LU92166I2 - Glycopyrronium ou un de ses sels - Google Patents

Glycopyrronium ou un de ses sels

Info

Publication number
LU92166I2
LU92166I2 LU92166C LU92166C LU92166I2 LU 92166 I2 LU92166 I2 LU 92166I2 LU 92166 C LU92166 C LU 92166C LU 92166 C LU92166 C LU 92166C LU 92166 I2 LU92166 I2 LU 92166I2
Authority
LU
Luxembourg
Prior art keywords
glycopyrrolate
dry powder
glycopyrronium
salt
formulation
Prior art date
Application number
LU92166C
Other languages
English (en)
Original Assignee
Sosei R & D Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9889490&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU92166(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sosei R & D Ltd filed Critical Sosei R & D Ltd
Publication of LU92166I2 publication Critical patent/LU92166I2/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
LU92166C 2000-04-07 2013-03-13 Glycopyrronium ou un de ses sels LU92166I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0008660.3A GB0008660D0 (en) 2000-04-07 2000-04-07 The treatment of respiratory diseases
PCT/GB2001/001606 WO2001076575A2 (fr) 2000-04-07 2001-04-09 Traitement de troubles respiratoires

Publications (1)

Publication Number Publication Date
LU92166I2 true LU92166I2 (fr) 2014-03-13

Family

ID=9889490

Family Applications (2)

Application Number Title Priority Date Filing Date
LU92166C LU92166I2 (fr) 2000-04-07 2013-03-13 Glycopyrronium ou un de ses sels
LU92393C LU92393I2 (fr) 2000-04-07 2014-03-07 Glycopyrronium ou un sel de celui-ci, plus particulièrement le sel bromure, combiné à indacatérol ouun sel de celui-ci, plus particulièrement le sel maléate

Family Applications After (1)

Application Number Title Priority Date Filing Date
LU92393C LU92393I2 (fr) 2000-04-07 2014-03-07 Glycopyrronium ou un sel de celui-ci, plus particulièrement le sel bromure, combiné à indacatérol ouun sel de celui-ci, plus particulièrement le sel maléate

Country Status (25)

Country Link
US (3) US7229607B2 (fr)
EP (3) EP1449528B1 (fr)
JP (1) JP5042426B2 (fr)
CN (3) CN101181263B (fr)
AT (1) ATE330585T2 (fr)
AU (2) AU2004242450B2 (fr)
BE (1) BE2013C023I2 (fr)
BR (1) BR0109875A (fr)
CA (1) CA2405705C (fr)
CY (1) CY1105120T1 (fr)
DE (1) DE60120936T3 (fr)
DK (1) DK1267866T4 (fr)
ES (2) ES2266242T5 (fr)
GB (1) GB0008660D0 (fr)
HK (1) HK1050846B (fr)
HU (2) HU230958B1 (fr)
IL (2) IL151791A0 (fr)
LU (2) LU92166I2 (fr)
MX (1) MXPA02009718A (fr)
NO (3) NO336142B1 (fr)
NZ (2) NZ535284A (fr)
PL (1) PL364024A1 (fr)
PT (1) PT1267866E (fr)
WO (1) WO2001076575A2 (fr)
ZA (1) ZA200207420B (fr)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0008660D0 (en) * 2000-04-07 2000-05-31 Arakis Ltd The treatment of respiratory diseases
ES2587135T3 (es) 2000-11-30 2016-10-20 Vectura Limited Procedimiento de fabricación de partículas para su uso en una composición farmacéutica
EP1337239B2 (fr) 2000-11-30 2015-11-25 Vectura Limited Particules servant dans une composition pharmaceutique
US20050130990A1 (en) * 2001-03-23 2005-06-16 Universite Laval Nicotinic receptor agonists for the treatment of inflammatory diseases
CA2341952A1 (fr) * 2001-03-23 2002-09-23 Universite Laval Agonistes du recepteur de la nicotine pour le traitement des maladies pulmonaires inflammatoires
JP4510384B2 (ja) 2001-05-23 2010-07-21 田辺三菱製薬株式会社 骨折治癒促進用組成物
EP1389467B1 (fr) 2001-05-23 2013-07-03 Mitsubishi Tanabe Pharma Corporation Composition thérapeutique permettant le traitement régénératif des maladies de cartilage
SI3494995T1 (sl) * 2002-03-01 2020-08-31 Chiesi Farmaceutici S.P.A. Superfina formulacija formoterola
US8557804B2 (en) 2002-03-25 2013-10-15 Universite Laval Nicotinic receptor agonists for the treatment of inflammatory diseases
US8039459B2 (en) * 2004-07-15 2011-10-18 Universite Laval Nicotinic receptor agonists for the treatment of inflammatory diseases
US20040121003A1 (en) * 2002-12-19 2004-06-24 Acusphere, Inc. Methods for making pharmaceutical formulations comprising deagglomerated microparticles
WO2005014825A2 (fr) * 2003-08-08 2005-02-17 Arriva Pharmaceuticals, Inc. Procede de production de proteines dans une levure
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
ES2375706T3 (es) * 2003-11-14 2012-03-05 Baxter International Inc. Composiciones de alfa 1-antitripsina y métodos de tratamiento que usan tales composiciones.
JP4819699B2 (ja) 2004-02-06 2011-11-24 メダ ファーマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディト ゲゼルシャフト 喘息及びｃｏｐｄの長期間の治療のための抗コリン作用薬及びグルココルチコイドの組合せ剤
EP1718336B1 (fr) 2004-02-06 2008-06-25 MEDA Pharma GmbH & Co. KG Nouvelle combinaison d'anticholinergique et de beta-mimetiques pour le traitement de maladies respiratoires
JP2007520509A (ja) * 2004-02-06 2007-07-26 メダ ファーマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディト ゲゼルシャフト 抗コリン薬による、又は抗ヒスタミン薬、ホスホジエステラーゼ４、又はコルチコステロイドとの組み合わせによる鼻炎治療薬
HRP20120286T1 (hr) * 2004-02-06 2012-04-30 Meda Pharma Gmbh & Co. Kg Kombinacija antikolinergika i inhibitora fosfodiesteraze tip 4 za liječenje respiratornih bolesti
WO2005082413A2 (fr) * 2004-02-27 2005-09-09 Altana Pharma Ag Combinaison de ciclesonide et de glycopyrronium
AU2005221151A1 (en) * 2004-03-09 2005-09-22 Arriva Pharmaceuticals, Inc. Treatment of chronic obstructive pulmonary disease by low dose inhalation of protease inhibitor
GB0409703D0 (en) * 2004-04-30 2004-06-02 Vectura Ltd Pharmaceutical compositions
GB0410398D0 (en) * 2004-05-10 2004-06-16 Arakis Ltd The treatment of respiratory disease
GB0410399D0 (en) * 2004-05-10 2004-06-16 Arakis Ltd The treatment of respiratory disease
GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
EP1763344A1 (fr) * 2004-06-29 2007-03-21 Boehringer Ingelheim International GmbH Medicament pour l'inhalation comprenant un steroide et un anticholinergique
EP1616567A1 (fr) * 2004-07-16 2006-01-18 Boehringer Ingelheim Pharma GmbH & Co.KG Médicaments comprenant des inhibiteurs de PDE-IV et des sels de glycopyrolate pour l'inhalation
EP1789018A1 (fr) 2004-08-27 2007-05-30 The Dow Chemical Company Administration amelioree de compositions medicamenteuses pour le traitement d'infections parfois mortelles
US20070105768A1 (en) * 2004-11-10 2007-05-10 Rajiv Nayar Dry recombinant human alpha 1-antitrypsin formulation
GB0425758D0 (en) 2004-11-23 2004-12-22 Vectura Ltd Preparation of pharmaceutical compositions
WO2006087919A1 (fr) * 2005-01-28 2006-08-24 Takeda Pharmaceutical Company Limited Composition finement divisee contenant un substance peu hydrosoluble
CN101128196B (zh) 2005-03-16 2013-01-02 Meda制药有限及两合公司 用于治疗呼吸系统疾病的抗胆碱能药和白三烯受体拮抗剂的组合
EP1861361A1 (fr) * 2005-03-24 2007-12-05 Sosei R&D Ltd. Sels de glycopyrronium et leur application thérapeutique
CA2631492A1 (fr) * 2005-12-15 2007-06-21 Acusphere, Inc. Procedes de preparation de formulations pharmaceutiques a base de particules destinees a une administration orale
DE602006008665D1 (de) 2005-12-21 2009-10-01 Meda Pharma Gmbh & Co Kg Kombination von r,r-glycopyrrolat, rolipram und budesonid zur behandlung von entzündungskrankheiten
GB2434098A (en) * 2005-12-23 2007-07-18 Novartis Ag Process for the preparation of an inhalable dry powder formulation
WO2007109142A2 (fr) * 2006-03-17 2007-09-27 Oregon Health & Science University Antagonistes du recepteur muscarinique m3 pour le traitement des tumeurs exprimant le recepteur muscarinique m3
GB0613161D0 (en) * 2006-06-30 2006-08-09 Novartis Ag Organic Compounds
ES2460576T3 (es) * 2007-12-13 2014-05-13 Novartis Ag Procedimiento para preparar una sustancia farmacológica en partículas y cristalina
JP2011506399A (ja) * 2007-12-13 2011-03-03 ノバルティス アーゲー 有機化合物
GB2468073B (en) * 2008-02-26 2012-09-05 Elevation Pharmaceuticals Inc Method and system for the treatment of chronic obstructive pulmonary disease with nebulized anticholinergic administrations
US20100055045A1 (en) * 2008-02-26 2010-03-04 William Gerhart Method and system for the treatment of chronic obstructive pulmonary disease with nebulized anticholinergic administrations
PL3578169T3 (pl) 2009-02-26 2024-09-02 Glaxo Group Limited Preparaty farmaceutyczne zawierające 4-{(1r)-2-[(6-{2-[(2,6-dichlorobenzylo)oksy]etoksy}heksylo)amino]-1-hydroksyetylo}-2-(hydroksymetylo)fenol
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
SI3106149T1 (sl) * 2009-05-29 2020-07-31 Pearl Therapeutics, Inc. Sestavki za pljučno dostavo muskarinskih antagonistov z dolgotrajnim delovanjem in agonistov beta-2 adrenergičnega receptorja z dolgotrajnim delovanjem in povezani postopki in sistemi
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
CN102665678B (zh) 2009-12-23 2014-07-02 奇斯药制品公司 用于copd的联合治疗
KR101747474B1 (ko) 2009-12-23 2017-06-14 키에시 파르마슈티시 엣스. 피. 에이. Ｃｏｐｄ용 에어로졸 제제
TWI495468B (zh) 2009-12-23 2015-08-11 吉斯藥品公司 治療慢性阻塞性肺病（ｃｏｐｄ）之醫藥組成物
RU2567040C2 (ru) 2009-12-23 2015-10-27 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Аэрозольная препаративная форма для лечения по поводу хронического обструктивного легочного заболевания
JP5877204B2 (ja) 2010-09-29 2016-03-02 パルマトリックス，インコーポレイテッド 吸入用の一価金属カチオン乾燥粉末
JOP20120023B1 (ar) 2011-02-04 2022-03-14 Novartis Ag صياغات مساحيق جافة من جسيمات تحتوي على واحد أو اثنين من المواد الفعالة لعلاج امراض ممرات الهواء الانسدادية او الالتهابية
PT2739268T (pt) 2011-08-01 2019-01-28 Univ Monash Método e formulação para inalação
CN107596518B (zh) 2012-02-29 2021-04-23 普马特里克斯营业公司 可吸入干粉剂
HK1219059A1 (zh) 2013-03-15 2017-03-24 珍珠治疗公司 用於微粒晶体材料的状态调节的方法和系统
WO2014165303A1 (fr) 2013-04-01 2014-10-09 Pulmatrix, Inc. Poudres sèches de tiotropium
US9393202B2 (en) * 2013-04-26 2016-07-19 Chiesi Farmaceutici S.P.A Particle size reduction of an antimuscarinic compound
WO2015094927A1 (fr) * 2013-12-17 2015-06-25 Merck Sharp & Dohme Corp. Procédé de broyage de milieux pour la fabrication de composants pharmaceutiques actifs dans des propulseurs
WO2015101576A1 (fr) 2013-12-30 2015-07-09 Chiesi Farmaceutici S.P.A. Composition de solution d'aérosol stable, mise sous pression, de combinaison de bromure de glycopyrronium et de formotérol
SG11201700536XA (en) 2014-09-09 2017-02-27 Vectura Ltd Formulation comprising glycopyrrolate, method and apparatus
HUE055527T2 (hu) * 2014-09-15 2021-12-28 Verona Pharma Plc RPL554-t tartalmazó folyékony inhalációs készítmény
MA41378A (fr) * 2015-01-20 2017-11-28 Teva Branded Pharmaceutical Prod R & D Inc Inhalateur de poudre sèche comprenant du propionate de fluticasone et du xinafoate de salmétérol
WO2016170518A1 (fr) 2015-04-24 2016-10-27 Glenmark Specialty S.A. Compositions pharmaceutiques comprenant de l'arformotérol et du glycopyrronium
WO2016204998A1 (fr) * 2015-06-15 2016-12-22 Qaam Pharmaceuticals, Llc Sels d'acides gras de glycopyrronium et leurs procédés de production
US9925168B2 (en) 2016-01-22 2018-03-27 Chiesi Farmaceutici S.P.A. Preparation of micronized particles of an antimuscarinic compound by hydrodynamic cavitation
US10098837B2 (en) 2016-07-28 2018-10-16 Chiesi Farmaceutici S.P.A. Combination therapy for COPD
EP4069189A1 (fr) 2019-12-02 2022-10-12 Chiesi Farmaceutici S.p.A. Boîte en acier inoxydable pour inhalateurs doseurs sous pression

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3400197A (en) 1965-01-26 1968-09-03 Robins Co Inc A H Compressible sustained release pharmaceutical tablet lipid-colloidal silica gel matrix fragment granules
US5376386A (en) * 1990-01-24 1994-12-27 British Technology Group Limited Aerosol carriers
US5849263A (en) * 1993-03-30 1998-12-15 Charlotte-Mecklenburg Hospital Authority Pharmaceutical compositions containing alkylaryl polyether alcohol polymer
TW402506B (en) * 1993-06-24 2000-08-21 Astra Ab Therapeutic preparation for inhalation
DE4425255A1 (de) * 1994-07-16 1996-01-18 Asta Medica Ag Formulierung zur inhalativen Applikation
SA95160463B1 (ar) * 1994-12-22 2005-10-04 استرا أكتيبولاج مساحيق للاستنشاق
US5612053A (en) * 1995-04-07 1997-03-18 Edward Mendell Co., Inc. Controlled release insufflation carrier for medicaments
US5690374A (en) * 1996-04-19 1997-11-25 Nor-Easter Enterprises, Inc. Shock-absorbing tool handle
US6613795B2 (en) 1996-11-11 2003-09-02 Christian Noe Enantiomerically pure basic arylcycloalkylhydroxycarboxylic esters, processes for their preparation and their use in medicaments
DK0937041T3 (da) 1996-11-11 2003-08-11 Christian R Noe Anvendelse af et farmaceutisk egnet salt af (3R,2'R)-3-[(cyclopentil-hydroxyphenylacetyl)oxyl]-1,1-dimethyl-pyrrolidinium til fremstilling af et lægemiddel
CA2277801C (fr) * 1997-01-16 2002-10-15 Massachusetts Institute Of Technology Preparation de particules pour inhalation
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
JP2001511160A (ja) * 1997-02-05 2001-08-07 ヤゴ リサーチ アクチェンゲゼルシャフト 医学用エアゾール配合物
US6495167B2 (en) * 1997-03-20 2002-12-17 Schering Corporation Preparation of powder agglomerates
US6585958B1 (en) * 1998-07-24 2003-07-01 Jago Research Ag Medicinal aerosol formulations
AU749697B2 (en) * 1998-08-04 2002-07-04 Jagotec Ag Medicinal aerosol formulations
CA2347856C (fr) * 1998-11-13 2009-02-17 Jagotec Ag Poudre seche pour inhalation
US6406745B1 (en) * 1999-06-07 2002-06-18 Nanosphere, Inc. Methods for coating particles and particles produced thereby
AU7389300A (en) * 1999-08-02 2001-02-19 First Horizon Pharmaceutical Corporation Methods of administration of glycopyrrolate compositions
GB0008660D0 (en) * 2000-04-07 2000-05-31 Arakis Ltd The treatment of respiratory diseases
US6758795B2 (en) 2000-08-22 2004-07-06 Stephen Barber Adjustable water-fillable exercise weights
GB0029903D0 (en) * 2000-12-07 2001-01-24 Arakis Ltd Use of anti-muscarinic agents
GB0410399D0 (en) * 2004-05-10 2004-06-16 Arakis Ltd The treatment of respiratory disease
GB0410398D0 (en) * 2004-05-10 2004-06-16 Arakis Ltd The treatment of respiratory disease
TWI509631B (zh) 2011-02-25 2015-11-21 漢高智慧財產控股公司 用於電子裝置之可燒結銀薄片黏著劑

Also Published As

Publication number Publication date
ES2266242T5 (es) 2016-10-04
US8029768B2 (en) 2011-10-04
NO2015024I1 (no) 2015-11-25
IL151791A (en) 2015-05-31
HK1050846B (en) 2007-01-26
EP1449528A1 (fr) 2004-08-25
NO20024708L (no) 2002-10-24
CA2405705C (fr) 2011-06-07
EP1267866B2 (fr) 2016-07-20
EP1267866A2 (fr) 2003-01-02
NZ535284A (en) 2006-04-28
CN101181263B (zh) 2011-07-06
AU776913B2 (en) 2004-09-23
CY1105120T1 (el) 2010-03-03
WO2001076575A3 (fr) 2002-03-28
NO2015024I2 (no) 2015-11-25
LU92393I2 (fr) 2015-11-02
BR0109875A (pt) 2004-07-20
US20080220073A1 (en) 2008-09-11
AU2004242450A1 (en) 2005-01-20
HUP0301518A2 (hu) 2003-08-28
HU230958B1 (hu) 2019-06-28
DE60120936T3 (de) 2016-11-17
ES2266242T3 (es) 2007-03-01
NZ521476A (en) 2004-10-29
PT1267866E (pt) 2006-10-31
DE60120936D1 (de) 2006-08-03
GB0008660D0 (en) 2000-05-31
WO2001076575A2 (fr) 2001-10-18
CN101181263A (zh) 2008-05-21
EP1449528B1 (fr) 2018-08-08
HK1050846A1 (en) 2003-07-11
MXPA02009718A (es) 2003-05-27
JP5042426B2 (ja) 2012-10-03
AU8930601A (en) 2001-10-23
PL364024A1 (en) 2004-11-29
AU2004242450B2 (en) 2010-06-03
JP2003530344A (ja) 2003-10-14
DK1267866T4 (en) 2016-10-03
NO336142B1 (no) 2015-05-26
AU2010200660B2 (en) 2012-04-19
HUS1900056I1 (hu) 2020-02-28
CN1720995A (zh) 2006-01-18
US20030068280A1 (en) 2003-04-10
EP2193791A1 (fr) 2010-06-09
CA2405705A1 (fr) 2001-10-18
US7229607B2 (en) 2007-06-12
CN1292745C (zh) 2007-01-03
EP1267866B1 (fr) 2006-06-21
DK1267866T3 (da) 2006-10-23
ATE330585T2 (de) 2006-07-15
AU2010200660A1 (en) 2010-03-11
DE60120936T2 (de) 2006-11-02
CN1422154A (zh) 2003-06-04
IL151791A0 (en) 2003-04-10
ES2687751T3 (es) 2018-10-29
NO20024708D0 (no) 2002-10-01
NO2015025I1 (no) 2015-12-07
ZA200207420B (en) 2003-09-16
US20050019271A1 (en) 2005-01-27
BE2013C023I2 (fr) 2020-06-24
US7368104B2 (en) 2008-05-06

Similar Documents

Publication Publication Date Title
LU92166I2 (fr) Glycopyrronium ou un de ses sels
WO2002015662A3 (fr) Fractions heteroaryle substituees par quinuclidine destinees au traitement de maladies
WO2002017358A3 (fr) Fractions heteroaryle substituees par quinuclidine destinees au traitement de maladies
IL187438A0 (en) Pyrrolopyridine derivatives and pharmaceutical compositions containing the same
BR0212042A (pt) Composto, composição farmacêutica, método de tratamento ou prevenção de doenças, e, uso de um composto
WO2005032471A3 (fr) Inhibiteurs de type benzylether et benzylamino de beta-secretase pour le traitement de la maladie d'alzheimer
NO2014009I2 (no) Forbindelser, farmasøytiske sammensetninger og anvendelser derav, samt fremgangsmåte for å fremstille nevnte forbindelser
CY1111693T1 (el) Αντιιικοι παραγοντες
WO2002042462A3 (fr) Agents therapeutiques et methodes d'utilisation de ces agents therapeutiques pour traiter une maladie amyloidogenique
CA2388142A1 (fr) Heterocyles d'azote bicycliques substitue par heteroalkylamino en tant qu'inhibiteurs de la proteine kinase p38
MXPA02011311A (es) Composicion novedosa.
MY138797A (en) Bacterial gyrase inhibitors and uses thereof
BR0316350A (pt) Diaminotriazóis úteis como inibidores de proteìna cinases
DE60219954D1 (de) Neue Indol-2-on Derivate
CL2007000789A1 (es) Compuestos derivados de malonamida, inhibidores de la gamma-secretasa; proceso de preparacion; composicion farmaceutica; y su uso en el tratamiento de la enfermedad de alzheimer.
WO2005051914A8 (fr) Inhibiteurs de benzylether et benzylamino de beta-secretase pour traiter la maladie d'alzheimer
NO20081843L (no) Farmasoytisk sammensetning for forbedret kognitiv funksjon
IL188942A0 (en) Benzimidazole derivatives and pharmaceutical compositions containing the same
MXPA05010496A (es) Moduladores alostericos positivos del receptor de acetilcolina nicotinico.
NO20060149L (no) Farmasoytiske forbindelser av atorvastatin
PT1223972E (pt) Suspensao de uma proteina de epi-hne processo para a sua preparacao aerossol de po anidro derivado dela composicoes farmaceuticas contendo a referida suspensao ou aerossol e as suas utilizacoes
WO2006057945A3 (fr) Derives pyridyle 2,3,4,6-substitues utiles comme inhibiteurs de la beta-secretase pour le traitement de la maladie d'alzheimer
BRPI0417946A (pt) composto, métodos para o tratamento ou a profilaxia de uma doença ou condição, e de distúrbios, e para a indução da cessação do hábito de fumar, composição farmacêutica, e, uso de um composto
CL2004000805A1 (es) Compuestos derivados de 7-aza-quinazolina sustituida, inhibidores de quinasa p38; procedimiento de preparacion; composicion farmaceutica; y su uso para tratar artritis, enfermedad de crohn, alzheimer, asma, ataque al corazon.
BR0105787A (pt) Composição farmacêutica, uso de um composto farmacêutico, método para tratamento de distúrbios, composto farmacêutico e método para confeccionar um composto farmacêutico