ATE296287T1 - Verfahren zur herstellung von repaglinide - Google Patents

Verfahren zur herstellung von repaglinide

Info

Publication number
ATE296287T1
ATE296287T1 AT02775017T AT02775017T ATE296287T1 AT E296287 T1 ATE296287 T1 AT E296287T1 AT 02775017 T AT02775017 T AT 02775017T AT 02775017 T AT02775017 T AT 02775017T AT E296287 T1 ATE296287 T1 AT E296287T1
Authority
AT
Austria
Prior art keywords
repaglinide
producing
producing repaglinide
Prior art date
Application number
AT02775017T
Other languages
English (en)
Inventor
Purna Chandra Ray
Jayachandra Suresh Babu
Mohammad Salman
Naresh Kumar
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Application granted granted Critical
Publication of ATE296287T1 publication Critical patent/ATE296287T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
AT02775017T 2001-09-25 2002-09-24 Verfahren zur herstellung von repaglinide ATE296287T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN983DE2001 IN192527B (de) 2001-09-25 2001-09-25
PCT/IB2002/003943 WO2003027072A1 (en) 2001-09-25 2002-09-24 Process for the preparation of repaglinide

Publications (1)

Publication Number Publication Date
ATE296287T1 true ATE296287T1 (de) 2005-06-15

Family

ID=11097115

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02775017T ATE296287T1 (de) 2001-09-25 2002-09-24 Verfahren zur herstellung von repaglinide

Country Status (13)

Country Link
US (1) US7148355B2 (de)
EP (1) EP1432682B1 (de)
JP (1) JP2005521634A (de)
CN (1) CN1571769A (de)
AR (1) AR036623A1 (de)
AT (1) ATE296287T1 (de)
BR (1) BR0212772A (de)
CA (1) CA2461087A1 (de)
DE (1) DE60204334T2 (de)
ES (1) ES2242068T3 (de)
IN (1) IN192527B (de)
PT (1) PT1432682E (de)
WO (1) WO2003027072A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040102477A1 (en) * 2002-08-23 2004-05-27 Dr. Reddy's Laboratories Limited Polymorphic forms of (S)-Repaglinide and the processes for preparation thereof
US7915421B2 (en) * 2003-05-14 2011-03-29 Cilag Ltd. Method for preparing phenyl acetic acid derivatives
WO2004103983A1 (en) * 2003-05-26 2004-12-02 Biocon Limited Process for the preparation of s(+)-2-ethoxy-4-[n-{1-(2-piperidinophelyl)-3-methyl-1- butyl} aminocarbonylmethyl]benzoic acid derivatives
CN100445275C (zh) * 2006-06-21 2008-12-24 浙江大学 一种合成瑞格列奈的工艺
US8101769B2 (en) 2007-02-15 2012-01-24 Actavis Group Ptc Ehf Process for preparing ethyl (S)-2-ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonyl methyl]benzoate and use thereof for the preparation of Repaglinide
CN101772491A (zh) * 2007-06-06 2010-07-07 阿克塔维什集团Ptc公司 基本不含有二聚体杂质的瑞格列奈
CN101481363B (zh) * 2008-01-10 2011-05-04 江苏豪森药业股份有限公司 一种制备瑞格列奈的方法
CN101220007B (zh) * 2008-01-16 2010-09-15 浙江耐司康药业有限公司 一种制备瑞格列奈的方法
CN102267959B (zh) * 2011-07-06 2013-05-01 海南锦瑞制药股份有限公司 一种瑞格列奈晶体、其制备方法及含有该晶体的固体口服制剂
CN103012319B (zh) * 2011-09-20 2015-06-10 浙江九洲药业股份有限公司 瑞格列奈中间体的合成工艺改进
CN102633750A (zh) * 2012-03-26 2012-08-15 浙江昂利康制药有限公司 一锅法合成治疗糖尿病的药物瑞格列奈
CN102731436A (zh) * 2012-04-09 2012-10-17 海南中化联合制药工业股份有限公司 一种瑞格列奈的制备及精制方法
CN104557778A (zh) * 2015-01-09 2015-04-29 蔡伦 一种瑞格列奈的制备方法及其应用
CN105198838A (zh) * 2015-10-21 2015-12-30 河南普瑞制药有限公司 一种瑞格列奈的制备方法
CN105906583B (zh) * 2015-12-23 2018-03-09 嘉实（湖南）医药科技有限公司 一种瑞格列奈中间体的制备工艺

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5965094A (ja) * 1982-10-06 1984-04-13 Sumitomo Chem Co Ltd セフアロスポリン化合物の製造法
US5312924A (en) 1983-12-30 1994-05-17 Dr. Karl Thomae Gmbh Phenylacetic acid benzylamides

Also Published As

Publication number Publication date
PT1432682E (pt) 2005-09-30
EP1432682B1 (de) 2005-05-25
CA2461087A1 (en) 2003-04-03
DE60204334D1 (de) 2005-06-30
WO2003027072A1 (en) 2003-04-03
BR0212772A (pt) 2004-10-13
US20050107614A1 (en) 2005-05-19
JP2005521634A (ja) 2005-07-21
ES2242068T3 (es) 2005-11-01
DE60204334T2 (de) 2006-03-23
EP1432682A1 (de) 2004-06-30
US7148355B2 (en) 2006-12-12
CN1571769A (zh) 2005-01-26
AR036623A1 (es) 2004-09-22
IN192527B (de) 2004-04-24

Similar Documents

Publication Publication Date Title
DE60221399D1 (de) Verfahren zur herstellung von mitteldistillaten
ATE403641T1 (de) Verfahren zur herstellung von o- desmethylvenlafaxin
ATE386736T1 (de) Verfahren zur herstellung von benzimidazol-2-yl - chinolinonderivaten
ATE468309T1 (de) Verfahren zur herstellung von olefinen
AT7110U9 (de) Verfahren zur herstellung von amlodipinmaleat
DE60230908D1 (de) Verfahren zur herstellung von polyarylenethern
ATE296287T1 (de) Verfahren zur herstellung von repaglinide
DE50102444D1 (de) Verfahren zur herstellung von isocyanatoorganosilanen
ATE316518T1 (de) Verfahren zur herstellung von (r)-2-alkyl-3- phenyl-1-propanolen
DE50111560D1 (de) Verfahren zur herstellung von guerbetalkoholen
ATE441662T1 (de) Verfahren zur herstellung von echinocandinderivaten
ATE360610T1 (de) Verfahren zur herstellung von cilastatin
DE60003264D1 (de) Verfahren zur herstellung von glycerylethern
ATE287870T1 (de) Verfahren zur herstellung von phenethylamin- derivaten
DE60103173D1 (de) Verfahren zur herstellung von 3-amino-2-chlor-4-methylpyridin
DE60210911D1 (de) Verfahren zur Herstellung von dehnungserfassenden Vorrichtungen
DE50303611D1 (de) Verfahren zur herstellung von polyisobuten
ATE273315T1 (de) Verfahren zur herstellung von n- phosphonomethyliminodiessigsäure
DE50200870D1 (de) Verfahren zur herstellung von hydroxyalkylpolysiloxanen
DE50006772D1 (de) Verfahren zur herstellung von oxindolen
ATE402138T1 (de) Verfahren zur herstellung von 2- aminoindanderivaten
DE60105991D1 (de) Verfahren zur herstellung von 6-aminocapronamid
ATE437879T1 (de) Verfahren zur herstellung von imipenem
DE60230422D1 (de) Verfahren zur herstellung von kohlenwasserstoffen
DE50001895D1 (de) Verfahren zur herstellung von phosphonomethylglycin

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties