SU873883A3 - Способ получени гексагидро - -карболинов или их солей - Google Patents

Способ получени гексагидро - -карболинов или их солей Download PDF

Info

Publication number
SU873883A3
SU873883A3 SU782615898A SU2615898A SU873883A3 SU 873883 A3 SU873883 A3 SU 873883A3 SU 782615898 A SU782615898 A SU 782615898A SU 2615898 A SU2615898 A SU 2615898A SU 873883 A3 SU873883 A3 SU 873883A3
Authority
SU
USSR - Soviet Union
Prior art keywords
fluorophenyl
acid
resulting
fluoro
salts
Prior art date
Application number
SU782615898A
Other languages
English (en)
Russian (ru)
Inventor
МакКован Велч Виллард (младший)
Original Assignee
Пфайзер Инк(Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Инк(Фирма) filed Critical Пфайзер Инк(Фирма)
Application granted granted Critical
Publication of SU873883A3 publication Critical patent/SU873883A3/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SU782615898A 1977-05-23 1978-05-18 Способ получени гексагидро - -карболинов или их солей SU873883A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79939277A 1977-05-23 1977-05-23

Publications (1)

Publication Number Publication Date
SU873883A3 true SU873883A3 (ru) 1981-10-15

Family

ID=25175793

Family Applications (4)

Application Number Title Priority Date Filing Date
SU782615898A SU873883A3 (ru) 1977-05-23 1978-05-18 Способ получени гексагидро - -карболинов или их солей
SU792753359A SU843749A3 (ru) 1977-05-23 1979-04-24 Способ получени 4а,9в-транс- гЕКСАгидРО- -КАРбОлиНА
SU792759902A SU818484A3 (ru) 1977-05-23 1979-04-26 Способ получени 4а, 9 -транс-гЕКСАгидРО - -КАРбОлиНА
SU792763595A SU841589A3 (ru) 1977-05-23 1979-05-18 Способ получени гексагидро- - КАРбОлиНОВ или иХ СОлЕй

Family Applications After (3)

Application Number Title Priority Date Filing Date
SU792753359A SU843749A3 (ru) 1977-05-23 1979-04-24 Способ получени 4а,9в-транс- гЕКСАгидРО- -КАРбОлиНА
SU792759902A SU818484A3 (ru) 1977-05-23 1979-04-26 Способ получени 4а, 9 -транс-гЕКСАгидРО - -КАРбОлиНА
SU792763595A SU841589A3 (ru) 1977-05-23 1979-05-18 Способ получени гексагидро- - КАРбОлиНОВ или иХ СОлЕй

Country Status (31)

Country Link
JP (1) JPS53144600A (fr)
AR (2) AR217688A1 (fr)
AT (1) AT368995B (fr)
AU (1) AU499618B1 (fr)
BE (1) BE867249A (fr)
CA (1) CA1094071A (fr)
CH (1) CH634321A5 (fr)
CS (1) CS207612B2 (fr)
DD (4) DD146186A5 (fr)
DE (1) DE2822465C2 (fr)
DK (1) DK226678A (fr)
EG (1) EG13590A (fr)
FI (1) FI63402C (fr)
FR (1) FR2392023A1 (fr)
GB (1) GB1586655A (fr)
GR (1) GR69985B (fr)
HU (3) HU185009B (fr)
IE (1) IE46975B1 (fr)
IL (1) IL54755A (fr)
IT (1) IT1096307B (fr)
LU (1) LU79684A1 (fr)
NL (1) NL7804210A (fr)
NO (2) NO150204C (fr)
NZ (1) NZ187333A (fr)
PH (1) PH13756A (fr)
PL (5) PL114547B1 (fr)
PT (1) PT68058B (fr)
SE (2) SE441448B (fr)
SU (4) SU873883A3 (fr)
YU (4) YU91478A (fr)
ZA (1) ZA782918B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997015225A1 (fr) * 1995-10-23 1997-05-01 Nikolai Serafimovich Zefirov Agent therapeutique contre les troubles neurodegeneratifs

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4451655A (en) * 1982-05-17 1984-05-29 Pfizer Inc. Process for preparing carboline derivatives and compounds used in their preparation
SE9604786D0 (sv) * 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
US6974825B1 (en) 1996-12-20 2005-12-13 Astrazeneca Canada Inc. Compounds with analgesic effect
SE9904675D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0101773D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101770D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101769D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101771D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205452A1 (es) * 1973-12-06 1976-05-07 Endo Lab Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles
JPS50126699A (fr) * 1974-03-20 1975-10-04
US4001263A (en) * 1974-04-01 1977-01-04 Pfizer Inc. 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997015225A1 (fr) * 1995-10-23 1997-05-01 Nikolai Serafimovich Zefirov Agent therapeutique contre les troubles neurodegeneratifs

Also Published As

Publication number Publication date
SU818484A3 (ru) 1981-03-30
DE2822465A1 (de) 1978-11-30
IL54755A0 (en) 1978-07-31
SE448459B (sv) 1987-02-23
SE441448B (sv) 1985-10-07
FI781612A (fi) 1978-11-24
ZA782918B (en) 1979-06-27
PT68058B (en) 1979-10-24
NO150204B (no) 1984-05-28
HU185009B (en) 1984-11-28
DD145537A5 (de) 1980-12-17
DK226678A (da) 1978-11-24
CH634321A5 (en) 1983-01-31
SE8305917D0 (sv) 1983-10-27
IE46975B1 (en) 1983-11-16
GB1586655A (en) 1981-03-25
BE867249A (fr) 1978-11-20
PL116944B1 (en) 1981-07-31
DD146186A5 (de) 1981-01-28
AU499618B1 (en) 1979-04-26
YU221782A (en) 1983-01-21
EG13590A (en) 1982-03-31
AR217688A1 (es) 1980-04-15
FI63402C (fi) 1983-06-10
PL114541B1 (en) 1981-02-28
SU843749A3 (ru) 1981-06-30
DD138321A5 (de) 1979-10-24
PL117107B1 (en) 1981-07-31
ATA369678A (de) 1982-04-15
PL206903A1 (pl) 1979-10-22
SE7803625L (sv) 1978-11-24
NO151862B (no) 1985-03-11
JPS53144600A (en) 1978-12-15
NO150204C (no) 1984-09-05
NO831790L (no) 1978-11-24
HU188802B (en) 1986-05-28
IT7823673A0 (it) 1978-05-22
LU79684A1 (fr) 1979-12-06
YU221682A (en) 1983-01-21
SU841589A3 (ru) 1981-06-23
IT1096307B (it) 1985-08-26
IL54755A (en) 1981-02-27
PL114547B1 (en) 1981-02-28
NO151862C (no) 1985-06-19
CA1094071A (fr) 1981-01-20
YU40796B (en) 1986-06-30
GR69985B (fr) 1982-07-22
IE781013L (en) 1978-11-23
FR2392023B1 (fr) 1980-11-07
JPS5711912B2 (fr) 1982-03-08
AT368995B (de) 1982-11-25
SE8305917L (sv) 1983-10-27
FI63402B (fi) 1983-02-28
DD145536A5 (de) 1980-12-17
PT68058A (en) 1978-06-01
CS207612B2 (en) 1981-08-31
AR221721A1 (es) 1981-03-13
FR2392023A1 (fr) 1978-12-22
NL7804210A (nl) 1978-11-27
NZ187333A (en) 1984-05-31
NO781770L (no) 1978-11-24
HU187782B (en) 1986-02-28
YU91478A (en) 1983-01-21
PH13756A (en) 1980-09-17
YU221882A (en) 1983-01-21
DE2822465C2 (de) 1986-08-28

Similar Documents

Publication Publication Date Title
US4146643A (en) Increasing vigilance or treating cerebral insufficiency with substituted vincamines
CA1056381A (fr) 5-ARYL-1,2,3,4-TETRAHYDRO-.gamma.-CARBOLINES
SU873883A3 (ru) Способ получени гексагидро - -карболинов или их солей
SU1333239A3 (ru) Способ получени гидрохлоридов замещенных 2- @ 4-окси-4-(п-фторфенил)бутил @ -4а,9в-транс-2,3,4,4а,5,9в-гексагидро-1Н-пиридо/4,3в/индолов
US5162335A (en) Di- and tetrahydroisoquinoline derivatives
NO744183L (fr)
US4585769A (en) Benzenesulfonyl-lactams and their use as active substances of pharmaceutical compositions
NZ307230A (en) Furo[3,4-c]pyrrole, isoindole or thieno[3,4-c]pyrrole derivatives and medicaments
Kupchan et al. Isolation and structural elucidation of 4-demethylhasubanonine, a new alkaloid from Stephania hernandifolia
US4138407A (en) 2,4 Pyrrolidinediones
CA1066706A (fr) Derives de la 14,15-dihydroeburnamenine
CA1136134A (fr) 1-hydroxyalcanamine tetrahydrocarbazoles
JPH0341079A (ja) 抗アテローム性動脈硬化症アザフロクロモン
US3868372A (en) Organomercapto-substituted polyhydro imidazo{8 1,5-a{9 pyridenes and pyride{8 1,2-c{9 pyrimidines
DE60107852T2 (de) Thienopyrrolidinone
EP0001585B1 (fr) Dérivés de pipérazino-pyrrolobenzodiazépine, leurs procédés de préparation et compositions pharmaceutiques les contenant
US4329350A (en) 1,1-Disubstituted octahydro-indolo[2,3-a]quinolizines, process for the preparation thereof and compositions containing same
US4252812A (en) 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
JPS587635B2 (ja) インドリンカゴウブツノセイゾウホウ
GB1583590A (en) Tricycle compounds
US4548947A (en) 1-(Substituted-aryl)-dihydro-1H-pyrrolizine-3,5-[2H,6H-]diones and use for reversing amnesia
US4319029A (en) Hydroxyalkanamide tetrahydrocarbazoles
US4044137A (en) 2-(Phenylthiopropyl)-5-aryl-1,2,3,4-tetrahydro-γ-carbolines
US3120538A (en) -y-bromine butyric acid ethylester
US4006164A (en) 4-Aryl-1,2,3,4-tetrahydropyrrolo[3,4-b]indoles