HU228341B1 - Stable complexes of poorly soluble compounds - Google Patents

Stable complexes of poorly soluble compounds Download PDF

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Publication number
HU228341B1
HU228341B1 HU9903189A HUP9903189A HU228341B1 HU 228341 B1 HU228341 B1 HU 228341B1 HU 9903189 A HU9903189 A HU 9903189A HU P9903189 A HUP9903189 A HU P9903189A HU 228341 B1 HU228341 B1 HU 228341B1
Authority
HU
Hungary
Prior art keywords
compound
polymer
complex
anionic polymer
insoluble
Prior art date
Application number
HU9903189A
Other languages
English (en)
Hungarian (hu)
Inventor
Navnit Hargovindas Shah
Antiono A Albano
Wantanee Phuapradit
Harpreet K Sandhu
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26798138&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HU228341(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HU9903189D0 publication Critical patent/HU9903189D0/hu
Publication of HUP9903189A2 publication Critical patent/HUP9903189A2/hu
Publication of HUP9903189A3 publication Critical patent/HUP9903189A3/hu
Publication of HU228341B1 publication Critical patent/HU228341B1/hu

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU9903189A 1998-09-22 1999-09-20 Stable complexes of poorly soluble compounds HU228341B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10133698P 1998-09-22 1998-09-22
US13653199P 1999-05-28 1999-05-28

Publications (4)

Publication Number Publication Date
HU9903189D0 HU9903189D0 (en) 1999-11-29
HUP9903189A2 HUP9903189A2 (hu) 2000-06-28
HUP9903189A3 HUP9903189A3 (en) 2009-07-28
HU228341B1 true HU228341B1 (en) 2013-03-28

Family

ID=26798138

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9903189A HU228341B1 (en) 1998-09-22 1999-09-20 Stable complexes of poorly soluble compounds

Country Status (32)

Country Link
US (1) US6350786B1 (cg-RX-API-DMAC10.html)
EP (1) EP0988863B2 (cg-RX-API-DMAC10.html)
JP (5) JP2000095708A (cg-RX-API-DMAC10.html)
KR (1) KR100362019B1 (cg-RX-API-DMAC10.html)
CN (1) CN1201821C (cg-RX-API-DMAC10.html)
AR (2) AR022096A1 (cg-RX-API-DMAC10.html)
AT (1) ATE265232T1 (cg-RX-API-DMAC10.html)
AU (1) AU770745B2 (cg-RX-API-DMAC10.html)
BR (1) BR9904283A (cg-RX-API-DMAC10.html)
CA (1) CA2282906C (cg-RX-API-DMAC10.html)
CO (1) CO5140077A1 (cg-RX-API-DMAC10.html)
CZ (1) CZ300215B6 (cg-RX-API-DMAC10.html)
DE (1) DE69916733T3 (cg-RX-API-DMAC10.html)
DK (1) DK0988863T4 (cg-RX-API-DMAC10.html)
ES (1) ES2218918T5 (cg-RX-API-DMAC10.html)
HR (1) HRP990287B1 (cg-RX-API-DMAC10.html)
HU (1) HU228341B1 (cg-RX-API-DMAC10.html)
ID (1) ID24034A (cg-RX-API-DMAC10.html)
IL (1) IL131957A (cg-RX-API-DMAC10.html)
MA (1) MA26692A1 (cg-RX-API-DMAC10.html)
MY (1) MY124377A (cg-RX-API-DMAC10.html)
NO (1) NO326928B1 (cg-RX-API-DMAC10.html)
NZ (1) NZ337884A (cg-RX-API-DMAC10.html)
PE (1) PE20001049A1 (cg-RX-API-DMAC10.html)
PL (1) PL202757B1 (cg-RX-API-DMAC10.html)
PT (1) PT988863E (cg-RX-API-DMAC10.html)
RS (1) RS50193B (cg-RX-API-DMAC10.html)
RU (1) RU2240827C2 (cg-RX-API-DMAC10.html)
SG (1) SG97131A1 (cg-RX-API-DMAC10.html)
SI (1) SI0988863T2 (cg-RX-API-DMAC10.html)
TR (1) TR199902324A2 (cg-RX-API-DMAC10.html)
TW (1) TWI234465B (cg-RX-API-DMAC10.html)

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JP2015187170A (ja) 2015-10-29
HRP990287B1 (en) 2004-12-31
ID24034A (id) 2000-07-06
CZ330499A3 (cs) 2000-04-12
SI0988863T2 (sl) 2009-08-31
MA26692A1 (fr) 2004-12-20
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EP0988863B2 (en) 2009-03-18
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DE69916733T3 (de) 2009-09-24
YU47399A (cg-RX-API-DMAC10.html) 2002-08-12
IL131957A (en) 2005-06-19
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