HU188802B - Process for preparing trans-2-substituted-5-aryl-2,3,4, 4a,5,9b-hexahydro-1h-pyrido/4,3-b/indole derivatives - Google Patents

Process for preparing trans-2-substituted-5-aryl-2,3,4, 4a,5,9b-hexahydro-1h-pyrido/4,3-b/indole derivatives Download PDF

Info

Publication number
HU188802B
HU188802B HU822638A HU822638A HU188802B HU 188802 B HU188802 B HU 188802B HU 822638 A HU822638 A HU 822638A HU 822638 A HU822638 A HU 822638A HU 188802 B HU188802 B HU 188802B
Authority
HU
Hungary
Prior art keywords
trans
hexahydro
formula
pyrido
hydrogen
Prior art date
Application number
HU822638A
Other languages
German (de)
English (en)
Hungarian (hu)
Inventor
Willard M Welch
Original Assignee
Pfizer Inc,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc,Us filed Critical Pfizer Inc,Us
Publication of HU188802B publication Critical patent/HU188802B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU822638A 1977-05-23 1978-05-18 Process for preparing trans-2-substituted-5-aryl-2,3,4, 4a,5,9b-hexahydro-1h-pyrido/4,3-b/indole derivatives HU188802B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79939277A 1977-05-23 1977-05-23

Publications (1)

Publication Number Publication Date
HU188802B true HU188802B (en) 1986-05-28

Family

ID=25175793

Family Applications (3)

Application Number Title Priority Date Filing Date
HU822639A HU187782B (en) 1977-05-23 1978-05-18 Process for preparing trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido-/4,3-b/indole derivatives
HU78PI626A HU185009B (en) 1977-05-23 1978-05-18 Process for preparing trans-2-substituted-5-aryl-2,3,4,4a,5,9b,- hexahydro-1h-pyrido/4,3-b/ indole derivatives
HU822638A HU188802B (en) 1977-05-23 1978-05-18 Process for preparing trans-2-substituted-5-aryl-2,3,4, 4a,5,9b-hexahydro-1h-pyrido/4,3-b/indole derivatives

Family Applications Before (2)

Application Number Title Priority Date Filing Date
HU822639A HU187782B (en) 1977-05-23 1978-05-18 Process for preparing trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido-/4,3-b/indole derivatives
HU78PI626A HU185009B (en) 1977-05-23 1978-05-18 Process for preparing trans-2-substituted-5-aryl-2,3,4,4a,5,9b,- hexahydro-1h-pyrido/4,3-b/ indole derivatives

Country Status (31)

Country Link
JP (1) JPS53144600A (fi)
AR (2) AR217688A1 (fi)
AT (1) AT368995B (fi)
AU (1) AU499618B1 (fi)
BE (1) BE867249A (fi)
CA (1) CA1094071A (fi)
CH (1) CH634321A5 (fi)
CS (1) CS207612B2 (fi)
DD (4) DD145537A5 (fi)
DE (1) DE2822465C2 (fi)
DK (1) DK226678A (fi)
EG (1) EG13590A (fi)
FI (1) FI63402C (fi)
FR (1) FR2392023A1 (fi)
GB (1) GB1586655A (fi)
GR (1) GR69985B (fi)
HU (3) HU187782B (fi)
IE (1) IE46975B1 (fi)
IL (1) IL54755A (fi)
IT (1) IT1096307B (fi)
LU (1) LU79684A1 (fi)
NL (1) NL7804210A (fi)
NO (2) NO150204C (fi)
NZ (1) NZ187333A (fi)
PH (1) PH13756A (fi)
PL (5) PL117107B1 (fi)
PT (1) PT68058B (fi)
SE (2) SE441448B (fi)
SU (4) SU873883A3 (fi)
YU (4) YU91478A (fi)
ZA (1) ZA782918B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4451655A (en) * 1982-05-17 1984-05-29 Pfizer Inc. Process for preparing carboline derivatives and compounds used in their preparation
RU2106864C1 (ru) * 1995-10-23 1998-03-20 Николай Серафимович Зефиров Средство для лечения болезни альцгеймера
US6974825B1 (en) 1996-12-20 2005-12-13 Astrazeneca Canada Inc. Compounds with analgesic effect
SE9604786D0 (sv) 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
SE9904675D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0101773D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101771D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101769D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101770D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
DE20204239U1 (de) 2002-03-16 2002-05-29 Funke Kunststoffe GmbH, 48324 Sendenhorst Universal-Rohrdichtung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205452A1 (es) * 1973-12-06 1976-05-07 Endo Lab Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles
JPS50126699A (fi) * 1974-03-20 1975-10-04
US4001263A (en) * 1974-04-01 1977-01-04 Pfizer Inc. 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines

Also Published As

Publication number Publication date
IL54755A0 (en) 1978-07-31
SU873883A3 (ru) 1981-10-15
YU40796B (en) 1986-06-30
IT7823673A0 (it) 1978-05-22
FI781612A (fi) 1978-11-24
DE2822465A1 (de) 1978-11-30
IL54755A (en) 1981-02-27
SU841589A3 (ru) 1981-06-23
CA1094071A (en) 1981-01-20
SE448459B (sv) 1987-02-23
FI63402B (fi) 1983-02-28
ZA782918B (en) 1979-06-27
IE46975B1 (en) 1983-11-16
YU221782A (en) 1983-01-21
EG13590A (en) 1982-03-31
SE8305917L (sv) 1983-10-27
NO150204B (no) 1984-05-28
PL114547B1 (en) 1981-02-28
JPS53144600A (en) 1978-12-15
PL117107B1 (en) 1981-07-31
FR2392023A1 (fr) 1978-12-22
YU91478A (en) 1983-01-21
PT68058B (en) 1979-10-24
DD138321A5 (de) 1979-10-24
AR221721A1 (es) 1981-03-13
DK226678A (da) 1978-11-24
FR2392023B1 (fi) 1980-11-07
AU499618B1 (en) 1979-04-26
YU221682A (en) 1983-01-21
CH634321A5 (en) 1983-01-31
CS207612B2 (en) 1981-08-31
YU221882A (en) 1983-01-21
GR69985B (fi) 1982-07-22
NO151862C (no) 1985-06-19
PH13756A (en) 1980-09-17
AR217688A1 (es) 1980-04-15
GB1586655A (en) 1981-03-25
ATA369678A (de) 1982-04-15
IT1096307B (it) 1985-08-26
AT368995B (de) 1982-11-25
NZ187333A (en) 1984-05-31
DD145537A5 (de) 1980-12-17
SU818484A3 (ru) 1981-03-30
IE781013L (en) 1978-11-23
DE2822465C2 (de) 1986-08-28
DD145536A5 (de) 1980-12-17
FI63402C (fi) 1983-06-10
NO150204C (no) 1984-09-05
PL206903A1 (pl) 1979-10-22
SE7803625L (sv) 1978-11-24
JPS5711912B2 (fi) 1982-03-08
HU185009B (en) 1984-11-28
NO151862B (no) 1985-03-11
NO781770L (no) 1978-11-24
LU79684A1 (fr) 1979-12-06
SE441448B (sv) 1985-10-07
BE867249A (fr) 1978-11-20
NO831790L (no) 1978-11-24
PT68058A (en) 1978-06-01
PL114541B1 (en) 1981-02-28
SU843749A3 (ru) 1981-06-30
DD146186A5 (de) 1981-01-28
HU187782B (en) 1986-02-28
SE8305917D0 (sv) 1983-10-27
NL7804210A (nl) 1978-11-27
PL116944B1 (en) 1981-07-31

Similar Documents

Publication Publication Date Title
FI98367C (fi) Menetelmä uusien terapeuttisesti käyttökelpoisten trisyklisten, typpipitoisten yhdisteiden valmistamiseksi
JPH0363280A (ja) オキサジアゾール及びその塩類、痴呆を治療するそれらの用途、それらの製造法及び処方剤
EP0623621A1 (en) Oxazabicyclo derivatives and their use as 5-HT4 receptor agonists
EP0546181B1 (en) Indole derivatives and their use as serotonin antagonists
JPH04283587A (ja) 新規3環式化合物
DE69433148T2 (de) Tricyclische kondensierte heterocyclische Verbindungen zur Behandlung von seniler Demenz
HU188802B (en) Process for preparing trans-2-substituted-5-aryl-2,3,4, 4a,5,9b-hexahydro-1h-pyrido/4,3-b/indole derivatives
IE53034B1 (en) Anti-hypertensive 1-substituted spiro(piperidine-oxobenzoxazines)
IE46909B1 (en) Pyridobenzodiazepines
HU184712B (en) Process for producing dextrorotating trans-2-substituted-5-phenyl-2,3,4,4a,5,9b,hexahydro-h-pyrido-bracket-4,3,b-bracket closedindol derivatives
JPH08502283A (ja) 5−ht▲下4▼レセプターアンタゴニスト用の縮合環系n−アルキルピペリジニル−4−メチルカルボン酸エステル/アミド
JPH04295476A (ja) ジヒドロベンゾフランカルボキサミド及びその製造方法
AU2006217540B2 (en) Ocaperidone salts and pharmaceutical compositions containing the same
FI65618C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 5-ubstituerade 10,11-dihydro-5h-dibenso(a d)cyklohepten-5,1 0-miner
HU203889B (en) Process for producing heterocyclic lactame derivatives and pharmaceutical compositions containing them as active components
US4843080A (en) 1,12-disubstituted octahydroindolo[2,3-]quinolizine derivatives, pharmaceutical compositions
EP0434202B1 (en) Azabicyclo amides and esters as 5-HT3 receptor antagonists
KR830001667B1 (ko) 페닐 퀴놀리지딘의 제조방법
US3499003A (en) 3-(2-(3-aminopyrrolidinyl)-ethyl)-indoles
HU203551B (en) Process for producing oxazino- and pyrimido-acridine derivatives and pharmaceutical compositions containing tem
KR820000103B1 (ko) 트랜스-2-치환된-5-아릴-2,3,4,4a5,9b-헥사하이드로-1H-피리도[4,3-b]인돌 유도체의 제조방법
KR820000095B1 (ko) 트랜스-2-치환된-5-아릴-2,3,4,4a,5,9b-헥사하이드로-1H-피리도[4,3-b]인돌 유도체의 제조방법.
JP3819759B2 (ja) 三環式縮合複素環誘導体、その製造法および用途
RU2043991C1 (ru) Дигидробензофурановые карбоксамиды или его фармацевтически приемлемые соли и способ их получения
DE2854014A1 (de) 7,8,9,10-tetrahydrothieno eckige klammer auf 3,2-e eckige klammer zu pyrido eckige klammer auf 4,3-b eckige klammer zu indole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel