EP0952770A4 - System for rendering substantially non-dissoluble bio-affecting agents bio-available - Google Patents

System for rendering substantially non-dissoluble bio-affecting agents bio-available

Info

Publication number
EP0952770A4
EP0952770A4 EP96932188A EP96932188A EP0952770A4 EP 0952770 A4 EP0952770 A4 EP 0952770A4 EP 96932188 A EP96932188 A EP 96932188A EP 96932188 A EP96932188 A EP 96932188A EP 0952770 A4 EP0952770 A4 EP 0952770A4
Authority
EP
European Patent Office
Prior art keywords
bio
dissoluble
available
substantially non
affecting agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96932188A
Other languages
German (de)
French (fr)
Other versions
EP0952770A1 (en
Inventor
Steven Frisbee
Garry L Myers
Richard C Fuisz
Andrea Blake
Robert K Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biovail Technologies Ltd
Original Assignee
Fuisz Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fuisz Technologies Ltd filed Critical Fuisz Technologies Ltd
Publication of EP0952770A1 publication Critical patent/EP0952770A1/en
Publication of EP0952770A4 publication Critical patent/EP0952770A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10—Macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
EP96932188A 1995-09-07 1996-09-09 System for rendering substantially non-dissoluble bio-affecting agents bio-available Withdrawn EP0952770A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52453195A 1995-09-07 1995-09-07
US524531 1995-09-07
PCT/US1996/014457 WO1997008950A1 (en) 1995-09-07 1996-09-09 System for rendering substantially non-dissoluble bio-affecting agents bio-available

Publications (2)

Publication Number Publication Date
EP0952770A1 EP0952770A1 (en) 1999-11-03
EP0952770A4 true EP0952770A4 (en) 1999-12-22

Family

ID=24089609

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96932188A Withdrawn EP0952770A4 (en) 1995-09-07 1996-09-09 System for rendering substantially non-dissoluble bio-affecting agents bio-available

Country Status (5)

Country Link
EP (1) EP0952770A4 (en)
JP (1) JPH11514979A (en)
AU (1) AU7106996A (en)
CA (1) CA2231050A1 (en)
WO (1) WO1997008950A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6013280A (en) * 1997-10-07 2000-01-11 Fuisz Technologies Ltd. Immediate release dosage forms containing microspheres
KR20000069356A (en) * 1997-10-07 2000-11-25 리차드 디. 슈미트 Immediate Release Drug Delivery forms
US6350786B1 (en) * 1998-09-22 2002-02-26 Hoffmann-La Roche Inc. Stable complexes of poorly soluble compounds in ionic polymers
FR2795326B1 (en) † 1999-06-28 2001-08-31 Adir SOLID THERMOFORMABLE PHARMACEUTICAL COMPOSITION WITH CONTROLLED RELEASE
JP2001247408A (en) * 2000-03-08 2001-09-11 Hodogaya Chem Co Ltd Feeding type insect pest-controlling composition using acid-soluble polymer
FR2818552B1 (en) * 2000-12-26 2003-02-07 Servier Lab SOLID THERMOFORMABLE PHARMACEUTICAL COMPOSITIONS FOR THE CONTROLLED RELEASE OF IVABRADINE
CA2450957A1 (en) 2001-06-22 2003-01-03 Pfizer Products Inc. Pharmaceutical compositions of dispersions of drugs and neutral polymers
US9808471B2 (en) 2003-04-16 2017-11-07 Mylan Specialty Lp Nasal pharmaceutical formulations and methods of using the same
US8912174B2 (en) 2003-04-16 2014-12-16 Mylan Pharmaceuticals Inc. Formulations and methods for treating rhinosinusitis
US7811606B2 (en) 2003-04-16 2010-10-12 Dey, L.P. Nasal pharmaceutical formulations and methods of using the same
NZ549792A (en) * 2004-03-10 2009-12-24 Bayer Schering Pharma Ag Compositions comprising drospirenone molecularly dispersed
WO2005117834A1 (en) * 2004-05-27 2005-12-15 Janssen Pharmaceutica N.V. Solid dispersions of a basic drug compound and a polymer containing acidic groups
JP5508003B2 (en) * 2006-06-30 2014-05-28 アイスイティカ ピーティーワイ リミテッド Process for the preparation of biologically active compounds in nanoparticulate form
JO3002B1 (en) 2009-08-28 2016-09-05 Irm Llc Compounds and compositions as protein kinase inhibitors
JP5953646B2 (en) * 2009-11-24 2016-07-20 大正製薬株式会社 Solid formulation containing ibuprofen
PE20141994A1 (en) 2011-11-23 2014-12-24 Novartis Ag PHARMACEUTICAL FORMULATIONS

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0240904A2 (en) * 1986-04-11 1987-10-14 BASF Aktiengesellschaft Process for the preparation of solid pharmaceutical forms
WO1993011750A1 (en) * 1991-12-17 1993-06-24 Fuisz Technologies Ltd. Ulcer prevention and treatment composition and method
WO1993013773A1 (en) * 1992-01-13 1993-07-22 Ethical Pharmaceuticals Limited Pharmaceutical compositions containing nifedipine and process for the preparation thereof
WO1993024154A1 (en) * 1992-06-03 1993-12-09 Fuisz Technologies, Ltd. Biodegradable controlled release melt-spun delivery system
JPH08291063A (en) * 1995-04-21 1996-11-05 Maruho Kk Readily absorbable pharmaceutical preparation and its production

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3146167A (en) * 1961-10-05 1964-08-25 Smith Kline French Lab Method of preparing sustained release pellets and products thereof
US3829564A (en) * 1970-07-17 1974-08-13 Commw Scient Ind Res Org Coated products for veterinary use
US4755397A (en) * 1986-12-24 1988-07-05 National Starch And Chemical Corporation Starch based particulate encapsulation process
FR2634397B2 (en) * 1986-12-31 1991-04-19 Centre Nat Rech Scient PROCESS FOR THE PREPARATION OF DISPERSIBLE COLLOIDAL SYSTEMS OF A PROTEIN IN THE FORM OF NANOPARTICLES
US4855326A (en) * 1987-04-20 1989-08-08 Fuisz Pharmaceutical Ltd. Rapidly dissoluble medicinal dosage unit and method of manufacture
US4948586A (en) * 1987-11-02 1990-08-14 Lim Technology Laboratories, Inc. Microencapsulated insecticidal pathogens

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0240904A2 (en) * 1986-04-11 1987-10-14 BASF Aktiengesellschaft Process for the preparation of solid pharmaceutical forms
WO1993011750A1 (en) * 1991-12-17 1993-06-24 Fuisz Technologies Ltd. Ulcer prevention and treatment composition and method
WO1993013773A1 (en) * 1992-01-13 1993-07-22 Ethical Pharmaceuticals Limited Pharmaceutical compositions containing nifedipine and process for the preparation thereof
WO1993024154A1 (en) * 1992-06-03 1993-12-09 Fuisz Technologies, Ltd. Biodegradable controlled release melt-spun delivery system
JPH08291063A (en) * 1995-04-21 1996-11-05 Maruho Kk Readily absorbable pharmaceutical preparation and its production

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 1997, no. 03 31 March 1997 (1997-03-31) *
See also references of WO9708950A1 *

Also Published As

Publication number Publication date
JPH11514979A (en) 1999-12-21
AU7106996A (en) 1997-03-27
WO1997008950A1 (en) 1997-03-13
EP0952770A1 (en) 1999-11-03
CA2231050A1 (en) 1997-03-13

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Owner name: BIOVAIL TECHNOLOGIES LTD.

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Effective date: 20010412

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