ATE402138T1 - Verfahren zur herstellung von 2- aminoindanderivaten - Google Patents

Verfahren zur herstellung von 2- aminoindanderivaten

Info

Publication number
ATE402138T1
ATE402138T1 AT03711939T AT03711939T ATE402138T1 AT E402138 T1 ATE402138 T1 AT E402138T1 AT 03711939 T AT03711939 T AT 03711939T AT 03711939 T AT03711939 T AT 03711939T AT E402138 T1 ATE402138 T1 AT E402138T1
Authority
AT
Austria
Prior art keywords
aminoindanderivates
producing
Prior art date
Application number
AT03711939T
Other languages
English (en)
Inventor
Mahavir Prashad
Olivier Lohse
Bin Hu
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE402138T1 publication Critical patent/ATE402138T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
    • C07C209/50—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/62—Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/41—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems
    • C07C211/42—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems with six-membered aromatic rings being part of the condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C233/06—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
    • C07C233/32—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
    • C07C233/33—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
AT03711939T 2002-03-08 2003-03-07 Verfahren zur herstellung von 2- aminoindanderivaten ATE402138T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36273502P 2002-03-08 2002-03-08

Publications (1)

Publication Number Publication Date
ATE402138T1 true ATE402138T1 (de) 2008-08-15

Family

ID=27805221

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03711939T ATE402138T1 (de) 2002-03-08 2003-03-07 Verfahren zur herstellung von 2- aminoindanderivaten

Country Status (16)

Country Link
US (1) US6933410B2 (de)
EP (1) EP1487781B8 (de)
JP (1) JP4376065B2 (de)
KR (1) KR100968650B1 (de)
CN (1) CN1268605C (de)
AR (1) AR038746A1 (de)
AT (1) ATE402138T1 (de)
AU (1) AU2003218704A1 (de)
DE (1) DE60322356D1 (de)
EG (1) EG23462A (de)
ES (1) ES2311092T3 (de)
MY (1) MY131849A (de)
PE (1) PE20031054A1 (de)
PT (1) PT1487781E (de)
TW (1) TWI284528B (de)
WO (1) WO2003076387A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
GB0426164D0 (en) 2004-11-29 2004-12-29 Novartis Ag Organic compounds
US20080027834A1 (en) * 2006-07-31 2008-01-31 Caterpillar Inc. Systems and methods for inventory management
CN103539677B (zh) * 2012-07-16 2015-04-22 武汉万知生物医药有限公司 一种5,6-二乙基-2,3-二氢-1h-茚-2-胺盐酸盐的制备方法
CN103360264B (zh) * 2013-07-18 2014-11-26 武汉恒和达生物医药有限公司 茚达特罗氨基片段5,6-二乙基-2,3-二氢-1h-茚-2-胺盐酸盐的合成方法
CN114403335A (zh) * 2014-12-09 2022-04-29 以西结·戈兰 酒精饮料替代品
US10137096B2 (en) 2014-12-09 2018-11-27 Ezekiel Golan Binge behavior regulators
US10059653B2 (en) 2015-01-20 2018-08-28 Olon S.P.A. Process for the preparation of indanamine derivatives and new synthesis intermediates
ITUB20153978A1 (it) 2015-09-28 2017-03-28 Laboratorio Chimico Int S P A Procedimento per la preparazione di derivati di indanammina e di nuovi intermedi di sintesi.
CN108752220A (zh) * 2018-05-18 2018-11-06 成都伊诺达博医药科技有限公司 一种茚达特罗中间体的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3226947A1 (de) * 1982-07-19 1984-01-19 Henkel KGaA, 4000 Düsseldorf Feuchtwischbezug fuer die fussbodenreinigung
DE3623944A1 (de) 1986-07-16 1988-02-11 Thomae Gmbh Dr K Neue benzolsulfonamido-indanylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
ATE266662T1 (de) 1998-07-22 2004-05-15 Daiichi Suntory Pharma Co Ltd Nf-kappa b inhibitoren, die indanderivate als aktiven bestandteil enthalten
GB9913083D0 (en) 1999-06-04 1999-08-04 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
KR20040104490A (ko) 2004-12-10
PT1487781E (pt) 2008-10-30
TWI284528B (en) 2007-08-01
US6933410B2 (en) 2005-08-23
AU2003218704A8 (en) 2003-09-22
EP1487781B8 (de) 2009-06-03
JP2005519133A (ja) 2005-06-30
CN1639111A (zh) 2005-07-13
KR100968650B1 (ko) 2010-07-06
AU2003218704A1 (en) 2003-09-22
MY131849A (en) 2007-09-28
TW200305393A (en) 2003-11-01
PE20031054A1 (es) 2004-04-16
JP4376065B2 (ja) 2009-12-02
EP1487781B1 (de) 2008-07-23
WO2003076387A2 (en) 2003-09-18
WO2003076387A3 (en) 2004-03-25
EG23462A (en) 2005-10-04
AR038746A1 (es) 2005-01-26
ES2311092T3 (es) 2009-02-01
US20030187301A1 (en) 2003-10-02
CN1268605C (zh) 2006-08-09
DE60322356D1 (de) 2008-09-04
EP1487781A2 (de) 2004-12-22

Similar Documents

Publication Publication Date Title
DE60221399D1 (de) Verfahren zur herstellung von mitteldistillaten
ATE403641T1 (de) Verfahren zur herstellung von o- desmethylvenlafaxin
ATE340819T1 (de) Verfahren zur herstellung von polyamiden
ATE515500T1 (de) Verfahren zur herstellung von telmisartan
ATA11912002A (de) Verfahren zur herstellung von fälschungssicheren identifikationsmerkmalen
DE60230908D1 (de) Verfahren zur herstellung von polyarylenethern
DE60327788D1 (de) Verfahren zur herstellung von polytrimethylenterephthalt-fasern
DE50308650D1 (de) Verfahren zur herstellung von cellulosecarbamatformkörpern
DE60330050D1 (de) Verfahren zur herstellung von pyrimidinverbindungen
ATE553103T1 (de) Verfahren zur herstellung von (s)-pantoprazol
ATE456569T1 (de) Verfahren zur herstellung von 6-alkyliden- penemderivaten
ATE296287T1 (de) Verfahren zur herstellung von repaglinide
DE602004022134D1 (de) Verfahren zur herstellung von dinitrilen
ATE336478T1 (de) Verfahren zur herstellung von benzophenonen
DE50303611D1 (de) Verfahren zur herstellung von polyisobuten
ATE453619T1 (de) Verfahren zur herstellung von hydroperoxiden
ATE441662T1 (de) Verfahren zur herstellung von echinocandinderivaten
DE502004004318D1 (de) Verfahren zur herstellung von metall-matrix-verbundwerkstoffen
DE50200870D1 (de) Verfahren zur herstellung von hydroxyalkylpolysiloxanen
ATE402138T1 (de) Verfahren zur herstellung von 2- aminoindanderivaten
ATE371642T1 (de) Verfahren zur herstellung von 3- methylthiopropanal
DE60336173D1 (de) Verfahren zur herstellung von vanadylpyrophosphat-katalysatoren
ATE471941T1 (de) Verfahren zur herstellung von thiazolopyrimidinen
ATE382621T1 (de) Verfahren zur herstellung von nevirapin
ATE442352T1 (de) Verfahren zur herstellung von modafinil

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1487781

Country of ref document: EP