IE781013L - Pyrido-indole tranquilisers - Google Patents
Pyrido-indole tranquilisersInfo
- Publication number
- IE781013L IE781013L IE781013A IE101378A IE781013L IE 781013 L IE781013 L IE 781013L IE 781013 A IE781013 A IE 781013A IE 101378 A IE101378 A IE 101378A IE 781013 L IE781013 L IE 781013L
- Authority
- IE
- Ireland
- Prior art keywords
- pyrido
- salts
- compounds
- tranquilisers
- indole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Psychiatry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
5-Phenyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles, which are substituted in position 2, and their salts of formula I, the symbols of which are explained in Claim 1, are described. These compounds and their salts are therapeutically active and can be used as medicaments for controlling schizophrenic symptoms. The pharmaceutical compositions are also described. The new compounds and their salts can be obtained by processes which are especially distinguished from others by the formation of the substituent in position 2; the latter is obtained by processes which each contain a reduction stage, from compounds which already have the pyridoindole system. <IMAGE>
[GB1586655A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79939277A | 1977-05-23 | 1977-05-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE781013L true IE781013L (en) | 1978-11-23 |
| IE46975B1 IE46975B1 (en) | 1983-11-16 |
Family
ID=25175793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1013/78A IE46975B1 (en) | 1977-05-23 | 1978-05-22 | Pyrido-indole tranquilising agents |
Country Status (31)
| Country | Link |
|---|---|
| JP (1) | JPS53144600A (en) |
| AR (2) | AR217688A1 (en) |
| AT (1) | AT368995B (en) |
| AU (1) | AU499618B1 (en) |
| BE (1) | BE867249A (en) |
| CA (1) | CA1094071A (en) |
| CH (1) | CH634321A5 (en) |
| CS (1) | CS207612B2 (en) |
| DD (4) | DD145537A5 (en) |
| DE (1) | DE2822465C2 (en) |
| DK (1) | DK226678A (en) |
| EG (1) | EG13590A (en) |
| FI (1) | FI63402C (en) |
| FR (1) | FR2392023A1 (en) |
| GB (1) | GB1586655A (en) |
| GR (1) | GR69985B (en) |
| HU (3) | HU188802B (en) |
| IE (1) | IE46975B1 (en) |
| IL (1) | IL54755A (en) |
| IT (1) | IT1096307B (en) |
| LU (1) | LU79684A1 (en) |
| NL (1) | NL7804210A (en) |
| NO (2) | NO150204C (en) |
| NZ (1) | NZ187333A (en) |
| PH (1) | PH13756A (en) |
| PL (5) | PL114541B1 (en) |
| PT (1) | PT68058B (en) |
| SE (2) | SE441448B (en) |
| SU (4) | SU873883A3 (en) |
| YU (4) | YU91478A (en) |
| ZA (1) | ZA782918B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4224329A (en) * | 1979-01-23 | 1980-09-23 | Pfizer Inc. | 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles |
| US4451655A (en) * | 1982-05-17 | 1984-05-29 | Pfizer Inc. | Process for preparing carboline derivatives and compounds used in their preparation |
| RU2106864C1 (en) * | 1995-10-23 | 1998-03-20 | Николай Серафимович Зефиров | New approach to treatment of alzheimer's disease |
| SE9604786D0 (en) * | 1996-12-20 | 1996-12-20 | Astra Pharma Inc | New compounds |
| US6974825B1 (en) | 1996-12-20 | 2005-12-13 | Astrazeneca Canada Inc. | Compounds with analgesic effect |
| SE9904675D0 (en) | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
| SE0101771D0 (en) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101769D0 (en) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101773D0 (en) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101770D0 (en) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR205452A1 (en) * | 1973-12-06 | 1976-05-07 | Endo Lab | METHOD TO PREPARE NEW TRANS-2, 3, 4, 4A, 5, 9B-HEXAHYDRO-5-PHENYL-1H-PYRID (4,3-B) INDOLES |
| JPS50126699A (en) * | 1974-03-20 | 1975-10-04 | ||
| US4001263A (en) * | 1974-04-01 | 1977-01-04 | Pfizer Inc. | 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines |
-
1978
- 1978-03-30 SE SE7803625A patent/SE441448B/en unknown
- 1978-04-17 PH PH21013A patent/PH13756A/en unknown
- 1978-04-18 YU YU00914/78A patent/YU91478A/en unknown
- 1978-04-20 NL NL7804210A patent/NL7804210A/en not_active Application Discontinuation
- 1978-04-24 AU AU35377/78A patent/AU499618B1/en not_active Expired
- 1978-04-25 EG EG276/78A patent/EG13590A/en active
- 1978-04-28 AR AR271956A patent/AR217688A1/en active
- 1978-05-18 PL PL1978215922A patent/PL114541B1/en unknown
- 1978-05-18 PL PL1978206903A patent/PL114547B1/en unknown
- 1978-05-18 HU HU822638A patent/HU188802B/en unknown
- 1978-05-18 HU HU78PI626A patent/HU185009B/en unknown
- 1978-05-18 PL PL1978215923A patent/PL116944B1/en unknown
- 1978-05-18 PL PL1978215921A patent/PL117107B1/en unknown
- 1978-05-18 HU HU822639A patent/HU187782B/en unknown
- 1978-05-18 GB GB20350/78A patent/GB1586655A/en not_active Expired
- 1978-05-18 CS CS783239A patent/CS207612B2/en unknown
- 1978-05-18 SU SU782615898A patent/SU873883A3/en active
- 1978-05-19 DD DD78215017A patent/DD145537A5/en unknown
- 1978-05-19 DD DD215016A patent/DD146186A5/en unknown
- 1978-05-19 DD DD78205479A patent/DD138321A5/en unknown
- 1978-05-19 DD DD78215015A patent/DD145536A5/en unknown
- 1978-05-19 CA CA303,710A patent/CA1094071A/en not_active Expired
- 1978-05-19 BE BE187842A patent/BE867249A/en not_active IP Right Cessation
- 1978-05-19 PT PT68058A patent/PT68058B/en unknown
- 1978-05-20 GR GR56281A patent/GR69985B/el unknown
- 1978-05-22 NZ NZ187333A patent/NZ187333A/en unknown
- 1978-05-22 NO NO781770A patent/NO150204C/en unknown
- 1978-05-22 IT IT23673/78A patent/IT1096307B/en active
- 1978-05-22 IL IL54755A patent/IL54755A/en unknown
- 1978-05-22 DK DK226678A patent/DK226678A/en not_active Application Discontinuation
- 1978-05-22 JP JP6087278A patent/JPS53144600A/en active Granted
- 1978-05-22 LU LU79684A patent/LU79684A1/en unknown
- 1978-05-22 FI FI781612A patent/FI63402C/en not_active IP Right Cessation
- 1978-05-22 AT AT0369678A patent/AT368995B/en not_active IP Right Cessation
- 1978-05-22 ZA ZA00782918A patent/ZA782918B/en unknown
- 1978-05-22 FR FR7815029A patent/FR2392023A1/en active Granted
- 1978-05-22 CH CH552678A patent/CH634321A5/en not_active IP Right Cessation
- 1978-05-22 IE IE1013/78A patent/IE46975B1/en unknown
- 1978-05-23 DE DE2822465A patent/DE2822465C2/en not_active Expired
-
1979
- 1979-04-16 AR AR276191A patent/AR221721A1/en active
- 1979-04-24 SU SU792753359A patent/SU843749A3/en active
- 1979-04-26 SU SU792759902A patent/SU818484A3/en active
- 1979-05-18 PL PL20690379A patent/PL206903A1/en unknown
- 1979-05-18 SU SU792763595A patent/SU841589A3/en active
-
1982
- 1982-10-01 YU YU02216/82A patent/YU221682A/en unknown
- 1982-10-01 YU YU2217/82A patent/YU40796B/en unknown
- 1982-10-01 YU YU02218/82A patent/YU221882A/en unknown
-
1983
- 1983-05-20 NO NO831790A patent/NO151862C/en unknown
- 1983-10-27 SE SE8305917A patent/SE448459B/en not_active IP Right Cessation
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