WO2004071374A3 - Once a day orally administered pharmaceutical compositions - Google Patents

Once a day orally administered pharmaceutical compositions Download PDF

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Publication number
WO2004071374A3
WO2004071374A3 PCT/IN2004/000018 IN2004000018W WO2004071374A3 WO 2004071374 A3 WO2004071374 A3 WO 2004071374A3 IN 2004000018 W IN2004000018 W IN 2004000018W WO 2004071374 A3 WO2004071374 A3 WO 2004071374A3
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical compositions
once
orally administered
day orally
administered pharmaceutical
Prior art date
Application number
PCT/IN2004/000018
Other languages
French (fr)
Other versions
WO2004071374A2 (en
Inventor
Sunil Sadanand Nadkarni
Original Assignee
Torrent Pharmaceuticals Ltd
Sunil Sadanand Nadkarni
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torrent Pharmaceuticals Ltd, Sunil Sadanand Nadkarni filed Critical Torrent Pharmaceuticals Ltd
Priority to EP04705487A priority Critical patent/EP1596838A2/en
Publication of WO2004071374A2 publication Critical patent/WO2004071374A2/en
Publication of WO2004071374A3 publication Critical patent/WO2004071374A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Abstract

Once a day orally administered pharmaceutical compositions comprising a proton pump inhibitor and a prokinetic agent, the proton pump inhibitor is as delayed release and the prokinetic agent is as sustained release, having improved patient compliance and process of preparing the pharmaceutical compositions.
PCT/IN2004/000018 2003-02-11 2004-01-27 Once a day orally administered pharmaceutical compositions WO2004071374A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP04705487A EP1596838A2 (en) 2003-02-11 2004-01-27 Once a day orally administered pharmaceutical compositions comprising a proton pump inhibitor and a prokinetic agent

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN180/MUM/2003 2003-02-11
IN180MU2003 2003-02-11

Publications (2)

Publication Number Publication Date
WO2004071374A2 WO2004071374A2 (en) 2004-08-26
WO2004071374A3 true WO2004071374A3 (en) 2004-12-16

Family

ID=32866003

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2004/000018 WO2004071374A2 (en) 2003-02-11 2004-01-27 Once a day orally administered pharmaceutical compositions

Country Status (2)

Country Link
EP (1) EP1596838A2 (en)
WO (1) WO2004071374A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7064683B2 (en) 2017-01-27 2022-05-11 日本ケミファ株式会社 Composition for preventing damage to the enteric layer

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004071374A2 (en) * 2003-02-11 2004-08-26 Torrent Pharmaceuticals Limited Once a day orally administered pharmaceutical compositions
EP1729743A1 (en) * 2004-01-06 2006-12-13 Panacea Biotec Limited Pharmaceutical compositions comprising a proton pump inhibitor and a prokinetic agent
KR101276571B1 (en) * 2004-09-02 2013-06-18 얀센 파마슈티카 엔.브이. Furamate of 4-((4-(4-(2-cyanoethenyl)-2,6-dimethylphenyl)amino)-2-pyrimidinyl)amino)benzonitrile
AR052225A1 (en) * 2004-11-04 2007-03-07 Astrazeneca Ab FORMULATIONS OF MODIFIED RELEASE TABLETS FOR INHIBITORS OF THE PUMP OF PROTONS
AR051654A1 (en) * 2004-11-04 2007-01-31 Astrazeneca Ab NEW FORMULATIONS OF MODIFIED RELEASE PELLETS FOR PROTON PUMP INHIBITORS
GB0613310D0 (en) * 2006-07-05 2006-08-16 Merck Sharp & Dohme The use of pvp to control the release profile of an active ingredient from a hydrophilic polymer matrix tablet
WO2010038241A2 (en) * 2008-09-30 2010-04-08 Panacea Biotec Limited Pharmaceutical compositions comprising of proton pump inhibitor, prokinetic agent and alginic acid
US8784884B2 (en) 2009-09-17 2014-07-22 Stephen Perrett Pancreatic enzyme compositions and methods for treating pancreatitis and pancreatic insufficiency
KR101246553B1 (en) * 2010-04-09 2013-03-26 현대약품 주식회사 Sustained-release composition and process for producing the same
EP2563341A1 (en) * 2010-04-26 2013-03-06 Mahmut Bilgic Pharmaceutical compositions inducing synergistic effect
BRPI1103093A2 (en) * 2011-06-03 2013-07-02 Eurofarma Laboratarios Ltda oral pharmaceutical composition and use of the oral pharmaceutical composition
CN102319181B (en) * 2011-09-08 2014-07-16 广东大华农动物保健品股份有限公司 Enveloping process for micro-capsule animal medicament
JP2015522653A (en) * 2012-07-26 2015-08-06 ルピン・リミテッドＬｕｐｉｎ Ｌｉｍｉｔｅｄ Pharmaceutical composition of proton pump inhibitor
MX2017001714A (en) * 2017-02-07 2018-08-06 Rhein Siegfried Sa De Cv Rapid-release composition of cinitapride and simeticone and method for preparing same.
KR101941511B1 (en) * 2017-09-12 2019-01-24 한국유나이티드제약 주식회사 Sustained-release formulation comprising itopride having a broad molecular weight distribution
TR201723047A2 (en) * 2017-12-29 2019-07-22 Neutec Ar Ge Sanayi Ve Ticaret Anonim Sirketi Pharmaceutical composition comprising a proton pump inhibitor and prukaloprid.
CN109394711A (en) * 2018-11-06 2019-03-01 威海贯标信息科技有限公司 A kind of cinbitrate tartrate tablet composition
CN110934853B (en) * 2019-12-30 2023-06-23 鲁南制药集团股份有限公司 Mosapride citrate sustained-release pellet capsule and preparation method thereof
KR102497608B1 (en) * 2020-04-27 2023-02-08 한국유나이티드제약 주식회사 Fixed Dose Combination Comprising Mosapride and Proton Pump Inhibitor

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5330982A (en) * 1986-12-17 1994-07-19 Glaxo Group Limited Pharmaceutical composition containing a 5-HT receptor antagonist and an H+ K+ Atpase inhibitor and a method of treating gastrointestingal disorders therewith
WO1997025065A1 (en) * 1996-01-08 1997-07-17 Astra Aktiebolag Oral pharmaceutical dosage forms comprising a proton pump inhibitor and a prokinetic agent
WO2000051583A2 (en) * 1999-03-02 2000-09-08 Sepracor Inc. Methods and compositions using (+) norcisapride in combination with proton pump inhibitors or h2 receptor antagonists
WO2004071374A2 (en) * 2003-02-11 2004-08-26 Torrent Pharmaceuticals Limited Once a day orally administered pharmaceutical compositions

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5330982A (en) * 1986-12-17 1994-07-19 Glaxo Group Limited Pharmaceutical composition containing a 5-HT receptor antagonist and an H+ K+ Atpase inhibitor and a method of treating gastrointestingal disorders therewith
WO1997025065A1 (en) * 1996-01-08 1997-07-17 Astra Aktiebolag Oral pharmaceutical dosage forms comprising a proton pump inhibitor and a prokinetic agent
WO2000051583A2 (en) * 1999-03-02 2000-09-08 Sepracor Inc. Methods and compositions using (+) norcisapride in combination with proton pump inhibitors or h2 receptor antagonists
WO2004071374A2 (en) * 2003-02-11 2004-08-26 Torrent Pharmaceuticals Limited Once a day orally administered pharmaceutical compositions

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7064683B2 (en) 2017-01-27 2022-05-11 日本ケミファ株式会社 Composition for preventing damage to the enteric layer

Also Published As

Publication number Publication date
WO2004071374A2 (en) 2004-08-26
EP1596838A2 (en) 2005-11-23

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