EA200001201A2 - Таблетка с основой, позволяющая осуществлять пролонгированное высвобождение триметазидина после введения оральным путем - Google Patents

Таблетка с основой, позволяющая осуществлять пролонгированное высвобождение триметазидина после введения оральным путем

Info

Publication number
EA200001201A2
EA200001201A2 EA200001201A EA200001201A EA200001201A2 EA 200001201 A2 EA200001201 A2 EA 200001201A2 EA 200001201 A EA200001201 A EA 200001201A EA 200001201 A EA200001201 A EA 200001201A EA 200001201 A2 EA200001201 A2 EA 200001201A2
Authority
EA
Eurasian Patent Office
Prior art keywords
trimetazidine
prolonged release
matrix tablet
release
tablet
Prior art date
Application number
EA200001201A
Other languages
English (en)
Other versions
EA008223B1 (ru
EA200001201A3 (ru
Inventor
Бруно От Де Бароше
Клод Дюфан
Патрик Вутриш
Original Assignee
Адир Э Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9553398&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200001201(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Адир Э Компани filed Critical Адир Э Компани
Publication of EA200001201A2 publication Critical patent/EA200001201A2/ru
Publication of EA200001201A3 publication Critical patent/EA200001201A3/ru
Publication of EA008223B1 publication Critical patent/EA008223B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

В заявке описана таблетка с основой, обладающая способностью пролонгировать высвобождение триметазидина или его фармацевтически приемлемой кислотно-аддитивной соли после введения оральным путем, отличающаяся тем, что пролонгированное высвобождение контролируют с использованием полимера, являющегося производным целлюлозы.
EA200001201A 1999-12-17 2000-12-18 Матричная таблетка с основой для пролонгированного высвобождения триметазидина EA008223B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9915960A FR2802424B1 (fr) 1999-12-17 1999-12-17 Comprime matriciel permettant la liberation prolongee de trimetazidine apres administration par voie orale

Publications (3)

Publication Number Publication Date
EA200001201A2 true EA200001201A2 (ru) 2001-08-27
EA200001201A3 EA200001201A3 (ru) 2001-10-22
EA008223B1 EA008223B1 (ru) 2007-04-27

Family

ID=9553398

Family Applications (2)

Application Number Title Priority Date Filing Date
EA200001201A EA008223B1 (ru) 1999-12-17 2000-12-18 Матричная таблетка с основой для пролонгированного высвобождения триметазидина
EA200501901A EA200501901A1 (ru) 1999-12-17 2000-12-18 Таблетка с основой, позволяющая осуществлять пролонгированное высвобождение триметазидина после введения оральным путём

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA200501901A EA200501901A1 (ru) 1999-12-17 2000-12-18 Таблетка с основой, позволяющая осуществлять пролонгированное высвобождение триметазидина после введения оральным путём

Country Status (33)

Country Link
EP (1) EP1108424B2 (ru)
JP (2) JP2001172181A (ru)
KR (1) KR100456933B1 (ru)
CN (1) CN1166408C (ru)
AR (1) AR026968A1 (ru)
AT (1) ATE296622T1 (ru)
AU (1) AU780011B2 (ru)
BG (1) BG65773B1 (ru)
BR (1) BR0005915A (ru)
CY (1) CY2347B1 (ru)
CZ (1) CZ299461B6 (ru)
DE (1) DE60020501T3 (ru)
DK (1) DK1108424T4 (ru)
EA (2) EA008223B1 (ru)
ES (2) ES2240033T5 (ru)
FR (1) FR2802424B1 (ru)
GE (1) GEP20053540B (ru)
GR (1) GR1003658B (ru)
HK (1) HK1036937A1 (ru)
HU (1) HU226956B1 (ru)
IE (1) IE20001017A1 (ru)
IT (1) IT1317075B1 (ru)
LU (1) LU90700B1 (ru)
MX (1) MXPA00012462A (ru)
NZ (1) NZ508912A (ru)
OA (1) OA12121A (ru)
PL (1) PL206994B1 (ru)
PT (2) PT1108424E (ru)
SI (1) SI1108424T2 (ru)
SK (1) SK286752B6 (ru)
UA (1) UA80087C2 (ru)
WO (1) WO2001043747A1 (ru)
ZA (1) ZA200007548B (ru)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA009776B1 (ru) * 2006-07-18 2008-04-28 Мераб Ревазович Кокеладзе Способ изготовления таблетированной лекарственной формы триметазидина дигидрохлорида и ее состав
EA009810B1 (ru) * 2006-12-26 2008-04-28 Закрытое Акционерное Общество "Канонфарма Продакшн" Матрица для изготовления таблетированной лекарственной формы и способ лечения

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE442852T1 (de) * 2000-10-05 2009-10-15 Usv Ltd Trimetazidine enthaltendes arzneimittel mit verzögerter wirkstoffabgabe und verfahren zur herstellung
KR101175816B1 (ko) * 2003-08-04 2012-08-24 교린 세이야꾸 가부시키 가이샤 경구 서방성 정제
SG126792A1 (en) * 2005-04-27 2006-11-29 Servier Lab Matrix tablet enabling the prolonged release of trimetazidine after administration by the oral route
FR2885807B1 (fr) * 2005-05-18 2008-05-16 Mg Pharma Composition pharmaceutique solide a liberation prolongee de 1-(2,3,4-trimethoxybenzyl) piperazine, et procede de preparation
CZ300307B6 (cs) * 2006-01-04 2009-04-15 Zentiva, A. S. Tableta s obsahem trimetazidinu nebo jeho farmakologicky akceptovatelné soli s modifikovaným uvolnováním
EP2200591A2 (en) * 2007-09-11 2010-06-30 Ranbaxy Laboratories Limited Controlled release pharmaceutical dosage forms of trimetazidine
JP2012515757A (ja) 2009-01-20 2012-07-12 マイクロ ラブス リミテッド トリメタジジンの放出調節固形薬剤組成物及びその製造方法
HUE027498T2 (en) * 2009-01-30 2016-10-28 Lupin Ltd Pharmaceutical preparations containing trimetazidine
TR201001902A2 (tr) 2010-03-12 2011-04-21 Ali̇ Rai̇f İlaç Sanayi̇ Ve Ti̇caret A.Ş. Uzatılmış salınımlı trimetazidin tablet
RU2445958C2 (ru) * 2010-04-20 2012-03-27 Общество с ограниченной ответственностью "Озон" (ООО "Озон") Матричная таблетка с основой для пролонгированного высвобождения триметазидина и способ ее изготовления
ES2508490T3 (es) 2010-05-04 2014-10-16 Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi Formulación de trimetazidina con diferentes perfiles de liberación
EP2386302A1 (en) 2010-05-11 2011-11-16 Ranbaxy Laboratories Limited A controlled release pharmaceutical dosage form of trimetazidine and processes for the preparation thereof
EP2491930A1 (en) 2011-02-25 2012-08-29 Deva Holding Anonim Sirketi Pharmaceutical combination of betahistine and trimetazidine
FR2978916B1 (fr) * 2011-08-10 2013-07-26 Servier Lab Composition pharmaceutique solide pour administration buccale d'agomelatine
FR2986431B1 (fr) * 2012-02-03 2017-03-17 Servier Lab Composition pharmaceutique a liberation prolongee de trimetazidine, son procede de fabrication et son utilisation dans des traitements therapeutiques
CN102824644B (zh) * 2012-09-13 2013-12-25 浙江诚意药业有限公司 使用羟丙基纤维素制备的高稳定性的缓释片
KR20160118733A (ko) 2015-04-03 2016-10-12 이인현 호스 권취용 호스 안내장치 및 이를 구비한 호스 권취기
CN109316455B (zh) * 2017-07-31 2021-05-25 北京福元医药股份有限公司 一种盐酸曲美他嗪缓释片
CN109908096A (zh) * 2017-12-12 2019-06-21 武汉武药科技有限公司 一种盐酸曲美他嗪缓释片及其制备方法

Family Cites Families (13)

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Publication number Priority date Publication date Assignee Title
US4226849A (en) * 1979-06-14 1980-10-07 Forest Laboratories Inc. Sustained release therapeutic compositions
FR2490963B1 (fr) * 1980-09-30 1986-04-18 Science Union & Cie Nouvelle composition therapeutique a action anti-ischemique contenant de la trimethoxy 2, 3, 4-benzyl 1-piperazine
KR850006132A (ko) * 1984-02-29 1985-10-02 진 크라메르, 한스 루돌프 하우스 브로모크립틴 조성물
JPS61293931A (ja) * 1985-06-24 1986-12-24 Teijin Ltd 徐放性医薬品組成物
JPH0625055B2 (ja) * 1985-03-18 1994-04-06 日本ケミフア株式会社 持続性錠剤
EP0207638B1 (en) † 1985-06-04 1990-12-19 Teijin Limited Sustained-release pharmaceutical preparation
SE455836B (sv) * 1985-10-11 1988-08-15 Haessle Ab Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning
SE8601624D0 (sv) * 1986-04-11 1986-04-11 Haessle Ab New pharmaceutical preparations
FR2677886B1 (fr) * 1991-06-18 1995-03-31 Adir Comprime matriciel permettant la liberation prolongee d'indapamide apres administration par voie orale.
FR2681324B1 (fr) * 1991-09-18 1993-10-29 Adir Cie Nouveaux derives de la trimetazidine, leur procede de preparation et les compositions pharmaceutiques les contenant.
KR940021051A (ko) * 1993-03-03 1994-10-17 손정삼 3단계 약물방출형 지속성 정제
RU2082400C1 (ru) * 1993-12-16 1997-06-27 Акционерное общество - Фармацевтическая фирма "Ник-Фарм" Способ получения нитроглицерина пролонгированного действия
FR2717687B1 (fr) * 1994-03-24 1996-06-14 Adir Compositions pharmaceutiques permettant la libération prolongée de trimétazidine après administration par voie orale.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA009776B1 (ru) * 2006-07-18 2008-04-28 Мераб Ревазович Кокеладзе Способ изготовления таблетированной лекарственной формы триметазидина дигидрохлорида и ее состав
EA009810B1 (ru) * 2006-12-26 2008-04-28 Закрытое Акционерное Общество "Канонфарма Продакшн" Матрица для изготовления таблетированной лекарственной формы и способ лечения

Also Published As

Publication number Publication date
ITRM20000667A0 (it) 2000-12-14
HUP0004966A2 (en) 2002-06-29
FR2802424A1 (fr) 2001-06-22
KR20010062478A (ko) 2001-07-07
EP1108424A1 (fr) 2001-06-20
HU0004966D0 (ru) 2001-02-28
IE20001017A1 (en) 2002-04-03
PT102542A (pt) 2001-06-29
DE60020501T2 (de) 2006-04-27
NZ508912A (en) 2002-04-26
EA008223B1 (ru) 2007-04-27
SK8632002A3 (en) 2002-10-08
WO2001043747A1 (fr) 2001-06-21
CN1166408C (zh) 2004-09-15
EA200001201A3 (ru) 2001-10-22
ES2240033T5 (es) 2014-01-16
PL206994B1 (pl) 2010-10-29
JP2001172181A (ja) 2001-06-26
EA200501901A1 (ru) 2006-06-30
SI1108424T2 (sl) 2014-02-28
EP1108424B2 (fr) 2013-09-04
HU226956B1 (en) 2010-03-29
ES2240033T3 (es) 2005-10-16
ATE296622T1 (de) 2005-06-15
ITRM20000667A1 (it) 2002-06-14
IT1317075B1 (it) 2003-05-26
DK1108424T4 (da) 2013-12-16
KR100456933B1 (ko) 2004-11-10
ZA200007548B (en) 2001-06-19
ES2176106A1 (es) 2002-11-16
JP2007314578A (ja) 2007-12-06
ES2176106B1 (es) 2004-01-16
CN1302663A (zh) 2001-07-11
GEP20053540B (en) 2005-06-10
CZ299461B6 (cs) 2008-08-06
DE60020501T3 (de) 2014-03-20
MXPA00012462A (es) 2002-06-04
AU780011B2 (en) 2005-02-24
AU7228500A (en) 2001-06-21
UA80087C2 (en) 2007-08-27
DK1108424T3 (da) 2005-10-03
PL344564A1 (en) 2001-06-18
BG106927A (en) 2003-05-30
PT1108424E (pt) 2005-08-31
CZ20022082A3 (cs) 2002-09-11
BR0005915A (pt) 2001-10-02
GR1003658B (el) 2001-09-05
DE60020501D1 (de) 2005-07-07
SI1108424T1 (en) 2005-10-31
WO2001043747A8 (fr) 2001-09-07
AR026968A1 (es) 2003-03-05
SK286752B6 (sk) 2009-04-06
CY2347B1 (en) 2004-06-04
HK1036937A1 (en) 2002-01-25
OA12121A (en) 2003-10-20
LU90700B1 (fr) 2007-12-03
EP1108424B1 (fr) 2005-06-01
HUP0004966A3 (en) 2008-04-28
FR2802424B1 (fr) 2002-02-15
BG65773B1 (bg) 2009-11-30

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Legal Events

Date Code Title Description
MH4D Revocation of a eurasian patent in part

Designated state(s): RU

QB4A Registration of a licence in a contracting state
QB4A Registration of a licence in a contracting state
MK4A Patent expired

Designated state(s): AM AZ BY KZ KG MD TJ TM RU