SE0101770D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0101770D0
SE0101770D0 SE0101770A SE0101770A SE0101770D0 SE 0101770 D0 SE0101770 D0 SE 0101770D0 SE 0101770 A SE0101770 A SE 0101770A SE 0101770 A SE0101770 A SE 0101770A SE 0101770 D0 SE0101770 D0 SE 0101770D0
Authority
SE
Sweden
Prior art keywords
sub
sup
ring
phenyl
novel compounds
Prior art date
Application number
SE0101770A
Other languages
English (en)
Inventor
William Brown
Andrew Griffin
Christopher Walpole
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0101770A priority Critical patent/SE0101770D0/sv
Publication of SE0101770D0 publication Critical patent/SE0101770D0/sv
Priority to EP02736338A priority patent/EP1395558B1/en
Priority to CZ20033090A priority patent/CZ20033090A3/cs
Priority to HU0401608A priority patent/HUP0401608A2/hu
Priority to AT02736338T priority patent/ATE313529T1/de
Priority to DE60208193T priority patent/DE60208193T2/de
Priority to IL15862902A priority patent/IL158629A0/xx
Priority to KR10-2003-7014948A priority patent/KR20040000469A/ko
Priority to US10/477,853 priority patent/US7064137B2/en
Priority to JP2002591456A priority patent/JP2005510456A/ja
Priority to ARP020101815A priority patent/AR033759A1/es
Priority to RU2003131967/04A priority patent/RU2003131967A/ru
Priority to PCT/SE2002/000945 priority patent/WO2002094783A1/en
Priority to EEP200300534A priority patent/EE200300534A/xx
Priority to PL02366390A priority patent/PL366390A1/xx
Priority to CNA028141709A priority patent/CN1620435A/zh
Priority to CA002446313A priority patent/CA2446313A1/en
Priority to SK1392-2003A priority patent/SK13922003A3/sk
Priority to BR0209669-2A priority patent/BR0209669A/pt
Priority to MXPA03010441A priority patent/MXPA03010441A/es
Priority to ZA200308637A priority patent/ZA200308637B/en
Priority to BG108331A priority patent/BG108331A/bg
Priority to CO03100167A priority patent/CO5540319A2/es
Priority to IS7031A priority patent/IS7031A/is
Priority to NO20035112A priority patent/NO20035112D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
SE0101770A 2001-05-18 2001-05-18 Novel compounds SE0101770D0 (sv)

Priority Applications (25)

Application Number Priority Date Filing Date Title
SE0101770A SE0101770D0 (sv) 2001-05-18 2001-05-18 Novel compounds
MXPA03010441A MXPA03010441A (es) 2001-05-18 2002-05-16 Derivados de 4-(fenil-(piperidin-4-il)-amino)-benzamida y sus usos para tratamiento del dolor, ansiedad o desordenes gastrointestinales.
ARP020101815A AR033759A1 (es) 2001-05-18 2002-05-16 Derivados de 4-(fenil-(piperidin-4-il)amino)benzamida
PCT/SE2002/000945 WO2002094783A1 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
HU0401608A HUP0401608A2 (hu) 2001-05-18 2002-05-16 4-[Fenil-(4-piperidinil)-amino]-benzamid-származékok, alkalmazásuk, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
AT02736338T ATE313529T1 (de) 2001-05-18 2002-05-16 4-(phenyl(piperidin-4-yl)amino) benzamidderivate und deren verwendung zur behandlung von schmerzen,angst oder gastrointestinalen störungen
DE60208193T DE60208193T2 (de) 2001-05-18 2002-05-16 4-(phenyl(piperidin-4-yl)amino) benzamidderivate und deren verwendung zur behandlung von schmerzen, angst oder gastrointestinalen störungen
IL15862902A IL158629A0 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
KR10-2003-7014948A KR20040000469A (ko) 2001-05-18 2002-05-16 4-(페닐-(피페리딘-4-일)-아미노)-벤즈아미드 유도체 및통증, 불안증 또는 위장관 장애의 치료를 위한 그의 용도
US10/477,853 US7064137B2 (en) 2001-05-18 2002-05-16 4-(Phenyl-(piperidin-4-yl)-amino)-benzamide derivaties and their use for the treatment of pain, anxiety or gastrointestinal disorders
JP2002591456A JP2005510456A (ja) 2001-05-18 2002-05-16 4−(フェニル−(ピペリジン−4−イル)−アミノ)−ベンズアミド誘導体及び疼痛、不安症又は胃腸障害の治療のためのその使用
EP02736338A EP1395558B1 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
RU2003131967/04A RU2003131967A (ru) 2001-05-18 2002-05-16 Производные 4-(фенил-(пиперидин-4-ил)-бензамида и их применение для лечения боли, тревоги или желудочно-кишечных расстройств
CZ20033090A CZ20033090A3 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
EEP200300534A EE200300534A (et) 2001-05-18 2002-05-16 4-(fenüül(piperidiin-4-üül)amino)bensamiidi derivaadid ja nende kasutamine valu, ärevuse või seedetrakti häirete raviks
PL02366390A PL366390A1 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
CNA028141709A CN1620435A (zh) 2001-05-18 2002-05-16 4-(苯基-(哌啶-4-基)-氨基)-苯甲酰胺衍生物及其在治疗疼痛、焦虑症或胃肠病中的应用
CA002446313A CA2446313A1 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
SK1392-2003A SK13922003A3 (sk) 2001-05-18 2002-05-16 4-(Fenyl-(piperidín-4-yl)-amino)benzamidové deriváty a ich požitie na liečbu bolesti, anxiety alebo gastrointestinálnych porúch
BR0209669-2A BR0209669A (pt) 2001-05-18 2002-05-16 Composto, processo para preparar o mesmo, uso de um composto, composição farmacêutica, e, métodos para o tratamento da dor, de distúrbios gastrintestinais funcionais e de lesões espinhais
ZA200308637A ZA200308637B (en) 2001-05-18 2003-11-05 4-[Phenyl-(piperidin-4-yl)-amino]-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders.
BG108331A BG108331A (bg) 2001-05-18 2003-11-07 4-(фенил-(пиперидин-4-ил)-амино)-бензамидни производни и тяхното използване за лечението на болка, потиснатост или стомашно-чревни разстройства
CO03100167A CO5540319A2 (es) 2001-05-18 2003-11-12 Derivados de 4-(fenil-(piperidin-4-il)-amino)-benzamida y sus usos para el tratamiento del dolor, la ansiedad o desordenes gastrointestinales
IS7031A IS7031A (is) 2001-05-18 2003-11-13 4-(fenýl-(píperidín-4-ýl)-amínó)-bensamíðafleiðurog notkun þeirra til meðhöndlunar á sársauka, kvíða eða truflunum í maga og þörmum
NO20035112A NO20035112D0 (no) 2001-05-18 2003-11-17 4-(fenyl-(piperidin-4-yl)-amino)-benzamidderivater og deres anvendelse vedbehandling av smerte, angst eller gastrointestinale forstyrrelser

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0101770A SE0101770D0 (sv) 2001-05-18 2001-05-18 Novel compounds

Publications (1)

Publication Number Publication Date
SE0101770D0 true SE0101770D0 (sv) 2001-05-18

Family

ID=20284173

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0101770A SE0101770D0 (sv) 2001-05-18 2001-05-18 Novel compounds

Country Status (25)

Country Link
US (1) US7064137B2 (sv)
EP (1) EP1395558B1 (sv)
JP (1) JP2005510456A (sv)
KR (1) KR20040000469A (sv)
CN (1) CN1620435A (sv)
AR (1) AR033759A1 (sv)
AT (1) ATE313529T1 (sv)
BG (1) BG108331A (sv)
BR (1) BR0209669A (sv)
CA (1) CA2446313A1 (sv)
CO (1) CO5540319A2 (sv)
CZ (1) CZ20033090A3 (sv)
DE (1) DE60208193T2 (sv)
EE (1) EE200300534A (sv)
HU (1) HUP0401608A2 (sv)
IL (1) IL158629A0 (sv)
IS (1) IS7031A (sv)
MX (1) MXPA03010441A (sv)
NO (1) NO20035112D0 (sv)
PL (1) PL366390A1 (sv)
RU (1) RU2003131967A (sv)
SE (1) SE0101770D0 (sv)
SK (1) SK13922003A3 (sv)
WO (1) WO2002094783A1 (sv)
ZA (1) ZA200308637B (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0300987D0 (sv) * 2003-04-03 2003-04-03 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
WO2005033073A2 (en) 2003-10-01 2005-04-14 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US7598261B2 (en) 2005-03-31 2009-10-06 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US7576207B2 (en) 2006-04-06 2009-08-18 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
WO2016099394A1 (en) * 2014-12-19 2016-06-23 Pharmnovo Ab Novel selective delta-opioid receptor agonists useful for the treatment of pain, anxiety and depression.

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091096A (en) * 1976-03-19 1978-05-23 Eli Lilly And Company Dinitroanilines for the control of phytopathogens
EG12406A (en) * 1976-08-12 1979-03-31 Janssen Pharmaceutica Nv Process for preparing of novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides
US4252812A (en) * 1977-05-23 1981-02-24 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
SE441448B (sv) 1977-05-23 1985-10-07 Pfizer Sett att framstella hexahydro-gamma-karbolinforeningar
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
EP0181793B1 (fr) * 1984-10-16 1988-07-27 Synthelabo Dérivés de pipéridine, leur préparation et leur application en thérapeutique
KR940003491B1 (ko) * 1989-08-10 1994-04-23 리히터 게데온 베기에스제티 기아르 알.티 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물
YU150489A (sh) * 1989-08-10 1992-12-21 W.L. Gore & Co. Gmbh. Uređaj za ispitivanje odevnih predmeta na nepromočivost
US5854245A (en) * 1996-06-28 1998-12-29 Merck & Co., Inc. Fibrinogen receptor antagonists
TW548271B (en) * 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
SE9604786D0 (sv) * 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
ATE306472T1 (de) 1997-12-24 2005-10-15 Ortho Mcneil Pharm Inc (4)-(aryl(piperidin-4-yl) aminobenzamidderivate die an delta-opioid rezeptor binden
ATE522503T1 (de) 1998-03-10 2011-09-15 Res Triangle Inst Neue opiate, herstellungsverfahren und verwendungen
SE9904675D0 (sv) * 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
BR0108965A (pt) * 2000-03-03 2002-11-26 Ortho Mcneil Pharm Inc Derivados de 3-(diarilmetileno)-8-azabiciclo[3,2,1]octano
US6556387B1 (en) * 2000-03-31 2003-04-29 Seagate Technology Llc Controlling mechanical response characteristics of a disc drive actuator by adjusting a fastener engaging the actuator shaft to vary axial force on the bearing assembly
SE0001207D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds

Also Published As

Publication number Publication date
CZ20033090A3 (en) 2004-06-16
AR033759A1 (es) 2004-01-07
CN1620435A (zh) 2005-05-25
CA2446313A1 (en) 2002-11-28
RU2003131967A (ru) 2005-05-10
ZA200308637B (en) 2005-02-07
HUP0401608A2 (hu) 2004-12-28
ATE313529T1 (de) 2006-01-15
NO20035112D0 (no) 2003-11-17
BR0209669A (pt) 2004-04-20
JP2005510456A (ja) 2005-04-21
KR20040000469A (ko) 2004-01-03
BG108331A (bg) 2004-10-29
SK13922003A3 (sk) 2004-04-06
MXPA03010441A (es) 2004-03-09
US20040152731A1 (en) 2004-08-05
EP1395558A1 (en) 2004-03-10
CO5540319A2 (es) 2005-07-29
DE60208193T2 (de) 2006-07-13
IS7031A (is) 2003-11-13
IL158629A0 (en) 2004-05-12
US7064137B2 (en) 2006-06-20
PL366390A1 (en) 2005-01-24
EP1395558B1 (en) 2005-12-21
WO2002094783A1 (en) 2002-11-28
EE200300534A (et) 2004-02-16
DE60208193D1 (de) 2006-01-26

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