine
EP2252574A1 (de) * 2008-03-06 2010-11-24 Teva Pharmaceutical Industries Ltd. Verfahren zur herstellung von dimer-unreinheitsfreiem o-desmethylvenlafaxin
EP2119695A1 (de) 2008-05-16 2009-11-18 Krka Zubereitung von O-Desmethylvenlafaxin-Salzen
EP2119696A1 (de) 2008-05-16 2009-11-18 Krka Zubereitung von O-Desmethylvenlafaxin-Salzen
EP2297087A2 (de) * 2008-06-16 2011-03-23 Teva Pharmaceutical Industries Ltd. Feste formen von o-desmethylvenlafaxinsalzen
US20100016638A1 (en) * 2008-07-21 2010-01-21 Zdenko Hamersak Method for preparation of o-desmethylvenlafaxine using polythiolates
AU2009275667A1 (en) * 2008-07-30 2010-02-04 Generics [Uk] Limited Process for the preparation of O-desmethylvenlafaxine
CZ2008756A3 (cs) 2008-11-27 2010-03-24 Zentiva, A. S. Zpusob prípravy desvenlafaxinu a jeho solí
CZ200969A3 (cs) 2009-02-06 2010-06-30 Zentiva, K.S. Nové soli desvenlafaxinu a zpusob jejich prípravy
CZ302145B6 (cs) 2009-07-15 2010-11-10 Zentiva, K. S. Zpusob prípravy desvenlafaxinu a jeho solí
NZ597550A (en) 2009-07-16 2013-08-30 Cipla Ltd Process for the preparation of o-desmethyl venlafaxine and intermediate for use therein
US20110098506A1 (en) * 2009-10-26 2011-04-28 Intas Pharmaceuticals Limited Method of preparing o-desmethylvenlafaxine
US20110184067A1 (en) * 2010-01-25 2011-07-28 Intas Pharmaceuticals Ltd. O-desmethylvenlafaxine succinate polymorph & process for preparing thereof
CA2795023A1 (en) 2010-03-29 2011-10-06 Pliva Hrvatska D.O.O. Crystal forms of o-desmethylvenlafaxine fumarate
CZ303249B6 (cs) 2010-04-06 2012-06-20 Zentiva, K.S. Zpusob výroby 4-(2-(substituovaných)-1-(1-hydroxycyklohexyl)ethyl)fenolu O-demethylací jejich methyletheru pomocí nepáchnoucích aromatických thiolu
EP2394976A1 (de) 2010-06-11 2011-12-14 LEK Pharmaceuticals d.d. Verfahren zur Demethylierung aromatischer Methylether unter Verwendung von 3-Mercaptopropionsäure
EP3580198B1 (de) 2017-02-09 2023-08-09 R L Finechem Private Limited Verfahren zur herstellung of1-[2-(dimethylamino)-1-(4-hydroxyphenyl) ethyl]-cyclohexanol und salzen davon
CN109232189B (zh) * 2018-09-25 2021-10-08 杭州盛弗泰新材料科技有限公司 一种高纯度1-羟基芘的制备方法
CN109665966A (zh) * 2018-11-01 2019-04-23 山东蒲济医药科技有限公司 一种琥珀酸去甲文拉法辛化合物的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2741009A1 (de) * 1976-09-22 1978-03-23 Sandoz Ag 4-styryl-4-indolinol-derivate, ihre verwendung und herstellung
US4535186A (en) 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
CA1227304A (en) 1984-08-01 1987-09-29 Raymond C. Francis Delignification of pulp
GB8902209D0 (en) 1989-02-01 1989-03-22 Wyeth John And Brother Limited Preparation of cyclohexanol derivatives and novel thioamide intermediates
US6342533B1 (en) * 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
US6197828B1 (en) * 1998-12-01 2001-03-06 Sepracor, Inc. Derivatives of (+)-venlafaxine and methods of preparing and using the same
EP1165487A1 (de) 1999-04-06 2002-01-02 Sepracor Inc. Venlafaxinderivate; ihre herstellung und ihre verwendung
AU5738700A (en) 1999-06-15 2001-01-02 American Home Products Corporation Enantiomers of o-desmethyl venlafaxine
AU2001281967A1 (en) 2000-07-18 2002-01-30 Bayer Aktiengesellschaft Regulation of human desc1-like serine protease
HUP0303128A3 (en) * 2001-02-12 2008-03-28 Wyeth Corp Novel succinate salt of o-desmethyl-venlafaxine, process for preparation thereof, its use and pharmaceutical composition containing it
UA80543C2 (en) 2001-12-04 2007-10-10 Wyeth Corp Method for the preparation of o-desmethylvenlafaxine

Also Published As

Publication number Publication date
EP1451143B1 (de) 2008-08-06
JP4342312B2 (ja) 2009-10-14
AR037622A1 (es) 2004-11-17
ECSP045135A (es) 2004-07-23
EP1451143B9 (de) 2009-08-12
CN1319934C (zh) 2007-06-06
CN1625546A (zh) 2005-06-08
US20070225525A1 (en) 2007-09-27
BR0214701A (pt) 2004-08-31
PL369299A1 (en) 2005-04-18
SI1451143T1 (sl) 2008-12-31
KR20050044671A (ko) 2005-05-12
IL162253A (en) 2009-02-11
US20090018365A1 (en) 2009-01-15
CA2466779A1 (en) 2003-06-12
WO2003048104A1 (en) 2003-06-12
US20030105358A1 (en) 2003-06-05
KR100939650B1 (ko) 2010-02-05
JP2005511681A (ja) 2005-04-28
TW200301102A (en) 2003-07-01
RU2004120284A (ru) 2005-04-10
HUP0402269A3 (en) 2010-06-28
ES2311647T3 (es) 2009-02-16
ZA200405250B (en) 2005-12-28
ES2311647T4 (es) 2009-11-10
TWI260982B (en) 2006-09-01
AU2002357049A1 (en) 2003-06-17
UA80543C2 (en) 2007-10-10
EP1451143A1 (de) 2004-09-01
IL194034A (en) 2010-12-30
US20040158101A1 (en) 2004-08-12
MXPA04005309A (es) 2004-09-13
HUP0402269A2 (hu) 2005-02-28
DK1451143T3 (da) 2008-11-10
US7435854B2 (en) 2008-10-14
RU2317286C2 (ru) 2008-02-20
CA2466779C (en) 2013-11-19
CO5580816A2 (es) 2005-11-30
AU2002357049B2 (en) 2009-07-16
HK1065778A1 (en) 2005-03-04
NZ533316A (en) 2005-12-23
US6689912B2 (en) 2004-02-10
NO20042680L (no) 2004-06-25
PT1451143E (pt) 2008-10-21
DE60228118D1 (de) 2008-09-18
IL162253A0 (en) 2005-11-20

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