CY1105120T1 - Η αντιμετωπιση αναπνευστικων νοσων - Google Patents
Η αντιμετωπιση αναπνευστικων νοσωνInfo
- Publication number
- CY1105120T1 CY1105120T1 CY20061101079T CY061101079T CY1105120T1 CY 1105120 T1 CY1105120 T1 CY 1105120T1 CY 20061101079 T CY20061101079 T CY 20061101079T CY 061101079 T CY061101079 T CY 061101079T CY 1105120 T1 CY1105120 T1 CY 1105120T1
- Authority
- CY
- Cyprus
- Prior art keywords
- treatment
- respiratory diseases
- glycopyrrolate
- exerts
- administration
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000000241 respiratory effect Effects 0.000 title 1
- VPNYRYCIDCJBOM-UHFFFAOYSA-M Glycopyrronium bromide Chemical compound [Br-].C1[N+](C)(C)CCC1OC(=O)C(O)(C=1C=CC=CC=1)C1CCCC1 VPNYRYCIDCJBOM-UHFFFAOYSA-M 0.000 abstract 2
- 229940015042 glycopyrrolate Drugs 0.000 abstract 2
- 238000013270 controlled release Methods 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 230000002685 pulmonary effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Μία φαρμακευτική σύνθεση για πνευμονική διανομή περιλαμβάνει γλυκοπυρρολικό σε μία μορφοποίηση ελεγχόμενης αποδέσμευσης, όπου, κατά τη χορήγηση, το γλυκοπυρρολικό ασκεί τη φαρμακολογική του επίδραση επί περίοδο μεγαλύτερη από 12 ώρες.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0008660.3A GB0008660D0 (en) | 2000-04-07 | 2000-04-07 | The treatment of respiratory diseases |
PCT/GB2001/001606 WO2001076575A2 (en) | 2000-04-07 | 2001-04-09 | The treatment of respiratory diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1105120T1 true CY1105120T1 (el) | 2010-03-03 |
Family
ID=9889490
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20061101079T CY1105120T1 (el) | 2000-04-07 | 2006-07-31 | Η αντιμετωπιση αναπνευστικων νοσων |
Country Status (25)
Country | Link |
---|---|
US (3) | US7229607B2 (el) |
EP (3) | EP2193791A1 (el) |
JP (1) | JP5042426B2 (el) |
CN (3) | CN101181263B (el) |
AT (1) | ATE330585T2 (el) |
AU (2) | AU2004242450B2 (el) |
BE (1) | BE2013C023I2 (el) |
BR (1) | BR0109875A (el) |
CA (1) | CA2405705C (el) |
CY (1) | CY1105120T1 (el) |
DE (1) | DE60120936T3 (el) |
DK (1) | DK1267866T4 (el) |
ES (2) | ES2687751T3 (el) |
GB (1) | GB0008660D0 (el) |
HK (1) | HK1050846B (el) |
HU (2) | HU230958B1 (el) |
IL (2) | IL151791A0 (el) |
LU (2) | LU92166I2 (el) |
MX (1) | MXPA02009718A (el) |
NO (3) | NO336142B1 (el) |
NZ (2) | NZ521476A (el) |
PL (1) | PL364024A1 (el) |
PT (1) | PT1267866E (el) |
WO (1) | WO2001076575A2 (el) |
ZA (1) | ZA200207420B (el) |
Families Citing this family (66)
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GB0008660D0 (en) * | 2000-04-07 | 2000-05-31 | Arakis Ltd | The treatment of respiratory diseases |
ES2708961T3 (es) | 2000-11-30 | 2019-04-12 | Vectura Ltd | Composiciones farmacéuticas para inhalación |
DE60140268D1 (de) | 2000-11-30 | 2009-12-03 | Vectura Ltd | Partikel zur verwendung in einer pharmazeutischen zusammensetzung |
CA2341952A1 (en) * | 2001-03-23 | 2002-09-23 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory pulmonary diseases |
US20050130990A1 (en) * | 2001-03-23 | 2005-06-16 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory diseases |
WO2002094320A1 (fr) | 2001-05-23 | 2002-11-28 | Tanabe Seiyaku Co., Ltd. | Compositions therapeutiques permettant de reparer la chondropathie |
CN1520313A (zh) | 2001-05-23 | 2004-08-11 | ������ҩ��ʽ���� | 一种加速骨折愈合的组合物 |
ES2779273T3 (es) * | 2002-03-01 | 2020-08-14 | Chiesi Farm Spa | Formulación superfina de formoterol |
US8039459B2 (en) * | 2004-07-15 | 2011-10-18 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory diseases |
US8557804B2 (en) | 2002-03-25 | 2013-10-15 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory diseases |
US20040121003A1 (en) * | 2002-12-19 | 2004-06-24 | Acusphere, Inc. | Methods for making pharmaceutical formulations comprising deagglomerated microparticles |
CA2534352A1 (en) * | 2003-08-08 | 2005-02-17 | Arriva Pharmaceuticals, Inc. | Methods of protein production in yeast |
GB0327723D0 (en) * | 2003-09-15 | 2003-12-31 | Vectura Ltd | Pharmaceutical compositions |
PT1684719E (pt) * | 2003-11-14 | 2012-02-03 | Baxter Int | Composições de alfa-1-antitripsina e métodos de tratamento utilizando estas composições |
NZ548302A (en) * | 2004-02-06 | 2010-04-30 | Meda Pharma Gmbh & Co Kg | Novel combination of anticholinergic and beta mimetics for the treatment of respiratory diseases |
CN100569235C (zh) | 2004-02-06 | 2009-12-16 | Meda制药有限及两合公司 | 用于哮喘和copd长期治疗的抗胆碱能药和糖皮质激素的组合 |
CA2552458A1 (en) * | 2004-02-06 | 2005-08-18 | Meda Pharma Gmbh & Co. Kg | Treatment of rhinitis with anticholinergics alone in combination with antihistamines phosphodiesterase 4 inhibitors, or corticosteroids |
EP1713471B1 (en) * | 2004-02-06 | 2012-01-18 | MEDA Pharma GmbH & Co. KG | Combination of anticholinergics and inhibitors of phosphodiesterase type 4 for the treatment of respiratory diseases |
EP1720577A2 (en) * | 2004-02-27 | 2006-11-15 | Altana Pharma AG | Ciclesonide and glycopyrronium combination |
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GB0410398D0 (en) * | 2004-05-10 | 2004-06-16 | Arakis Ltd | The treatment of respiratory disease |
GB0410399D0 (en) * | 2004-05-10 | 2004-06-16 | Arakis Ltd | The treatment of respiratory disease |
GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
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EP1616567A1 (en) * | 2004-07-16 | 2006-01-18 | Boehringer Ingelheim Pharma GmbH & Co.KG | Medicaments for inhalation comprising PDE IV inhibitors and glycopyrrolate salts |
WO2006026502A1 (en) | 2004-08-27 | 2006-03-09 | The Dow Chemical Company | Enhanced delivery of drug compositions to treat life threatening infections |
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GB0425758D0 (en) * | 2004-11-23 | 2004-12-22 | Vectura Ltd | Preparation of pharmaceutical compositions |
JP5288791B2 (ja) * | 2005-01-28 | 2013-09-11 | 武田薬品工業株式会社 | 難水溶性物質含有微細化組成物 |
JP4991693B2 (ja) | 2005-03-16 | 2012-08-01 | メダ ファーマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | 呼吸器疾患の治療のための抗コリン作用薬及びロイコトリエン受容体アンタゴニストの組み合わせ剤 |
JP2008534480A (ja) * | 2005-03-24 | 2008-08-28 | ソーセイ アールアンドディ リミテッド | グリコピロニウム塩およびそれらの治療的使用 |
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ES2330047T3 (es) | 2005-12-21 | 2009-12-03 | MEDA PHARMA GMBH & CO. KG | Combinacion de r,r-glicopirrolato, rolipram y budesonida para el tratmiento de enfermedades inflamatorias. |
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US20090062326A1 (en) * | 2006-03-17 | 2009-03-05 | Spindel Eliot R | M3 muscarinic receptor antagonists for treatment of m3 muscarinic receptor-expressing tumors |
GB0613161D0 (en) * | 2006-06-30 | 2006-08-09 | Novartis Ag | Organic Compounds |
AU2008334547B2 (en) * | 2007-12-13 | 2011-06-30 | Novartis Ag | Organic compounds |
CA2708083C (en) * | 2007-12-13 | 2016-06-28 | Novartis Ag | Organic compounds |
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US8815258B2 (en) | 2009-05-29 | 2014-08-26 | Pearl Therapeutics, Inc. | Compositions, methods and systems for respiratory delivery of two or more active agents |
GB0921075D0 (en) | 2009-12-01 | 2010-01-13 | Glaxo Group Ltd | Novel combination of the therapeutic agents |
EA021917B1 (ru) | 2009-12-23 | 2015-09-30 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Комбинированная терапия астмы и copd |
EP2515854B1 (en) | 2009-12-23 | 2014-03-19 | Chiesi Farmaceutici S.p.A. | Aerosol formualtion for COPD |
RU2561052C2 (ru) | 2009-12-23 | 2015-08-20 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Комбинированное лечение хронического обструктивного заболевания легких |
EP2515856B1 (en) | 2009-12-23 | 2014-04-02 | Chiesi Farmaceutici S.p.A. | Aerosol Formulation for COPD |
AU2011308865B2 (en) | 2010-09-29 | 2017-01-05 | Pulmatrix, Inc. | Monovalent metal cation dry powders for inhalation |
JOP20120023B1 (ar) | 2011-02-04 | 2022-03-14 | Novartis Ag | صياغات مساحيق جافة من جسيمات تحتوي على واحد أو اثنين من المواد الفعالة لعلاج امراض ممرات الهواء الانسدادية او الالتهابية |
CN103841960B (zh) | 2011-08-01 | 2017-07-07 | 莫纳什大学 | 用于吸入的方法和制剂 |
CN107596518B (zh) | 2012-02-29 | 2021-04-23 | 普马特里克斯营业公司 | 可吸入干粉剂 |
EP2968152B2 (en) | 2013-03-15 | 2022-06-22 | Pearl Therapeutics, Inc. | Methods and systems for conditioning of particulate crystalline materials |
EP2981247B1 (en) | 2013-04-01 | 2023-06-07 | Pulmatrix Operating Company, Inc. | Tiotropium dry powders |
US9393202B2 (en) | 2013-04-26 | 2016-07-19 | Chiesi Farmaceutici S.P.A | Particle size reduction of an antimuscarinic compound |
WO2015094927A1 (en) * | 2013-12-17 | 2015-06-25 | Merck Sharp & Dohme Corp. | Media milling process for the manufacture of active pharmaceutical ingredients in propellants |
MX368835B (es) | 2013-12-30 | 2019-10-18 | Chiesi Farm Spa | Composición combinada de bromuro de glicopirronio y formoterol en solución estable presurizada para aerosol. |
US10532041B2 (en) | 2014-09-09 | 2020-01-14 | Vectura Limited | Formulation comprising glycopyrrolate, method and apparatus |
EP3494962B1 (en) * | 2014-09-15 | 2021-05-26 | Verona Pharma PLC | Liquid inhalation formulation comprising rpl554 |
MA41378A (fr) * | 2015-01-20 | 2017-11-28 | Teva Branded Pharmaceutical Prod R & D Inc | Inhalateur de poudre sèche comprenant du propionate de fluticasone et du xinafoate de salmétérol |
WO2016170518A1 (en) | 2015-04-24 | 2016-10-27 | Glenmark Specialty S.A. | Pharmaceutical compositions comprising arformoterol and glycopyrronium |
AU2016279798B2 (en) * | 2015-06-15 | 2021-07-08 | Qaam Pharmaceuticals, Llc | Glycopyrronium fatty acid salts and methods of making same |
US9925168B2 (en) * | 2016-01-22 | 2018-03-27 | Chiesi Farmaceutici S.P.A. | Preparation of micronized particles of an antimuscarinic compound by hydrodynamic cavitation |
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-
2000
- 2000-04-07 GB GBGB0008660.3A patent/GB0008660D0/en not_active Ceased
-
2001
- 2001-04-09 PT PT01966751T patent/PT1267866E/pt unknown
- 2001-04-09 MX MXPA02009718A patent/MXPA02009718A/es active IP Right Grant
- 2001-04-09 EP EP10153877A patent/EP2193791A1/en not_active Withdrawn
- 2001-04-09 CN CN2007101471670A patent/CN101181263B/zh not_active Expired - Lifetime
- 2001-04-09 WO PCT/GB2001/001606 patent/WO2001076575A2/en active IP Right Grant
- 2001-04-09 ES ES04011047.0T patent/ES2687751T3/es not_active Expired - Lifetime
- 2001-04-09 DE DE60120936.2T patent/DE60120936T3/de not_active Expired - Lifetime
- 2001-04-09 DK DK01966751.8T patent/DK1267866T4/en active
- 2001-04-09 PL PL01364024A patent/PL364024A1/xx not_active Application Discontinuation
- 2001-04-09 JP JP2001574093A patent/JP5042426B2/ja not_active Expired - Lifetime
- 2001-04-09 EP EP01966751.8A patent/EP1267866B2/en not_active Expired - Lifetime
- 2001-04-09 AT AT01966751T patent/ATE330585T2/de active
- 2001-04-09 EP EP04011047.0A patent/EP1449528B1/en not_active Expired - Lifetime
- 2001-04-09 IL IL15179101A patent/IL151791A0/xx unknown
- 2001-04-09 CN CNA200510076362XA patent/CN1720995A/zh active Pending
- 2001-04-09 NZ NZ521476A patent/NZ521476A/en not_active IP Right Cessation
- 2001-04-09 NZ NZ535284A patent/NZ535284A/xx not_active IP Right Cessation
- 2001-04-09 BR BR0109875-6A patent/BR0109875A/pt not_active Application Discontinuation
- 2001-04-09 CA CA2405705A patent/CA2405705C/en not_active Expired - Lifetime
- 2001-04-09 HU HU0301518A patent/HU230958B1/hu active Protection Beyond IP Right Term
- 2001-04-09 CN CNB018075584A patent/CN1292745C/zh not_active Expired - Lifetime
- 2001-04-09 ES ES01966751.8T patent/ES2266242T5/es not_active Expired - Lifetime
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2002
- 2002-09-16 ZA ZA200207420A patent/ZA200207420B/en unknown
- 2002-09-18 IL IL151791A patent/IL151791A/en active IP Right Grant
- 2002-10-01 NO NO20024708A patent/NO336142B1/no not_active IP Right Cessation
- 2002-10-07 US US10/266,717 patent/US7229607B2/en not_active Expired - Lifetime
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2003
- 2003-03-18 HK HK03101991.4A patent/HK1050846B/zh unknown
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2004
- 2004-08-24 US US10/926,196 patent/US7368104B2/en not_active Expired - Lifetime
- 2004-12-22 AU AU2004242450A patent/AU2004242450B2/en not_active Expired
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2006
- 2006-07-31 CY CY20061101079T patent/CY1105120T1/el unknown
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2008
- 2008-03-14 US US12/048,812 patent/US8029768B2/en not_active Expired - Lifetime
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2010
- 2010-02-23 AU AU2010200660A patent/AU2010200660B2/en active Active
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2013
- 2013-03-13 LU LU92166C patent/LU92166I2/fr unknown
- 2013-03-26 BE BE2013C023C patent/BE2013C023I2/fr unknown
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2014
- 2014-03-07 LU LU92393C patent/LU92393I2/xx unknown
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2015
- 2015-11-25 NO NO2015025C patent/NO2015025I1/no not_active Application Discontinuation
- 2015-11-25 NO NO2015024C patent/NO2015024I1/no not_active IP Right Cessation
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2019
- 2019-12-23 HU HUS1900056C patent/HUS1900056I1/hu unknown
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