DE60212819D1 - Salzformarme polyallylamine - Google Patents

Salzformarme polyallylamine

Info

Publication number
DE60212819D1
DE60212819D1 DE60212819T DE60212819T DE60212819D1 DE 60212819 D1 DE60212819 D1 DE 60212819D1 DE 60212819 T DE60212819 T DE 60212819T DE 60212819 T DE60212819 T DE 60212819T DE 60212819 D1 DE60212819 D1 DE 60212819D1
Authority
DE
Germany
Prior art keywords
polyallylamine
salt form
polymer
diluent
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60212819T
Other languages
English (en)
Other versions
DE60212819T2 (de
Inventor
S Petersen
Keith Burke
Randall Holmes-Farley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genzyme Corp
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of DE60212819D1 publication Critical patent/DE60212819D1/de
Application granted granted Critical
Publication of DE60212819T2 publication Critical patent/DE60212819T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE60212819T 2001-04-18 2002-04-10 Salzformarme polyallylamine Expired - Lifetime DE60212819T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28444501P 2001-04-18 2001-04-18
US284445P 2001-04-18
PCT/US2002/011408 WO2002085378A1 (en) 2001-04-18 2002-04-10 Low salt forms of polyallylamine

Publications (2)

Publication Number Publication Date
DE60212819D1 true DE60212819D1 (de) 2006-08-10
DE60212819T2 DE60212819T2 (de) 2006-11-23

Family

ID=23090248

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60212819T Expired - Lifetime DE60212819T2 (de) 2001-04-18 2002-04-10 Salzformarme polyallylamine

Country Status (16)

Country Link
US (2) US7541024B2 (de)
EP (1) EP1379258B1 (de)
JP (2) JP5170932B2 (de)
KR (1) KR20040018357A (de)
CN (1) CN1290515C (de)
AT (1) ATE331525T1 (de)
AU (1) AU2002252632B2 (de)
BR (1) BR0209020A (de)
CA (1) CA2444587C (de)
DE (1) DE60212819T2 (de)
ES (1) ES2268013T3 (de)
HK (1) HK1058620A1 (de)
MX (1) MXPA03009572A (de)
NZ (1) NZ528829A (de)
WO (1) WO2002085378A1 (de)
ZA (2) ZA200308063B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
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US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
AU2003282867A1 (en) * 2002-10-22 2004-05-13 Genzyme Corporation Amine polymers for promoting bone formation
AU2003263010A1 (en) * 2003-09-02 2005-04-21 Genzyme Corporation Method for reducing vascular inflammation
GB2456256B (en) 2004-03-30 2009-08-26 Relypsa Inc Ion binding compositions
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
JP2009507019A (ja) 2005-09-02 2009-02-19 ジェンザイム・コーポレーション リン酸塩を除去する方法およびそれに使用される重合体
DK1924246T3 (en) 2005-09-15 2016-01-18 Genzyme Corp PORTION LETTER DEFINITION OF amine polymers
EP2043627A2 (de) * 2006-07-05 2009-04-08 Genzyme Corporation Eisen(ii)-haltige behandlungen für hyperphosphatämie
EP2066293A2 (de) 2006-09-29 2009-06-10 Genzyme Corporation Amid-dendrimer-zusammensetzungen
BRPI0720234A2 (pt) 2006-12-14 2013-12-24 Genzyme Corp Composição farmacêutica
EP2016947A1 (de) 2007-07-17 2009-01-21 Chemo Ibérica, S.A. Neuartiges Verfahren zur Herstellung vernetzter Poly(allylamin-)Polymere in einem einzigen Schritt
RU2010145166A (ru) * 2008-04-08 2012-05-20 Юсв Лимитед (In) Способ получения соли аминополимера
US8404784B2 (en) * 2008-12-03 2013-03-26 Navinta Llc Manufacturing process of making polymeric amine salts
CA2765370A1 (en) * 2009-06-16 2010-12-23 Watson Pharma Private Limited Processes for the preparation of sevelamer carbonate
AU2011220742B2 (en) * 2010-02-24 2016-02-25 Relypsa, Inc. Crosslinked polyvinylamine, polyallylamine, and polyethyleneimine for use as bile acid sequestrants
LT3003327T (lt) * 2013-06-05 2017-12-27 Tricida Inc. Protonus surišantys polimerai, skirti geriamajam vartojimui
ES2857177T3 (es) * 2014-12-10 2021-09-28 Tricida Inc Polímeros de unión de protones para administración oral
US20190209607A1 (en) 2016-05-06 2019-07-11 Tricida, Inc. Compositions for treating acid-base disorders
WO2018124264A1 (ja) 2016-12-28 2018-07-05 富士フイルム株式会社 窒素原子含有ポリマー又はその塩の乳化液、その製造方法、及び粒子の製造方法
AU2018352766B2 (en) 2017-10-16 2021-09-23 Fujifilm Corporation Hyperphosphatemia treatment agent, and particles
EP3698799B1 (de) 2017-10-16 2022-01-26 FUJIFILM Corporation Mittel zur behandlung von hyperphosphatämie
US11266684B2 (en) 2017-11-03 2022-03-08 Tricida, Inc. Compositions for and method of treating acid-base disorders
CN110753217B (zh) * 2019-10-28 2022-03-01 黑芝麻智能科技(上海)有限公司 色彩平衡方法和装置、车载设备以及存储介质
US11572355B2 (en) * 2020-07-16 2023-02-07 The Board Of Trustees Of The University Of Alabama Methods for synthesizing vinylidenes and alkenes
CN112047854B (zh) * 2020-10-20 2021-07-02 中国科学院长春应用化学研究所 一种n-乙烯基烷基酰胺的制备方法
CN116018147A (zh) * 2021-08-24 2023-04-25 中美华世通生物医药科技(武汉)股份有限公司 用于治疗高尿酸血症的聚合物、组合物和方法
EP4161534A1 (de) * 2021-08-24 2023-04-12 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Polymere, zusammensetzungen und verfahren zur behandlung von hyperurikämie

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4222921A (en) * 1978-06-19 1980-09-16 Monsanto Company Polyamine/epihalohydrin reaction products
JPS6090243A (ja) * 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
US4528347A (en) * 1983-11-10 1985-07-09 501 Nitto Boseki, Co. Ltd Process for producing polymers of monoallylamine
US4614593A (en) * 1985-03-28 1986-09-30 Ethyl Corporation Demulsification of oil-in-water emulsions
IE914179A1 (en) * 1990-12-07 1992-06-17 Ici Plc Nitrogen derivatives
US5487888A (en) * 1993-05-20 1996-01-30 Geltex, Inc. Iron-binding polymers for oral administration
US5703188A (en) * 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5618530A (en) * 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
US5624963A (en) * 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5496545A (en) * 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5667775A (en) * 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
TW474813B (en) * 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
WO1996021454A1 (en) * 1995-01-12 1996-07-18 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US6203785B1 (en) * 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
US5925379A (en) * 1997-03-27 1999-07-20 Geltex Pharmaceuticals, Inc. Interpenetrating polymer networks for sequestration of bile acids
TW592727B (en) 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
JP2003183168A (ja) * 1997-04-04 2003-07-03 Chugai Pharmaceut Co Ltd リン酸結合性ポリマー含有製剤
US6423754B1 (en) * 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
US5985938A (en) * 1997-11-05 1999-11-16 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US6083497A (en) * 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
WO1999040990A1 (en) 1998-02-17 1999-08-19 University Of Maryland Anion binding polymers and the use thereof
TW568788B (en) * 1998-10-12 2004-01-01 Chugai Pharmaceutical Co Ltd Polymer combining with phosphoric acid and preparation containing the same
US6180754B1 (en) * 1999-09-03 2001-01-30 The Dow Chemical Company Process for producing cross-linked polyallylamine polymer
US6733780B1 (en) * 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core

Also Published As

Publication number Publication date
BR0209020A (pt) 2004-08-10
ZA200308065B (en) 2004-09-14
KR20040018357A (ko) 2004-03-03
JP2010111704A (ja) 2010-05-20
JP5170932B2 (ja) 2013-03-27
NZ528829A (en) 2006-06-30
US7541024B2 (en) 2009-06-02
CN1503676A (zh) 2004-06-09
CA2444587A1 (en) 2002-10-31
ES2268013T3 (es) 2007-03-16
JP5243466B2 (ja) 2013-07-24
ZA200308063B (en) 2005-01-17
JP2004526777A (ja) 2004-09-02
EP1379258B1 (de) 2006-06-28
HK1058620A1 (en) 2004-05-28
ATE331525T1 (de) 2006-07-15
US20020159968A1 (en) 2002-10-31
MXPA03009572A (es) 2004-02-12
EP1379258A1 (de) 2004-01-14
AU2002252632B2 (en) 2004-09-23
CN1290515C (zh) 2006-12-20
US20100068167A1 (en) 2010-03-18
CA2444587C (en) 2008-10-21
US8377428B2 (en) 2013-02-19
WO2002085378A1 (en) 2002-10-31
DE60212819T2 (de) 2006-11-23

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Legal Events

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