HUP0400382A2 - Késleltetett leadású készítmény és eljárás annak előállítására - Google Patents
Késleltetett leadású készítmény és eljárás annak előállításáraInfo
- Publication number
- HUP0400382A2 HUP0400382A2 HU0400382A HUP0400382A HUP0400382A2 HU P0400382 A2 HUP0400382 A2 HU P0400382A2 HU 0400382 A HU0400382 A HU 0400382A HU P0400382 A HUP0400382 A HU P0400382A HU P0400382 A2 HUP0400382 A2 HU P0400382A2
- Authority
- HU
- Hungary
- Prior art keywords
- release
- sustained
- producing
- same
- release composition
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 238000013268 sustained release Methods 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 2
- 230000003111 delayed effect Effects 0.000 abstract 2
- XBBVURRQGJPTHH-UHFFFAOYSA-N 2-hydroxyacetic acid;2-hydroxypropanoic acid Chemical compound OCC(O)=O.CC(O)C(O)=O XBBVURRQGJPTHH-UHFFFAOYSA-N 0.000 abstract 1
- 108010010803 Gelatin Proteins 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 239000008273 gelatin Substances 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Abstract
A találmány tárgyát képezi egy késleltetett leadású készítmény, amelyegy fiziológiailag aktív anyagot nagy mennyiségben tartalmaz még akkoris, ha a készítmény nem tartalmaz zselatint, és elnyomja a hatóanyagkezdeti túlzott mértékű felszabadulását és ezért képes stabil leadásisebességet biztosítani körülbelül 1 hónapig. A találmány tárgya ennekmegfelelően egy körülbelül 1,90 vagy kisebb szám szerinti átlagosmolekulatömeghez viszonyított tömeg szerinti átlagos molekulatömeg-aránnyal rendelkező tejsav-glikolsav polimert és egy fiziológiailagaktív anyagot tartalmazó késleltetett leadású készítmény. Ó
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001-199462 | 2001-06-29 | ||
JP2001199462 | 2001-06-29 | ||
JP2001340980 | 2001-11-06 | ||
JP2001-340980 | 2001-11-06 | ||
PCT/JP2002/006526 WO2003002091A2 (en) | 2001-06-29 | 2002-06-28 | Sustained-release composition comprising lactic acid-glycolic acid copolymer and process for producing the same |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0400382A2 true HUP0400382A2 (hu) | 2004-12-28 |
HUP0400382A3 HUP0400382A3 (en) | 2010-01-28 |
HU230152B1 HU230152B1 (hu) | 2015-09-28 |
Family
ID=26617908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0400382A HU230152B1 (hu) | 2001-06-29 | 2002-06-28 | Késleltetett leadású készítmény és eljárás annak előállítására |
Country Status (32)
Country | Link |
---|---|
US (3) | US20040241229A1 (hu) |
EP (2) | EP2108363A1 (hu) |
JP (3) | JP5491318B2 (hu) |
KR (3) | KR20090096755A (hu) |
CN (1) | CN1535141B (hu) |
AR (1) | AR034640A1 (hu) |
AT (1) | ATE429903T1 (hu) |
AU (1) | AU2002311630B2 (hu) |
BR (1) | BR0210572A (hu) |
CA (1) | CA2451718C (hu) |
CO (1) | CO5540368A2 (hu) |
CY (1) | CY1109272T1 (hu) |
CZ (1) | CZ306388B6 (hu) |
DE (1) | DE60232147D1 (hu) |
DK (1) | DK1399133T4 (hu) |
ES (1) | ES2324156T5 (hu) |
HK (1) | HK1061802A1 (hu) |
HU (1) | HU230152B1 (hu) |
IL (1) | IL159060A0 (hu) |
MX (1) | MXPA03011440A (hu) |
MY (1) | MY139606A (hu) |
NO (1) | NO333531B1 (hu) |
NZ (1) | NZ529968A (hu) |
PE (1) | PE20030069A1 (hu) |
PL (1) | PL212531B1 (hu) |
PT (1) | PT1399133E (hu) |
RU (2) | RU2297240C2 (hu) |
SI (1) | SI1399133T2 (hu) |
SK (1) | SK287568B6 (hu) |
TW (1) | TWI225416B (hu) |
WO (1) | WO2003002091A2 (hu) |
ZA (1) | ZA200309153B (hu) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2605402T3 (es) * | 2002-06-25 | 2017-03-14 | Takeda Pharmaceutical Company Limited | Procedimiento para producir una composición de liberación sostenida |
KR100684682B1 (ko) * | 2002-09-24 | 2007-02-22 | 아사히 가세이 케미칼즈 가부시키가이샤 | 글리콜산 공중합체 및 그의 제조 방법 |
TW200529890A (en) * | 2004-02-10 | 2005-09-16 | Takeda Pharmaceutical | Sustained-release preparations |
TW200613012A (en) * | 2004-07-02 | 2006-05-01 | Takeda Pharmaceuticals Co | Sustained-release composition, process for producing the same and use of the same |
DE602006000381T2 (de) * | 2005-04-28 | 2008-12-18 | Nipro Corp., Osaka | Bioabsorbierbare pharmazeutische Zusammensetzung enthaltend einen PLGA-Copolymer |
MX2008009125A (es) | 2006-01-18 | 2008-10-23 | Qps Llc | Composiciones farmaceuticas con estabilidad mejorada. |
ES2791698T3 (es) | 2006-12-18 | 2020-11-05 | Takeda Pharmaceuticals Co | Composición de liberación sostenida y método para producir la misma |
FI3660073T3 (fi) | 2007-02-15 | 2023-09-11 | Tolmar International Ltd | Matalan purskeen poly(laktidi-ko-glykolidi) |
KR101008462B1 (ko) * | 2007-07-26 | 2011-01-14 | 조남열 | 치어류 이동용 어도 장치 |
KR100969641B1 (ko) * | 2007-11-12 | 2010-07-14 | 민선영 | 저수지의 제방용 어도 |
KR100969642B1 (ko) * | 2007-11-15 | 2010-07-12 | 민선영 | 하천의 보용 어도 |
US8641900B2 (en) | 2009-11-05 | 2014-02-04 | Taiwan Biotech Co., Ltd | Method and device for continuously preparing microspheres, and collection unit thereof |
TWI477266B (zh) * | 2009-11-05 | 2015-03-21 | Taiwan Biotech Co Ltd | 連續製備微粒的方法、裝置及其收集單元 |
WO2012140487A1 (en) * | 2011-04-11 | 2012-10-18 | Cellcura Asa | Protein-free culture media products for manufacturing viral-based vaccines |
EP2873455B1 (en) * | 2012-07-12 | 2021-07-07 | Takeda Pharmaceutical Company Limited | Method for manufacturing microcapsule powder |
RU2572992C2 (ru) * | 2012-08-28 | 2016-01-20 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Курская государственная сельскохозяйственная академия имени И.И. Иванова" | Способ получения микрокапсул водорастворимых препаратов пестицидов |
US10011681B2 (en) | 2013-04-11 | 2018-07-03 | Mitsui Chemicals, Inc. | Process for producing a lactic acid-glycolic acid copolymer or a salt thereof |
RU2537173C1 (ru) * | 2013-05-24 | 2014-12-27 | Александр Александрович Кролевец | Способ получения микрокапсул гетероциклических соединений триазинового ряда |
RU2537248C1 (ru) * | 2013-05-24 | 2014-12-27 | Екатерина Евгеньевна Быковская | Способ получения микрокапсул гетероциклических соединений триазинового ряда |
JP6564369B2 (ja) | 2013-12-09 | 2019-08-21 | デュレクト コーポレイション | 薬学的活性剤複合体、ポリマー複合体、ならびにこれらを伴う組成物及び方法 |
CN106456704A (zh) | 2014-04-16 | 2017-02-22 | Veyx-药物有限公司 | 兽药组合物和其应用 |
AR101476A1 (es) | 2014-08-07 | 2016-12-21 | Acerta Pharma Bv | Métodos para tratar cánceres, enfermedades inmunes y autoinmunes, y enfermedades inflamatorias en base a la tasa de ocupación de la tirosin quinasa de bruton (btk) y a la tasa de resíntesis de la tirosin quinasa de bruton (btk) |
CN104224731A (zh) * | 2014-09-11 | 2014-12-24 | 北京天晟泰丰医药科技有限公司 | 一种不含致敏性辅料的九肽微球的制备方法 |
JP5938762B1 (ja) * | 2015-09-01 | 2016-06-22 | 日揮株式会社 | マイクロカプセル製剤及びその製造方法 |
CN110856690A (zh) * | 2018-08-22 | 2020-03-03 | 深圳善康医疗健康产业有限公司 | 一种植入剂包膜及干燥装置 |
WO2021234731A1 (en) * | 2020-05-18 | 2021-11-25 | Dr Reddy's Institute Of Life Sciences | Sustained release compositions |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60100516A (ja) | 1983-11-04 | 1985-06-04 | Takeda Chem Ind Ltd | 徐放型マイクロカプセルの製造法 |
JPH0678425B2 (ja) | 1984-07-06 | 1994-10-05 | 和光純薬工業株式会社 | 重合体の新規製造法 |
CA1256638A (en) * | 1984-07-06 | 1989-06-27 | Motoaki Tanaka | Polymer and its production |
JPH0720859B2 (ja) | 1985-02-07 | 1995-03-08 | 武田薬品工業株式会社 | マイクロカプセルの製造法 |
DE3678308D1 (de) | 1985-02-07 | 1991-05-02 | Takeda Chemical Industries Ltd | Verfahren zur herstellung von mikrokapseln. |
JP2551756B2 (ja) | 1985-05-07 | 1996-11-06 | 武田薬品工業株式会社 | ポリオキシカルボン酸エステルおよびその製造法 |
US5110904A (en) | 1989-08-07 | 1992-05-05 | Abbott Laboratories | Lhrh analogs |
CA1339679C (en) | 1988-02-10 | 1998-02-17 | Tap Pharmaceuticals Inc. | Reduced size lhrh analogs |
JP3200706B2 (ja) | 1990-04-13 | 2001-08-20 | 武田薬品工業株式会社 | 生体内分解型高分子重合物 |
ATE168391T1 (de) * | 1990-04-13 | 1998-08-15 | Takeda Chemical Industries Ltd | Biologisch abbaubare hochmolekulare polymere, ihre herstellung und ihre verwendung |
DE69220317T2 (de) | 1991-10-01 | 1997-10-16 | Takeda Chemical Industries Ltd | Mikropartikeln-Zusammenfassung zur verlängerten Freigabe und Herstellung derselbe |
JP3277342B2 (ja) | 1992-09-02 | 2002-04-22 | 武田薬品工業株式会社 | 徐放性マイクロカプセルの製造法 |
TW333456B (en) | 1992-12-07 | 1998-06-11 | Takeda Pharm Ind Co Ltd | A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide. |
JP3761594B2 (ja) * | 1993-07-05 | 2006-03-29 | 武田薬品工業株式会社 | 徐放性製剤の製造法 |
NZ260909A (en) * | 1993-07-05 | 1995-04-27 | Takeda Chemical Industries Ltd | Production of sustained release preparation by allowing a water-soluble polypeptide to permeate into a biodegradable matrix in an aqueous solution |
JPH08259460A (ja) | 1995-01-23 | 1996-10-08 | Takeda Chem Ind Ltd | 徐放性製剤の製造法 |
CA2192782C (en) * | 1995-12-15 | 2008-10-14 | Nobuyuki Takechi | Production of microspheres |
TR200002059T2 (tr) | 1998-01-16 | 2001-01-22 | Takeda Chemical Industries, Ltd. | Devamlı salınan bileşim, üretim yöntemi ve kullanımı. |
JPH11269094A (ja) | 1998-01-16 | 1999-10-05 | Takeda Chem Ind Ltd | 徐放性組成物、その製造法および用途 |
ATE289205T1 (de) * | 1998-12-15 | 2005-03-15 | Takeda Pharmaceutical | Verfahren zur herstellung biologisch-abbaubarer polyester |
JP3716146B2 (ja) * | 1998-12-15 | 2005-11-16 | 武田薬品工業株式会社 | ポリマーの製造方法 |
JP2002114667A (ja) | 2000-10-11 | 2002-04-16 | Ltt Institute Co Ltd | 徐放性製剤用組成物、その製造法および徐放性マイクロカプセル製剤 |
TWI332407B (en) * | 2001-06-29 | 2010-11-01 | Takeda Chemical Industries Ltd | Controlled release composition and method of producting the same |
ES2605402T3 (es) * | 2002-06-25 | 2017-03-14 | Takeda Pharmaceutical Company Limited | Procedimiento para producir una composición de liberación sostenida |
-
2002
- 2002-06-25 TW TW091113853A patent/TWI225416B/zh not_active IP Right Cessation
- 2002-06-26 AR ARP020102405A patent/AR034640A1/es not_active Application Discontinuation
- 2002-06-27 PE PE2002000577A patent/PE20030069A1/es not_active Application Discontinuation
- 2002-06-27 MY MYPI20022432A patent/MY139606A/en unknown
- 2002-06-28 BR BR0210572-1A patent/BR0210572A/pt not_active Application Discontinuation
- 2002-06-28 AU AU2002311630A patent/AU2002311630B2/en not_active Expired
- 2002-06-28 MX MXPA03011440A patent/MXPA03011440A/es active IP Right Grant
- 2002-06-28 SI SI200230837T patent/SI1399133T2/sl unknown
- 2002-06-28 SK SK1561-2003A patent/SK287568B6/sk unknown
- 2002-06-28 IL IL15906002A patent/IL159060A0/xx active IP Right Grant
- 2002-06-28 US US10/479,516 patent/US20040241229A1/en not_active Abandoned
- 2002-06-28 KR KR1020097017748A patent/KR20090096755A/ko not_active Application Discontinuation
- 2002-06-28 CZ CZ2003-3492A patent/CZ306388B6/cs not_active IP Right Cessation
- 2002-06-28 KR KR1020097017747A patent/KR100988178B1/ko active IP Right Grant
- 2002-06-28 RU RU2004102503/15A patent/RU2297240C2/ru active
- 2002-06-28 AT AT02738837T patent/ATE429903T1/de active
- 2002-06-28 EP EP09155256A patent/EP2108363A1/en not_active Withdrawn
- 2002-06-28 WO PCT/JP2002/006526 patent/WO2003002091A2/en active Application Filing
- 2002-06-28 DK DK02738837.0T patent/DK1399133T4/da active
- 2002-06-28 HU HU0400382A patent/HU230152B1/hu unknown
- 2002-06-28 PT PT02738837T patent/PT1399133E/pt unknown
- 2002-06-28 PL PL367491A patent/PL212531B1/pl not_active IP Right Cessation
- 2002-06-28 EP EP02738837A patent/EP1399133B2/en not_active Expired - Lifetime
- 2002-06-28 DE DE60232147T patent/DE60232147D1/de not_active Expired - Lifetime
- 2002-06-28 CN CN028130413A patent/CN1535141B/zh not_active Expired - Lifetime
- 2002-06-28 NZ NZ529968A patent/NZ529968A/en not_active IP Right Cessation
- 2002-06-28 ES ES02738837T patent/ES2324156T5/es not_active Expired - Lifetime
- 2002-06-28 KR KR10-2003-7017111A patent/KR20040018401A/ko active Search and Examination
- 2002-06-28 CA CA2451718A patent/CA2451718C/en not_active Expired - Fee Related
-
2003
- 2003-11-25 ZA ZA2003/09153A patent/ZA200309153B/en unknown
- 2003-12-19 NO NO20035737A patent/NO333531B1/no not_active IP Right Cessation
- 2003-12-22 CO CO03111730A patent/CO5540368A2/es not_active Application Discontinuation
-
2004
- 2004-07-05 HK HK04104826.8A patent/HK1061802A1/xx not_active IP Right Cessation
-
2006
- 2006-12-05 RU RU2006143104/15A patent/RU2434644C2/ru active
-
2007
- 2007-12-19 US US11/960,114 patent/US8258252B2/en not_active Expired - Lifetime
-
2009
- 2009-07-29 CY CY20091100808T patent/CY1109272T1/el unknown
-
2010
- 2010-08-11 JP JP2010180145A patent/JP5491318B2/ja not_active Expired - Lifetime
-
2012
- 2012-02-15 JP JP2012030788A patent/JP5860300B2/ja not_active Expired - Lifetime
- 2012-08-02 US US13/564,928 patent/US20120295848A1/en not_active Abandoned
-
2014
- 2014-09-10 JP JP2014184482A patent/JP5931147B2/ja not_active Expired - Lifetime
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