ATE331525T1 - Salzformarme polyallylamine - Google Patents

Salzformarme polyallylamine

Info

Publication number
ATE331525T1
ATE331525T1 AT02721716T AT02721716T ATE331525T1 AT E331525 T1 ATE331525 T1 AT E331525T1 AT 02721716 T AT02721716 T AT 02721716T AT 02721716 T AT02721716 T AT 02721716T AT E331525 T1 ATE331525 T1 AT E331525T1
Authority
AT
Austria
Prior art keywords
polyallylamines
salt form
low salt
polymer
diluent
Prior art date
Application number
AT02721716T
Other languages
English (en)
Inventor
John S Petersen
Steven Keith Burke
Stephen Randall Holmes-Farley
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Application granted granted Critical
Publication of ATE331525T1 publication Critical patent/ATE331525T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT02721716T 2001-04-18 2002-04-10 Salzformarme polyallylamine ATE331525T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28444501P 2001-04-18 2001-04-18

Publications (1)

Publication Number Publication Date
ATE331525T1 true ATE331525T1 (de) 2006-07-15

Family

ID=23090248

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02721716T ATE331525T1 (de) 2001-04-18 2002-04-10 Salzformarme polyallylamine

Country Status (16)

Country Link
US (2) US7541024B2 (de)
EP (1) EP1379258B1 (de)
JP (2) JP5170932B2 (de)
KR (1) KR20040018357A (de)
CN (1) CN1290515C (de)
AT (1) ATE331525T1 (de)
AU (1) AU2002252632B2 (de)
BR (1) BR0209020A (de)
CA (1) CA2444587C (de)
DE (1) DE60212819T2 (de)
ES (1) ES2268013T3 (de)
HK (1) HK1058620A1 (de)
MX (1) MXPA03009572A (de)
NZ (1) NZ528829A (de)
WO (1) WO2002085378A1 (de)
ZA (2) ZA200308065B (de)

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US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
WO2004037274A1 (en) * 2002-10-22 2004-05-06 Genzyme Corporation Amine polymers for promoting bone formation
AU2003263010A1 (en) * 2003-09-02 2005-04-21 Genzyme Corporation Method for reducing vascular inflammation
ES2453048T3 (es) 2004-03-30 2014-04-03 Relypsa, Inc. Polímeros de unión de ión y usos de los mismos
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
US8986669B2 (en) 2005-09-02 2015-03-24 Genzyme Corporation Method for removing phosphate and polymer used therefore
CN103027896B (zh) 2005-09-15 2016-01-20 基酶有限公司 胺聚合物的小袋制剂
US20100135950A1 (en) * 2006-07-05 2010-06-03 Genzyme Corporation Iron(II)-Containing Treatments for Hyperphosphatemia
WO2008042222A2 (en) 2006-09-29 2008-04-10 Genzyme Corporation Amide dendrimer compositions
US8163799B2 (en) 2006-12-14 2012-04-24 Genzyme Corporation Amido-amine polymer compositions
EP2016947A1 (de) 2007-07-17 2009-01-21 Chemo Ibérica, S.A. Neuartiges Verfahren zur Herstellung vernetzter Poly(allylamin-)Polymere in einem einzigen Schritt
WO2009125433A2 (en) * 2008-04-08 2009-10-15 Usv Limited Process for preparation of amine polymer salt
US8404784B2 (en) * 2008-12-03 2013-03-26 Navinta Llc Manufacturing process of making polymeric amine salts
AU2010261339A1 (en) * 2009-06-16 2012-01-19 Watson Pharma Private Limited Processes for the preparation of sevelamer carbonate
BR112012021444A2 (pt) * 2010-02-24 2016-05-31 Relypsa Inc polímero de amina reticulado, composição farmacêutica, método de redução do colesterol ldl sérico em um indivíduo, métodos para tratar doença, de remoção de sais biliares de um indivíduo, e para melhorar o controle glicêmico em um indivíduo, e, processo para preparar o polímero de aminas.
RU2728778C2 (ru) 2013-06-05 2020-07-31 Трисида, Инк. Протон-связывающие полимеры для перорального введения
JP6903576B2 (ja) 2014-12-10 2021-07-14 トリシダ・インコーポレイテッドＴｒｉｃｉｄａ， Ｉｎｃ． 経口投与用プロトン結合ポリマー
MX2018013476A (es) 2016-05-06 2019-03-28 Tricida Inc Composiciones para tratar trastornos acido-base.
AU2017388956A1 (en) 2016-12-28 2019-07-11 Fujifilm Corporation Emulsion of nitrogen atom-containing polymer or salt thereof, production method therefor, and production method for particles
WO2019078198A1 (ja) 2017-10-16 2019-04-25 富士フイルム株式会社 高リン血症治療剤および粒子
EP3698799B1 (de) 2017-10-16 2022-01-26 FUJIFILM Corporation Mittel zur behandlung von hyperphosphatämie
CA3080651A1 (en) 2017-11-03 2019-05-09 Tricida, Inc. Compositions for and method of treating acid-base disorders
CN110753217B (zh) * 2019-10-28 2022-03-01 黑芝麻智能科技(上海)有限公司 色彩平衡方法和装置、车载设备以及存储介质
US11572355B2 (en) * 2020-07-16 2023-02-07 The Board Of Trustees Of The University Of Alabama Methods for synthesizing vinylidenes and alkenes
CN112047854B (zh) * 2020-10-20 2021-07-02 中国科学院长春应用化学研究所 一种n-乙烯基烷基酰胺的制备方法
EP4164659B1 (de) * 2021-08-24 2024-03-27 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Polymere, zusammensetzungen und verfahren zur behandlung von hyperurikämie
CN116018146A (zh) * 2021-08-24 2023-04-25 中美华世通生物医药科技(武汉)股份有限公司 用于治疗高尿酸血症的聚合物、组合物和方法

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US4222921A (en) * 1978-06-19 1980-09-16 Monsanto Company Polyamine/epihalohydrin reaction products
JPS6090243A (ja) * 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
US4528347A (en) * 1983-11-10 1985-07-09 501 Nitto Boseki, Co. Ltd Process for producing polymers of monoallylamine
US4614593A (en) * 1985-03-28 1986-09-30 Ethyl Corporation Demulsification of oil-in-water emulsions
IE914179A1 (en) * 1990-12-07 1992-06-17 Ici Plc Nitrogen derivatives
US5487888A (en) * 1993-05-20 1996-01-30 Geltex, Inc. Iron-binding polymers for oral administration
US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
US5624963A (en) * 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
US5618530A (en) * 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5703188A (en) * 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5667775A (en) * 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5496545A (en) * 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
TW474813B (en) * 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
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US6203785B1 (en) * 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
US5925379A (en) * 1997-03-27 1999-07-20 Geltex Pharmaceuticals, Inc. Interpenetrating polymer networks for sequestration of bile acids
JP2003183168A (ja) * 1997-04-04 2003-07-03 Chugai Pharmaceut Co Ltd リン酸結合性ポリマー含有製剤
TW592727B (en) 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
US6423754B1 (en) * 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
US5985938A (en) * 1997-11-05 1999-11-16 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US6083497A (en) * 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
WO1999040990A1 (en) 1998-02-17 1999-08-19 University Of Maryland Anion binding polymers and the use thereof
TW568788B (en) * 1998-10-12 2004-01-01 Chugai Pharmaceutical Co Ltd Polymer combining with phosphoric acid and preparation containing the same
US6180754B1 (en) * 1999-09-03 2001-01-30 The Dow Chemical Company Process for producing cross-linked polyallylamine polymer
US6733780B1 (en) * 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core

Also Published As

Publication number Publication date
DE60212819D1 (de) 2006-08-10
CN1503676A (zh) 2004-06-09
DE60212819T2 (de) 2006-11-23
CA2444587C (en) 2008-10-21
NZ528829A (en) 2006-06-30
ZA200308065B (en) 2004-09-14
US7541024B2 (en) 2009-06-02
US8377428B2 (en) 2013-02-19
US20100068167A1 (en) 2010-03-18
CA2444587A1 (en) 2002-10-31
EP1379258B1 (de) 2006-06-28
JP2004526777A (ja) 2004-09-02
CN1290515C (zh) 2006-12-20
KR20040018357A (ko) 2004-03-03
JP5243466B2 (ja) 2013-07-24
ZA200308063B (en) 2005-01-17
MXPA03009572A (es) 2004-02-12
US20020159968A1 (en) 2002-10-31
JP5170932B2 (ja) 2013-03-27
JP2010111704A (ja) 2010-05-20
WO2002085378A1 (en) 2002-10-31
HK1058620A1 (en) 2004-05-28
AU2002252632B2 (en) 2004-09-23
ES2268013T3 (es) 2007-03-16
EP1379258A1 (de) 2004-01-14
BR0209020A (pt) 2004-08-10

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