GEP20053540B - Matrix Tablet for Sustained Release of Trimetazidine after Oral Administration - Google Patents
Matrix Tablet for Sustained Release of Trimetazidine after Oral AdministrationInfo
- Publication number
- GEP20053540B GEP20053540B GE4838A GEAP2000004838A GEP20053540B GE P20053540 B GEP20053540 B GE P20053540B GE 4838 A GE4838 A GE 4838A GE AP2000004838 A GEAP2000004838 A GE AP2000004838A GE P20053540 B GEP20053540 B GE P20053540B
- Authority
- GE
- Georgia
- Prior art keywords
- matrix tablet
- trimetazidine
- oral administration
- sustained release
- stenocardia
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1. Technical Result Stabilization of blood circulation. 2. Essence A matrix tablet additionally comprising polymer of cellulose derivatives to control prolonged release, method for production and use thereof for preventive treatment of stenocardia, chorioretinal attacks and vertigo of circulatory origin. 3. Field of Application Medicine.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9915960A FR2802424B1 (en) | 1999-12-17 | 1999-12-17 | MATRIX TABLET FOR THE EXTENDED RELEASE OF TRIMETAZIDINE AFTER ORAL ADMINISTRATION |
Publications (1)
Publication Number | Publication Date |
---|---|
GEP20053540B true GEP20053540B (en) | 2005-06-10 |
Family
ID=9553398
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GE4838A GEP20053540B (en) | 1999-12-17 | 2000-12-15 | Matrix Tablet for Sustained Release of Trimetazidine after Oral Administration |
Country Status (33)
Country | Link |
---|---|
EP (1) | EP1108424B2 (en) |
JP (2) | JP2001172181A (en) |
KR (1) | KR100456933B1 (en) |
CN (1) | CN1166408C (en) |
AR (1) | AR026968A1 (en) |
AT (1) | ATE296622T1 (en) |
AU (1) | AU780011B2 (en) |
BG (1) | BG65773B1 (en) |
BR (1) | BR0005915A (en) |
CY (1) | CY2347B1 (en) |
CZ (1) | CZ299461B6 (en) |
DE (1) | DE60020501T3 (en) |
DK (1) | DK1108424T4 (en) |
EA (2) | EA008223B1 (en) |
ES (2) | ES2176106B1 (en) |
FR (1) | FR2802424B1 (en) |
GE (1) | GEP20053540B (en) |
GR (1) | GR1003658B (en) |
HK (1) | HK1036937A1 (en) |
HU (1) | HU226956B1 (en) |
IE (1) | IE20001017A1 (en) |
IT (1) | IT1317075B1 (en) |
LU (1) | LU90700B1 (en) |
MX (1) | MXPA00012462A (en) |
NZ (1) | NZ508912A (en) |
OA (1) | OA12121A (en) |
PL (1) | PL206994B1 (en) |
PT (2) | PT1108424E (en) |
SI (1) | SI1108424T2 (en) |
SK (1) | SK286752B6 (en) |
UA (1) | UA80087C2 (en) |
WO (1) | WO2001043747A1 (en) |
ZA (1) | ZA200007548B (en) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1195160E (en) * | 2000-10-05 | 2009-12-07 | Usv Ltd | Sustained release trimetazidine pharmaceutical compositions and a method of their preparation |
CA2532714C (en) | 2003-08-04 | 2010-11-16 | Kyorin Pharmaceutical Co., Ltd. | Oral sustained-release tablet comprising 4-(2-methyl-1-imidazolyl)-2,2-diphenylbutylamide |
SG126792A1 (en) * | 2005-04-27 | 2006-11-29 | Servier Lab | Matrix tablet enabling the prolonged release of trimetazidine after administration by the oral route |
FR2885807B1 (en) * | 2005-05-18 | 2008-05-16 | Mg Pharma | SOLID PHARMACEUTICAL COMPOSITION WITH PROLONGED RELEASE OF 1- (2,3,4-TRIMETHOXYBENZYL) PIPERAZINE, AND PREPARATION METHOD |
CZ300307B6 (en) * | 2006-01-04 | 2009-04-15 | Zentiva, A. S. | Modified release tablet containing trimetazidine or pharmacologically acceptable salts thereof |
EA009776B1 (en) * | 2006-07-18 | 2008-04-28 | Мераб Ревазович Кокеладзе | Method for preparing tablets of dihydrochloride trimethazine and composition thereof |
EA009810B1 (en) * | 2006-12-26 | 2008-04-28 | Закрытое Акционерное Общество "Канонфарма Продакшн" | Matrix for manufacturing tableted dosage form and method of treatment |
EP2200591A2 (en) * | 2007-09-11 | 2010-06-30 | Ranbaxy Laboratories Limited | Controlled release pharmaceutical dosage forms of trimetazidine |
JP2012515757A (en) | 2009-01-20 | 2012-07-12 | マイクロ ラブス リミテッド | Trimetazidine controlled release solid pharmaceutical composition and method for producing the same |
HUE027498T2 (en) * | 2009-01-30 | 2016-10-28 | Lupin Ltd | Pharmaceutical compositions of trimetazidine |
TR201001902A2 (en) | 2010-03-12 | 2011-04-21 | Ali̇ Rai̇f İlaç Sanayi̇ Ve Ti̇caret A.Ş. | Trimetazidine tablets with extended release |
RU2445958C2 (en) * | 2010-04-20 | 2012-03-27 | Общество с ограниченной ответственностью "Озон" (ООО "Озон") | Matrix tablet with trimetazidine prolonged-release base and method for preparing it |
ES2508490T3 (en) | 2010-05-04 | 2014-10-16 | Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi | Formulation of trimetazidine with different release profiles |
EP2386302A1 (en) | 2010-05-11 | 2011-11-16 | Ranbaxy Laboratories Limited | A controlled release pharmaceutical dosage form of trimetazidine and processes for the preparation thereof |
EP2491930A1 (en) | 2011-02-25 | 2012-08-29 | Deva Holding Anonim Sirketi | Pharmaceutical combination of betahistine and trimetazidine |
FR2978916B1 (en) * | 2011-08-10 | 2013-07-26 | Servier Lab | SOLID PHARMACEUTICAL COMPOSITION FOR BUCCAL ADMINISTRATION OF AGOMELATIN |
FR2986431B1 (en) * | 2012-02-03 | 2017-03-17 | Servier Lab | PROLONGED RELEASE OF TRIMETAZIDINE PHARMACEUTICAL COMPOSITION, PROCESS FOR THE PRODUCTION THEREOF AND USE IN THERAPEUTIC TREATMENTS |
CN102824644B (en) * | 2012-09-13 | 2013-12-25 | 浙江诚意药业有限公司 | High-stability sustained-release tablet prepared by using hydroxy propyl cellulose |
KR20160118733A (en) | 2015-04-03 | 2016-10-12 | 이인현 | Hose guide apparatus for hose winder and hose winder |
CN109316455B (en) * | 2017-07-31 | 2021-05-25 | 北京福元医药股份有限公司 | Trimetazidine hydrochloride sustained release tablet |
CN109908096A (en) * | 2017-12-12 | 2019-06-21 | 武汉武药科技有限公司 | A kind of trimetazidine hydrochloride sustained-release tablets and preparation method thereof |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4226849A (en) * | 1979-06-14 | 1980-10-07 | Forest Laboratories Inc. | Sustained release therapeutic compositions |
FR2490963B1 (en) * | 1980-09-30 | 1986-04-18 | Science Union & Cie | NOVEL THERAPEUTIC COMPOSITION WITH ANTI-ISCHEMIC ACTION CONTAINING TRIMETHOXY 2, 3, 4-BENZYL 1-PIPERAZINE |
KR850006132A (en) * | 1984-02-29 | 1985-10-02 | 진 크라메르, 한스 루돌프 하우스 | Bromocriptine Composition |
JPS61293931A (en) * | 1985-06-24 | 1986-12-24 | Teijin Ltd | Slow-releasing pharmaceutical composition |
JPH0625055B2 (en) * | 1985-03-18 | 1994-04-06 | 日本ケミフア株式会社 | Persistent tablets |
EP0207638B1 (en) † | 1985-06-04 | 1990-12-19 | Teijin Limited | Sustained-release pharmaceutical preparation |
SE455836B (en) * | 1985-10-11 | 1988-08-15 | Haessle Ab | PREPARATION WITH CONTROLLED RELEASE CONTAINING A SALT OF METOPROLOL AND METHOD FOR PREPARING THIS PREPARATION |
SE8601624D0 (en) * | 1986-04-11 | 1986-04-11 | Haessle Ab | NEW PHARMACEUTICAL PREPARATIONS |
FR2677886B1 (en) * | 1991-06-18 | 1995-03-31 | Adir | MATRIX TABLET FOR THE EXTENDED RELEASE OF INDAPAMIDE AFTER ORAL ADMINISTRATION. |
FR2681324B1 (en) * | 1991-09-18 | 1993-10-29 | Adir Cie | NOVEL TRIMETAZIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
KR940021051A (en) * | 1993-03-03 | 1994-10-17 | 손정삼 | 3-step drug release sustained tablet |
RU2082400C1 (en) * | 1993-12-16 | 1997-06-27 | Акционерное общество - Фармацевтическая фирма "Ник-Фарм" | Method of nitroglycerol prolonged action preparing |
FR2717687B1 (en) * | 1994-03-24 | 1996-06-14 | Adir | Pharmaceutical compositions for the sustained release of trimetazidine after oral administration. |
-
1999
- 1999-12-17 FR FR9915960A patent/FR2802424B1/en not_active Expired - Fee Related
-
2000
- 2000-12-11 JP JP2000375812A patent/JP2001172181A/en active Pending
- 2000-12-14 IT IT2000RM000667A patent/IT1317075B1/en active
- 2000-12-14 CY CY0000059A patent/CY2347B1/en unknown
- 2000-12-14 AU AU72285/00A patent/AU780011B2/en not_active Expired
- 2000-12-14 MX MXPA00012462A patent/MXPA00012462A/en active IP Right Grant
- 2000-12-15 PL PL344564A patent/PL206994B1/en not_active IP Right Cessation
- 2000-12-15 CZ CZ20022082A patent/CZ299461B6/en not_active IP Right Cessation
- 2000-12-15 ES ES200003018A patent/ES2176106B1/en not_active Expired - Fee Related
- 2000-12-15 SK SK863-2002A patent/SK286752B6/en not_active IP Right Cessation
- 2000-12-15 WO PCT/FR2000/003546 patent/WO2001043747A1/en active IP Right Grant
- 2000-12-15 NZ NZ508912A patent/NZ508912A/en not_active IP Right Cessation
- 2000-12-15 ES ES00403533.3T patent/ES2240033T5/en not_active Expired - Lifetime
- 2000-12-15 DK DK00403533.3T patent/DK1108424T4/en active
- 2000-12-15 HU HU0004966A patent/HU226956B1/en active IP Right Maintenance
- 2000-12-15 ZA ZA200007548A patent/ZA200007548B/en unknown
- 2000-12-15 SI SI200030704T patent/SI1108424T2/en unknown
- 2000-12-15 DE DE60020501.0T patent/DE60020501T3/en not_active Expired - Lifetime
- 2000-12-15 PT PT00403533T patent/PT1108424E/en unknown
- 2000-12-15 OA OA1200200181A patent/OA12121A/en unknown
- 2000-12-15 GE GE4838A patent/GEP20053540B/en unknown
- 2000-12-15 EP EP00403533.3A patent/EP1108424B2/en not_active Expired - Lifetime
- 2000-12-15 LU LU90700A patent/LU90700B1/en active
- 2000-12-15 CN CNB001380605A patent/CN1166408C/en not_active Expired - Lifetime
- 2000-12-15 AT AT00403533T patent/ATE296622T1/en active
- 2000-12-15 PT PT102542A patent/PT102542A/en not_active IP Right Cessation
- 2000-12-15 UA UA2002075914A patent/UA80087C2/en unknown
- 2000-12-15 IE IE20001017A patent/IE20001017A1/en not_active Application Discontinuation
- 2000-12-15 KR KR10-2000-0076962A patent/KR100456933B1/en active IP Right Review Request
- 2000-12-15 AR ARP000106662A patent/AR026968A1/en not_active Application Discontinuation
- 2000-12-15 GR GR20000100433A patent/GR1003658B/en unknown
- 2000-12-18 EA EA200001201A patent/EA008223B1/en not_active IP Right Cessation
- 2000-12-18 EA EA200501901A patent/EA200501901A1/en unknown
- 2000-12-18 BR BR0005915-3A patent/BR0005915A/en not_active Application Discontinuation
-
2001
- 2001-11-12 HK HK01107928A patent/HK1036937A1/en not_active IP Right Cessation
-
2002
- 2002-07-16 BG BG106927A patent/BG65773B1/en unknown
-
2007
- 2007-08-31 JP JP2007224959A patent/JP2007314578A/en active Pending
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