HUP0500382A2 - Elnyújtott hatóanyag-leadású, trimetazidine-hidroklorid mikrogyöngyöket tartalmazó gyógyszerkészítmények és eljárás előállításukra - Google Patents

Elnyújtott hatóanyag-leadású, trimetazidine-hidroklorid mikrogyöngyöket tartalmazó gyógyszerkészítmények és eljárás előállításukra

Info

Publication number
HUP0500382A2
HUP0500382A2 HU0500382A HUP0500382A HUP0500382A2 HU P0500382 A2 HUP0500382 A2 HU P0500382A2 HU 0500382 A HU0500382 A HU 0500382A HU P0500382 A HUP0500382 A HU P0500382A HU P0500382 A2 HUP0500382 A2 HU P0500382A2
Authority
HU
Hungary
Prior art keywords
pharmaceutical compositions
producing
sustained release
compositions containing
release pharmaceutical
Prior art date
Application number
HU0500382A
Other languages
English (en)
Inventor
Amit Krishna Antarkar
Rajendra Ghanshamlal Lala
Gaurang Hasmukhlal Thanawala
Maya Janak Shah
Janak Ramanlal Shah
Original Assignee
Themis Laboratories Private Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Themis Laboratories Private Limited filed Critical Themis Laboratories Private Limited
Publication of HUP0500382A2 publication Critical patent/HUP0500382A2/hu
Publication of HUP0500382A3 publication Critical patent/HUP0500382A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány készítményekre és gyógyszerkészítmények előállításáraszolgáló eljárásra vonatkozik mikrogyöngyök formájában, amelyektrimetazidine-dihidrokloridot tartalmaznak, és polimer membránnalvannak bevonva, amellyel a hatóanyag felszabadulásának jellemzői úgyszabályozhatók, hogy lehetővé tegyék dózisegységenként 60 mgtrimetazidine-dihidroklorid <napi egyszeri< adagolását. A trimetazidinismert antianginás hatású vegyület. Ó
HU0500382A 2001-11-21 2002-11-20 Sustained release pharmaceutical compositions containing microbeads of trimetazidine dihydrochloride and process for producing them HUP0500382A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1106MU2001 2001-11-21
PCT/IN2002/000223 WO2003043610A2 (en) 2001-11-21 2002-11-20 A process for manufacture of a sustained release composition containing microbe

Publications (2)

Publication Number Publication Date
HUP0500382A2 true HUP0500382A2 (hu) 2005-07-28
HUP0500382A3 HUP0500382A3 (en) 2008-03-28

Family

ID=11097321

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0500382A HUP0500382A3 (en) 2001-11-21 2002-11-20 Sustained release pharmaceutical compositions containing microbeads of trimetazidine dihydrochloride and process for producing them

Country Status (4)

Country Link
EP (1) EP1448173A2 (hu)
AU (1) AU2002356425A1 (hu)
HU (1) HUP0500382A3 (hu)
WO (1) WO2003043610A2 (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2885807B1 (fr) * 2005-05-18 2008-05-16 Mg Pharma Composition pharmaceutique solide a liberation prolongee de 1-(2,3,4-trimethoxybenzyl) piperazine, et procede de preparation
WO2009034541A2 (en) 2007-09-11 2009-03-19 Ranbaxy Laboratories Limited Controlled release pharmaceutical dosage forms of trimetazidine
TR201001902A2 (tr) 2010-03-12 2011-04-21 Ali̇ Rai̇f İlaç Sanayi̇ Ve Ti̇caret A.Ş. Uzatılmış salınımlı trimetazidin tablet
ES2508490T3 (es) 2010-05-04 2014-10-16 Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi Formulación de trimetazidina con diferentes perfiles de liberación
CN102133195A (zh) * 2011-03-17 2011-07-27 王国栋 盐酸曲美他嗪的缓控释微丸及其制备方法
FR2986431B1 (fr) * 2012-02-03 2017-03-17 Servier Lab Composition pharmaceutique a liberation prolongee de trimetazidine, son procede de fabrication et son utilisation dans des traitements therapeutiques

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2717687B1 (fr) * 1994-03-24 1996-06-14 Adir Compositions pharmaceutiques permettant la libération prolongée de trimétazidine après administration par voie orale.

Also Published As

Publication number Publication date
AU2002356425A1 (en) 2003-06-10
HUP0500382A3 (en) 2008-03-28
WO2003043610A2 (en) 2003-05-30
WO2003043610A3 (en) 2003-08-21
EP1448173A2 (en) 2004-08-25
AU2002356425A8 (en) 2003-06-10

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees