ZA200308063B - Method of lowering serum glucose. - Google Patents

Method of lowering serum glucose. Download PDF

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Publication number
ZA200308063B
ZA200308063B ZA200308063A ZA200308063A ZA200308063B ZA 200308063 B ZA200308063 B ZA 200308063B ZA 200308063 A ZA200308063 A ZA 200308063A ZA 200308063 A ZA200308063 A ZA 200308063A ZA 200308063 B ZA200308063 B ZA 200308063B
Authority
ZA
South Africa
Prior art keywords
polymer
solid
water
stirred
subject
Prior art date
Application number
ZA200308063A
Other languages
English (en)
Inventor
Steven K Burke
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of ZA200308063B publication Critical patent/ZA200308063B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA200308063A 2001-04-18 2003-10-16 Method of lowering serum glucose. ZA200308063B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28444501P 2001-04-18 2001-04-18

Publications (1)

Publication Number Publication Date
ZA200308063B true ZA200308063B (en) 2005-01-17

Family

ID=23090248

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA200308063A ZA200308063B (en) 2001-04-18 2003-10-16 Method of lowering serum glucose.
ZA200308065A ZA200308065B (en) 2001-04-18 2003-10-16 Low salt forms of polyallylamine.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA200308065A ZA200308065B (en) 2001-04-18 2003-10-16 Low salt forms of polyallylamine.

Country Status (16)

Country Link
US (2) US7541024B2 (de)
EP (1) EP1379258B1 (de)
JP (2) JP5170932B2 (de)
KR (1) KR20040018357A (de)
CN (1) CN1290515C (de)
AT (1) ATE331525T1 (de)
AU (1) AU2002252632B2 (de)
BR (1) BR0209020A (de)
CA (1) CA2444587C (de)
DE (1) DE60212819T2 (de)
ES (1) ES2268013T3 (de)
HK (1) HK1058620A1 (de)
MX (1) MXPA03009572A (de)
NZ (1) NZ528829A (de)
WO (1) WO2002085378A1 (de)
ZA (2) ZA200308063B (de)

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US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
AU2003282867A1 (en) * 2002-10-22 2004-05-13 Genzyme Corporation Amine polymers for promoting bone formation
AU2003263010A1 (en) * 2003-09-02 2005-04-21 Genzyme Corporation Method for reducing vascular inflammation
GB2456256B (en) 2004-03-30 2009-08-26 Relypsa Inc Ion binding compositions
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
JP2009507019A (ja) 2005-09-02 2009-02-19 ジェンザイム・コーポレーション リン酸塩を除去する方法およびそれに使用される重合体
DK1924246T3 (en) 2005-09-15 2016-01-18 Genzyme Corp PORTION LETTER DEFINITION OF amine polymers
EP2043627A2 (de) * 2006-07-05 2009-04-08 Genzyme Corporation Eisen(ii)-haltige behandlungen für hyperphosphatämie
EP2066293A2 (de) 2006-09-29 2009-06-10 Genzyme Corporation Amid-dendrimer-zusammensetzungen
BRPI0720234A2 (pt) 2006-12-14 2013-12-24 Genzyme Corp Composição farmacêutica
EP2016947A1 (de) 2007-07-17 2009-01-21 Chemo Ibérica, S.A. Neuartiges Verfahren zur Herstellung vernetzter Poly(allylamin-)Polymere in einem einzigen Schritt
RU2010145166A (ru) * 2008-04-08 2012-05-20 Юсв Лимитед (In) Способ получения соли аминополимера
US8404784B2 (en) * 2008-12-03 2013-03-26 Navinta Llc Manufacturing process of making polymeric amine salts
CA2765370A1 (en) * 2009-06-16 2010-12-23 Watson Pharma Private Limited Processes for the preparation of sevelamer carbonate
AU2011220742B2 (en) * 2010-02-24 2016-02-25 Relypsa, Inc. Crosslinked polyvinylamine, polyallylamine, and polyethyleneimine for use as bile acid sequestrants
LT3003327T (lt) * 2013-06-05 2017-12-27 Tricida Inc. Protonus surišantys polimerai, skirti geriamajam vartojimui
ES2857177T3 (es) * 2014-12-10 2021-09-28 Tricida Inc Polímeros de unión de protones para administración oral
US20190209607A1 (en) 2016-05-06 2019-07-11 Tricida, Inc. Compositions for treating acid-base disorders
WO2018124264A1 (ja) 2016-12-28 2018-07-05 富士フイルム株式会社 窒素原子含有ポリマー又はその塩の乳化液、その製造方法、及び粒子の製造方法
AU2018352766B2 (en) 2017-10-16 2021-09-23 Fujifilm Corporation Hyperphosphatemia treatment agent, and particles
EP3698799B1 (de) 2017-10-16 2022-01-26 FUJIFILM Corporation Mittel zur behandlung von hyperphosphatämie
US11266684B2 (en) 2017-11-03 2022-03-08 Tricida, Inc. Compositions for and method of treating acid-base disorders
CN110753217B (zh) * 2019-10-28 2022-03-01 黑芝麻智能科技(上海)有限公司 色彩平衡方法和装置、车载设备以及存储介质
US11572355B2 (en) * 2020-07-16 2023-02-07 The Board Of Trustees Of The University Of Alabama Methods for synthesizing vinylidenes and alkenes
CN112047854B (zh) * 2020-10-20 2021-07-02 中国科学院长春应用化学研究所 一种n-乙烯基烷基酰胺的制备方法
CN116018147A (zh) * 2021-08-24 2023-04-25 中美华世通生物医药科技(武汉)股份有限公司 用于治疗高尿酸血症的聚合物、组合物和方法
EP4161534A1 (de) * 2021-08-24 2023-04-12 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Polymere, zusammensetzungen und verfahren zur behandlung von hyperurikämie

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US4222921A (en) * 1978-06-19 1980-09-16 Monsanto Company Polyamine/epihalohydrin reaction products
JPS6090243A (ja) * 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
US4528347A (en) * 1983-11-10 1985-07-09 501 Nitto Boseki, Co. Ltd Process for producing polymers of monoallylamine
US4614593A (en) * 1985-03-28 1986-09-30 Ethyl Corporation Demulsification of oil-in-water emulsions
IE914179A1 (en) * 1990-12-07 1992-06-17 Ici Plc Nitrogen derivatives
US5487888A (en) * 1993-05-20 1996-01-30 Geltex, Inc. Iron-binding polymers for oral administration
US5703188A (en) * 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5618530A (en) * 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
US5624963A (en) * 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5496545A (en) * 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
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US6203785B1 (en) * 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
US5925379A (en) * 1997-03-27 1999-07-20 Geltex Pharmaceuticals, Inc. Interpenetrating polymer networks for sequestration of bile acids
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US6423754B1 (en) * 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
US5985938A (en) * 1997-11-05 1999-11-16 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US6083497A (en) * 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
WO1999040990A1 (en) 1998-02-17 1999-08-19 University Of Maryland Anion binding polymers and the use thereof
TW568788B (en) * 1998-10-12 2004-01-01 Chugai Pharmaceutical Co Ltd Polymer combining with phosphoric acid and preparation containing the same
US6180754B1 (en) * 1999-09-03 2001-01-30 The Dow Chemical Company Process for producing cross-linked polyallylamine polymer
US6733780B1 (en) * 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core

Also Published As

Publication number Publication date
BR0209020A (pt) 2004-08-10
ZA200308065B (en) 2004-09-14
KR20040018357A (ko) 2004-03-03
JP2010111704A (ja) 2010-05-20
JP5170932B2 (ja) 2013-03-27
NZ528829A (en) 2006-06-30
US7541024B2 (en) 2009-06-02
CN1503676A (zh) 2004-06-09
CA2444587A1 (en) 2002-10-31
ES2268013T3 (es) 2007-03-16
JP5243466B2 (ja) 2013-07-24
JP2004526777A (ja) 2004-09-02
EP1379258B1 (de) 2006-06-28
HK1058620A1 (en) 2004-05-28
ATE331525T1 (de) 2006-07-15
US20020159968A1 (en) 2002-10-31
MXPA03009572A (es) 2004-02-12
EP1379258A1 (de) 2004-01-14
AU2002252632B2 (en) 2004-09-23
CN1290515C (zh) 2006-12-20
US20100068167A1 (en) 2010-03-18
CA2444587C (en) 2008-10-21
DE60212819D1 (de) 2006-08-10
US8377428B2 (en) 2013-02-19
WO2002085378A1 (en) 2002-10-31
DE60212819T2 (de) 2006-11-23

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