GR1003658B - Δισκιο μητρας που καθιστα δυνατη την παρατεταμενη απελευθερωση της τριμεταζιδινης μετα χορηγηση δια της στοματικης οδου - Google Patents

Δισκιο μητρας που καθιστα δυνατη την παρατεταμενη απελευθερωση της τριμεταζιδινης μετα χορηγηση δια της στοματικης οδου

Info

Publication number
GR1003658B
GR1003658B GR20000100433A GR2000100433A GR1003658B GR 1003658 B GR1003658 B GR 1003658B GR 20000100433 A GR20000100433 A GR 20000100433A GR 2000100433 A GR2000100433 A GR 2000100433A GR 1003658 B GR1003658 B GR 1003658B
Authority
GR
Greece
Prior art keywords
prolonged release
trimetazidine
administration
oral route
matrix tablet
Prior art date
Application number
GR20000100433A
Other languages
English (en)
Inventor
De Barochez Bruno Huet
Claude Dauphant
Patrick Wuthrich
Original Assignee
Adir Et Compagnie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9553398&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR1003658(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Adir Et Compagnie filed Critical Adir Et Compagnie
Publication of GR1003658B publication Critical patent/GR1003658B/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Η παρούσα εφεύρεση αφορά ένα δισκίο μήτρας που καθιστά δυνατή την παρατεταμένη απελευθέρωση τριμεταζιδίνης, ή ενός άλατος προσθήκης αυτής με ένα φαρμακευτικώς αποδεκτό οξύ μετά χορήγηση δια της οδού του στόματος, χαρακτηριζόμενο εκ του ότι η παρατεταμένη απελευθέρωση ελέγχεται δια χρησιμοποιήσεως ενός πολυμερούς παραγώγου κυτταρίνης.ΰ
GR20000100433A 1999-12-17 2000-12-15 Δισκιο μητρας που καθιστα δυνατη την παρατεταμενη απελευθερωση της τριμεταζιδινης μετα χορηγηση δια της στοματικης οδου GR1003658B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9915960A FR2802424B1 (fr) 1999-12-17 1999-12-17 Comprime matriciel permettant la liberation prolongee de trimetazidine apres administration par voie orale

Publications (1)

Publication Number Publication Date
GR1003658B true GR1003658B (el) 2001-09-05

Family

ID=9553398

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000100433A GR1003658B (el) 1999-12-17 2000-12-15 Δισκιο μητρας που καθιστα δυνατη την παρατεταμενη απελευθερωση της τριμεταζιδινης μετα χορηγηση δια της στοματικης οδου

Country Status (33)

Country Link
EP (1) EP1108424B2 (el)
JP (2) JP2001172181A (el)
KR (1) KR100456933B1 (el)
CN (1) CN1166408C (el)
AR (1) AR026968A1 (el)
AT (1) ATE296622T1 (el)
AU (1) AU780011B2 (el)
BG (1) BG65773B1 (el)
BR (1) BR0005915A (el)
CY (1) CY2347B1 (el)
CZ (1) CZ299461B6 (el)
DE (1) DE60020501T3 (el)
DK (1) DK1108424T4 (el)
EA (2) EA200501901A1 (el)
ES (2) ES2240033T5 (el)
FR (1) FR2802424B1 (el)
GE (1) GEP20053540B (el)
GR (1) GR1003658B (el)
HK (1) HK1036937A1 (el)
HU (1) HU226956B1 (el)
IE (1) IE20001017A1 (el)
IT (1) IT1317075B1 (el)
LU (1) LU90700B1 (el)
MX (1) MXPA00012462A (el)
NZ (1) NZ508912A (el)
OA (1) OA12121A (el)
PL (1) PL206994B1 (el)
PT (2) PT102542A (el)
SI (1) SI1108424T2 (el)
SK (1) SK286752B6 (el)
UA (1) UA80087C2 (el)
WO (1) WO2001043747A1 (el)
ZA (1) ZA200007548B (el)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE442852T1 (de) * 2000-10-05 2009-10-15 Usv Ltd Trimetazidine enthaltendes arzneimittel mit verzögerter wirkstoffabgabe und verfahren zur herstellung
KR101175816B1 (ko) * 2003-08-04 2012-08-24 교린 세이야꾸 가부시키 가이샤 경구 서방성 정제
SG126792A1 (en) * 2005-04-27 2006-11-29 Servier Lab Matrix tablet enabling the prolonged release of trimetazidine after administration by the oral route
FR2885807B1 (fr) * 2005-05-18 2008-05-16 Mg Pharma Composition pharmaceutique solide a liberation prolongee de 1-(2,3,4-trimethoxybenzyl) piperazine, et procede de preparation
CZ300307B6 (cs) * 2006-01-04 2009-04-15 Zentiva, A. S. Tableta s obsahem trimetazidinu nebo jeho farmakologicky akceptovatelné soli s modifikovaným uvolnováním
EA009776B1 (ru) * 2006-07-18 2008-04-28 Мераб Ревазович Кокеладзе Способ изготовления таблетированной лекарственной формы триметазидина дигидрохлорида и ее состав
EA009810B1 (ru) * 2006-12-26 2008-04-28 Закрытое Акционерное Общество "Канонфарма Продакшн" Матрица для изготовления таблетированной лекарственной формы и способ лечения
EP2200591A2 (en) * 2007-09-11 2010-06-30 Ranbaxy Laboratories Limited Controlled release pharmaceutical dosage forms of trimetazidine
WO2010084397A2 (en) 2009-01-20 2010-07-29 Micro Labs Limited Modified release solid pharmaceutical compositions of trimetazidine and process thereof
PL2391353T3 (pl) * 2009-01-30 2016-09-30 Kompozycje farmaceutyczne trimetazydyny
TR201001902A2 (tr) 2010-03-12 2011-04-21 Ali̇ Rai̇f İlaç Sanayi̇ Ve Ti̇caret A.Ş. Uzatılmış salınımlı trimetazidin tablet
RU2445958C2 (ru) * 2010-04-20 2012-03-27 Общество с ограниченной ответственностью "Озон" (ООО "Озон") Матричная таблетка с основой для пролонгированного высвобождения триметазидина и способ ее изготовления
EP2394644B1 (en) 2010-05-04 2014-07-09 Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi Trimetazidine Formulation With Different Release Profiles
EP2386302A1 (en) 2010-05-11 2011-11-16 Ranbaxy Laboratories Limited A controlled release pharmaceutical dosage form of trimetazidine and processes for the preparation thereof
EP2491930A1 (en) 2011-02-25 2012-08-29 Deva Holding Anonim Sirketi Pharmaceutical combination of betahistine and trimetazidine
FR2978916B1 (fr) * 2011-08-10 2013-07-26 Servier Lab Composition pharmaceutique solide pour administration buccale d'agomelatine
FR2986431B1 (fr) 2012-02-03 2017-03-17 Servier Lab Composition pharmaceutique a liberation prolongee de trimetazidine, son procede de fabrication et son utilisation dans des traitements therapeutiques
CN102824644B (zh) * 2012-09-13 2013-12-25 浙江诚意药业有限公司 使用羟丙基纤维素制备的高稳定性的缓释片
KR20160118733A (ko) 2015-04-03 2016-10-12 이인현 호스 권취용 호스 안내장치 및 이를 구비한 호스 권취기
CN109316455B (zh) * 2017-07-31 2021-05-25 北京福元医药股份有限公司 一种盐酸曲美他嗪缓释片
CN109908096A (zh) * 2017-12-12 2019-06-21 武汉武药科技有限公司 一种盐酸曲美他嗪缓释片及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2490963A1 (fr) * 1980-09-30 1982-04-02 Science Union & Cie Nouvelle composition therapeutique a action anti-ischemique contenant de la trimethoxy 2, 3, 4-benzyl 1-piperazine
JPS61212517A (ja) * 1985-03-18 1986-09-20 Nippon Chemiphar Co Ltd 持続性錠剤
US5334392A (en) * 1991-06-18 1994-08-02 Adir Et Compagnie Matrix tablet permitting the sustained release of indapamide after oral administration
EP0673649A1 (fr) * 1994-03-24 1995-09-27 Adir Et Compagnie Compositions pharmaceutiques permettant la libération prolongée de trimétazidine après administration par voie orale

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US4226849A (en) * 1979-06-14 1980-10-07 Forest Laboratories Inc. Sustained release therapeutic compositions
KR850006132A (ko) * 1984-02-29 1985-10-02 진 크라메르, 한스 루돌프 하우스 브로모크립틴 조성물
JPS61293931A (ja) * 1985-06-24 1986-12-24 Teijin Ltd 徐放性医薬品組成物
DE3676235D1 (de) * 1985-06-04 1991-01-31 Teijin Ltd Arzneizubereitung mit verzoegerter wirkstoffabgabe.
SE455836B (sv) * 1985-10-11 1988-08-15 Haessle Ab Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning
SE8601624D0 (sv) * 1986-04-11 1986-04-11 Haessle Ab New pharmaceutical preparations
FR2681324B1 (fr) * 1991-09-18 1993-10-29 Adir Cie Nouveaux derives de la trimetazidine, leur procede de preparation et les compositions pharmaceutiques les contenant.
KR940021051A (ko) * 1993-03-03 1994-10-17 손정삼 3단계 약물방출형 지속성 정제
RU2082400C1 (ru) * 1993-12-16 1997-06-27 Акционерное общество - Фармацевтическая фирма "Ник-Фарм" Способ получения нитроглицерина пролонгированного действия

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2490963A1 (fr) * 1980-09-30 1982-04-02 Science Union & Cie Nouvelle composition therapeutique a action anti-ischemique contenant de la trimethoxy 2, 3, 4-benzyl 1-piperazine
JPS61212517A (ja) * 1985-03-18 1986-09-20 Nippon Chemiphar Co Ltd 持続性錠剤
US5334392A (en) * 1991-06-18 1994-08-02 Adir Et Compagnie Matrix tablet permitting the sustained release of indapamide after oral administration
EP0673649A1 (fr) * 1994-03-24 1995-09-27 Adir Et Compagnie Compositions pharmaceutiques permettant la libération prolongée de trimétazidine après administration par voie orale

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 106, no. 8, 23 February 1987, Columbus, Ohio, US; abstract no. 55929, Y YOSHIYUKI, K SEIJI, Y HIRANOJO, O HEIICHI: "Long-lasting tablet formulations" XP002172370 *
DATABASE WPI Week 8644, Derwent World Patents Index; AN 1986-289031, XP002145828, "Sustained release tablets contg. water-soluble medicine - using ultramicropowder of enteric polymer base as matrix material" *

Also Published As

Publication number Publication date
SK8632002A3 (en) 2002-10-08
UA80087C2 (en) 2007-08-27
ITRM20000667A0 (it) 2000-12-14
EA200501901A1 (ru) 2006-06-30
MXPA00012462A (es) 2002-06-04
DK1108424T4 (da) 2013-12-16
ES2176106A1 (es) 2002-11-16
OA12121A (en) 2003-10-20
PT1108424E (pt) 2005-08-31
BG106927A (en) 2003-05-30
EP1108424B1 (fr) 2005-06-01
IT1317075B1 (it) 2003-05-26
EP1108424A1 (fr) 2001-06-20
DK1108424T3 (da) 2005-10-03
JP2007314578A (ja) 2007-12-06
IE20001017A1 (en) 2002-04-03
JP2001172181A (ja) 2001-06-26
SI1108424T1 (en) 2005-10-31
BG65773B1 (bg) 2009-11-30
PL344564A1 (en) 2001-06-18
EA008223B1 (ru) 2007-04-27
LU90700B1 (fr) 2007-12-03
WO2001043747A8 (fr) 2001-09-07
HU226956B1 (en) 2010-03-29
HK1036937A1 (en) 2002-01-25
ATE296622T1 (de) 2005-06-15
PT102542A (pt) 2001-06-29
HUP0004966A3 (en) 2008-04-28
CZ20022082A3 (cs) 2002-09-11
WO2001043747A1 (fr) 2001-06-21
EA200001201A3 (ru) 2001-10-22
CN1302663A (zh) 2001-07-11
BR0005915A (pt) 2001-10-02
FR2802424B1 (fr) 2002-02-15
ITRM20000667A1 (it) 2002-06-14
AR026968A1 (es) 2003-03-05
KR20010062478A (ko) 2001-07-07
PL206994B1 (pl) 2010-10-29
NZ508912A (en) 2002-04-26
ES2240033T5 (es) 2014-01-16
CY2347B1 (en) 2004-06-04
HU0004966D0 (el) 2001-02-28
EA200001201A2 (ru) 2001-08-27
SI1108424T2 (sl) 2014-02-28
HUP0004966A2 (en) 2002-06-29
EP1108424B2 (fr) 2013-09-04
ES2176106B1 (es) 2004-01-16
AU7228500A (en) 2001-06-21
DE60020501T3 (de) 2014-03-20
DE60020501T2 (de) 2006-04-27
ES2240033T3 (es) 2005-10-16
SK286752B6 (sk) 2009-04-06
KR100456933B1 (ko) 2004-11-10
GEP20053540B (en) 2005-06-10
DE60020501D1 (de) 2005-07-07
AU780011B2 (en) 2005-02-24
CN1166408C (zh) 2004-09-15
FR2802424A1 (fr) 2001-06-22
ZA200007548B (en) 2001-06-19
CZ299461B6 (cs) 2008-08-06

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