CH634321A5 - trans-5-Aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles, process for their preparation and pharmaceutical composition containing them - Google Patents

trans-5-Aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles, process for their preparation and pharmaceutical composition containing them Download PDF

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Publication number
CH634321A5
CH634321A5 CH552678A CH552678A CH634321A5 CH 634321 A5 CH634321 A5 CH 634321A5 CH 552678 A CH552678 A CH 552678A CH 552678 A CH552678 A CH 552678A CH 634321 A5 CH634321 A5 CH 634321A5
Authority
CH
Switzerland
Prior art keywords
fluoro
hexahydro
pyrido
indole
fluorophenyl
Prior art date
Application number
CH552678A
Other languages
English (en)
French (fr)
Inventor
Willard Mckowan Jun Welch
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CH634321A5 publication Critical patent/CH634321A5/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH552678A 1977-05-23 1978-05-22 trans-5-Aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles, process for their preparation and pharmaceutical composition containing them CH634321A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79939277A 1977-05-23 1977-05-23

Publications (1)

Publication Number Publication Date
CH634321A5 true CH634321A5 (en) 1983-01-31

Family

ID=25175793

Family Applications (1)

Application Number Title Priority Date Filing Date
CH552678A CH634321A5 (en) 1977-05-23 1978-05-22 trans-5-Aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles, process for their preparation and pharmaceutical composition containing them

Country Status (31)

Country Link
JP (1) JPS53144600A (fi)
AR (2) AR217688A1 (fi)
AT (1) AT368995B (fi)
AU (1) AU499618B1 (fi)
BE (1) BE867249A (fi)
CA (1) CA1094071A (fi)
CH (1) CH634321A5 (fi)
CS (1) CS207612B2 (fi)
DD (4) DD145537A5 (fi)
DE (1) DE2822465C2 (fi)
DK (1) DK226678A (fi)
EG (1) EG13590A (fi)
FI (1) FI63402C (fi)
FR (1) FR2392023A1 (fi)
GB (1) GB1586655A (fi)
GR (1) GR69985B (fi)
HU (3) HU187782B (fi)
IE (1) IE46975B1 (fi)
IL (1) IL54755A (fi)
IT (1) IT1096307B (fi)
LU (1) LU79684A1 (fi)
NL (1) NL7804210A (fi)
NO (2) NO150204C (fi)
NZ (1) NZ187333A (fi)
PH (1) PH13756A (fi)
PL (5) PL117107B1 (fi)
PT (1) PT68058B (fi)
SE (2) SE441448B (fi)
SU (4) SU873883A3 (fi)
YU (4) YU91478A (fi)
ZA (1) ZA782918B (fi)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE20204239U1 (de) 2002-03-16 2002-05-29 Funke Kunststoffe GmbH, 48324 Sendenhorst Universal-Rohrdichtung

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4451655A (en) * 1982-05-17 1984-05-29 Pfizer Inc. Process for preparing carboline derivatives and compounds used in their preparation
RU2106864C1 (ru) * 1995-10-23 1998-03-20 Николай Серафимович Зефиров Средство для лечения болезни альцгеймера
US6974825B1 (en) 1996-12-20 2005-12-13 Astrazeneca Canada Inc. Compounds with analgesic effect
SE9604786D0 (sv) 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
SE9904675D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0101773D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101771D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101769D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101770D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205452A1 (es) * 1973-12-06 1976-05-07 Endo Lab Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles
JPS50126699A (fi) * 1974-03-20 1975-10-04
US4001263A (en) * 1974-04-01 1977-01-04 Pfizer Inc. 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE20204239U1 (de) 2002-03-16 2002-05-29 Funke Kunststoffe GmbH, 48324 Sendenhorst Universal-Rohrdichtung

Also Published As

Publication number Publication date
IL54755A0 (en) 1978-07-31
SU873883A3 (ru) 1981-10-15
YU40796B (en) 1986-06-30
IT7823673A0 (it) 1978-05-22
FI781612A (fi) 1978-11-24
DE2822465A1 (de) 1978-11-30
IL54755A (en) 1981-02-27
SU841589A3 (ru) 1981-06-23
CA1094071A (en) 1981-01-20
SE448459B (sv) 1987-02-23
FI63402B (fi) 1983-02-28
ZA782918B (en) 1979-06-27
IE46975B1 (en) 1983-11-16
YU221782A (en) 1983-01-21
EG13590A (en) 1982-03-31
SE8305917L (sv) 1983-10-27
NO150204B (no) 1984-05-28
PL114547B1 (en) 1981-02-28
JPS53144600A (en) 1978-12-15
PL117107B1 (en) 1981-07-31
FR2392023A1 (fr) 1978-12-22
YU91478A (en) 1983-01-21
PT68058B (en) 1979-10-24
DD138321A5 (de) 1979-10-24
AR221721A1 (es) 1981-03-13
DK226678A (da) 1978-11-24
FR2392023B1 (fi) 1980-11-07
AU499618B1 (en) 1979-04-26
YU221682A (en) 1983-01-21
CS207612B2 (en) 1981-08-31
YU221882A (en) 1983-01-21
GR69985B (fi) 1982-07-22
NO151862C (no) 1985-06-19
PH13756A (en) 1980-09-17
HU188802B (en) 1986-05-28
AR217688A1 (es) 1980-04-15
GB1586655A (en) 1981-03-25
ATA369678A (de) 1982-04-15
IT1096307B (it) 1985-08-26
AT368995B (de) 1982-11-25
NZ187333A (en) 1984-05-31
DD145537A5 (de) 1980-12-17
SU818484A3 (ru) 1981-03-30
IE781013L (en) 1978-11-23
DE2822465C2 (de) 1986-08-28
DD145536A5 (de) 1980-12-17
FI63402C (fi) 1983-06-10
NO150204C (no) 1984-09-05
PL206903A1 (pl) 1979-10-22
SE7803625L (sv) 1978-11-24
JPS5711912B2 (fi) 1982-03-08
HU185009B (en) 1984-11-28
NO151862B (no) 1985-03-11
NO781770L (no) 1978-11-24
LU79684A1 (fr) 1979-12-06
SE441448B (sv) 1985-10-07
BE867249A (fr) 1978-11-20
NO831790L (no) 1978-11-24
PT68058A (en) 1978-06-01
PL114541B1 (en) 1981-02-28
SU843749A3 (ru) 1981-06-30
DD146186A5 (de) 1981-01-28
HU187782B (en) 1986-02-28
SE8305917D0 (sv) 1983-10-27
NL7804210A (nl) 1978-11-27
PL116944B1 (en) 1981-07-31

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PL Patent ceased