HU188802B - Process for preparing trans-2-substituted-5-aryl-2,3,4, 4a,5,9b-hexahydro-1h-pyrido/4,3-b/indole derivatives - Google Patents

Process for preparing trans-2-substituted-5-aryl-2,3,4, 4a,5,9b-hexahydro-1h-pyrido/4,3-b/indole derivatives Download PDF

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Publication number
HU188802B
HU188802B HU822638A HU822638A HU188802B HU 188802 B HU188802 B HU 188802B HU 822638 A HU822638 A HU 822638A HU 822638 A HU822638 A HU 822638A HU 188802 B HU188802 B HU 188802B
Authority
HU
Hungary
Prior art keywords
trans
hexahydro
formula
pyrido
hydrogen
Prior art date
Application number
HU822638A
Other languages
German (de)
English (en)
Hungarian (hu)
Inventor
Willard M Welch
Original Assignee
Pfizer Inc,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc,Us filed Critical Pfizer Inc,Us
Publication of HU188802B publication Critical patent/HU188802B/hu

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU822638A 1977-05-23 1978-05-18 Process for preparing trans-2-substituted-5-aryl-2,3,4, 4a,5,9b-hexahydro-1h-pyrido/4,3-b/indole derivatives HU188802B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79939277A 1977-05-23 1977-05-23

Publications (1)

Publication Number Publication Date
HU188802B true HU188802B (en) 1986-05-28

Family

ID=25175793

Family Applications (3)

Application Number Title Priority Date Filing Date
HU822639A HU187782B (en) 1977-05-23 1978-05-18 Process for preparing trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido-/4,3-b/indole derivatives
HU822638A HU188802B (en) 1977-05-23 1978-05-18 Process for preparing trans-2-substituted-5-aryl-2,3,4, 4a,5,9b-hexahydro-1h-pyrido/4,3-b/indole derivatives
HU78PI626A HU185009B (en) 1977-05-23 1978-05-18 Process for preparing trans-2-substituted-5-aryl-2,3,4,4a,5,9b,- hexahydro-1h-pyrido/4,3-b/ indole derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HU822639A HU187782B (en) 1977-05-23 1978-05-18 Process for preparing trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido-/4,3-b/indole derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU78PI626A HU185009B (en) 1977-05-23 1978-05-18 Process for preparing trans-2-substituted-5-aryl-2,3,4,4a,5,9b,- hexahydro-1h-pyrido/4,3-b/ indole derivatives

Country Status (31)

Country Link
JP (1) JPS53144600A (fr)
AR (2) AR217688A1 (fr)
AT (1) AT368995B (fr)
AU (1) AU499618B1 (fr)
BE (1) BE867249A (fr)
CA (1) CA1094071A (fr)
CH (1) CH634321A5 (fr)
CS (1) CS207612B2 (fr)
DD (4) DD145536A5 (fr)
DE (1) DE2822465C2 (fr)
DK (1) DK226678A (fr)
EG (1) EG13590A (fr)
FI (1) FI63402C (fr)
FR (1) FR2392023A1 (fr)
GB (1) GB1586655A (fr)
GR (1) GR69985B (fr)
HU (3) HU187782B (fr)
IE (1) IE46975B1 (fr)
IL (1) IL54755A (fr)
IT (1) IT1096307B (fr)
LU (1) LU79684A1 (fr)
NL (1) NL7804210A (fr)
NO (2) NO150204C (fr)
NZ (1) NZ187333A (fr)
PH (1) PH13756A (fr)
PL (5) PL117107B1 (fr)
PT (1) PT68058B (fr)
SE (2) SE441448B (fr)
SU (4) SU873883A3 (fr)
YU (4) YU91478A (fr)
ZA (1) ZA782918B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4451655A (en) * 1982-05-17 1984-05-29 Pfizer Inc. Process for preparing carboline derivatives and compounds used in their preparation
RU2106864C1 (ru) * 1995-10-23 1998-03-20 Николай Серафимович Зефиров Средство для лечения болезни альцгеймера
SE9604786D0 (sv) * 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
US6974825B1 (en) 1996-12-20 2005-12-13 Astrazeneca Canada Inc. Compounds with analgesic effect
SE9904675D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0101773D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101769D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101771D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101770D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
DE20204239U1 (de) 2002-03-16 2002-05-29 Funke Kunststoffe GmbH, 48324 Sendenhorst Universal-Rohrdichtung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205452A1 (es) * 1973-12-06 1976-05-07 Endo Lab Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles
JPS50126699A (fr) * 1974-03-20 1975-10-04
US4001263A (en) * 1974-04-01 1977-01-04 Pfizer Inc. 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines

Also Published As

Publication number Publication date
JPS53144600A (en) 1978-12-15
YU221882A (en) 1983-01-21
NO151862C (no) 1985-06-19
NO151862B (no) 1985-03-11
DD145536A5 (de) 1980-12-17
BE867249A (fr) 1978-11-20
AT368995B (de) 1982-11-25
HU185009B (en) 1984-11-28
SE441448B (sv) 1985-10-07
DD145537A5 (de) 1980-12-17
CH634321A5 (en) 1983-01-31
SU873883A3 (ru) 1981-10-15
NO781770L (no) 1978-11-24
DE2822465C2 (de) 1986-08-28
IL54755A0 (en) 1978-07-31
PL114541B1 (en) 1981-02-28
SU843749A3 (ru) 1981-06-30
NO150204B (no) 1984-05-28
PH13756A (en) 1980-09-17
DE2822465A1 (de) 1978-11-30
NO150204C (no) 1984-09-05
PT68058B (en) 1979-10-24
DK226678A (da) 1978-11-24
YU91478A (en) 1983-01-21
AR221721A1 (es) 1981-03-13
PL117107B1 (en) 1981-07-31
PT68058A (en) 1978-06-01
SE8305917L (sv) 1983-10-27
GR69985B (fr) 1982-07-22
NO831790L (no) 1978-11-24
FI63402C (fi) 1983-06-10
SE448459B (sv) 1987-02-23
IT1096307B (it) 1985-08-26
PL116944B1 (en) 1981-07-31
JPS5711912B2 (fr) 1982-03-08
SU818484A3 (ru) 1981-03-30
PL206903A1 (pl) 1979-10-22
SE7803625L (sv) 1978-11-24
NL7804210A (nl) 1978-11-27
CS207612B2 (en) 1981-08-31
IE46975B1 (en) 1983-11-16
AU499618B1 (en) 1979-04-26
ATA369678A (de) 1982-04-15
DD138321A5 (de) 1979-10-24
FI63402B (fi) 1983-02-28
YU40796B (en) 1986-06-30
CA1094071A (fr) 1981-01-20
NZ187333A (en) 1984-05-31
PL114547B1 (en) 1981-02-28
IE781013L (en) 1978-11-23
YU221782A (en) 1983-01-21
FI781612A (fi) 1978-11-24
FR2392023B1 (fr) 1980-11-07
AR217688A1 (es) 1980-04-15
EG13590A (en) 1982-03-31
SE8305917D0 (sv) 1983-10-27
SU841589A3 (ru) 1981-06-23
GB1586655A (en) 1981-03-25
FR2392023A1 (fr) 1978-12-22
ZA782918B (en) 1979-06-27
DD146186A5 (de) 1981-01-28
LU79684A1 (fr) 1979-12-06
YU221682A (en) 1983-01-21
IT7823673A0 (it) 1978-05-22
HU187782B (en) 1986-02-28
IL54755A (en) 1981-02-27

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